C. Patterson

发表

Stress-dependent Daxx-CHIP Interaction Suppresses the p53 Apoptotic Program*♦

Holly McDonough, P. Charles, Eleanor G. Hilliard, 2009, The Journal of Biological Chemistry.

The FoxO family in cardiac function and dysfunction.

Cam Patterson, C. Patterson, S. Ronnebaum, 2010, Annual review of physiology.

C Terminus of Hsc70-interacting Protein Promotes Smooth Muscle Cell Proliferation and Survival through Ubiquitin-mediated Degradation of FoxO1*

D. Gu, C. Patterson, Yongna Fan, 2009, The Journal of Biological Chemistry.

Comparative Effects of Paclitaxel and Rapamycin on Smooth Muscle Migration and Survival: Role of Akt-Dependent Signaling

R. Herrmann, P. Charles, Eleanor G. Hilliard, 2006, Arteriosclerosis, thrombosis, and vascular biology.

CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation.

J. Hussain, C. Pritchard, R. Marais, 2008, Molecular cell.

From the cradle to the grave: molecular chaperones that may choose between folding and degradation

D. Cyr, C. Patterson, J. Höhfeld, 2001, EMBO reports.

Gene Expression Profile Signatures Indicate a Role for Wnt Signaling in Endothelial Commitment From Embryonic Stem Cells

C. Perou, J. Rubin, P. Charles, 2006, Circulation research.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

skeletal muscle following exercise and training Alterations in oxidative gene expression in equine

David S. Paul, R. Coleman, E. Hill, 2015 .

NADPH Oxidase–Generated Reactive Oxygen Species Are Required for Stromal Cell–Derived Factor-1&agr;–Stimulated Angiogenesis

A. Portbury, C. Patterson, Liang Xie, 2014, Arteriosclerosis, thrombosis, and vascular biology.

From Machine Learning to Artificial Intelligence Applications in Cardiac Care.

David Tsay, Cam Patterson, David Tsay, 2018, Circulation.

The Bitter End: The Ubiquitin-Proteasome System and Cardiac Dysfunction

C. Patterson, G. Stouffer, M. Willis, 2007, Circulation.

Non-Targeted Metabolomics Analysis of Golden Retriever Muscular Dystrophy-Affected Muscles Reveals Alterations in Arginine and Proline Metabolism, and Elevations in Glutamic and Oleic Acid In Vivo

C. Newgard, C. Patterson, J. Kornegay, 2017, Metabolites.

Bone morphogenetic proteins and vascular differentiation

C. Patterson, M. Moser, 2005, Thrombosis and Haemostasis.

LE-PAS, a novel Arnt-dependent HLH-PAS protein, is expressed in limbic tissues and transactivates the CNS midline enhancer element.

C. Bode, C. Patterson, M. Moser, 2004, Brain research. Molecular brain research.

Retrograde transport of the glucocorticoid receptor in neurites requires dynamic assembly of complexes with the protein chaperone hsp90 and is linked to the CHIP component of the machinery for proteasomal degradation.

Jennifer M Harrell, C. Patterson, M. Galigniana, 2004, Brain research. Molecular brain research.

NF‐¿B inhibition protects against tumor‐induced cardiac atrophy in vivo

Xiaoying Yin, C. Patterson, A. Wysong, 2009, The American journal of pathology.

Suppression of Interleukin-1β-induced Nitric-oxide Synthase Promoter/Enhancer Activity by Transforming Growth Factor-β1 in Vascular Smooth Muscle Cells

C. Patterson, C. Hsieh, S. yet, 1996, The Journal of Biological Chemistry.

Regulation of the Cytoplasmic Quality Control Protein Degradation Pathway by BAG2*

C. Borchers, Holly McDonough, Shu-Bing Qian, 2005, Journal of Biological Chemistry.

Protein isolation from the developing embryonic mouse heart valve region.

C. Patterson, Yaxu Wu, Laura A Dyer, 2014, Journal of visualized experiments : JoVE.

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

P. Connell, C. Patterson, J. Höhfeld, 2000, Nature Cell Biology.

ARID1a-DNA Interactions Are Required for Promoter Occupancy by SWI/SNF

J. Brennan, T. Magnuson, J. Schisler, 2012, Molecular and Cellular Biology.

C-terminus of heat shock protein 70– interacting protein facilitates degradation of apoptosis signal-regulating kinase 1 and inhibits apoptosis signal-regulating kinase 1– dependent apoptosis

C. Patterson, J. Hwang, Chunlian Zhang, 2005, Cell stress & chaperones.

The triage of damaged proteins: degradation by the ubiquitin‐proteasome pathway or repair by molecular chaperones

P. Evans, C. Patterson, Weimin Guo, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Synthesis and comparative evaluation of novel (64)Cu-labeled high affinity cell-specific peptides for positron emission tomography imaging of tumor vasculature.

D. Lalush, K. Krajewski, C. Patterson, 2016, Biomaterials.

Development of a New Positron Emission Tomography Tracer for Targeting Tumor Angiogenesis: Synthesis, Small Animal Imaging, and Radiation Dosimetry

D. Lalush, C. Patterson, Hong Yuan, 2013, Molecules.

Efficient In Vivo Selection of a Novel Tumor-Associated Peptide from a Phage Display Library

D. Lalush, C. Patterson, C. B. Frederick, 2011, Molecules.

Genetic myostatin decrease in the golden retriever muscular dystrophy model does not significantly affect the ubiquitin proteasome system despite enhancing the severity of disease.

C. Patterson, J. Kornegay, D. Bogan, 2013, American journal of translational research.

The Ubiquitin Ligase CHIP Prevents SirT6 Degradation through Noncanonical Ubiquitination

Holly McDonough, C. Patterson, S. Ronnebaum, 2013, Molecular and Cellular Biology.

Gyrate: CCM3 Dances with a Different Angiogenic Partner

A. Portbury, C. Patterson, Laura A Dyer, 2010, Science Signaling.

TAS2R38 predisposition to bitter taste associated with differential changes in vegetable intake in response to a community-based dietary intervention

K. Robasky, J. Schisler, C. Patterson, 2018, bioRxiv.

Untargeted metabolomics analysis of ischemia–reperfusion-injured hearts ex vivo from sedentary and exercise-trained rats

C. Patterson, J. Starnes, J. Bain, 2017, Metabolomics.

Regulation of the calpain and ubiquitin‐proteasome systems in a canine model of muscular dystrophy

J. Min, C. Patterson, J. Kornegay, 2011, Muscle & nerve.

Exercise-Induced Alterations in Skeletal Muscle, Heart, Liver, and Serum Metabolome Identified by Non-Targeted Metabolomics Analysis

C. Patterson, J. Starnes, J. Bain, 2017, Metabolites.

CHIP: a link between the chaperone and proteasome systems

Holly McDonough, C. Patterson, 2003, Cell stress & chaperones.

Mechanisms of Endothelial Differentiation in Embryonic Vasculogenesis

C. Patterson, J. Ferguson, R. Kelley, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Novel Mediators and Mechanisms in Angiogenesis and Vasculogenesis Series

C. Patterson, J. Ferguson, R. Kelley, 2005 .

BMPER, a Novel Endothelial Cell Precursor-Derived Protein, Antagonizes Bone Morphogenetic Protein Signaling and Endothelial Cell Differentiation

F. Conlon, C. Bode, C. Patterson, 2003, Molecular and Cellular Biology.

BMPER is a conserved regulator of hematopoietic and vascular development in zebrafish.

C. Bode, C. Patterson, M. Moser, 2007, Journal of molecular and cellular cardiology.

PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation.

Hong Wang, Hengbin Wang, Holly McDonough, 2008, Journal of molecular and cellular cardiology.

Increasing Cardiomyocyte Atrogin-1 Reduces Aging-Associated Fibrosis and Regulates Remodeling in Vivo.

J. Schisler, C. Patterson, M. Sandri, 2018, The American journal of pathology.

Cell cycle in vasculoproliferative diseases: potential interventions and routes of delivery.

C. Patterson, V. Sriram, 2001, Circulation.

Cell Cycle in Vasculoproliferative Diseases

C. Patterson, V. Sriram, 2001 .

Selective endothelial cell attachment to peptide-modified terpolymers.

C. Patterson, S. Cooper, D. Heath, 2008, Biomaterials.

Tiny dancers

C. Patterson, S. Smyth, 2002, The Journal of cell biology.

Engineering a Ubiquitin Ligase Reveals Conformational Flexibility Required for Ubiquitin Transfer*

W. Chazin, R. Klevit, Shu-Bing Qian, 2009, The Journal of Biological Chemistry.

Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex.

Da-Zhi Wang, Holly McDonough, C. Patterson, 2004, The Journal of clinical investigation.

Hard luck stories: the reality of endothelial progenitor cells continues to fall short of the promise.

Arjun Deb, C. Patterson, 2010, Circulation.

HSP70-1 is required for interleukin-5-induced angiogenic responses through eNOS pathway

Yung-Hyun Choi, Wun-Jae Kim, C. Patterson, 2017, Scientific Reports.

Characterization of a model to independently study regression of ventricular hypertrophy.

C. Patterson, M. Rojas, C. Selzman, 2007, The Journal of surgical research.

Association for Academic Surgery, 2004 Characterization of a Model to Independently Study Regression of Ventricular Hypertrophy 1,2

C. Patterson, M. Rojas, C. Selzman, 2007 .

Carboxyl terminus of Hsp70‐interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise

Holly McDonough, J. Min, C. Patterson, 2013, Cell biochemistry and function.

Build it up-Tear it down: protein quality control in the cardiac sarcomere.

J. Schisler, A. Portbury, C. Patterson, 2008, Cardiovascular research.

Differential transcriptional regulation of the human thrombin receptor gene by the Sp family of transcription factors in human endothelial cells.

M. Runge, C. Patterson, G. Rao, 1998, The Biochemical journal.

Roles of Peroxisome Proliferator-Activated Receptors ( PPARs ) in the Heart

J. Schisler, C. Patterson, M. Willis, 2010 .

Overexpression of the Cochaperone CHIP Enhances Hsp70-Dependent Folding Activity in Mammalian Cells

H. Kampinga, C. Patterson, B. Kanon, 2003, Molecular and Cellular Biology.

MOVAS-1 cell line: a new in vitro model of vascular calcification.

C. Patterson, V. Macrae, D. Zhu, 2011, International journal of molecular medicine.

SFRP2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway

C. Perou, C. Livasy, J. Arbiser, 2009 .

PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response.

C. Patterson, Junmin Peng, Liang Xie, 2012, The Journal of clinical investigation.

Breast cancer quality control

C. Patterson, S. Ronnebaum, 2009, Nature Cell Biology.

Extracellular bone morphogenetic protein modulator BMPER and twisted gastrulation homolog 1 preserve arterial‐venous specification in zebrafish blood vessel development and regulate Notch signaling in endothelial cells

C. Bode, C. Patterson, M. Moser, 2018, The FEBS journal.

Fibroblast Growth Factor Signaling Pathway in Endothelial Cells Is Activated by BMPER to Promote Angiogenesis

C. Bode, C. Patterson, M. Moser, 2015, Arteriosclerosis, thrombosis, and vascular biology.

The ubiquitin ligase MuRF1 protects against cardiac ischemia/reperfusion injury by its proteasome-dependent degradation of phospho-c-Jun.

De-Pei Liu, C. Patterson, Hui-hua Li, 2011, The American journal of pathology.

Connecting the coronaries: how the coronary plexus develops and is functionalized.

C. Patterson, Laura A Dyer, Xinchun Pi, 2014, Developmental biology.

Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol.

D. Gingras, R. Béliveau, C. Patterson, 2003, Molecular biology of the cell.

Tear me down: role of calpain in the development of cardiac ventricular hypertrophy.

J. Schisler, A. Portbury, C. Patterson, 2011, Circulation research.

Cardiac protein folding and degradation

C. Patterson, 2005 .

Chaperone-dependent Regulation of Endothelial Nitric-oxide Synthase Intracellular Trafficking by the Co-chaperone/Ubiquitin Ligase CHIP*

W. Sessa, D. Cyr, C. Patterson, 2003, Journal of Biological Chemistry.

C-terminus of heat shock protein 70-interacting protein-dependent GTP cyclohydrolase I degradation in lambs with increased pulmonary blood flow.

J. Catravas, C. Patterson, R. Rafikov, 2011, American journal of respiratory cell and molecular biology.

Ubiquitylation of Neuronal Nitric-oxide Synthase by CHIP, a Chaperone-dependent E3 Ligase*

C. Patterson, W. Pratt, Y. Morishima, 2004, Journal of Biological Chemistry.

An Androgen Receptor NH2-terminal Conserved Motif Interacts with the COOH Terminus of the Hsp70-interacting Protein (CHIP)*

E. Wilson, C. Patterson, B. He, 2004, Journal of Biological Chemistry.

The role of ubiquitin ligases in cardiac disease.

Petra C. Kienesberger, C. Patterson, P. Kienesberger, 2014, Journal of molecular and cellular cardiology.

Chaperone Functions of the E3 Ubiquitin Ligase CHIP*

P. Muchowski, D. Cyr, C. Patterson, 2007, Journal of Biological Chemistry.

Nitric Oxide Insufficiency, Platelet Activation, and Arterial Thrombosis New Tricks for Old Dogs: Nonthrombotic Effects of Thrombin in Vessel Wall Biology Regulation of Vascular Bed–Specific Prothrombotic Potential Insights Into Mechanisms of Thrombosis From Genetic Models Molecular Pathogenesis of

M. Runge, C. Patterson, G. Stouffer, 2001 .

Wnt2 Coordinates the Commitment of Mesoderm to Hematopoietic, Endothelial, and Cardiac Lineages in Embryoid Bodies*

Da-Zhi Wang, C. Patterson, B. Wainwright, 2007, Journal of Biological Chemistry.

Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins.

Holly McDonough, C. Patterson, D. Glass, 2007, The Journal of clinical investigation.

CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity

L. Petrucelli, C. Ross, T. Dawson, 2009, Proceedings of the National Academy of Sciences.

Evidence for association of coronary sinus levels of hepatocyte growth factor and collateralization in human coronary disease.

C. Patterson, D. Lenihan, Abdulfatah Osman, 2003, American journal of physiology. Heart and circulatory physiology.

Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors

C. Patterson, M. Moser, R. Cheney, 2009, The Journal of Cell Biology.

A salty salute: progenitor cell therapies and no-option heart disease.

C. Patterson, 2006, American heart journal.

BMPER Is an Endothelial Cell Regulator and Controls Bone Morphogenetic Protein-4–Dependent Angiogenesis

H. Augustin, C. Bode, C. Zoeller, 2008, Circulation research.

Gene Expression Profiling In Rat Smooth Muscle Cells Reveals Novel Regulatory Pathways Modulated by Rapamycin and Paclitaxel

J. Parker, R. Herrmann, P. Charles, 2006 .

CHIP Represses Myocardin-Induced Smooth Muscle Cell Differentiation via Ubiquitin-Mediated Proteasomal Degradation

D. Gu, C. Patterson, Yongna Fan, 2009, Molecular and Cellular Biology.

Co-Activation of Nuclear Factor-κB and Myocardin/Serum Response Factor Conveys the Hypertrophy Signal of High Insulin Levels in Cardiac Myoblasts*

R. de Caterina, P. Ferdinandy, R. Bolli, 2014, The Journal of Biological Chemistry.

mTORC1 Links Protein Quality and Quantity Control by Sensing Chaperone Availability*♦

J. Yewdell, J. Bennink, Shu-Bing Qian, 2010, The Journal of Biological Chemistry.

Rise above: muscle ring-finger-1 (MURF1) regulation of cardiomyocyte size and energy metabolism.

A. Portbury, C. Patterson, M. Willis, 2011, Transactions of the American Clinical and Climatological Association.

Insulin Levels in Cardiac Myoblasts Conveys the Hypertrophy Signal of High Myocardin / Serum Response Factor B and κ Co-Activation of Nuclear Factor-Gene Regulation :

P. Ferdinandy, R. Bolli, C. Patterson, 2014 .

CHIP activates HSF1 and confers protection against apoptosis and cellular stress

V. Godfrey, L. Neckers, Holly McDonough, 2003, The EMBO journal.

Ubiquitin-proteasome degradation of serum- and glucocorticoid-regulated kinase-1 (SGK-1) is mediated by the chaperone-dependent E3 ligase CHIP.

C. Patterson, Deanna R. Brickley, S. Conzen, 2006, The Biochemical journal.

Ataxia and hypogonadism caused by the loss of ubiquitin ligase activity of the U box protein CHIP.

J. Schisler, Holly McDonough, A. Portbury, 2014, Human molecular genetics.

C-terminal Hsp-interacting protein slows androgen receptor synthesis and reduces its rate of degradation.

C. Patterson, C. Cardozo, C. Michaud, 2003, Archives of biochemistry and biophysics.

Younger than yesterday: is vascular senescence a two-way street?

M. Runge, C. Patterson, N. Madamanchi, 2004, Circulation research.

Postischemic Recovery of Contractile Function is Impaired in SOD2+/− but Not SOD1+/− Mouse Hearts

C. Patterson, G. Asimakis, S. Lick, 2002, Circulation.

MMI-0100 inhibits cardiac fibrosis in myocardial infarction by direct actions on cardiomyocytes and fibroblasts via MK2 inhibition.

C. Patterson, Liang Xie, M. Willis, 2014, Journal of molecular and cellular cardiology.

Diminished GATA4 Protein Levels Contribute to Hyperglycemia-induced Cardiomyocyte Injury*

T. O’Connell, C. Patterson, Satoru Kobayashi, 2007, Journal of Biological Chemistry.

You spin me round: MafBx/Atrogin-1 feeds forward on FOXO transcription factors (like a record)

J. Schisler, C. Patterson, M. Willis, 2008, Cell cycle.

Muscle ring finger protein-1 inhibits PKCε activation and prevents cardiomyocyte hypertrophy

Holly McDonough, C. Patterson, Hui-hua Li, 2004, The Journal of cell biology.

Seek and destroy: The ubiquitin-proteasome system in cardiac disease

J. Schisler, C. Patterson, M. Willis, 2009, Current hypertension reports.

Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease.

J. Schisler, C. Patterson, M. Willis, 2008, Future cardiology.

Cardiac Muscle Ring Finger-1 Increases Susceptibility to Heart Failure In Vivo

J. Schisler, P. Charles, Eleanor G. Hilliard, 2009, Circulation research.

Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1‐mediated gene expression in vivo

J. Schisler, Eleanor G. Hilliard, C. Patterson, 2014, Cell biochemistry and function.

Fenofibrate unexpectedly induces cardiac hypertrophy in mice lacking MuRF1.

J. Schisler, C. Patterson, Luge Li, 2016, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

Diggin′ on U(biquitin): A Novel Method for the Identification of Physiological E3 Ubiquitin Ligase Substrates

M. Gautel, J. Schisler, C. Patterson, 2013, Cell Biochemistry and Biophysics.

The Ubiquitin Proteasome System Regulates Cell Signaling and Protein Quality Control in Cardiovascular Development and Disease

C. Patterson, M. Willis, J. Homeister, 2010 .

NADPH oxidase- generated ROS are required for SDF-1 α stimulated angiogenesis Short title: NOX is an angiogenic regulator

Xi, A. Portbury, C. Patterson, 2014 .

1 Fenofibrate Induced Cardiac Fibrosis in Mice 2 Deficient in the Protein Quality Control Regulator , 3 CHIP 4

O. Ilkayeva, C. Newgard, C. Patterson, 2018 .

Adverse Effects of Fenofibrate in Mice Deficient in the Protein Quality Control Regulator, CHIP

O. Ilkayeva, C. Newgard, J. Schisler, 2018, Journal of cardiovascular development and disease.

An Oral Selective Alpha-1A Adrenergic Receptor Agonist Prevents Doxorubicin Cardiotoxicity

B. Jensen, P. Simpson, C. Patterson, 2017, JACC. Basic to translational science.

Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ

C. Ballantyne, C. Patterson, Liang Xie, 2017, Nature Communications.

Disappearance of cyclin A correlates with permanent withdrawal of cardiomyocytes from the cell cycle in human and rat hearts.

R. Schlegel, W. S. Lee, C. Patterson, 1995, The Journal of clinical investigation.

The expanding world of post-translational modifications.

C. Patterson, E. Murphy, 2012, Journal of molecular and cellular cardiology.

Krüppel-like factor 15 regulates BMPER in endothelial cells.

C. Bode, C. Patterson, H. Pahl, 2010, Cardiovascular research.

Effects of the kinase inhibitor sorafenib on heart, muscle, liver and plasma metabolism in vivo using non‐targeted metabolomics analysis

C. Newgard, B. Jensen, C. Patterson, 2017, British journal of pharmacology.

Zinc fingers in the pizza pie aorta.

C. Patterson, J. Homeister, 2008, Circulation research.

Angiotensin II induces gene transcription through cell-type-dependent effects on the nuclear factor-kappaB (NF-kappaB) transcription factor.

M. Runge, C. Patterson, M. Jamaluddin, 2000, Molecular and cellular biochemistry.

Cystic fibrosis transmembrane conductance regulator as a model substrate to study endoplasmic reticulum protein quality control in mammalian cells.

C. Fan, D. Cyr, C. Patterson, 2005, Methods in molecular biology.

Ultrasound Molecular Imaging of Secreted Frizzled Related Protein-2 Expression in Murine Angiosarcoma

R. Mumper, P. Dayton, C. Patterson, 2014, PloS one.

Hold me tight: The role of the HSP family of chaperones in cardiac disease

C. Patterson, M. Willis, 2011 .

Suppression of interleukin-1beta-induced nitric-oxide synthase promoter/enhancer activity by transforming growth factor-beta1 in vascular smooth muscle cells. Evidence for mechanisms other than NF-kappaB.

C. Patterson, C. Hsieh, S. yet, 1996, The Journal of biological chemistry.

Catecholamine-Induced Vascular Wall Growth Is Dependent on Generation of Reactive Oxygen Species

C. Patterson, J. Faber, N. Madamanchi, 2004, Circulation research.

Bone Morphogenetic Protein-Modulator BMPER Regulates Endothelial Barrier Function

S. Grundmann, C. Bode, C. Patterson, 2016, Inflammation.

CHIP Deﬁciency Decreases Longevity, with Accelerated Aging Phenotypes Accompanied by Altered Protein Quality Control (cid:1)

N. Sharpless, J. Min, A. Portbury, 2008 .

Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques

C. Patterson, M. Willis, 2012 .

Chaperone-dependent E3 ligase CHIP ubiquitinates and mediates proteasomal degradation of soluble guanylyl cyclase.

J. Catravas, Shu-Bing Qian, C. Patterson, 2007, American journal of physiology. Heart and circulatory physiology.

Faculty Opinions recommendation of SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis.

C. Patterson, 2008 .

M. Runge, C. Patterson, Young-Choon Lee, 2004, Experimental Gerontology.

HIV therapies and atherosclerosis: answers or questions?

M. Runge, C. Patterson, N. Madamanchi, 2002, Arteriosclerosis, thrombosis, and vascular biology.

HIV Therapies and Atherosclerosis

M. Runge, C. Patterson, N. Madamanchi, 2002 .

Evidence for Vascular Mitochondrial Toxicity Induced by PIs : Fact or Fancy ?

M. Runge, C. Patterson, N. Madamanchi, 2002 .

Angiogenesis and Atherosclerosis

C. Patterson, 2010 .

The Ponzo effect: endothelial progenitor cells appear on the horizon.

C. Patterson, 2003, Circulation.

The Role of Thrombin in Vascular Development

C. Patterson, M. Moser, 2009 .

Abciximab‐Associated Thrombocytopenia After Previous Tirofiban‐Related Thrombocytopenia

C. Patterson, J. Rodgers, M. Dorsch, 2006, Pharmacotherapy.

A foldable CFTRΔF508 biogenic intermediate accumulates upon inhibition of the Hsc70–CHIP E3 ubiquitin ligase

C. Fan, D. Cyr, C. Patterson, 2004, The Journal of cell biology.

CHIP regulates Aquaporin‐2 Quality Control and Body Water Homeostasis

J. Schisler, C. Patterson, T. Pisitkun, 2017, Journal of the American Society of Nephrology : JASN.

Reconstitution of CHIP E3 ubiquitin ligase activity.

D. Cyr, C. Patterson, H. Ren, 2011, Methods in molecular biology.

The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins.

Cam Patterson, Michael Hutton, Leonard Petrucelli, 2007, The Journal of clinical investigation.

BMPER regulates retinal angiogenesis in vivo in a mouse model of oxygen-induced retinopathy

C. Patterson, M. Moser, R. Ren, 2011 .

CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70

Holly McDonough, Shu-Bing Qian, D. Cyr, 2006, Nature.

Novel role of C terminus of Hsc70‐interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5‐mediated degradation of inducible cAMP early repressor

C. Molina, C. Patterson, Chen Yan, 2010 .

C. Molina, C. Patterson, Chen Yan, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

BMPER-induced BMP signaling promotes coronary artery remodeling.

C. Patterson, M. Moser, Yaxu Wu, 2014, Developmental biology.

Cardiac muscle ring finger-1--friend or foe?

C. Patterson, M. Willis, M. Zungu, 2010, Trends in cardiovascular medicine.

A novel ex vivo culture method for the embryonic mouse heart.

C. Patterson, Laura A Dyer, 2013, Journal of visualized experiments : JoVE.

Faculty Opinions recommendation of Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomyopathy.

C. Patterson, 2007 .

, Availability Quantity Control by Sensing Chaperone mTORC 1 Links Protein Quality and Protein Structure and Folding

J. Yewdell, J. Bennink, C. Patterson, 2010 .

SDF-1α stimulates JNK3 activity via eNOS-dependent nitrosylation of MKP7 to enhance endothelial migration

A. Portbury, C. Patterson, J. Ferguson, 2009, Proceedings of the National Academy of Sciences.

The ATF site mediates downregulation of the cyclin A gene during contact inhibition in vascular endothelial cells

C. Patterson, J. Tsai, C. Hsieh, 1995, Molecular and cellular biology.

Vezf1/DB1 Is an Endothelial Cell-specific Transcription Factor That Regulates Expression of the Endothelin-1 Promoter*

T. Quertermous, C. Patterson, Yaxu Wu, 2001, The Journal of Biological Chemistry.

Is a U-box-dependent E 3 Ubiquitin Ligase IDENTIFICATION OF Hsc 70 AS A TARGET FOR UBIQUITYLATION *

D. Cyr, C. Patterson, J. Höhfeld, 2001 .

Heart factory or fiction?: cardiac progenitor cells and regeneration.

B. Jensen, C. Patterson, 2013, Circulation.

The Human Herpesvirus 8 Homolog of Epstein-Barr Virus SM Protein (KS-SM) Is a Posttranscriptional Activator of Gene Expression

C. Patterson, V. Ruvolo, A. Gupta, 2000, Journal of Virology.

The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

D. Cyr, C. Patterson, Wenyue Zhang, 2000, Nature Cell Biology.

Structural basis of nucleotide exchange and client binding by the novel Hsp70-cochaperone Bag2

J. Nix, Zhen Xu, C. Patterson, 2009 .

Genomic structure of the human KDR/flk-1 gene

C. Patterson, Yaxu Wu, C. Ballinger, 1998, Mammalian Genome.

Selection and initial characterization of novel peptide ligands that bind specifically to human blood outgrowth endothelial cells.

C. Patterson, S. Cooper, A. N. Veleva, 2007, Biotechnology and bioengineering.

Proteotoxicity and cardiac dysfunction.

C. Patterson, M. Willis, 2013, The New England journal of medicine.

CHIP, a cochaperone/ubiquitin ligase that regulates protein quality control, is required for maximal cardioprotection after myocardial infarction in mice.

L. Michael, C. Patterson, Zhelong Xu, 2005, American journal of physiology. Heart and circulatory physiology.

MicroRNA-21 mediates high phosphate-induced endothelial cell apoptosis.

C. Patterson, Szymon L Wiernek, G. Qi, 2018, American journal of physiology. Cell physiology.

PTP-ε, a tyrosine phosphatase expressed in endothelium, negatively regulates endothelial cell proliferation

M. Runge, C. Patterson, N. Madamanchi, 2001 .

PTP- e , a tyrosine phosphatase expressed in endothelium, negatively regulates endothelial cell proliferation

M. Runge, C. Patterson, N. Madamanchi, 2001 .

Principles of molecular cardiology

M. Runge, C. Patterson, 2005 .

Partners in crime: how two Sox proteins cooperate to specify arterial fate.

C. Patterson, Suk-Won Jin, 2008, Circulation research.

Twin layers of lightning: a new role for the chaperone Hsp90 in angiogenesis.

C. Patterson, Xinchun Pi, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Search and destroy: the role of protein quality control in maintaining cardiac function.

C. Patterson, 2006, Journal of molecular and cellular cardiology.

Shear Stress Reduces Protease Activated Receptor-1 Expression in Human Endothelial Cells

K. Nguyen, L. McIntire, M. Runge, 2001, Annals of Biomedical Engineering.

Genetic Complexity of Mitral Valve Prolapse Revealed by Clinical and Genetic Evaluation of a Large Family.

Christian R. Tilley, E. Lange, J. Berg, 2017, The Journal of heart valve disease.

Vascular Endothelial Growth Factor Induces Heparin-binding Epidermal Growth Factor-like Growth Factor in Vascular Endothelial Cells*

E. Haber, C. Patterson, N. Sibinga, 1998, The Journal of Biological Chemistry.

BMP activity controlled by BMPER regulates the proinflammatory phenotype of endothelium.

S. Grundmann, C. Bode, C. Patterson, 2011, Blood.

Mitochondrial Integrity and Function in Atherogenesis

M. Runge, S. Ballinger, C. Patterson, 2002, Circulation.

The role of BMPs in endothelial cell function and dysfunction

C. Patterson, Laura A Dyer, Xinchun Pi, 2014, Trends in Endocrinology & Metabolism.

Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP

Holly McDonough, C. Patterson, Malia B. Potts, 2005, The Journal of cell biology.

Life is a pattern: vascular assembly within the embryo.

C. Patterson, M. Moser, J. Heinke, 2012, Frontiers in bioscience.

Brothers and sisters: molecular insights into arterial-venous heterogeneity.

J. Schisler, A. Portbury, C. Patterson, 2008, Circulation research.

Stimulation of a Vascular Smooth Muscle Cell NAD(P)H Oxidase by Thrombin

C. Bode, M. Runge, C. Patterson, 1999, The Journal of Biological Chemistry.

A critical role for muscle ring finger-1 in acute lung injury-associated skeletal muscle wasting.

M. Crow, L. King, M. Messi, 2012, American journal of respiratory and critical care medicine.

Development of the Endothelium: An Emphasis on Heterogeneity

C. Patterson, Laura A Dyer, Laura Dyer1, 2010, Seminars in thrombosis and hemostasis.

Down-regulation of the Mixed-lineage Dual Leucine Zipper-bearing Kinase by Heat Shock Protein 70 and Its Co-chaperone CHIP*

C. Patterson, R. Proulx, K. Robitaille, 2006, Journal of Biological Chemistry.

Differential Activation of Mitogenic Signaling Pathways in Aortic Smooth Muscle Cells Deficient in Superoxide Dismutase Isoforms

M. Runge, C. Patterson, N. Madamanchi, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Up and Down Regulation of the Stress Response by the Co-Chaperone Ubiquitin Ligase CHIP

Shu-Bing Qian, C. Patterson, Shu‐Bing Qian, 2007 .

CX3CR1 Deficiency Impairs Dendritic Cell Accumulation in Arterial Intima and Reduces Atherosclerotic Burden

P. Liu, C. Patterson, D. Patel, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Induction of Apoptosis by Pyrrolidinedithiocarbamate and N-Acetylcysteine in Vascular Smooth Muscle Cells (*)

R. Schlegel, E. Haber, W. S. Lee, 1996, The Journal of Biological Chemistry.

Molecular Chaperones and the Ubiquitin–Proteasome System

C. Patterson, J. Höhfeld, 2008 .

Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

C. Patterson, S. Alberti, J. Höhfeld, 2001, Current Biology.

Identification of CHIP, a Novel Tetratricopeptide Repeat-Containing Protein That Interacts with Heat Shock Proteins and Negatively Regulates Chaperone Functions

P. Connell, C. Patterson, Zhaoyong Hu, 1999, Molecular and Cellular Biology.

Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure

Michael D. Schneider, Zhongliang Deng, Elizabeth P. Murchison, 2008, Proceedings of the National Academy of Sciences.

PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban.

M. Entman, G. Taffet, X. Wehrens, 2015, The Journal of clinical investigation.

Depletion of PHD3 Protects Heart from Ischemia/Reperfusion Injury by Inhibiting Cardiomyocyte Apoptosis

C. Patterson, Liang Xie, M. Willis, 2015, Journal of molecular and cellular cardiology.

Into the heart: the emerging role of the ubiquitin-proteasome system.

C. Patterson, M. Willis, 2006, Journal of molecular and cellular cardiology.

Ankyrin repeat and SOCS box containing protein 4 (Asb-4) colocalizes with insulin receptor substrate 4 (IRS4) in the hypothalamic neurons and mediates IRS4 degradation

M. Mulholland, C. Patterson, Weizhen Zhang, 2011, BMC Neuroscience.

The Human KDR/flk-1 Gene Contains a Functional Initiator Element That Is Bound and Transactivated by TFII-I*

C. Patterson, Yaxu Wu, 1999, The Journal of Biological Chemistry.

Emerging Roles of Vascular Endothelium in Metabolic Homeostasis.

C. Patterson, Liang Xie, Xinchun Pi, 2018, Circulation research.

Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2

J. Nix, Zhen Xu, C. Patterson, 2008, Nature Structural &Molecular Biology.

Back to your heart: ubiquitin proteasome system-regulated signal transduction.

A. Portbury, C. Patterson, S. Ronnebaum, 2012, Journal of molecular and cellular cardiology.

Ubiquitylation - Dependent Signaling in Heart Disease

A. Portbury, C. Patterson, S. Ronnebaum, 2012 .

The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching

Victoria L. Bautch, Cam Patterson, K. Kallianos, 2008, The Journal of cell biology.

BMPER Protein Is a Negative Regulator of Hepcidin and Is Up-regulated in Hypotransferrinemic Mice*

M. Arno, C. Patterson, R. Simpson, 2011, The Journal of Biological Chemistry.

Induction of Heme Oxygenase-1 Expression in Vascular Smooth Muscle Cells

C. Patterson, S. Folta, C. Hsieh, 1997, The Journal of Biological Chemistry.

Recovery from decompensated heart failure is associated with a distinct, phase-dependent gene expression profile.

C. Patterson, M. Rojas, Ruhang Tang, 2012, The Journal of surgical research.

Tobacco use induces anti-apoptotic, proliferative patterns of gene expression in circulating leukocytes of Caucasian males

J. Parker, J. Schisler, P. Charles, 2008, BMC Medical Genomics.

New tricks for old dogs: nonthrombotic effects of thrombin in vessel wall biology.

M. Runge, C. Patterson, G. Stouffer, 2001, Circulation research.

Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu

L. Neckers, C. Patterson, M. Marcu, 2002, Proceedings of the National Academy of Sciences of the United States of America.

CHIP Is a U-box-dependent E3 Ubiquitin Ligase

D. Cyr, C. Patterson, J. Höhfeld, 2001, The Journal of Biological Chemistry.

PDTC, metal chelating compound, induces G1 phase cell cycle arrest in vascular smooth muscle cells through inducing p21Cip1 expression: Involvement of p38 mitogen activated protein kinase

Yung-Hyun Choi, C. Patterson, Young-Choon Lee, 2004, Journal of cellular physiology.

p68RacGAP Is a Novel GTPase-activating Protein That Interacts with Vascular Endothelial Zinc Finger-1 and Modulates Endothelial Cell Capillary Formation*

K. Wennerberg, C. Der, C. Patterson, 2004, Journal of Biological Chemistry.

Adenosine produces nitric oxide and prevents mitochondrial oxidant damage in rat cardiomyocytes.

R. Mueller, C. Patterson, P. Boysen, 2005, Cardiovascular research.

The opening act: vasculogenesis and the origins of circulation.

C. Patterson, Suk-Won Jin, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Vasculogenesis and the Origins of Circulation

C. Patterson, Suk-Won Jin, 2009 .

AtCHIP, a U-Box-Containing E3 Ubiquitin Ligase, Plays a Critical Role in Temperature Stress Tolerance in Arabidopsis1

C. Patterson, Juqiang Yan, Jing Wang, 2003, Plant Physiology.

The Co-chaperone Carboxyl Terminus of Hsp70-interacting Protein (CHIP) Mediates α-Synuclein Degradation Decisions between Proteasomal and Lysosomal Pathways*

B. Hyman, P. McLean, C. Patterson, 2005, Journal of Biological Chemistry.

CHIP Protects from the Neurotoxicity of Expanded and Wild-type Ataxin-1 and Promotes Their Ubiquitination and Degradation*

Ismael Al-Ramahi, Juan Botas, Huda Y. Zoghbi, 2006, Journal of Biological Chemistry.

Deletion of the Ubiquitin Ligase CHIP Leads to the Accumulation, But Not the Aggregation, of Both Endogenous Phospho- and Caspase-3-Cleaved Tau Species

Wen-Lang Lin, Guy A. Caldwell, Dennis W. Dickson, 2006, The Journal of Neuroscience.

Activates Metabolic Genes Controlled by Mechanistic Target of Rapamycin Cardiac Energy Dependence on Glucose Increases Metabolites Related to Glutathione and

David S. Paul, R. Coleman, J. Sebolt-Leopold, 2015 .

Gene Regulation and Arteriosclerosis: Are Developmental Programs Reactivated in Vascular Disease?

C. Patterson, 1999, Thrombosis and Haemostasis.

Nuclear Protein Interactions with the Human KDR/flk-1 Promoter in Vivo

E. Haber, M. Runge, C. Patterson, 1997, The Journal of Biological Chemistry.

Downregulation of vascular endothelial growth factor receptors by tumor necrosis factor-alpha in cultured human vascular endothelial cells.

E. Haber, C. Patterson, W. Endege, 1996, The Journal of clinical investigation.

Induction of Vascular Endothelial Growth Factor Gene Expression by Interleukin-1 in Rat Aortic Smooth Muscle Cells (*)

C. Patterson, J. Tsai, C. Hsieh, 1995, The Journal of Biological Chemistry.

Cloning and Functional Analysis of the Promoter for KDR/flk-1, a Receptor for Vascular Endothelial Growth Factor(*)

E. Haber, C. Patterson, C. Hsieh, 1995, The Journal of Biological Chemistry.

A Vascular Gene Trap Screen Defines RasGRP3 as an Angiogenesis-Regulated Gene Required for the Endothelial Response to Phorbol Esters

W. Stanford, C. Patterson, A. Anderson, 2004, Molecular and Cellular Biology.

Response to Phorbol Esters Gene Required for the Endothelial RasGRP 3 as an Angiogenesis-Regulated A Vascular Gene Trap Screen Defines

W. Stanford, C. Patterson, A. Anderson, 2022 .

ATP stimulates MMP-2 release from human aortic smooth muscle cells via JNK signaling pathway.

C. Patterson, R. Boucher, P. B. Rich, 2006, American journal of physiology. Heart and circulatory physiology.

Expansion of protein interaction maps by phage peptide display using MDM2 as a prototypical conformationally flexible target protein.

T. Hupp, H. Shimizu, C. Patterson, 2004, Journal of molecular biology.

A noncoding RNA regulates human protease-activated receptor-1 gene during embryogenesis.

Cam Patterson, Sung-Kwon Moon, M. Runge, 2002, Biochimica et biophysica acta.

Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I

Cam Patterson, Ranjana Arya, Holly McDonough, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Tumorigenesis and Neoplastic Progression Molecular Characterization of Human Breast Tumor Vascular Cells

C. Fan, C. Perou, Zhiyuan Hu, 2008 .

Arrest of endotoxin-induced hypotension by transforming growth factor beta1.

C. Lowenstein, E. Haber, W. S. Lee, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Using Community-Based Participatory Research Principles to Develop More Understandable Recruitment and Informed Consent Documents in Genomic Research

J. Schisler, C. Patterson, A. Ammerman, 2015, PloS one.

Thrombin Regulates Vascular Smooth Muscle Cell Growth and Heat Shock Proteins via the JAK-STAT Pathway*

M. Runge, C. Patterson, N. Madamanchi, 2001, The Journal of Biological Chemistry.

Clinical Evidence Supports a Protective Role for CXCL5 in Coronary Artery Disease.

J. Schisler, B. Jensen, Eleanor G. Hilliard, 2017, The American journal of pathology.

Minireview: hey U(PS): metabolic and proteolytic homeostasis linked via AMPK and the ubiquitin proteasome system.

J. Schisler, C. Patterson, S. Ronnebaum, 2014, Molecular endocrinology.

A Novel Monoclonal Antibody to Secreted Frizzled-Related Protein 2 Inhibits Tumor Growth

R. Mumper, Eleanor G. Hilliard, C. Patterson, 2013, Molecular Cancer Therapeutics.

HoxB5 Is an Upstream Transcriptional Switch for Differentiation of the Vascular Endothelium from Precursor Cells

C. Patterson, M. Moser, V. Bautch, 2003, Molecular and Cellular Biology.

Gene expression profiles identify a role for cyclooxygenase 2-dependent prostanoid generation in BMP6-induced angiogenic responses.

Hong Wang, P. Charles, C. Patterson, 2006, Blood.

Defective valvulogenesis in HB‐EGF and TACE‐null mice is associated with aberrant BMP signaling

David C. Lee, S. Sunnarborg, A. Chang, 2003, The EMBO journal.

Break the Cycle: The Role of Cell-Cycle Modulation in the Prevention of Vasculoproliferative Diseases

C. Patterson, J. Ferguson, 2003, Cell cycle.

Sequential Quality-Control Checkpoints Triage Misfolded Cystic Fibrosis Transmembrane Conductance Regulator

C. Fan, D. Cyr, C. Patterson, 2006, Cell.

Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors

C. Patterson, M. Moser, R. Cheney, 2007, The Journal of cell biology.

Interferon-γ-mediated Inhibition of Cyclin A Gene Transcription Is Independent of Individual cis-Acting Elements in the Cyclin A Promoter*

E. Haber, C. Patterson, N. Sibinga, 1999, The Journal of Biological Chemistry.

The ubiquitin-proteasome system and cardiovascular disease.

C. Patterson, A. Lerman, J. Herrmann, 2012, Progress in molecular biology and translational science.

Sent to Destroy: The Ubiquitin Proteasome System Regulates Cell Signaling and Protein Quality Control in Cardiovascular Development and Disease

C. Patterson, M. Willis, J. Homeister, 2010, Circulation research.

Protein quality control: U-box-containing E3 ubiquitin ligases join the fold.

D. Cyr, C. Patterson, J. Höhfeld, 2002, Trends in biochemical sciences.

Drug‐induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy

A. Citri, Y. Yarden, L. Neckers, 2002, The EMBO journal.

LRP1-Dependent BMPER Signaling Regulates Lipopolysaccharide-Induced Vascular Inflammation

C. Patterson, N. Eissa, Liang Xie, 2017, Arteriosclerosis, thrombosis, and vascular biology.

The Ubiquitin Ligase ASB4 Promotes Trophoblast Differentiation through the Degradation of ID2

C. Patterson, J. Ferguson, Yaxu Wu, 2014, PloS one.

ASB4 Is a Hydroxylation Substrate of FIH and Promotes Vascular Differentiation via an Oxygen-Dependent Mechanism

Hong Wang, P. Charles, C. Patterson, 2007, Molecular and Cellular Biology.

CHIP protects against cardiac pressure overload through regulation of AMPK.

J. Schisler, D. Cyr, C. Patterson, 2013, The Journal of clinical investigation.

Antagonism and synergy between extracellular BMP modulators Tsg and BMPER balance blood vessel formation

C. Bode, C. Patterson, M. Moser, 2013, Journal of Cell Science.

CHIP Deficiency Decreases Longevity, with Accelerated Aging Phenotypes Accompanied by Altered Protein Quality Control

N. Sharpless, J. Min, A. Portbury, 2008, Molecular and Cellular Biology.

Bone morphogenetic protein modulator BMPER is highly expressed in malignant tumors and controls invasive cell behavior

C. Bode, M. Werner, S. Lassmann, 2012, Oncogene.

Even flow: shear cues vascular development.

Cam Patterson, C. Patterson, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Ubiquitin-Proteasome Protocols

D. Cyr, C. Patterson, 2005, Methods in Molecular Biology™.

The ubiquitin ligase MuRF1 regulates PPARα activity in the heart by enhancing nuclear export via monoubiquitination

D. Lalush, C. Newgard, J. Schisler, 2015, Molecular and Cellular Endocrinology.

Lysine 48-Linked Polyubiquitination of Organic Anion Transporter-1 Is Essential for Its Protein Kinase C–Regulated Endocytosis

C. Patterson, Qiang Zhang, G. You, 2013, Molecular Pharmacology.

Atherogenesis and Aging

C. Patterson, 2006 .

Regression of pressure-induced left ventricular hypertrophy is characterized by a distinct gene expression profile.

P. Charles, C. Patterson, M. Rojas, 2009, The Journal of thoracic and cardiovascular surgery.

A Combined Strategy To Reduce Restenosis for Vascular Tissue Engineering Applications

Cam Patterson, Shih-Horng Su, K. Nguyen, 2006, Biotechnology progress.

Combinatorial Selection of Cell-Specific Peptides by Phage Display Experiments

C. Patterson, S. Cooper, A. N. Veleva, 2005 .

Bone Morphogenetic Protein-Modulator BMPER Regulates Endothelial Barrier Function

S. Grundmann, C. Bode, C. Patterson, 2017, Inflammation.

BMPER regulates cardiomyocyte size and vessel density in vivo.

J. Schisler, C. Patterson, M. Willis, 2013, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

ERK signaling is a central regulator for BMP-4 dependent capillary sprouting.

C. Bode, T. Krauss, C. Patterson, 2007, Cardiovascular research.

Jcb: Correction Sequential Roles for Myosin-x in Bmp6-dependent Fi Lopodial Extension, Migration, and Activation of Bmp Receptors

C. Patterson, M. Moser, R. Cheney, 2009 .

Inhibition of BMP activity protects epithelial barrier function in lung injury

S. Grundmann, C. Bode, C. Patterson, 2013, Journal of Pathology.

Bmper Inhibits Endothelial Expression of Inflammatory Adhesion Molecules and Protects Against Atherosclerosis

J. Schisler, C. Patterson, M. Moser, 2012, Arteriosclerosis, thrombosis, and vascular biology.

BMPER Is Upregulated by Statins and Modulates Endothelial Inflammation by Intercellular Adhesion Molecule–1

C. Bode, C. Patterson, M. Moser, 2010, Arteriosclerosis, thrombosis, and vascular biology.

A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling

L. Attisano, C. Patterson, M. Moser, 2009, The Journal of cell biology.

Angiotensin II induces gene transcription through cell-type-dependent effects on the nuclear factor-κB (NF-κB) transcription factor

M. Runge, C. Patterson, M. Jamaluddin, 2004, Molecular and Cellular Biochemistry.

Bone Morphogenetic Protein Endothelial Cell Precursor–Derived Regulator Regulates Retinal Angiogenesis In Vivo in a Mouse Model of Oxygen-Induced Retinopathy

C. Patterson, M. Moser, M. Hartnett, 2011, Arteriosclerosis, thrombosis, and vascular biology.

CHIP and HSPs interact with β-APP in a proteasome-dependent manner and influence Aβ metabolism

K. Kosik, C. Patterson, H. Band, 2007 .

CHIP and HSPs interact with beta-APP in a proteasome-dependent manner and influence Abeta metabolism.

K. Kosik, C. Patterson, H. Band, 2007, Human molecular genetics.

A New Gun in Town: The U Box Is a Ubiquitin Ligase Domain

Cam Patterson, C. Patterson, 2002, Science's STKE.

Angiotensin II induces gene transcription through cell-type-dependent effects on the nuclear factor-k

M. Runge, C. Patterson, M. Jamaluddin, 2000 .

Therapeutic options for premature coronary artery disease

C. Patterson, A. Person, 2008, Current treatment options in cardiovascular medicine.

Secreted frizzle-related protein 2 stimulates angiogenesis via a calcineurin/NFAT signaling pathway.

C. Perou, C. Livasy, J. Arbiser, 2009, Cancer research.

Stat3 orchestrates interaction between endothelial and tumor cells and inhibition of Stat3 suppresses brain metastasis of breast cancer cells

K. Aldape, C. Patterson, R. Sawaya, 2015, Oncotarget.

The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle.

S. Rakhilin, C. Patterson, D. Glass, 2007, Cell metabolism.

TAS2R38 Predisposition to Bitter Taste Associated with Differential Changes in Vegetable Intake in Response to a Community-Based Dietary Intervention

K. Robasky, J. Schisler, C. Patterson, 2018, G3: Genes, Genomes, Genetics.

Applicability of Precision Medicine Approaches to Managing Hypertension in Rural Populations

Jacqueline R. Halladay, K. Robasky, W. Jones, 2018, Journal of personalized medicine.

Thrombin and vascular development: a sticky subject.

C. Patterson, M. Moser, 2003, Arteriosclerosis, thrombosis, and vascular biology.

ATVB In Focus Extracellular Mediators in Atherosclerosis and Thrombosis

C. Patterson, M. Moser, 2003 .

Extracellular Mediators in Atherosclerosis and Thrombosis

C. Patterson, 2003 .

Akt and CHIP coregulate tau degradation through coordinated interactions

L. Petrucelli, J. Cheng, M. Birnbaum, 2008, Proceedings of the National Academy of Sciences.

Regulation of AMPK by the ubiquitin proteasome system.

J. Schisler, C. Patterson, C. McCudden, 2011, The American journal of pathology.

High CO2 Levels Cause Skeletal Muscle Atrophy via AMP-activated Kinase (AMPK), FoxO3a Protein, and Muscle-specific Ring Finger Protein 1 (MuRF1)*

J. Sznajder, Yuan Cheng, C. Patterson, 2015, The Journal of Biological Chemistry.

levels cause skeletal muscle atrophy via AMPK , FoxO 3 a and muscle-specific ring finger protein 1 ( MuRF 1 )

J. Sznajder, C. Patterson, G. Gusarova, 2015 .

High CO2 Levels Cause Skeletal Muscle Atrophy via AMP-activated Kinase (AMPK), FoxO3a Protein, and Muscle-specific Ring Finger Protein 1 (MuRF1)*

J. Sznajder, Yuan Cheng, C. Patterson, 2015, The Journal of Biological Chemistry.

Reactive Oxygen Species Regulate Heat-Shock Protein 70 via the JAK/STAT Pathway

M. Runge, C. Patterson, N. Madamanchi, 2001, Arteriosclerosis, thrombosis, and vascular biology.

Cyclic Strain Increases Protease-Activated Receptor-1 Expression in Vascular Smooth Muscle Cells

K. Nguyen, L. McIntire, M. Runge, 2001, Hypertension.

Stable Patterns of Gene Expression Regulating Carbohydrate Metabolism Determined by Geographic Ancestry

J. Parker, J. Schisler, P. Charles, 2009, PloS one.

Proteotoxicity and cardiac dysfunction--Alzheimer's disease of the heart?

Cam Patterson, C. Patterson, M. Willis, 2013, The New England journal of medicine.

HoxB5 induces endothelial sprouting in vitro and modifies intussusceptive angiogenesis in vivo involving angiopoietin-2.

C. Bode, C. Zoeller, C. Patterson, 2009, Cardiovascular research.

CHIP-dependent p53 regulation occurs specifically during cellular senescence.

C. Patterson, E. Gonos, V. Trachana, 2011, Free radical biology & medicine.

BMPER Promotes Epithelial-Mesenchymal Transition in the Developing Cardiac Cushions

C. Patterson, M. Moser, Yaxu Wu, 2015, PloS one.

CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases.

C. Patterson, E. Wiertz, M. Correia, 2009, Archives of biochemistry and biophysics.

Emerging evidence of coding mutations in the ubiquitin–proteasome system associated with cerebellar ataxias

J. Schisler, C. Patterson, S. Ronnebaum, 2014, Human Genome Variation.

Non-Targeted Metabolomics Analysis of the Effects of Tyrosine Kinase Inhibitors Sunitinib and Erlotinib on Heart, Muscle, Liver and Serum Metabolism In Vivo

B. Jensen, C. Patterson, G. Johnson, 2017, Metabolites.

The Role of Calcineurin/NFAT in SFRP2 Induced Angiogenesis—A Rationale for Breast Cancer Treatment with the Calcineurin Inhibitor Tacrolimus

Cam Patterson, David B. Darr, Eleanor G. Hilliard, 2011, PloS one.

Brain CHIP: removing the culprits in neurodegenerative disease.

L. Petrucelli, C. Patterson, Dennis Dickson, 2007, Trends in molecular medicine.

Cardiac Energy Dependence on Glucose Increases Metabolites Related to Glutathione and Activates Metabolic Genes Controlled by Mechanistic Target of Rapamycin

David S. Paul, R. Coleman, J. Schisler, 2015, Journal of the American Heart Association.

Muscle ring finger 1 mediates cardiac atrophy in vivo.

Cam Patterson, Craig H Selzman, C. Patterson, 2009, American journal of physiology. Heart and circulatory physiology.

Muscle Ring Finger 1, but not Muscle Ring Finger 2, Regulates Cardiac Hypertrophy In Vivo

Cam Patterson, Monte S. Willis, Da-Zhi Wang, 2007, Circulation research.

New insights into bone morphogenetic protein signaling: focus on angiogenesis

J. Schisler, C. Patterson, I. Moreno-Miralles, 2009, Current opinion in hematology.

Stabilization of integrin‐linked kinase by the Hsp90‐CHIP axis impacts cellular force generation, migration and the fibrotic response

M. Mann, T. Geiger, C. Patterson, 2013, The EMBO journal.

Loss of CHIP Expression Perturbs Glucose Homeostasis and Leads to Type II Diabetes through Defects in Microtubule Polymerization and Glucose Transporter Localization

C. Newgard, J. Schisler, Holly McDonough, 2016, bioRxiv.

Tearin' Up My Heart: Proteolysis in the Cardiac Sarcomere*

Cam Patterson, A. Portbury, C. Patterson, 2011, The Journal of Biological Chemistry.

Hold Me Tight: Role of the Heat Shock Protein Family of Chaperones in Cardiac Disease

C. Patterson, M. Willis, 2010, Circulation.

Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16

W. Chazin, J. Schisler, Holly McDonough, 2018, PLoS genetics.

Welcome to the machine: a cardiologist's introduction to protein folding and degradation.

Cam Patterson, D. Cyr, C. Patterson, 2002, Circulation.

Blood pressure–associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding

A. Viera, J. Schisler, C. Patterson, 2017, The Journal of clinical investigation.

Changes in protein function underlie the disease spectrum in patients with CHIP mutations

J. Schisler, C. Patterson, K. Scaglione, 2019, The Journal of Biological Chemistry.

CHIP−/−-Mouse Liver: Adiponectin-AMPK-FOXO-Activation Overrides CYP2E1-Elicited JNK1-Activation, Delaying Onset of NASH: Therapeutic Implications

C. Patterson, M. Correia, J. Grenert, 2016, Scientific Reports.

Genetics in Cardiovascular Disease

M. Runge, C. Patterson, 2010 .

2-methoxyestradiol inhibits the anaphase-promoting complex and protein translation in human breast cancer cells.

C. Fan, G. Sledge, C. Borchers, 2007, Cancer research.

Evaluating age-associated phenotypes in a mouse model of protein dyshomeostasis.

J. Min, C. Patterson, 2011, Methods.

Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of cerebellar CHIPopathy

W. Chazin, J. Schisler, Holly McDonough, 2018, bioRxiv.

SKELETAL MUSCLE MITOCHONDRIAL ALTERATIONS IN CARBOXYL TERMINUS OF HSC70 INTERACTING PROTEIN (CHIP) -/- MICE.

J. Schisler, C. Patterson, M. Willis, 2016, African journal of cellular pathology.

Running Title: CHIP Noncanonically Ubiquitinates SirT6 3

Holly McDonough, C. Patterson, S. Ronnebaum, 2013 .

A foldable CFTR F 508 biogenic intermediate accumulates upon inhibition of the Hsc 70 – CHIP E 3 ubiquitin ligase

C. Fan, D. Cyr, C. Patterson, 2004 .

Carboxyl terminus of Hsp70‐interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise

J. Min, C. Patterson, M. Willis, 2013 .

Recombinant Human Interleukin-11 Treatment Enhances Collateral Vessel Growth After Femoral Artery Ligation

C. Patterson, J. Faber, S. Winnik, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

p90RSK Targets the ERK5-CHIP Ubiquitin E3 Ligase Activity in Diabetic Hearts and Promotes Cardiac Apoptosis and Dysfunction

J. Taunton, C. Molina, C. Patterson, 2012, Circulation research.

The transcription factor HoxB5 stimulates vascular remodelling in a cytokine-dependent manner.

S. Grundmann, C. Bode, C. Patterson, 2014, Cardiovascular research.

LRP1-Dependent Endocytic Mechanism Governs the Signaling Output of the Bmp System in Endothelial Cells and in Angiogenesis

G. Bu, A. Portbury, C. Patterson, 2012, Circulation research.

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

The neuronal transcription factor NPAS4 is a strong inducer of sprouting angiogenesis and tip cell formation

C. Bode, C. Patterson, M. Moser, 2017, Cardiovascular research.

MuRF1 Inhibits JNK Signaling in Cardiac Ischemia Reperfusion injury by Degrading Phosphorylated cJun

C. Patterson, Hui-hua Li, Luge Li, 2008 .

The Polymyositis-Scleroderma Autoantigen Interacts with the Helix-Loop-Helix Proteins E12 and E47*

E. Haber, C. Patterson, W. Endege, 1997, The Journal of Biological Chemistry.

Diggin′ on U(biquitin): A Novel Method for the Identification of Physiological E3 Ubiquitin Ligase Substrates

M. Gautel, J. Schisler, C. Patterson, 2013, Cell Biochemistry and Biophysics.

p47phox is required for atherosclerotic lesion progression in ApoE(-/-) mice.

S. Holland, E. Yeh, M. Runge, 2001, The Journal of clinical investigation.

Cardiovascular complications of cancer therapy: diagnosis, pathogenesis, and management.

Michael S Ewer, Edward T H Yeh, H. Gibbs, 2004, Circulation.

Universal mouse reference RNA derived from neonatal mice.

Chunlian Zhang, Cam Patterson, C. Patterson, 2004, BioTechniques.

Torturing a blood vessel.

C. Patterson, 2009, Nature medicine.

Regulation of ankyrin repeat and suppressor of cytokine signalling box protein 4 expression in the immortalized murine endothelial cell lines MS1 and SVR: a role for tumour necrosis factor alpha and oxygen

A. Portbury, C. Patterson, Yaxu Wu, 2011, Cell biochemistry and function.

Regulation of ASB4 expression in the immortalized murine endothelial cell lines MS1 and SVR: a role for TNF- α and oxygen

A. Portbury, C. Patterson, Yaxu Wu, 2011 .

A Good Idea: A Physician’s Perspective on Genetic Counseling for Hypertrophic Cardiomyopathy

C. Patterson, 2009, Journal of cardiovascular translational research.

Carboxyl terminus of Hsp70‐interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise

J. Min, C. Patterson, M. Willis, 2013 .

PTP-epsilon, a tyrosine phosphatase expressed in endothelium, negatively regulates endothelial cell proliferation.

M. Runge, C. Patterson, N. Madamanchi, 2001, American Journal of Physiology. Heart and Circulatory Physiology.

Direct identification of ubiquitination sites on ubiquitin-conjugated CHIP using MALDI mass spectrometry.

L. Neckers, C. Patterson, R. Cotter, 2005, Journal of proteome research.

Tobacco use induces anti-apoptotic, proliferative patterns of gene expression in circulating leukocytes of Caucasian males

J. Parker, J. Schisler, P. Charles, 2008, BMC Medical Genomics.

Enhanced expression of vascular endothelial growth factor in human SaOS-2 osteoblast-like cells and murine osteoblasts induced by insulin-like growth factor I.

C. Patterson, J. Rubin, H. Wang, 1996, Endocrinology.

Hydrogen peroxide- and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells.

B. Van Houten, M. Runge, S. Ballinger, 2000, Circulation research.

Endothelial Biomedicine: Endothelial Cell Differentiation and Vascular Development in Mammals

C. Patterson, 2007 .

ARID1a-DNA Interactions Are Required for Promoter Occupancy by SWI/SNF

J. Brennan, T. Magnuson, J. Schisler, 2012, Molecular and Cellular Biology.

Cells Complex and Protein Translation in Human Breast Cancer 2-Methoxyestradiol Inhibits the Anaphase-Promoting

C. Fan, G. Sledge, C. Borchers, 2007 .

The Ubiquitin Proteasome System Regulates Cell Signaling and Protein Quality Control in Cardiovascular Development and Disease

C. Patterson, M. Willis, J. Homeister, 2010 .

Bmper Inhibits Endothelial Expression of Inflammatory Adhesion Molecules and Protects Against Atherosclerosis

J. Schisler, C. Patterson, M. Moser, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Mice (bmper Mice) Led to a More Severe Phenotype Compared with Bmper Bmper Inhibits Endothelial Expression of Inflammatory Adhesion Molecules and Protects against Atherosclerosis Materials and Methods Animals and Diets Lesion Quantification Calcification Quantification Elisa Measurements Cell Cultur

J. Schisler, C. Patterson, M. Moser, 2022 .

Things have changed: cell cycle dysregulation and smooth muscle cell dysfunction in atherogenesis

C. Patterson, 2002, Ageing Research Reviews.

The oxidative paradox: another piece in the puzzle.

M. Runge, C. Patterson, N. Madamanchi, 2000, Circulation research.

The opening act: vasculogenesis and the origins of circulation.

C. Patterson, Suk-Won Jin, 2009, Arteriosclerosis, thrombosis, and vascular biology.

A critical role for muscle ring finger-1 in acute lung injury-associated skeletal muscle wasting.

M. Crow, O. Delbono, C. Patterson, 2012, American journal of respiratory and critical care medicine.

Tobacco use induces anti-apoptotic, proliferative patterns of gene expression in circulating leukocytes of Caucasian males

J. Schisler, P. Charles, Eleanor G. Hilliard, 2008, BMC Medical Genomics.

CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity

L. Petrucelli, C. Ross, T. Dawson, 2009, Proceedings of the National Academy of Sciences of the United States of America.

Faculty Opinions recommendation of Gi alpha 1-mediated cardiac electrophysiological remodeling and arrhythmia in hypertrophic cardiomyopathy.

C. Patterson, 2007 .

Ataxia and hypogonadism caused by the loss of ubiquitin ligase activity of the U box protein CHIP.

J. Schisler, Holly McDonough, A. Portbury, 2014, Human molecular genetics.

Brothers and sisters: molecular insights into arterial-venous heterogeneity.

J. Schisler, A. Portbury, C. Patterson, 2008, Circulation research.

Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins

Holly McDonough, C. Patterson, D. Glass, 2022, The Journal of clinical investigation.

Muscle ring finger protein-1 inhibits PKCε activation and prevents cardiomyocyte hypertrophy

Holly McDonough, C. Patterson, R. Arya, 2004, The Journal of cell biology.

Hard luck stories: the reality of endothelial progenitor cells continues to fall short of the promise.

Arjun Deb, C. Patterson, 2010, Circulation.

Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP

Holly McDonough, C. Patterson, Malia B. Potts, 2005, The Journal of cell biology.

Differential regulation of protease activated receptor-1 and tissue plasminogen activator expression by shear stress in vascular smooth muscle cells.

L V McIntire, K. Nguyen, L. McIntire, 1998, Circulation research.

BMPER Is Upregulated by Statins and Modulates Endothelial Inflammation by Intercellular Adhesion Molecule–1

C. Bode, C. Patterson, M. Moser, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Krüppel-like factor 15 regulates BMPER in endothelial cells.

C. Bode, C. Patterson, H. Pahl, 2010, Cardiovascular research.

Selective endothelial cell attachment to peptide-modified terpolymers.

C. Patterson, D. Heath, A. N. Veleva, 2008, Biomaterials.

Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors

C. Patterson, M. Moser, R. Cheney, 2007, The Journal of cell biology.

Differential Drug-eluting Stent Effects in Patients with Diabetes - Bench-to-bedside Evidence for Neointimal Suppression and Restenosis Reduction

A. Finn, D. Baim, C. Patterson, 2010 .

Inhibition of BMP activity protects epithelial barrier function in lung injury

S. Grundmann, C. Bode, C. Patterson, 2013, The Journal of pathology.

MOVAS-1 cell line: a new in vitro model of vascular calcification.

C. Patterson, Dongxing Zhu, N. Mackenzie, 2011, International Journal of Molecular Medicine.

Applicability of Precision Medicine Approaches to Managing Hypertension in Rural Populations

Jacqueline R. Halladay, K. Robasky, W. Jones, 2018, Journal of personalized medicine.