J. van der Kaay

发表

The lipid phosphatase activity of PTEN is critical for its tumor supressor function.

M. Wigler, M. Myers, N. Tonks, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Metabolic switching of PI3K-dependent lipid signals.

I. Batty, J. van der Kaay, C. Downes, 2007, Biochemical Society transactions.

Essential Role of Phosphoinositide 3-Kinase in Leptin-inducedK ATP Channel Activation in the Rat CRI-G1 Insulinoma Cell Line*

J. van der Kaay, C. Downes, N. McKay, 2000, The Journal of Biological Chemistry.

Maintenance of PtdIns45P2 pools under limiting inositol conditions, as assessed by liquid chromatography-tandem mass spectrometry and PtdIns45P2 mass evaluation in Ras-transformed cells.

D. Corda, J. van der Kaay, D. Rotilio, 2002, European journal of cancer.

Insulin regulation of hepatic insulin-like growth factor-binding protein-1 (IGFBP-1) gene expression and mammalian target of rapamycin (mTOR) signalling is impaired by the presence of hydrogen peroxide.

J. van der Kaay, C. Sutherland, Satish Patel, 2002, The Biochemical journal.

The Role of Dynamin and Its Binding Partners in Coated Pit Invagination and Scission

J. van der Kaay, C. Downes, E. Smythe, 2001, The Journal of cell biology.

A Novel, Rapid, and Highly Sensitive Mass Assay for Phosphatidylinositol 3,4,5-Trisphosphate (PtdIns(3,4,5)P3) and Its Application to Measure Insulin-stimulated PtdIns(3,4,5)P3 Production in Rat Skeletal Muscle in Vivo*

I. Batty, J. van der Kaay, C. Downes, 1997, The Journal of Biological Chemistry.

The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphosphate in vivo.

Alexander G. Gray, J. van der Kaay, C. Downes, 1999, The Biochemical journal.

Insulin activates protein kinase B, inhibits glycogen synthase kinase‐3 and activates glycogen synthase by rapamycin‐insensitive pathways in skeletal muscle and adipose tissue

P. Cohen, J. van der Kaay, C. Downes, 1997, FEBS letters.

Stereospecificity of inositol hexakisphosphate dephosphorylation by Paramecium phytase.

P. V. van Haastert, J. van der Kaay, 1995, The Biochemical journal.

dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1

E. Hafen, J. van der Kaay, C. Downes, 2002, Nature cell biology.

The control of phosphatidylinositol 3,4-bisphosphate concentrations by activation of the Src homology 2 domain containing inositol polyphosphate 5-phosphatase 2, SHIP2.

I. Batty, J. van der Kaay, C. Downes, 2007, The Biochemical journal.

Dictyostelium discoideum contains three inositol monophosphatase activities with different substrate specificities and sensitivities to lithium.

P. V. van Haastert, J. van der Kaay, J. Bergsma, 1996, The Biochemical journal.

Role of phospholipase C in Dictyostelium: formation of inositol 1,4,5‐trisphosphate and normal development in cells lacking phospholipase C activity.

G. Mayr, J. van der Kaay, P. V. Haastert, 1994, The EMBO journal.

Chemoattractant and guanosine 5'-[gamma-thio]triphosphate induce the accumulation of inositol 1,4,5-trisphosphate in Dictyostelium cells that are labelled with [3H]inositol by electroporation.

P. V. van Haastert, J. van der Kaay, L. Penning, 1989, The Biochemical journal.

Nucleus-associated phosphorylation of Ins(1,4,5)P3 to InsP6 in Dictyostelium.

P. V. van Haastert, J. van der Kaay, J. Wesseling, 1995, The Biochemical journal.

Desalting inositolpolyphosphates by dialysis.

P. V. van Haastert, J. van der Kaay, 1995, Analytical Biochemistry.

Distinct Phosphatidylinositol 3-Kinase Lipid Products Accumulate upon Oxidative and Osmotic Stress and Lead to Different Cellular Responses*

J. van der Kaay, C. Downes, A. Gray, 1999, The Journal of Biological Chemistry.

Dynamics and function of the inositolcycle in Dictyostelium discoideum.

P. V. van Haastert, J. van der Kaay, A. Bominaar, 1991, Developmental genetics.