H. Sirma

发表

Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

Yoichi Taya, Andreas Möller, H. Zentgraf, 2002, Nature Cell Biology.

Determinants of Hepadnaviral Species and Liver Cell Tropism

H. Will, H. Sirma, A. Funk, 2005 .

Itinerary of Hepatitis B Viruses: Delineation of Restriction Points Critical for Infectious Entry

H. Will, H. Sirma, A. Funk, 2004, Journal of Virology.

Identification of a structural motif crucial for infectivity of hepatitis B viruses.

H. Will, E. Hildt, H. Sirma, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer.

V. Beneš, C. von Kalle, R. Eils, 2013, Cancer cell.

Overexpression of the chromatin remodeler death-domain-associated protein in prostate cancer is an independent predictor of early prostate-specific antigen recurrence.

C. Plass, G. Sauter, T. Schlomm, 2013, Human pathology.

Recurrent deletion of 3p13 targets multiple tumour suppressor genes and defines a distinct subgroup of aggressive ERG fusion‐positive prostate cancers

S. Kurtz, G. Sauter, T. Schlomm, 2013, The Journal of pathology.

Genomic deletion of PTEN is associated with tumor progression and early PSA recurrence in ERG fusion-positive and fusion-negative prostate cancer.

C. Plass, F. Saad, S. Kurtz, 2012, The American journal of pathology.

Proteasome-Dependent Degradation of Daxx by the Viral E1B-55K Protein in Human Adenovirus-Infected Cells

P. Blanchette, R. Everett, H. Sirma, 2010, Journal of Virology.

Replication of ICP0-Null Mutant Herpes Simplex Virus Type 1 Is Restricted by both PML and Sp100

R. Everett, H. Sirma, A. Orr, 2007, Journal of Virology.

Replication of ICP0-Null Mutant Herpes Simplex Virus Type 1 Is Restricted by both PML and Sp100

R. Everett, H. Sirma, A. Orr, 2007, Journal of Virology.

PML isoforms I and II participate in PML-dependent restriction of HSV-1 replication

R. Everett, H. Sirma, J. Heeren, 2011, Journal of Cell Science.

SUMO modification of E1B-55K oncoprotein regulates isoform-specific binding to the tumour suppressor protein PML

R. Everett, H. Sirma, T. Dobner, 2010, Oncogene.

CHD1 loss negatively influences metastasis-free survival in R0-resected prostate cancer patients and promotes spontaneous metastasis in vivo

G. Sauter, R. Simon, H. Huland, 2021, Cancer gene therapy.

Inhibition of experimental HCC growth in mice by use of the kinase inhibitor DMAT.

C. Hellerbrand, H. Sirma, M. Ocker, 2011, International journal of oncology.

Genomic deletion of MAP3K7 at 6q12-22 is associated with early PSA recurrence in prostate cancer and absence of TMPRSS2:ERG fusions

J. Korbel, C. Plass, G. Sauter, 2013, Modern Pathology.

CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer.

G. Sauter, T. Schlomm, R. Simon, 2013, Cancer research.

Human telomerase reverse transcriptase promoter is activated during liver regeneration and hepatocyte proliferation

Jitendra Kumar Meena, L. Zender, K. Rudolph, 2012 .

The promoter of human telomerase reverse transcriptase is activated during liver regeneration and hepatocyte proliferation.

Jitendra Kumar Meena, L. Zender, K. Rudolph, 2011, Gastroenterology.

NS1- and Minute Virus of Mice-Induced Cell Cycle Arrest: Involvement of p53 and p21cip1

J. Sobczak-Thépot, H. Sirma, C. Bréchot, 2001, Journal of Virology.

Direct Association and Nuclear Import of the Hepatitis B Virus X Protein with the NF-κB Inhibitor IκBα

A. Israël, H. Sirma, C. Bréchot, 1999, Molecular and Cellular Biology.

Direct association and nuclear import of the hepatitis B virus X protein with the NF-kappaB inhibitor IkappaBalpha.

A. Israël, H. Sirma, C. Bréchot, 1999, Molecular and cellular biology.

New Hepatitis B Virus of Cranes That Has an Unexpected Broad Host Range

H. Will, H. Sirma, L. Cova, 2003, Journal of Virology.

Assembly and budding of a hepatitis B virus is mediated by a novel type of intracellular vesicles

H. Will, H. Sirma, A. Funk, 2007, Hepatology.

Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL-positive CML cells.

T. Brümmendorf, S. Balabanov, J. Dierlamm, 2011, Experimental hematology.

Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression

T. Hofmann, H. Will, A. Möller, 2003, Oncogene.

Cytosol is the prime compartment of hepatitis B virus X protein where it colocalizes with the proteasome

A. Israël, H. Sirma, C. Bréchot, 1998, Oncogene.

Dose response effects of 2-acetylaminofluorene on DNA damage, cytotoxicity, cell proliferation and neoplastic conversion in rat liver.

R. Gebhardt, G. Williams, H. Sirma, 1993, Cancer letters.

Nuclear Translocation of Papillomavirus Minor Capsid Protein L2 Requires Hsc70

H. Sirma, Luise Florin, M. Sapp, 2004, Journal of Virology.

Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx

H. Sirma, C. Bréchot, D. Kremsdorf, 1999, Oncogene.

Evidence from nature: interspecies spread of heron hepatitis B viruses.

A. Ludwig, H. Will, H. Sirma, 2005, The Journal of general virology.

Duck Hepatitis B Virus Requires Cholesterol for Endosomal Escape during Virus Entry

H. Sirma, R. Reimer, A. Funk, 2008, Journal of Virology.

Avian hepatitis B viruses: molecular and cellular biology, phylogenesis, and host tropism.

H. Will, H. Sirma, A. Funk, 2007, World journal of gastroenterology.

Selection and Counterselection of the rtI233V Adefovir Resistance Mutation during Antiviral Therapy

M. Helm, J. Rockstroh, H. Sirma, 2009, Journal of Clinical Microbiology.

Does pre-treatment with lamivudine prime for adefovir resistance of hepatitis B virus infection?

H. Sirma, W. Gerlich, A. Funk, 2007, Journal of Antimicrobial Chemotherapy.

Assembly and budding of a hepatitis B virus is mediated by a novel type of intracellular vesicles

H. Will, H. Sirma, A. Funk, 2007, Hepatology.

Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report

J. van Lunzen, J. Rockstroh, H. Sirma, 2010, Viruses.

More on hepatitis B virus rtI233V mutation and resistance to adefovir.

H. Sirma, O. Schildgen, 2014, The New England journal of medicine.

ERG Status Is Unrelated to PSA Recurrence in Radically Operated Prostate Cancer in the Absence of Antihormonal Therapy

H. Schlüter, G. Sauter, T. Schlomm, 2011, Clinical Cancer Research.

Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness

R. Simon, M. Dobbelstein, H. Will, 2016, EMBO reports.

CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer.

G. Sauter, T. Schlomm, R. Simon, 2013, Cancer research.

Prevalence of chromosomal rearrangements involving non-ETS genes in prostate cancer.

J. Korbel, G. Sauter, T. Schlomm, 2015, International journal of oncology.

PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase

M. Mitchell, M. Mattéi, A. Mégarbané, 2006, Journal of Cell Science.

TGF-b signaling

Tim Beißbarth, Holger Sültmann, Ulrike Korf, 2022 .

Loss of CDKN1B/p27Kip1 expression is associated with ERG fusion-negative prostate cancer, but is unrelated to patient prognosis

A. Haese*, G. Sauter, T. Schlomm, 2013, Oncology letters.

βIII-tubulin overexpression is an independent predictor of prostate cancer progression tightly linked to ERG fusion status and PTEN deletion.

G. Sauter, T. Schlomm, S. Steurer, 2014, The American journal of pathology.

High RNA-binding motif protein 3 expression is an independent prognostic marker in operated prostate cancer and tightly linked to ERG activation and PTEN deletions.

A. Haese*, G. Sauter, T. Schlomm, 2014, European journal of cancer.

High nuclear karyopherin α 2 expression is a strong and independent predictor of biochemical recurrence in prostate cancer patients treated by radical prostatectomy

G. Sauter, T. Schlomm, S. Steurer, 2014, Modern Pathology.

High lysophosphatidylcholine acyltransferase 1 expression independently predicts high risk for biochemical recurrence in prostate cancers

G. Sauter, T. Schlomm, R. Simon, 2013, Molecular oncology.

SPINK1 expression is tightly linked to 6q15‐ and 5q21‐deleted ERG‐fusion negative prostate cancers but unrelated to PSA recurrence

G. Sauter, T. Schlomm, S. Steurer, 2013, The Prostate.

Reduced CD147 expression is linked to ERG fusion-positive prostate cancers but lacks substantial impact on PSA recurrence in patients treated by radical prostatectomy.

G. Sauter, T. Schlomm, S. Steurer, 2013, Experimental and molecular pathology.

Cysteine-rich secretory protein 3 overexpression is linked to a subset of PTEN-deleted ERG fusion-positive prostate cancers with early biochemical recurrence

G. Sauter, T. Schlomm, S. Steurer, 2013, Modern Pathology.

Loss of pSer2448‐mTOR expression is linked to adverse prognosis and tumor progression in ERG‐fusion‐positive cancers

G. Sauter, T. Schlomm, R. Simon, 2013, International journal of cancer.

Intratumoral heterogeneity of KRAS mutation is rare in non-small-cell lung cancer.

G. Sauter, A. Marx, T. Clauditz, 2013, Experimental and molecular pathology.

PML is required for homeodomain-interacting protein kinase 2 (HIPK2)-mediated p53 phosphorylation and cell cycle arrest but is dispensable for the formation of HIPK domains.

T. Hofmann, H. Will, A. Möller, 2003, Cancer research.

CHD1 loss negatively influences metastasis-free survival in R0-resected prostate cancer patients and promotes spontaneous metastasis in vivo

G. Sauter, R. Simon, H. Huland, 2021, Cancer Gene Therapy.

Mx1 GTPase accumulates in distinct nuclear domains and inhibits influenza A virus in cells that lack promyelocytic leukaemia protein nuclear bodies.

P. Pandolfi, H. Sirma, O. Engelhardt, 2004, The Journal of general virology.

Strong expression of the neuronal transcription factor FOXP2 is linked to an increased risk of early PSA recurrence in ERG fusion-negative cancers

G. Sauter, T. Schlomm, S. Steurer, 2013, Journal of Clinical Pathology.

Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness

R. Simon, M. Dobbelstein, H. Will, 2018, EMBO reports.

Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.

H. Sirma, M. Ocker, G. Tiegs, 2012, Oncology reports.

High c-MET expression is frequent but not associated with early PSA recurrence in prostate cancer

G. Sauter, T. Schlomm, R. Simon, 2012, Experimental and therapeutic medicine.

Non-linearity of neoplastic conversion induced in rat liver by low exposures to diethylnitrosamine.

R. Gebhardt, G. Williams, H. Sirma, 1993, Carcinogenesis.

Matrix Conditions and KLF2-Dependent Induction of Heme Oxygenase-1 Modulate Inhibition of HCV Replication by Fluvastatin

R. Bartenschlager, J. Schrader, A. Lohse, 2014, PloS one.

Strain- and sex-specific variations in hepatic glutamine synthetase activity and distribution in rats and mice.

R. Gebhardt, G. Williams, H. Sirma, 2008, Liver.

Inhibition by gonadectomy of effects of 2-acetylaminofluorene in livers of male, but not female rats.

R. Gebhardt, G. Williams, H. Sirma, 1993, Carcinogenesis.

Expression of mutated hepatitis B virus X genes in human hepatocellular carcinomas

H. Dienes, H. Sirma, C. Bréchot, 1999, International journal of cancer.

Strong and Selective Inhibitors of Hepatitis B Virus Replication among Novel N4-Hydroxy- and 5-Methyl-β-l-Deoxycytidine Analogues

H. Will, H. Sirma, A. Funk, 2007, Antimicrobial Agents and Chemotherapy.

Prevalence of chromosomal rearrangements involving non-ETS genes in prostate cancer.

J. Korbel, G. Sauter, T. Schlomm, 2015, International journal of oncology.

Proteasome-Dependent Degradation of Daxx by the Viral E1B-55K Protein in Human Adenovirus-Infected Cells

P. Blanchette, R. Everett, H. Sirma, 2010, Journal of Virology.

Isolation and molecular characterization of hepatitis B virus X‐protein from a baculovirus expression system

E. Hildt, H. Sirma, C. Eckerskorn, 1997, Hepatology.