H. Düssmann

发表

Single-cell Fluorescence Resonance Energy Transfer Analysis Demonstrates That Caspase Activation during Apoptosis Is a Rapid Process

Markus Rehm, Jochen H. M. Prehn, R. Jänicke, 2002, The Journal of Biological Chemistry.

Dominant-negative Suppression of HNF-1α Results in Mitochondrial Dysfunction, INS-1 Cell Apoptosis, and Increased Sensitivity to Ceramide-, but Not to High Glucose-induced Cell Death*

M. Byrne, H. Düssmann, D. Kögel, 2002, The Journal of Biological Chemistry.

Single-cell quantification of Bax activation and mathematical modelling suggest pore formation on minimal mitochondrial Bax accumulation

M. Rehm, H. Düssmann, C. Concannon, 2010, Cell Death and Differentiation.

Versatile Conjugated Polymer Nanoparticles for High-Resolution O2 Imaging in Cells and 3D Tissue Models.

Ingo Klimant, Shiwen Sun, Heiko Düssmann, 2015, ACS nano.

TOXI-SIM—A simulation tool for the analysis of mitochondrial and plasma membrane potentials

M. Rehm, H. Düssmann, J. Prehn, 2009, Journal of Neuroscience Methods.

Mitochondrial and Plasma Membrane Potential of Cultured Cerebellar Neurons during Glutamate-Induced Necrosis, Apoptosis, and Tolerance

H. Düssmann, J. Prehn, M. Ward, 2007, The Journal of Neuroscience.

BH 3-Only protein bmf is required for the maintenance of glucose homeostasis in an in vivo model of HNF 1 α-MODY diabetes

H. Düssmann, J. Prehn, S. Pfeiffer, 2019 .

BH3-Only protein bmf is required for the maintenance of glucose homeostasis in an in vivo model of HNF1α-MODY diabetes

H. Düssmann, J. Prehn, S. Pfeiffer, 2015, Cell Death Discovery.

BCL2 and BCL(X)L selective inhibitors decrease mitochondrial ATP production in breast cancer cells and are synthetically lethal when combined with 2-deoxy-D-glucose

H. Düssmann, J. Prehn, Federico Lucantoni, 2018, Oncotarget.

TRAIL signaling promotes entosis in colorectal cancer

Seamus J. Martin, D. Longley, H. Düssmann, 2021, The Journal of cell biology.

TRAIL signalling promotes entosis in colorectal cancer

Seamus J. Martin, D. Longley, H. Düssmann, 2020 .

APOPTO-CELL - a simulation tool and interactive database for analyzing cellular susceptibility to apoptosis

Markus Rehm, Jochen H. M. Prehn, Heinrich J. Huber, 2007, Bioinform..

AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy irrespective of expression levels and the subcellular localization of Bcl-xL and Bcl-2 in MCF7 cells.

H. Düssmann, D. Kögel, C. Reimertz, 2016, Biochimica et biophysica acta.

AMPK Preferentially Depresses Retrograde Transport of Axonal Mitochondria during Localized Nutrient Deprivation

H. Düssmann, J. Prehn, N. Connolly, 2020, The Journal of Neuroscience.

AMP‐activated protein kinase (AMPK)–induced preconditioning in primary cortical neurons involves activation of MCL‐1

H. Düssmann, J. Prehn, C. Concannon, 2013, Journal of neurochemistry.

Calpains Are Downstream Effectors of bax-Dependent Excitotoxic Apoptosis

H. Düssmann, J. Prehn, M. Ward, 2012, The Journal of Neuroscience.

AMPK-regulated miRNA-2103 p is activated during ischaemic neuronal injury and modulates PI 3 Kp 70 S 6 K signalling

Stefan J. Haunsberger, N. Plesnila, B. Hennessy, 2021 .

Apoptosis induced by disruption of the actin cytoskeleton is mediated via activation of CD95 (Fas/APO-1)

H. Düssmann, S. Ständer, D. Kulms, 2002, Cell Death and Differentiation.

Effect of TP53 deficiency and KRAS signaling on the bioenergetics of colon cancer cells in response to different substrates: A single cell study

H. Düssmann, J. Prehn, J. Kealey, 2022, Frontiers in Cell and Developmental Biology.

Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8

Maike A. Laussmann, M. Rehm, H. Düssmann, 2011, Cell Death and Differentiation.

Bax Regulates Neuronal Ca2+ Homeostasis

David C. Henshall, Tobias Engel, Heiko Düssmann, 2015, The Journal of Neuroscience.

Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.

H. Düssmann, J. Prehn, K. Umezawa, 2003, Journal of medicinal chemistry.

Real-time single cell analysis of Smac/DIABLO release during apoptosis

Markus Rehm, M. Rehm, H. Düssmann, 2003, The Journal of cell biology.

Single-cell imaging of the heat-shock response in colon cancer cells suggests that magnitude and length rather than time of onset determines resistance to apoptosis

H. Düssmann, C. Concannon, T. Bernaś, 2014, Journal of Cell Science.

Dissipation of Potassium and Proton Gradients Inhibits Mitochondrial Hyperpolarization and Cytochrome c Release during Neural Apoptosis

H. Düssmann, D. Kögel, C. Reimertz, 2001, The Journal of Neuroscience.

Single-cell time-lapse imaging of intracellular O2 in response to metabolic inhibition and mitochondrial cytochrome-c release

H. Düssmann, J. Prehn, D. Papkovsky, 2017, Cell Death & Disease.

Mitochondrial Membrane Permeabilization and Superoxide Production during Apoptosis

M. Rehm, H. Düssmann, D. Kögel, 2003, The Journal of Biological Chemistry.

Outer mitochondrial membrane permeabilization during apoptosis triggers caspase-independent mitochondrial and caspase-dependent plasma membrane potential depolarization: a single-cell analysis

Jochen H M Prehn, Heiko Düssmann, Markus Rehm, 2003, Journal of Cell Science.

ER stress signaling has an activating transcription factor 6α (ATF6)-dependent “off-switch”

H. Düssmann, J. Prehn, C. Concannon, 2018, The Journal of Biological Chemistry.

The death associated protein (DAP) kinase homologue Dlk/ZIP kinase induces p19ARF- and p53-independent apoptosis.

K. Scheidtmann, H. Düssmann, D. Kögel, 2003, European journal of cancer.

Molecular subtype-specific responses of colon cancer cells to the SMAC mimetic Birinapant

D. Longley, H. Düssmann, J. Prehn, 2020, Cell Death & Disease.

Multiple kinetics of mitochondrial cytochrome c release in drug-induced apoptosis.

K. Schulze-Osthoff, H. Düssmann, D. Kögel, 2001, Molecular pharmacology.

Mitochondrial Carrier Homolog 2 Functionally Co-operates With BH3 Interacting-Domain Death Agonist in Promoting Ca2+-Induced Neuronal Injury

H. Düssmann, J. Prehn, N. Niewidok, 2021, Frontiers in Cell and Developmental Biology.

BCL2 and BCL(X)L selective inhibitors decrease mitochondrial ATP production in breast cancer cells and are synthetically lethal when combined with 2-deoxy-D-glucose

H. Düssmann, J. Prehn, Federico Lucantoni, 2018, Oncotarget.

Na+/H+ exchange subtype 1 inhibition during extracellular acidification and hypoxia in glioma cells

D. Leibfritz, H. Düssmann, K. Glunde, 2002, Journal of neurochemistry.

Systems modeling accurately predicts responses to genotoxic agents and their synergism with BCL-2 inhibitors in triple negative breast cancer cells

H. Düssmann, J. Prehn, Federico Lucantoni, 2018, Cell Death & Disease.

ALISSA: an automated live-cell imaging system for signal transduction analyses.

Markus Rehm, Peter Wellstead, Dimitrios Kalamatianos, 2009, BioTechniques.

Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival

H. Düssmann, C. Concannon, J. Prehn, 2015, Cell Death and Differentiation.

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases

David S. Park, S. Lipton, C. Culmsee, 2017, Cell Death & Differentiation.

Bone Morphogenetic Protein 3 Controls Insulin Gene Expression and Is Down-regulated in INS-1 Cells Inducibly Expressing a Hepatocyte Nuclear Factor 1A-Maturity-onset

M. Byrne, H. Düssmann, J. Prehn, 2011 .

Bid and Calpains Cooperate to Trigger Oxaliplatin-Induced Apoptosis of Cervical Carcinoma HeLa Cells

M. Rehm, H. Düssmann, D. Kögel, 2009, Molecular Pharmacology.

Time-lapse imaging of p65 and IκBα translocation kinetics following Ca2+-induced neuronal injury reveals biphasic translocation kinetics in surviving neurons

H. Düssmann, J. Prehn, Hans-Georg König, 2017, Molecular and Cellular Neuroscience.

Single-Cell Imaging of Bioenergetic Responses to Neuronal Excitotoxicity and Oxygen and Glucose Deprivation

H. Düssmann, J. Prehn, H. Huber, 2014, The Journal of Neuroscience.

AMPK‐regulated miRNA‐210‐3p is activated during ischaemic neuronal injury and modulates PI3K‐p70S6K signalling

Stefan J. Haunsberger, N. Plesnila, B. Hennessy, 2021, Journal of neurochemistry.

BCL(X)L and BCL2 increase the metabolic fitness of breast cancer cells: a single-cell imaging study

D. Lambrechts, H. Düssmann, J. Prehn, 2020, Cell Death & Differentiation.

Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM

M. Lamfers, M. Rehm, H. Düssmann, 2021, Cells.

Latrepirdine is a potent activator of AMP-activated protein kinase and reduces neuronal excitability

J. Jordán, H. Düssmann, J. Prehn, 2013, Translational Psychiatry.

The Myosin IXb motor activity targets the myosin IXb RhoGAP domain as cargo to sites of actin polymerization.

H. Düssmann, M. Bähler, Marouan Abouhamed, 2007, Molecular biology of the cell.

Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform

H. Düssmann, J. Prehn, T. Bernaś, 2017, PloS one.

Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer

G. Cagney, A. Letai, M. Hemann, 2021, Science Advances.

Comparative analysis of deeply phenotyped GBM cohorts of ‘short-term’ and ‘long-term’ survivors

D. Lambrechts, M. Lamfers, S. Leenstra, 2023, Journal of Neuro-Oncology.

Dynamics of outer mitochondrial membrane permeabilization during apoptosis

M. Rehm, H. Düssmann, J. Prehn, 2009, Cell Death and Differentiation.

Glucose metabolism determines resistance of cancer cells to bioenergetic crisis after cytochrome-c release

M. Rehm, H. Düssmann, J. Prehn, 2011, Molecular systems biology.

Single-cell imaging of the heat-shock response in colon cancer cells suggests that magnitude and length rather than time of onset determines resistance to apoptosis

H. Düssmann, C. Concannon, T. Bernaś, 2014, Journal of Cell Science.

Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate

H. Düssmann, D. Dávila, C. Concannon, 2012, Cell Death and Differentiation.

Latrepirdine is a potent activator of AMP-activated protein kinase and reduces neuronal excitability

H. Düssmann, B. Baumann, S. M. Kilbride, 2013, Translational Psychiatry.