A. Ashcroft

C. Wild, A. Ashcroft, J. Miller, 2003, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

5-Methylthiopentose: a new substituent on lipoarabinomannan in Mycobacterium tuberculosis.

S. Homans, A. Ashcroft, P. Derrick, 2002, Journal of molecular biology.

Large-Scale Production and Structural and Biophysical Characterizations of the Human Hepatitis B Virus Polymerase

N. Ferguson, A. Ashcroft, Annika Urbanek, 2013, Journal of Virology.

Cytokine Spätzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activation

N. Gay, A. Ashcroft, M. Gangloff, 2013, Proceedings of the National Academy of Sciences.

RNA aptamers for the MS2 bacteriophage coat protein and the wild-type RNA operator have similar solution behaviour.

P. Stockley, A. Ashcroft, N. Stonehouse, 2000, Nucleic acids research.

De novo sequencing of short interfering ribonucleic acids facilitated by use of tandem mass spectrometry with ion mobility spectrometry.

A. Ashcroft, Marco Smith, H. C. Fisher, 2013, Rapid communications in mass spectrometry : RCM.

Does either the gastrointestinal peptide PYY or the neuropeptide NPY bind aluminium?

A. Ashcroft, C. Exley, J. Croom, 2003, Journal of inorganic biochemistry.

Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo

S. Radford, N. Ranson, C. F. van der Walle, 2016, Scientific Reports.

The effect of dimethylbiguanide on thrombin activity, FXIII activation, fibrin polymerization, and fibrin clot formation.

J. Weisel, A. Ashcroft, P. Grant, 2002, Diabetes.

Investigating the structural properties of amyloid-like fibrils formed in vitro from beta2-microglobulin using limited proteolysis and electrospray ionisation mass spectrometry.

S. Radford, A. Ashcroft, N. Thomson, 2006, Rapid communications in mass spectrometry : RCM.

Mass spectrometry-based studies of virus assembly.

A. Ashcroft, 2019, Current opinion in virology.

Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization

M. Luo, N. Ranson, R. Elliott, 2013, Nucleic acids research.

Expanding the Repertoire of Amyloid Polymorphs by Co-polymerization of Related Protein Precursors*

S. Radford, R. Griffin, P. Stockley, 2013, The Journal of Biological Chemistry.

Systematic analysis of the use of amphipathic polymers for studies of outer membrane proteins using mass spectrometry

Thomas G. Watkinson, S. Radford, M. Zoonens, 2015, International journal of mass spectrometry.

Effects of Periplasmic Chaperones and Membrane Thickness on BamA-Catalyzed Outer-Membrane Protein Folding

A. J. Higgins, S. Radford, A. Ashcroft, 2017, Journal of molecular biology.

Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM

A. J. Higgins, S. Radford, N. Ranson, 2016, Nature Communications.

Conformational flexibility within the nascent polypeptide–associated complex enables its interactions with structurally diverse client proteins

M. P. Jackson, S. Radford, A. Ashcroft, 2018, The Journal of Biological Chemistry.

A comparison of the folding characteristics of free and ribosome-tethered polypeptide chains using limited proteolysis and mass spectrometry

S. Radford, A. Ashcroft, J. Reuther, 2015, Protein science : a publication of the Protein Society.

Protein Misfolding and Toxicity in Dialysis-Related Amyloidosis

S. Radford, A. Ashcroft, J. Hodkinson, 2012 .

Skp is a multivalent chaperone of outer membrane proteins

S. Radford, A. Ashcroft, B. Schiffrin, 2016, Nature Structural &Molecular Biology.

An in vivo platform for identifying inhibitors of protein aggregation

M. P. Jackson, S. Radford, A. Ashcroft, 2015, Nature chemical biology.

Continuous-flow fast atom bombardment mass spectrometry.

J. Cottrell, A. Ashcroft, J. Chapman, 1987, Journal of chromatography.

Mass spectrometric methods to analyze the structural organization of macromolecular complexes.

S. Radford, A. Ashcroft, Khadijeh Rajabi, 2015, Methods.

GroEL accelerates the refolding of hen lysozyme without changing its folding mechanism

S. Radford, C. Robinson, A. Ashcroft, 1999, Nature Structural Biology.

Protein and peptide identification: the rôle of mass spectrometry in proteomics.

A. Ashcroft, Alison E Ashcroft, 2003, Natural product reports.

The hepatitis B virus preS1 domain hijacks host trafficking proteins by motif mimicry.

Neil Ferguson, N. Ferguson, Christopher M Johnson, 2013, Nature chemical biology.

HDX-ESI-MS Reveals Enhanced Conformational Dynamics of the Amyloidogenic Protein β2-Microglobulin upon Release from the MHC-1

S. Radford, A. Ashcroft, T. Jahn, 2009, Journal of the American Society for Mass Spectrometry.

The dhnA gene of Escherichia coli encodes a class I fructose bisphosphate aldolase.

A. Ashcroft, G. Howlett, A. Berry, 1998, The Biochemical journal.

A near‐native state on the slow refolding pathway of hen lysozyme

S. Radford, C. Robinson, M. Carey, 2008, Protein science : a publication of the Protein Society.

Assembly Pathway of Hepatitis B Core Virus-like Particles from Genetically Fused Dimers*

D. Rowlands, A. Ashcroft, N. Stonehouse, 2015, The Journal of Biological Chemistry.

PART V. TRH METABOLISM: Comparative Metabolism and Conformation of TRH and Its Analogues

B. Robson, A. Ashcroft, D. J. Ward, 1989 .

Comparative metabolism and conformation of TRH and its analogues.

B. Robson, A. Ashcroft, D. J. Ward, 1989, Annals of the New York Academy of Sciences.

RNA packing specificity and folding during assembly of the bacteriophage MS2.

Ó. Rolfsson, N. Ranson, P. Stockley, 2008, Computational and mathematical methods in medicine.

Advances in ion mobility spectrometry–mass spectrometry reveal key insights into amyloid assembly☆

S. Radford, A. Ashcroft, L. A. Woods, 2013, Biochimica et biophysica acta.

OMS Letter(camera‐ready example)

A. Ashcroft, D. Hutchinson, A. Woolfitt, 1988 .

Analysis of petide digests using high performance liquid chromatography coupled with continuous flow fast atom bombardment mass spectrometry (FAB-MS)

A. Ashcroft, D. Hutchinson, A. Woolfitt, 1987 .

Hemodialysis‐Related Amyloidosis

S. Radford, A. Ashcroft, David P. Smith, 2010 .

Monitoring oligomer formation from self-aggregating amylin peptides using ESI-IMS-MS

S. Radford, A. Ashcroft, S. Harris, 2013, International Journal for Ion Mobility Spectrometry.

ESI-IMS–MS: A method for rapid analysis of protein aggregation and its inhibition by small molecules

S. Radford, A. Ashcroft, R. Foster, 2016, Methods.

Structural Analysis of Bacillus subtilis SPP1 Phage Helicase Loader Protein G39P*

J. Rafferty, J. Alonso, J. Waltho, 2003, The Journal of Biological Chemistry.

Donor-strand exchange in chaperone-assisted pilus assembly revealed in atomic detail by molecular dynamics.

S. Radford, E. Paci, G. Waksman, 2008, Journal of molecular biology.

Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism.

S. Radford, G. Waksman, S. Hultgren, 2006, Molecular cell.

Using ion mobility spectrometry-mass spectrometry to decipher the conformational and assembly characteristics of the hepatitis B capsid protein.

D. Rowlands, A. Ashcroft, N. Stonehouse, 2013, Biophysical journal.

Considering the advantages and pitfalls of the use of isotopically labeled protein standards for accurate protein quantification.

M. Quaglia, A. Ashcroft, G. O’Connor, 2011, Bioanalysis.

N‐terminal acetylation of α‐synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer

Sheena E Radford, J. Baum, A. Ashcroft, 2012, Protein science : a publication of the Protein Society.

ACCELERATEDCOMMUNICATION N-terminal acetylation of a-synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer

S. Radford, J. Baum, A. Ashcroft, 2012 .

Mass spectrometry and the amyloid problem—How far can we go in the gas phase?

A. Ashcroft, 2010, Journal of the American Society for Mass Spectrometry.

Insights into virus capsid assembly from non‐covalent mass spectrometry

P. Stockley, A. Ashcroft, N. Stonehouse, 2008, Mass spectrometry reviews.

Elongated oligomers in β2-microglobulin amyloid assembly revealed by ion mobility spectrometry-mass spectrometry

S. Radford, A. Ashcroft, David P. Smith, 2010, Proceedings of the National Academy of Sciences.

Monitoring Copopulated Conformational States During Protein Folding Events Using Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry

S. Radford, A. Ashcroft, R. Bateman, 2007, Journal of the American Society for Mass Spectrometry.

Separation of β2-microglobulin conformers by high-field asymmetric waveform ion mobility spectrometry (FAIMS) coupled to electrospray ionisation mass spectrometry

S. Radford, A. Ashcroft, A. Borysik, 2004 .

Viral genomic single-stranded RNA directs the pathway toward a T=3 capsid.

Ó. Rolfsson, P. Stockley, A. Ashcroft, 2010, Journal of molecular biology.

Engineering thermal stability in RNA phage capsids via disulphide bonds.

Peter G Stockley, P. Stockley, A. Ashcroft, 2005, Journal of nanoscience and nanotechnology.

Amphipols Outperform Dodecylmaltoside Micelles in Stabilizing Membrane Protein Structure in the Gas Phase

Thomas G. Watkinson, S. Radford, A. Ashcroft, 2014, Analytical chemistry.

Amphipathic Polymers Enable the Study of Functional Membrane Proteins in the Gas Phase

S. Radford, A. Ashcroft, Lindsay Mcmorran, 2012, Analytical chemistry.

Ion Mobility Spectrometry-Mass Spectrometry of Intrinsically Unfolded Proteins: Trying to Put Order into Disorder

A. Ashcroft, S. Warriner, T. Knapman, 2013, Current analytical chemistry.

Comparing Hydrogen Deuterium Exchange and Fast Photochemical Oxidation of Proteins: a Structural Characterisation of Wild-Type and ΔN6 β2-Microglobulin

S. Radford, A. Ashcroft, O. Cornwell, 2018, Journal of The American Society for Mass Spectrometry.

Topological Dissection of the Membrane Transport Protein Mhp1 Derived from Cysteine Accessibility and Mass Spectrometry

S. Radford, J. Gsponer, A. Ashcroft, 2017, Analytical chemistry.

Examination of Ataxin-3 (atx-3) Aggregation by Structural Mass Spectrometry Techniques: A Rationale for Expedited Aggregation upon Polyglutamine (polyQ) Expansion

Sheena E. Radford, Sandra Macedo-Ribeiro, S. Radford, 2015, Molecular & Cellular Proteomics.

Molecular dissection of membrane-transport proteins: mass spectrometry and sequence determination of the galactose-H+ symport protein, GalP, of Escherichia coli and quantitative assay of the incorporation of [ring-2-13C]histidine and (15)NH(3).

A. Ashcroft, P. Henderson, H. Venter, 2002, The Biochemical journal.

The degradation of Abeta(25-35) by the serine protease plasmin is inhibited by aluminium.

A. Ashcroft, C. Exley, T. Kiss, 2002, Journal of Alzheimer's disease : JAD.

Ligand binding to distinct states diverts aggregation of an amyloid-forming protein

S. Radford, S. Homans, A. Ashcroft, 2011, Nature chemical biology.

Hydrogen‐Bonding in 2‐Aminobenzoyl‐α‐chymotrypsin Formed by Acylation of the Enzyme with Isatoic Anhydride: IR and Mass Spectroscopic Studies

C. Wharton, A. Ashcroft, J. J. Goodall, 2002, Chembiochem : a European journal of chemical biology.

A silicon beam-based microcantilever nanoelectrosprayer

L. Buchaillot, B. Legrand, A. Ashcroft, 2007 .

Silicon NANO-ESI Emitters for Mass Spectrometry: A Mixed Micromechanical and Microfluidic Design

B. Legrand, A. Ashcroft, S. Arscott, 2007, TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference.

Insights into the role of the beta-2 microglobulin D-strand in amyloid propensity revealed by mass spectrometry† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c3mb70420c Click here for additional data file.

S. Radford, C. Scarff, A. Ashcroft, 2013, Molecular bioSystems.

The synthesis of anthracyclinones-ii : The synthesis of 7,9-bisdeoxycarminomycinone and -daunomycinone

D. Davies, A. Ashcroft, J. K. Sutherland, 1984 .

Understanding quinone cofactor biogenesis in methylamine dehydrogenase through novel cofactor generation.

C. Wilmot, V. Davidson, A. Ashcroft, 2003, Biochemistry.

RNA-induced conformational changes in a viral coat protein studied by hydrogen/deuterium exchange mass spectrometry.

P. Stockley, A. Ashcroft, N. Stonehouse, 2010, Physical chemistry chemical physics : PCCP.

Control of domain swapping in bovine odorant-binding protein.

Mariella Tegoni, Christian Cambillau, Christel Valencia, 2002, The Biochemical journal.

A comparison of the electromechanical properties of structurally diverse proteins by molecular dynamics simulation

A. Ashcroft, S. Harris, Asmaa A A Elsheshiny, 2014, Journal of biomolecular structure & dynamics.

Direct observation of oligomeric species formed in the early stages of amyloid fibril formation using electrospray ionisation mass spectrometry.

S. Radford, Andrew M. Smith, A. Ashcroft, 2006, Journal of molecular biology.

Co-populated Conformational Ensembles of β2-Microglobulin Uncovered Quantitatively by Electrospray Ionization Mass Spectrometry*

S. Radford, A. Ashcroft, A. Borysik, 2004, Journal of Biological Chemistry.

Determining the topology of virus assembly intermediates using ion mobility spectrometry-mass spectrometry.

P. Stockley, A. Ashcroft, N. Stonehouse, 2010, Rapid communications in mass spectrometry : RCM.

Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients

S. Radford, R. Tuma, P. White, 2020, Nature Communications.

The Role of Chaperone-subunit Usher Domain Interactions in the Mechanism of Bacterial Pilus Biogenesis Revealed by ESI-MS*

S. Radford, G. Waksman, G. Phan, 2012, Molecular & Cellular Proteomics.

Investigation of D76N β2-Microglobulin Using Protein Footprinting and Structural Mass Spectrometry

S. Radford, A. Ashcroft, N. Bond, 2021, Journal of the American Society for Mass Spectrometry.

The role of conformational flexibility in β2-microglobulin amyloid fibril formation at neutral pH

Sheena E Radford, S. Radford, A. Ashcroft, 2012, Rapid communications in mass spectrometry : RCM.

On the quaternary association of the type III secretion system HrcQB-C protein: experimental evidence differentiates among the various oligomerization models.

S. Phillips, M. Kokkinidis, N. M. Glykos, 2009, Journal of structural biology.

Effect of sequence variation on the mechanical response of amyloid fibrils probed by steered molecular dynamics simulation.

S. Radford, A. Ashcroft, S. Harris, 2012, Biophysical journal.

Molecular dynamics simulations of mechanical failure in polymorphic arrangements of amyloid fibrils containing structural defects

S. Radford, A. Ashcroft, S. Harris, 2013, Beilstein journal of nanotechnology.

Validation of IMS-MS as a screening tool to identify type II kinase inhibitors of FGFR1 kinase.

A. Ashcroft, J. Tucker, R. A. Norman, 2021, Rapid communications in mass spectrometry : RCM.

Investigating the Structural Compaction of Biomolecules Upon Transition to the Gas-Phase Using ESI-TWIMS-MS

S. Radford, F. Whelan, A. Ashcroft, 2017, Journal of The American Society for Mass Spectrometry.

Defining topological features of membrane proteins by nanoelectrospray ionisation mass spectrometry.

S. Baldwin, A. Ashcroft, P. Henderson, 2010, Rapid communications in mass spectrometry : RCM.

Reference Protocol to Assess Analytical Performance of Higher Order Structural Analysis Measurements: Results from an Interlaboratory Comparison.

M. Quaglia, R. Davis, B. Wallace, 2021, Analytical Chemistry.

A tale of a tail: Structural insights into the conformational properties of the polyglutamine protein ataxin-3

S. Radford, C. Scarff, A. Ashcroft, 2013, International journal of mass spectrometry.

An Introduction to Mass Spectrometry

A. Ashcroft, 2013 .

Structure and dynamics of oligomeric intermediates in β2-microglobulin self-assembly.

S. Radford, A. Ashcroft, David P. Smith, 2011, Biophysical journal.

N‐terminal acetylation of α‐synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer

J. Baum, A. Ashcroft, G. M. Moriarty, 2012, Protein science : a publication of the Protein Society.

Second Order Rate Constants of Donor-Strand Exchange Reveal Individual Amino Acid Residues Important in Determining the Subunit Specificity of Pilus Biogenesis

S. Radford, G. Waksman, G. Phan, 2011, Journal of the American Society for Mass Spectrometry.

Continuous-flow fast atom bombardment mass spectrometry.

J. Cottrell, A. Ashcroft, J. Chapman, 1987, Journal of chromatography.

Widespread, routine occurrence of pharmaceuticals in sewage effluent, combined sewer overflows and receiving waters.

A. Ashcroft, S. Hughes, L. Brown, 2017, Environmental pollution.

Applications of a continuous flow probe in FAB mass spectrometry

A. Ashcroft, M. Barber, R. S. Brown, 1987 .

A tale of a tail: Structural insights into the conformational properties of the polyglutamine protein ataxin-3

S. Radford, C. Scarff, A. Ashcroft, 2013, International journal of mass spectrometry.