A. K. Todd

发表

A novel series of G-quadruplex ligands with selectivity for HIF-expressing osteosarcoma and renal cancer cell lines.

S. Neidle, Rupesh K. Nanjunda, W. Wilson, 2012, Bioorganic & medicinal chemistry letters.

Sequences in the HSP90 promoter form G-quadruplex structures with selectivity for disubstituted phenyl bis-oxazole derivatives.

Stephan A. Ohnmacht, M. Micco, M. Zloh, 2012, Bioorganic & medicinal chemistry letters.

Highly prevalent putative quadruplex sequence motifs in human DNA

S. Neidle, A. K. Todd, Matthew Johnston, 2005, Nucleic acids research.

Quadruplex DNA: sequence, topology and structure

Sarah W. Burge, G. Parkinson, S. Neidle, 2006, Nucleic acids research.

Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexes.

G. Parkinson, N. Campbell, S. Neidle, 2012, Journal of medicinal chemistry.

Crystal structure of a promoter sequence in the B-raf gene reveals an intertwined dimer quadruplex.

G. Parkinson, M. Zloh, S. Neidle, 2013, Journal of the American Chemical Society.

Mapping the sequences of potential guanine quadruplex motifs

S. Neidle, A. K. Todd, 2011, Nucleic acids research.

The relationship of potential G-quadruplex sequences in cis-upstream regions of the human genome to SP1-binding elements

S. Neidle, A. K. Todd, 2008, Nucleic acids research.

Sequence occurrence and structural uniqueness of a G-quadruplex in the human c-kit promoter

G. Parkinson, S. Neidle, A. K. Todd, 2007, Nucleic acids research.

Targeting pancreatic cancer with a G-quadruplex ligand.

A. Schätzlein, S. Neidle, M. Gunaratnam, 2011, Bioorganic & medicinal chemistry.

Structural characterisation of bisintercalation in higher-order DNA at a junction-like quadruplex.

W. Denny, A. K. Todd, L. P. Wakelin, 2002, Journal of molecular biology.

Synthesis, X-ray crystal structure and reactivity of the polymeric copper(II) dicarboxylic acid complex {Cu2(η1η1μ2-oda)2(py)4(H2O)2}n(odaH2 = octanedioic acid, py = pyridine)

M. Devereux, A. K. Todd, M. Mccann, 1996 .

Synthesis, X-ray crystal structure and catalytic activity of the manganese(II) complex [Mn(bdoa)(H2O)3](bdoaH2 =benzene-1,2-dioxyacetic acid)

M. Devereux, A. K. Todd, M. Mccann, 1996 .

Syntheses and crystal structures of heteroleptic stannylenes and germylenes

A. K. Todd, S. Teixeira, D. Cardin, 1999 .

Preparation of transition metal complexes of bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (C7H9CO2H) and X-ray crystal structure of [Cu2{(±)-endo-μ-O2CC7H9}4 (CH3OH)2]·2CH3OH

A. K. Todd, M. Mccann, C. Cardin, 1997 .

Putative DNA quadruplex formation within the human c-kit oncogene.

Stephen Neidle, Mire Zloh, Alan K Todd, 2005, Journal of the American Chemical Society.

A naphthalene diimide G-quadruplex ligand inhibits cell growth and down-regulates BCL-2 expression in an imatinib-resistant gastrointestinal cancer cell line.

G. Parkinson, S. Neidle, M. Gunaratnam, 2018, Bioorganic & medicinal chemistry.

Bioinformatics approaches to quadruplex sequence location.

Alan K Todd, A. K. Todd, 2007, Methods.

Cluster stability in the analysis of mass cytometry data

R. Melchiotti, A. K. Todd, E. de Rinaldis, 2017, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Small‐molecule G‐quadruplex interactions: Systematic exploration of conformational space using multiple molecular dynamics

J. Platts, S. Neidle, A. K. Todd, 2013, Biopolymers.

Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution.

W. Denny, A. K. Todd, L. P. Wakelin, 1999, Journal of medicinal chemistry.

Molecular Dynamics Studies of the STAT3 Homodimer: DNA Complex: Relationships between STAT3 Mutations and Protein-DNA Recognition

Stephen Neidle, David E. Thurston, Jarmila Husby, 2012, J. Chem. Inf. Model..

The synthesis of dicobalt and dinickel complexes of trimethylsilylethynyl-1, 2-dihydrofullerene; characterisation by n.m.r. and structure of the first acyclic metal fullerene derivative: Molecular structure of [η2-{2-H-1-(Me3SiC ≡ C)-C60}Ni2(η-C5H5)2]

A. K. Todd, M. Pistocchi, D. Cardin, 1997 .

Guanine specific binding at a DNA junction formed by d[CG(5-BrU)ACG](2) with a topoisomerase poison in the presence of Co(2+) ions.

Jerry R. Hobbs, W. Denny, A. K. Todd, 2000, Biochemistry.