J. T. MacDonald

发表

Probing the "dark matter" of protein fold space.

William R Taylor, Inge Jonassen, Siv Midtun Hollup, 2009, Structure.

Development of a Bacillus subtilis cell-free transcription-translation system for prototyping regulatory elements.

P. Freemont, J. T. MacDonald, R. Kelwick, 2016, Metabolic engineering.

A protease-based biosensor for the detection of schistosome cercariae

Richard J. R. Kelwick, P. Freemont, J. T. MacDonald, 2016, Scientific Reports.

Cell-free synthetic biology for in vitro prototype engineering

Paul S. Freemont, James T. MacDonald, Simon J. Moore, 2017, Biochemical Society transactions.

Designing New Proteins

M. Sadowski, J. T. MacDonald, 2011 .

Unfolding crystallins: The destabilizing role of a (cid:1) -hairpin cysteine in (cid:1) B2-crystallin by simulation and experiment

J. Goodfellow, J. T. MacDonald, A. Purkiss, 2005 .

Rapid acquisition and model-based analysis of cell-free transcription–translation reactions from nonmodel bacteria

Paul S. Freemont, Nicolas Kylilis, Karen M. Polizzi, 2018, Proceedings of the National Academy of Sciences.

Analytic Markovian Rates for Generalized Protein Structure Evolution

William R. Taylor, Richard A. Goldstein, Michael I. Sadowski, 2012, PloS one.

gDesigner: computational design of synthetic gRNAs for Cas12a-based transcriptional repression in mammalian cells

P. Freemont, J. T. MacDonald, V. Siciliano, 2022, npj Systems Biology and Applications.

One-pot DNA construction for synthetic biology: the Modular Overlap-Directed Assembly with Linkers (MODAL) strategy

Tom Ellis, Paul S. Freemont, Geoff S. Baldwin, 2013, Nucleic acids research.

Delineation of metabolic gene clusters in plant genomes by chromatin signatures

Paul S. Freemont, Anne Osbourn, Susan J. Rosser, 2016, Nucleic acids research.

R2oDNA designer: computational design of biologically neutral synthetic DNA sequences.

Tom Ellis, Paul S Freemont, Arturo Casini, 2014, ACS synthetic biology.

Unfolding crystallins: The destabilizing role of a β‐hairpin cysteine in βB2‐crystallin by simulation and experiment

Julia M. Goodfellow, James T. MacDonald, Christine Slingsby, 2005 .

De novo backbone scaffolds for protein design

William R Taylor, James T MacDonald, Katarzyna Maksimiak, 2009, Proteins.

Developments in the Tools and Methodologies of Synthetic Biology

Paul Freemont, Richard J. R. Kelwick, Alexander J. Webb, 2014, Front. Bioeng. Biotechnol..

Computational protein design with backbone plasticity

Paul S. Freemont, James T. MacDonald, P. Freemont, 2016, Biochemical Society transactions.

High–quality protein backbone reconstruction from alpha carbons using Gaussian mixture models

James W. Murray, Lawrence A. Kelley, Benjamin L. Moore, 2013, J. Comput. Chem..

Computational design approaches and tools for synthetic biology.

Paul S. Freemont, Richard I. Kitney, Chris P. Barnes, 2011, Integrative biology : quantitative biosciences from nano to macro.

Atomic Structure of Type VI Contractile Sheath from Pseudomonas aeruginosa

P. Freemont, S. Scheres, J. T. MacDonald, 2018, Structure.

Atomic Structure of Type VI Contractile Sheath from Pseudomonas aeruginosa

P. Freemont, S. Scheres, J. T. MacDonald, 2018, Structure.

Structural and Mechanistic Insight into the Listeria monocytogenes Two-enzyme Lipoteichoic Acid Synthesis System

Paul S. Freemont, James T. MacDonald, Andreas Förster, 2014, The Journal of Biological Chemistry.

Synthetic beta-solenoid proteins with the fragment-free computational design of a beta-hairpin extension

James Barber, Paul S Freemont, Sebastian Kraatz, 2016, Proceedings of the National Academy of Sciences.

Comparison of Generalised Born/Surface Area with Periodic Boundary Simulations to Study Protein Unfolding

J. Goodfellow, J. T. MacDonald, A. Purkiss, 2004 .

Computational Sequence Design with R2oDNA Designer.

Velia Siciliano, James T MacDonald, J. T. MacDonald, 2017, Methods in molecular biology.

Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis

P. Freemont, E. Carpenter, J. T. MacDonald, 2012, Proceedings of the National Academy of Sciences.

Prototyping of Bacillus megaterium genetic elements through automated cell-free characterization and Bayesian modelling

Paul S. Freemont, Nicolas Kylilis, Karen M. Polizzi, 2016, bioRxiv.

Cell-Free Protein Synthesis as a Prototyping Platform for Mammalian Synthetic Biology.

Velia Siciliano, David W McClymont, Paul S Freemont, 2020, ACS synthetic biology.

Development of a Bacillus subtilis cell-free transcription-translation system for prototyping regulatory elements.

Richard J. R. Kelwick, P. Freemont, J. T. MacDonald, 2016, Metabolic engineering.

Validating a Coarse-Grained Potential Energy Function through Protein Loop Modelling

Paul S. Freemont, Lawrence A. Kelley, James T. MacDonald, 2013, PloS one.

Cell-free synthetic biology for in vitro prototype engineering

P. Freemont, J. T. MacDonald, S. Moore, 2017, Biochemical Society transactions.