G. Sasnauskas

发表

The Cfr10I restriction enzyme is functional as a tetramer.

C Urbanke, R. Huber, V. Šikšnys, 1999, Journal of molecular biology.

Simultaneous binding of three recognition sites is necessary for a concerted plasmid DNA cleavage by EcoRII restriction endonuclease.

V. Šikšnys, G. Sasnauskas, G. Tamulaitis, 2006, Journal of molecular biology.

How the BfiI restriction enzyme uses one active site to cut two DNA strands

Virginijus Siksnys, Stephen E. Halford, S. Halford, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Novel Subtype of Type IIs Restriction Enzymes

V. Šikšnys, G. Sasnauskas, G. Vilkaitis, 2000, The Journal of Biological Chemistry.

DNA recognition by Arabidopsis transcription factors ABI3 and NGA1

V. Šikšnys, G. Sasnauskas, Kotryna Kauneckaitė, 2018, The FEBS journal.

The link between restriction endonuclease fidelity and oligomeric state: A study with Bse634I

V. Šikšnys, G. Sasnauskas, M. Zaremba, 2012, FEBS letters.

Allosteric communication network in the tetrameric restriction endonuclease Bse634I.

V. Šikšnys, G. Sasnauskas, C. Urbanke, 2006, Journal of molecular biology.

Oligomeric structure diversity within the GIY-YIG nuclease family.

V. Šikšnys, G. Sasnauskas, M. Zakharova, 2009, Journal of molecular biology.

Tetrameric restriction enzymes: expansion to the GIY-YIG nuclease family

G. Gasiunas, V. Šikšnys, G. Sasnauskas, 2007, Nucleic acids research.

Prokaryotic Argonaute from Archaeoglobus fulgidus interacts with DNA as a homodimer

G. Sasnauskas, E. Manakova, Marija Jankunec, 2020, Scientific Reports.

Activity and structure of EcoKMcrA

Shuang-yong Xu, V. Šikšnys, G. Sasnauskas, 2018, Nucleic acids research.

Plasmid DNA cleavage by MunI restriction enzyme: single-turnover and steady-state kinetic analysis.

A. Jeltsch, A. Pingoud, G. Sasnauskas, 1999, Biochemistry.

Recognition of modified cytosine variants by the DNA‐binding domain of methyl‐directed endonuclease McrBC

G. Sasnauskas, E. Manakova, E. Zagorskaitė, 2018, FEBS letters.

DNA-Endonuclease Complex Dynamics by Simultaneous FRET and Fluorophore Intensity in Evanescent Field.

G. Sasnauskas, D. Rutkauskas, Marijonas Tutkus, 2017, Biophysical journal.

Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping

G. Sasnauskas, H. Czapinska, M. Bochtler, 2019, Nucleic acids research.

Chemical Display of Pyrimidine Bases Flipped Out by Modification-Dependent Restriction Endonucleases of MspJI and PvuRts1I Families

G. Sasnauskas, E. Zagorskaitė, 2014, PloS one.

Probing the dynamics of restriction endonuclease NgoMIV‐DNA interaction by single‐molecule FRET

G. Sasnauskas, D. Rutkauskas, Marijonas Tutkus, 2017, Biopolymers.

Degenerate sequence recognition by the monomeric restriction enzyme: single mutation converts BcnI into a strand-specific nicking endonuclease

V. Šikšnys, G. Sasnauskas, G. Tamulaitienė, 2011, Nucleic acids research.

Catalytic activity control of restriction endonuclease--triplex forming oligonucleotide conjugates.

Virginijus Siksnys, V. Šikšnys, G. Sasnauskas, 2012, Bioconjugate chemistry.

A novel mechanism for the scission of double-stranded DNA: BfiI cuts both 3′–5′ and 5′–3′ strands by rotating a single active site

Virginijus Siksnys, Stephen E. Halford, S. Halford, 2010, Nucleic acids research.

A novel mechanism for the scission of double-stranded DNA : BfiI cuts both 3 0 – 5 0 and 5 0 – 3 0 strands by rotating a single active site

Virginijus Siksnys, Stephen E. Halford, S. Halford, 2009 .

The metal-independent type IIs restriction enzyme BfiI is a dimer that binds two DNA sites but has only one catalytic centre.

Virginijus Siksnys, S. Halford, V. Šikšnys, 2003, Journal of molecular biology.

Generation and characterization of new highly thermostable and processive M-MuLV reverse transcriptase variants.

R. Skirgaila, G. Sasnauskas, G. Alzbutas, 2012, Protein engineering, design & selection : PEDS.

Target site cleavage by the monomeric restriction enzyme BcnI requires translocation to a random DNA sequence and a switch in enzyme orientation

V. Šikšnys, G. Sasnauskas, G. Tamulaitis, 2011, Nucleic acids research.

DNA synapsis through transient tetramerization triggers cleavage by Ecl18kI restriction enzyme

Y. Lyubchenko, V. Šikšnys, L. Shlyakhtenko, 2010, Nucleic acids research.

Structure-guided sequence specificity engineering of the modification-dependent restriction endonuclease LpnPI

V. Šikšnys, G. Sasnauskas, Kotryna Kauneckaitė, 2015, Nucleic acids research.

HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation.

Č. Venclovas, V. Šikšnys, G. Sasnauskas, 2020, Molecular cell.

Structural basis of DNA target recognition by the B3 domain of Arabidopsis epigenome reader VAL1

V. Šikšnys, G. Sasnauskas, Kotryna Kauneckaitė, 2018, Nucleic acids research.

Crystal structure of the Bse634I restriction endonuclease: comparison of two enzymes recognizing the same DNA sequence.

R. Huber, V. Repin, V. Šikšnys, 2002, Nucleic acids research.

CRISPR adaptation from a structural perspective.

V. Šikšnys, G. Sasnauskas, 2020, Current opinion in structural biology.

Conversion of the tetrameric restriction endonuclease Bse634I into a dimer: oligomeric structure-stability-function correlations.

V. Šikšnys, G. Sasnauskas, C. Urbanke, 2005, Journal of molecular biology.

TnpB structure reveals minimal functional core of Cas12 nuclease family

Č. Venclovas, G. Montoya, V. Šikšnys, 2023, Nature.

Site-specific DNA transesterification catalyzed by a restriction enzyme

Virginijus Siksnys, S. Halford, V. Šikšnys, 2007, Proceedings of the National Academy of Sciences.

Structure of the tetrameric restriction endonuclease NgoMIV in complex with cleaved DNA

R. Huber, V. Šikšnys, G. Sasnauskas, 2000, Nature Structural Biology.

smFRET Detection of Cis and Trans DNA Interactions by the BfiI Restriction Endonuclease.

Stephen K. Jones, G. Sasnauskas, M. Zaremba, 2023, The journal of physical chemistry. B.

Restriction enzyme Ecl18kI-induced DNA looping dynamics by single-molecule FRET.

V. Šikšnys, G. Sasnauskas, G. Tamulaitis, 2014, The journal of physical chemistry. B.

Domain organization and functional analysis of type IIS restriction endonuclease Eco31I.

A. Janulaitis, G. Sasnauskas, Jolanta Giedriene, 2008, Biochemistry.

Template-directed addition of nucleosides to DNA by the BfiI restriction enzyme

S. Halford, V. Šikšnys, G. Sasnauskas, 2008, Nucleic acids research.

The dynamics of the monomeric restriction endonuclease BcnI during its interaction with DNA

R. Seidel, V. Šikšnys, G. Sasnauskas, 2017, Nucleic acids research.

Structural basis for sequence-specific recognition of guide and target strands by the Archaeoglobus fulgidus Argonaute protein

G. Sasnauskas, S. Gražulis, E. Manakova, 2023, Scientific reports.

UbaLAI is a monomeric Type IIE restriction enzyme

V. Šikšnys, G. Sasnauskas, G. Tamulaitis, 2017, Nucleic acids research.

Structural insight into the specificity of the B3 DNA-binding domains provided by the co-crystal structure of the C-terminal fragment of BfiI restriction enzyme

V. Šikšnys, G. Sasnauskas, S. Gražulis, 2014, Nucleic acids research.

Activation of Thoeris antiviral system via SIR2 effector filament assembly.

R. Sorek, V. Šikšnys, G. Sasnauskas, 2024, Nature.

The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein

Č. Venclovas, G. Sasnauskas, M. Zaremba, 2024, Nucleic acids research.