J. Kobayashi

发表

The Forkhead-associated Domain of NBS1 Is Essential for Nuclear Foci Formation after Irradiation but Not Essential for hRAD50·hMRE11·NBS1 Complex DNA Repair Activity*

D. Delia, H. Tauchi, J. Kobayashi, 2000, The Journal of Biological Chemistry.

DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases.

Benjamin P. C. Chen, J. Kobayashi, H. Yajima, 2009, Journal of molecular biology.

Monoallelic BUB1B mutations and defective mitotic‐spindle checkpoint in seven families with premature chromatid separation (PCS) syndrome

Y. Kajiwara, K. Kurisu, M. Oshimura, 2006, American journal of medical genetics. Part A.

Nijmegen breakage syndrome gene, NBS1, and molecular links to factors for genome stability

Shinya Matsuura, Hiroshi Tauchi, H. Tauchi, 2002, Oncogene.

NBS1 and its functional role in the DNA damage response.

H. Tauchi, A. Antoccia, J. Kobayashi, 2004, DNA repair.

Space Radiation Biology for “Living in Space”

A. Miyawaki, Asako Sakaue-Sawano, Michiyo Suzuki, 2020, BioMed research international.

Diminished or inversed dose-rate effect on clonogenic ability in Ku-deficient rodent cells

Y. Matsumoto, J. Kobayashi, M. Shimada, 2020, Journal of radiation research.

KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR

S. Wakana, T. Hirano, J. Kobayashi, 2015, Nature Communications.

ATM regulates Cdt1 stability during the unperturbed S phase to prevent re-replication

M. Fujita, T. Kiyono, J. Kobayashi, 2013, Cell cycle.

The Potential Roles of DNA-Repair Proteins in Centrosome Maintenance

J. Kobayashi, M. Shimada, Akihiro Kato, 2011 .

Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells

Shunichi Takeda, Shinya Matsuura, Hiroshi Tauchi, 2002, Nature.

Ataxia-Telangiectasia and Nijmegen Breakage Syndrome

J. Kobayashi, 2018, DNA Repair Disorders.

NBS1 is regulated by two kind of mechanisms: ATM-dependent complex formation with MRE11 and RAD50, and cell cycle–dependent degradation of protein

J. Kobayashi, Qiu-Mei Zhang-Akiyama, Hiromi Yanagihara, 2017, Journal of radiation research.

Mutations in the FHA-domain of ectopically expressed NBS1 lead to radiosensitization and to no increase in somatic mutation rates via a partial suppression of homologous recombination

H. Tauchi, J. Kobayashi, K. Komatsu, 2014, Journal of radiation research.

Role of NBS1 in DNA damage response and its relationship with cancer development

J. Kobayashi, Yuichiro Saito, H. Fujimoto, 2013 .

Differential role of repair proteins, BRCA1/NBS1 and Ku70/DNA‐PKcs, in radiation‐induced centrosome overduplication

J. Kobayashi, K. Komatsu, M. Shimada, 2010, Cancer science.

Multiple Roles of NBS1 for Genotoxic and Nongenotoxic Stresses

J. Kobayashi, K. Komatsu, M. Shimada, 2009 .

Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylation

J. Kobayashi, K. Komatsu, R. Ohba, 2010, Molecular Cancer.

NBS1 regulates a novel apoptotic pathway through Bax activation.

H. Tauchi, J. Kobayashi, S. Matsuura, 2008, DNA repair.

NBS1 and MRE11 associate for responses to DNA double-strand breaks

H. Tauchi, A. Antoccia, J. Kobayashi, 2007 .

TopBP1 associates with NBS1 and is involved in homologous recombination repair.

H. Tauchi, J. Kobayashi, K. Morishima, 2007, Biochemical and biophysical research communications.

Nijmegen breakage syndrome and DNA double strand break repair by NBS1 complex.

H. Tauchi, J. Kobayashi, S. Matsuura, 2004, Advances in biophysics.

Histone chaperone FACT regulates homologous recombination by chromatin remodeling through interaction with RNF20

H. Tauchi, J. Kobayashi, K. Komatsu, 2014, Journal of Cell Science.

NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain.

K. Tanimoto, K. Tamai, H. Tauchi, 2002, Current biology : CB.

DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

K. Ishii, S. Akira, T. Kawai, 2013, Proceedings of the National Academy of Sciences.

ATM‐mediated phosphorylation of SOG1 is essential for the DNA damage response in Arabidopsis

H. Maki, M. Umeda, J. Kobayashi, 2013, EMBO reports.

Histone H2AX participates the DNA damage-induced ATM activation through interaction with NBS1.

David J. Chen, Benjamin P. C. Chen, K. Tanimoto, 2009, Biochemical and biophysical research communications.

BRCA1 and CtIP Are Both Required to Recruit Dna2 at Double-Strand Breaks in Homologous Recombination

Nguyen Ngoc Hoa, J. Kobayashi, K. Komatsu, 2015, PloS one.

Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double‐strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell lines

Nguyen Ngoc Hoa, Y. Pommier, J. Kobayashi, 2015, Genes to cells : devoted to molecular & cellular mechanisms.

The proteasome factor Bag101 binds to Rad22 and suppresses homologous recombination

Tomohiro Matsumoto, J. Kobayashi, K. Komatsu, 2013, Scientific Reports.

Hypergonadotropic hypogonadism and hypersegmented neutrophils in a patient with ataxia‐telangiectasia‐like disorder: Potential diagnostic clues?

J. Kobayashi, K. Komatsu, Takeshi Yoshida, 2014, American journal of medical genetics. Part A.

Increased oxidative stress in AOA3 cells disturbs ATM-dependent DNA damage responses.

J. Kobayashi, K. Komatsu, Yuichiro Saito, 2015, Mutation research. Genetic toxicology and environmental mutagenesis.

Wilms’ tumor gene WT1 promotes homologous recombination‐mediated DNA damage repair

E. Morii, J. Kobayashi, K. Komatsu, 2015, Molecular carcinogenesis.

Nucleolar protein nucleolin functions in replication stress–induced DNA damage responses

J. Kobayashi, Fei Qi, Qingmei Meng, 2019, Journal of radiation research.

Severe mitochondrial damage associated with low-dose radiation sensitivity in ATM- and NBS1-deficient cells

J. Kobayashi, K. Komatsu, T. Shimura, 2016, Cell cycle.

SUMO‐targeted ubiquitin ligase RNF4 plays a critical role in preventing chromosome loss

J. Kobayashi, K. Hirota, H. Sasanuma, 2014, Genes to cells : devoted to molecular & cellular mechanisms.

Structural alteration of DNA induced by viral protein R of HIV-1 triggers the DNA damage response

J. Kobayashi, Y. Ishizaka, K. Iijima, 2018, Retrovirology.

The Effect of p53 Status on Radio-Sensitivity of Quiescent Tumor Cell Population Irradiated With γ-Rays at Various Dose Rates

K. Ono, Minoru Suzuki, J. Kobayashi, 2018, Journal of clinical medicine research.

Potential relationship between the biological effects of low-dose irradiation and mitochondrial ROS production

J. Kobayashi, Fei Qi, Kasumi Kawamura, 2018, Journal of radiation research.

Molecular mechanism of the recruitment of NBS1/hMRE11/hRAD50 complex to DNA double-strand breaks: NBS1 binds to gamma-H2AX through FHA/BRCT domain.

J. Kobayashi, Junya Kobayashi, 2004, Journal of radiation research.

RNase MRP Cleaves Pre-tRNASer-Met in the tRNA Maturation Pathway

J. Kobayashi, M. Taoka, K. Hirota, 2014, PloS one.

Generation and characterization of severe combined immunodeficiency rats.

T. Serikawa, J. Kobayashi, K. Komatsu, 2012, Cell reports.

Possible relationship between mitochondrial changes and oxidative stress under low dose-rate irradiation

J. Kobayashi, Qingmei Meng, E. Zaharieva, 2021, Redox report : communications in free radical research.

Ataxia Telangiectasia Mutated (ATM) Is Essential for DNA-PKcs Phosphorylations at the Thr-2609 Cluster upon DNA Double Strand Break*

David J. Chen, B. Chen, M. Löbrich, 2007, Journal of Biological Chemistry.

Inactivation of the Nijmegen breakage syndrome gene leads to excess centrosome duplication via the ATR/BRCA1 pathway.

J. Kobayashi, K. Komatsu, T. Habu, 2009, Cancer research.

Oxidation resistance 1 prevents genome instability through maintenance of G2/M arrest in gamma-ray-irradiated cells

A. Yasui, J. Kobayashi, K. Hashiguchi, 2019, Journal of radiation research.

DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells.

David J. Chen, B. Chen, S. Burma, 2006, DNA repair.

Current topics in DNA double-strand break repair.

K. Miyagawa, Kuniyoshi Iwabuchi, Keiji Suzuki, 2008, Journal of radiation research.

Xray Irradiation Promotes Nerve Growth Factor-induced Neurite Extension in PC12 Cells

J. Kobayashi, T. Umeda, Yoshiko Kobayashi, 2016 .

Radiation-Induced Myofibroblasts Promote Tumor Growth via Mitochondrial ROS–Activated TGFβ Signaling

H. Kawai, K. Kamiya, J. Kobayashi, 2018, Molecular Cancer Research.

RIF1 controls replication initiation and homologous recombination repair in a radiation dose-dependent manner

J. Kobayashi, K. Komatsu, Masato T. Kanemaki, 2020, Journal of Cell Science.

Low Dose-Rate Irradiation of Gamma-Rays-Induced Cytotoxic and Genotoxic Alterations in Peripheral Erythrocytes of p53-Deficient Medaka (Oryzias latipes)

J. Kobayashi, S. Oda, H. Mitani, 2021, Frontiers in Marine Science.

Efficient gene targeting by TAL effector nucleases coinjected with exonucleases in zygotes

T. Serikawa, J. Kobayashi, Takashi Yamamoto, 2013, Scientific Reports.

Regulation of homologous recombination by RNF20-dependent H2B ubiquitination.

H. Tauchi, J. Kobayashi, K. Komatsu, 2011, Molecular cell.

Structural alteration of DNA induced by viral protein R of HIV-1 triggers the DNA damage response

J. Kobayashi, Y. Ishizaka, K. Iijima, 2018, Retrovirology.

WRN participates in translesion synthesis pathway through interaction with NBS1

David J. Chen, B. Chen, K. Tanimoto, 2010, Mechanisms of Ageing and Development.

Cell Cycle Dependence of DNA-dependent Protein Kinase Phosphorylation in Response to DNA Double Strand Breaks*

David J. Chen, B. Chen, D. Chan, 2005, Journal of Biological Chemistry.

FXR1 is a novel MRE11-binding partner and participates in oxidative stress responses

J. Kobayashi, Fei Qi, Qingmei Meng, 2020, Journal of radiation research.

ATM-mediated mitochondrial damage response triggered by nuclear DNA damage in normal human lung fibroblasts

H. Kawai, K. Kamiya, J. Kobayashi, 2017, Cell cycle.

Title Chromatin modification and NBS 1 : Their relationship in DNAdouble-strand break repair

J. Kobayashi, Yuichiro Saito, Hui Zhou, 2018 .

Chromatin modification and NBS1: their relationship in DNA double-strand break repair.

J. Kobayashi, Yuichiro Saito, Hui Zhou, 2015, Genes & genetic systems.

Nucleolin Participates in DNA Double-Strand Break-Induced Damage Response through MDC1-Dependent Pathway

David J. Chen, S. Burma, J. Kobayashi, 2012, PloS one.

An Approach to Elucidate NBS1 Function in DNA Repair Using Frequent Nonsynonymous Polymorphism in Wild Medaka (Oryzias latipes) Populations

J. Kobayashi, S. Oda, H. Mitani, 2017, PloS one.

NBS1 recruits RAD18 via a RAD6-like domain and regulates Pol η-dependent translesion DNA synthesis.

K. Sugasawa, F. Hanaoka, H. Tauchi, 2011, Molecular cell.

Excess processing of oxidative damaged bases causes hypersensitivity to oxidative stress and low dose rate irradiation

J. Kobayashi, A. Yamasaki, M. Takao, 2015, Free radical research.

NBS1 Localizes to γ-H2AX Foci through Interaction with the FHA/BRCT Domain

K. Tanimoto, K. Tamai, H. Tauchi, 2002, Current Biology.

DNA-PK inhibition causes a low level of H2AX phosphorylation and homologous recombination repair in Medaka (Oryzias latipes) cells.

Y. Matsumoto, J. Kobayashi, K. Komatsu, 2012, Biochemical and biophysical research communications.

Possible Role of WRN Protein in Cellular Response Induced by a Little DNA Damage

David J. Chen, J. Kobayashi, K. Komatsu, 2011 .

Induction of Excess Centrosomes in Neural Progenitor Cells during the Development of Radiation-Induced Microcephaly

Tomohiro Matsumoto, J. Kobayashi, K. Komatsu, 2016, PloS one.

A comparison of radiation-induced mitochondrial damage between neural progenitor stem cells and differentiated cells

H. Kawai, K. Kamiya, J. Kobayashi, 2017, Cell cycle.

Nonenzymatic role for WRN in preserving nascent DNA strands after replication stress.

David J. Chen, J. Kobayashi, A. Asaithamby, 2014, Cell reports.

Proceedings of the Frontiers of Retrovirology Conference 2016

Sebastian A. Wagner, R. König, D. Elleder, 2016, Retrovirology.

The ribonuclease domain function is dispensable for SLFN11 to mediate cell fate decision during replication stress response

J. Kobayashi, M. Takata, Fei Qi, 2023, Genes to cells : devoted to molecular & cellular mechanisms.

Hypergonadotropic hypogonadism and hypersegmented neutrophils in a patient with ataxia‐telangiectasia‐like disorder: Potential diagnostic clues?

J. Kobayashi, K. Komatsu, Takeshi Yoshida, 2014, American journal of medical genetics. Part A.

DNA damage signaling guards against perturbation of cyclin D1 expression triggered by low-dose long-term fractionated radiation

J. Kobayashi, K. Komatsu, T. Shimura, 2014, Oncogenesis.