K. Søe

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The Mechanism Switching the Osteoclast From Short to Long Duration Bone Resorption

J. Delaissé, K. Søe, T. L. Andersen, 2021, Frontiers in Cell and Developmental Biology.

Re-thinking the bone remodeling cycle mechanism and the origin of bone loss.

J. Delaissé, K. Søe, T. L. Andersen, 2020, Bone.

Efficient generation of osteoclasts from human induced pluripotent stem cells and functional investigations of lethal CLCN7‐related osteopetrosis

M. Gossen, Z. Izsvák, K. Søe, 2021, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Premature loss of bone remodeling compartment canopies is associated with deficient bone formation: A study of healthy individuals and patients with cushing's syndrome

J. Delaissé, K. Søe, T. L. Andersen, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Pit- and trench-forming osteoclasts: a distinction that matters

M. Ding, J. Delaissé, K. Søe, 2015, Bone Research.

Osteoclast Fusion is Based on Heterogeneity Between Fusion Partners

J. Delaissé, K. Søe, Anne-Sofie Hobolt-Pedersen, 2014, Calcified Tissue International.

Is retention of zoledronic acid onto bone different in multiple myeloma and breast cancer patients with bone metastasis?

T. Plesner, J. Delaissé, K. Søe, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Sugar transporter Slc37a2 regulates bone metabolism via a dynamic tubular lysosomal network in osteoclasts

R. Teasdale, Laila N. Abudulai, K. Søe, 2022, bioRxiv.

Osteoclast Fusion: Physiological Regulation of Multinucleation through Heterogeneity—Potential Implications for Drug Sensitivity

K. Søe, 2020, International journal of molecular sciences.

Zoledronic Acid Is Not Equally Potent on Osteoclasts Generated From Different Individuals

J. Delaissé, K. Søe, J. S. Madsen, 2020, JBMR plus.

GIP receptor reduces osteoclast activity and improves osteoblast survival by activating multiple signaling pathways

M. Rosenkilde, K. Søe, T. L. Andersen, 2022, bioRxiv.

Early‐Onset Osteoporosis: Rare Monogenic Forms Elucidate the Complexity of Disease Pathogenesis Beyond Type I Collagen

O. Mäkitie, M. Zillikens, K. Søe, 2022, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The distribution pattern of critically short telomeres in human osteoarthritic knees

J. Delaissé, K. Søe, T. L. Andersen, 2012, Arthritis Research & Therapy.

Osteoclast Fusion: Time‐Lapse Reveals Involvement of CD47 and Syncytin‐1 at Different Stages of Nuclearity

J. Delaissé, K. Søe, A. Møller, 2016, Journal of cellular physiology.

The elementary fusion modalities of osteoclasts.

J. Delaissé, K. Søe, Anne-Sofie Hobolt-Pedersen, 2015, Bone.

Osteoclasts’ Ability to Generate Trenches Rather Than Pits Depends on High Levels of Active Cathepsin K and Efficient Clearance of Resorption Products

J. Delaissé, K. Søe, D. C. Pirapaharan, 2020, International journal of molecular sciences.

Time-lapse reveals that osteoclasts can move across the bone surface while resorbing

J. Delaissé, K. Søe, 2017, Journal of Cell Science.

Septins are critical regulators of osteoclastic bone resorption

E. Füchtbauer, F. Pedersen, J. Delaissé, 2018, Scientific Reports.

Pit- and trenchforming osteclasts a distinction that matters

M. Ding, J. Delaissé, K. Søe, 2015 .

Human topoisomerase I cleavage complexes are repaired by a p53-stimulated recombination-like reaction in vitro.

F. Grosse, K. Søe, Holger Stephan, 2002, Nucleic acids research.

The tumor suppressor protein p53 stimulates the formation of the human topoisomerase I double cleavage complex in vitro

F. Grosse, K. Søe, B. Schlott, 2002, Oncogene.

Functional Heterogeneity Within Osteoclast Populations—a Critical Review of Four Key Publications that May Change the Paradigm of Osteoclasts

K. Søe, Megan M Weivoda, Megan M. Weivoda, 2022, Current Osteoporosis Reports.

Steering the osteoclast through the demineralization-collagenolysis balance.

J. Delaissé, K. Søe, D. Merrild, 2013, Bone.

Involvement of human endogenous retroviral syncytin-1 in human osteoclast fusion.

J. Delaissé, K. Søe, T. L. Andersen, 2011, Bone.

Glucocorticoid-Induced Changes in the Geometry of Osteoclast Resorption Cavities Affect Trabecular Bone Stiffness

G. V. van Lenthe, J. Delaissé, K. Søe, 2013, Calcified Tissue International.

Coordination of Fusion and Trafficking of Pre-osteoclasts at the Marrow–Bone Interface

J. Delaissé, K. Søe, T. L. Andersen, 2019, Calcified Tissue International.

A phase II clinical trial does not show that high dose simvastatin has beneficial effect on markers of bone turnover in multiple myeloma

T. Plesner, J. Delaissé, K. Søe, 2009, Hematological oncology.

Catabolic activity of osteoblast lineage cells contributes to osteoclastic bone resorption in vitro

J. Delaissé, K. Søe, T. L. Andersen, 2019, Journal of Cell Science.

A novel approach to inhibit bone resorption: exosite inhibitors against cathepsin K

J. Delaissé, K. Søe, D. Brömme, 2016, British journal of pharmacology.

A Mild Inhibition of Cathepsin K Paradoxically Stimulates the Resorptive Activity of Osteoclasts in Culture

J. Delaissé, K. Søe, D. Brömme, 2018, Calcified Tissue International.

An Ectosteric Inhibitor of Cathepsin K Inhibits Bone Resorption in Ovariectomized Mice

J. Delaissé, K. Søe, D. Brömme, 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Glucocorticoids maintain human osteoclasts in the active mode of their resorption cycle

J. Delaissé, K. Søe, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Potential of Resveratrol Analogues as Antagonists of Osteoclasts and Promoters of Osteoblasts

T. Plesner, J. Delaissé, K. Søe, 2010, Calcified Tissue International.

The “GEnomics of Musculo Skeletal Traits TranslatiOnal NEtwork”: Origins, Rationale, Organization, and Prospects

F. Rivadeneira, C. Ohlsson, M. Brandi, 2021, Frontiers in Endocrinology.

Perspective of the GEMSTONE Consortium on Current and Future Approaches to Functional Validation for Skeletal Genetic Disease Using Cellular, Molecular and Animal-Modeling Techniques

S. Reppe, F. Rivadeneira, K. Søe, 2021, Frontiers in Endocrinology.

A metastasis-on-a-chip approach to explore the sympathetic modulation of breast cancer bone metastasis

K. Søe, M. Lamghari, E. Neto, 2022, Materials today. Bio.

A human topoisomerase I cleavage complex is recognized by an additional human topisomerase I molecule in vitro.

G. Dianov, F. Grosse, V. Bohr, 2001, Nucleic acids research.

Coupling of Bone Resorption and Formation in Real Time: New Knowledge Gained From Human Haversian BMUs

J. Delaissé, K. Søe, T. L. Andersen, 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Myeloma cell‐induced disruption of bone remodelling compartments leads to osteolytic lesions and generation of osteoclast‐myeloma hybrid cells

T. Plesner, J. Delaissé, K. Søe, 2010, British journal of haematology.

Sugar transporter Slc37a2 regulates bone metabolism in mice via a tubular lysosomal network in osteoclasts

R. Teasdale, Laila N. Abudulai, H. Takayanagi, 2023, Nature Communications.

Osteoclast Fusion is Based on Heterogeneity Between Fusion Partners

J. Delaissé, K. Søe, Anne-Sofie Hobolt-Pedersen, 2014, Calcified Tissue International.

Aging and menopause reprogram osteoclast precursors for aggressive bone resorption

J. Delaissé, K. Søe, S. Rogatto, 2019, Bone Research.

Osteoclast formation at the bone marrow/bone surface interface: Importance of structural elements, matrix, and intercellular communication.

J. Delaissé, K. Søe, Xenia G. Borggaard, 2020, Seminars in cell & developmental biology.

Role of Human Topoisomerase I in DNA Repair and Apoptosis

F. Grosse, K. Søe, A. Rockstroh, 2005 .