Lakshman Segar

发表

AdipoRon, an adiponectin receptor agonist, attenuates PDGF‐induced VSMC proliferation through inhibition of mTOR signaling independent of AMPK: Implications toward suppression of neointimal hyperplasia

Arwa Fairaq, Noha M. Shawky, Islam Osman, 2017, Pharmacological research.

Sulforaphane inhibits platelet‐derived growth factor‐induced vascular smooth muscle cell proliferation by targeting mTOR/p70S6kinase signaling independent of Nrf2 activation

Noha M. Shawky, Lakshman Segar, 2017, Pharmacological research.

Sulforaphane improves dysregulated metabolic profile and inhibits leptin-induced VSMC proliferation: Implications toward suppression of neointima formation after arterial injury in western diet-fed obese mice.

Noha M. Shawky, Prahalathan Pichavaram, Lakshman Segar, 2016, The Journal of nutritional biochemistry.

Vascular Protection with Dipeptidyl Peptidase‐IV inhibitors in Diabetes: Experimental and Clinical Therapeutics

Lakshman Segar, S. Fagan, D. May, 2015, Pharmacotherapy.

Pioglitazone Attenuates Injury-Induced Neointima Formation in Mouse Femoral Artery Partially through the Activation of AMP-Activated Protein Kinase

Arwa Fairaq, Islam Osman, Lakshman Segar, 2017, Pharmacology.

Sulforaphane improves leptin responsiveness in high‐fat high‐sucrose diet‐fed obese mice

Noha M. Shawky, Lakshman Segar, 2018, European journal of pharmacology.

Leptin treatment inhibits the progression of atherosclerosis by attenuating hypercholesterolemia in type 1 diabetic Ins2(+/Akita):apoE(-/-) mice.

Lakshman Segar, J. Jun, R. Pyla, 2012, Atherosclerosis.

Alcohol‐induced ketonemia is associated with lowering of blood glucose, downregulation of gluconeogenic genes, and depletion of hepatic glycogen in type 2 diabetic db/db mice

Noha M. Shawky, Lakshman Segar, M. Thangaraju, 2019, Biochemical pharmacology.

Spontaneously diabetic Ins2(+/Akita):apoE-deficient mice exhibit exaggerated hypercholesterolemia and atherosclerosis.

Lakshman Segar, J. Jun, Zhexi Ma, 2011, American journal of physiology. Endocrinology and metabolism.

Letter to the Editor: Comment on "SGLT2 inhibitors may predispose to ketoacidosis" by Taylor S.I., et al.

Lakshman Segar, 2016, The Journal of clinical endocrinology and metabolism.

Akt1 Mediates α-Smooth Muscle Actin Expression and Myofibroblast Differentiation via Myocardin and Serum Response Factor*

Lakshman Segar, A. Goc, P. R. Somanath, 2013, The Journal of Biological Chemistry.

Response Factor Differentiation via Myocardin and Serum Expression and Myofibroblast -Smooth Muscle Actin α Akt1 Mediates

Lakshman Segar, A. Goc, P. R. Somanath, 2013 .

SGLT2 inhibitors and metformin: Dual antihyperglycemic therapy and the risk of metabolic acidosis in type 2 diabetes

Lakshman Segar, K. Donnan, 2019, European journal of pharmacology.

skeletal muscle Historical Perspectives: Plasticity of mammalian

Lakshman Segar, B. Jasmin, D. Pette, 2015 .

Imatinib improves insulin resistance and inhibits injury-induced neointimal hyperplasia in high fat diet-fed mice.

Noha M. Shawky, Prahalathan Pichavaram, Lakshman Segar, 2020, European journal of pharmacology.

Altered energy state reversibly controls smooth muscle contractile function in human saphenous vein during acute hypoxia-reoxygenation: Role of glycogen, AMP-activated protein kinase, and insulin-independent glucose uptake.

Arwa Fairaq, Prahalathan Pichavaram, Lakshman Segar, 2015, Biochemical pharmacology.

Pioglitazone, a PPARγ agonist, attenuates PDGF-induced vascular smooth muscle cell proliferation through AMPK-dependent and AMPK-independent inhibition of mTOR/p70S6K and ERK signaling.

Islam Osman, Lakshman Segar, 2016, Biochemical pharmacology.

Expression of conventional and novel glucose transporters, GLUT1, -9, -10, and -12, in vascular smooth muscle cells.

Lakshman Segar, J. Jun, R. Pyla, 2013, American journal of physiology. Cell physiology.

PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates.

Yan Zhao, Lakshman Segar, P. McNulty, 2011, American journal of physiology. Cell physiology.

Metformin exaggerates phenylephrine-induced AMPK phosphorylation independent of CaMKKβ and attenuates contractile response in endothelium-denuded rat aorta.

Islam Osman, Prahalathan Pichavaram, Lakshman Segar, 2014, Biochemical pharmacology.

High fructose-mediated attenuation of insulin receptor signaling does not affect PDGF-induced proliferative signaling in vascular smooth muscle cells.

V. Ganapathy, Islam Osman, Lakshman Segar, 2016, European journal of pharmacology.

AICAR promotes endothelium-independent vasorelaxation by activating AMP-activated protein kinase via increased ZMP and decreased ATP/ADP ratio in aortic smooth muscle

Lakshman Segar, R. Pyla, T. Hartney, 2022, Journal of basic and clinical physiology and pharmacology.

PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates.

Yan Zhao, Lakshman Segar, P. McNulty, 2011, American journal of physiology. Cell physiology.

Pioglitazone, a PPARγ agonist, attenuates PDGF-induced vascular smooth muscle cell proliferation through AMPK-dependent and AMPK-independent inhibition of mTOR/p70S6K and ERK signaling.

Islam Osman, Lakshman Segar, 2016, Biochemical pharmacology.