V. Macrae

发表

Skeletal energy homeostasis: a paradigm of endocrine discovery.

K. Suchacki, F. Roberts, Andrea Lovdel, 2017, The Journal of endocrinology.

Gene expression in the cardiovascular system of the domestic sheep (Ovis aries); a new tool to advance our understanding of cardiovascular disease

D. Hume, V. Macrae, K. Summers, 2020, bioRxiv.

Expression of Calcification and Extracellular Matrix Genes in the Cardiovascular System of the Healthy Domestic Sheep (Ovis aries)

D. Hume, V. Macrae, K. Summers, 2020, Frontiers in Genetics.

Comparative Transcriptomic Profiling and Gene Expression for Myxomatous Mitral Valve Disease in the Dog and Human

V. Macrae, K. Summers, G. Markby, 2017, Veterinary sciences.

Cartilage development and degeneration: a Wnt Wnt situation

C. Farquharson, V. Macrae, K. Staines, 2012, Cell biochemistry and function.

SOCS2 is the critical regulator of GH action in murine growth plate chondrogenesis

C. Farquharson, V. Macrae, C. Pass, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The importance of the SIBLING family of proteins on skeletal mineralisation and bone remodelling.

C. Farquharson, V. Macrae, K. Staines, 2012, The Journal of endocrinology.

Mechanisms and Clinical Consequences of Vascular Calcification

C. Farquharson, V. Macrae, Dongxing Zhu, 2012, Front. Endocrin..

Mechanisms and Clinical Consequences of Vascular Calcification

C. Farquharson, V. Macrae, Dongxing Zhu, 2012, Front. Endocrin..

A novel fluorescein-bisphosphonate based diagnostic tool for the detection of hydroxyapatite in both cell and tissue models

M. Dweck, V. Macrae, F. Nudelman, 2018, Scientific Reports.

PHOSPHO1 is a skeletal regulator of insulin resistance and obesity

J. Millán, K. Suchacki, C. Farquharson, 2020, BMC biology.

The restricted potential for recovery of growth plate chondrogenesis and longitudinal bone growth following exposure to pro-inflammatory cytokines.

C. Farquharson, V. Macrae, S. Ahmed, 2006, The Journal of endocrinology.

Evaluation of canine 2D cell cultures as models of myxomatous mitral valve degeneration

V. Macrae, K. Summers, G. Markby, 2019, PloS one.

Deficiency of the bone mineralization inhibitor NPP1 protects mice against obesity and diabetes

J. Millán, C. Farquharson, V. Macrae, 2014, Disease Models & Mechanisms.

New perspectives on rare connective tissue calcifying diseases.

G. Leftheriotis, V. Macrae, A. Váradi, 2016, Current opinion in pharmacology.

The Appearance and Modulation of Osteocyte Marker Expression during Calcification of Vascular Smooth Muscle Cells

J. Millán, C. Farquharson, V. Macrae, 2011, PloS one.

MOVAS-1 cell line: a new in vitro model of vascular calcification.

C. Patterson, V. Macrae, D. Zhu, 2011, International journal of molecular medicine.

The differentiation and calcification of vascular smooth muscle cells is associated with an osteocyte phenotype

C. Farquharson, V. Macrae, Dongxing Zhu, 2010 .

Inhibition of vascular smooth muscle cell calcification by ATP analogues

J. Millán, V. Macrae, T. Arnett, 2019, Purinergic Signalling.

Inhibition of arterial medial calcification and bone mineralization by extracellular nucleotides: The same functional effect mediated by different cellular mechanisms

J. Millán, V. Macrae, T. Arnett, 2018, Journal of cellular physiology.

Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts

V. Macrae, T. Arnett, I. Orriss, 2019, Experimental cell research.

New insights into NPP1 function: lessons from clinical and animal studies.

V. Macrae, F. Rutsch, C. Huesa, 2012, Bone.

New insights into NPP1 function: lessons from clinical and animal studies.

V. Macrae, F. Rutsch, C. Huesa, 2012, Bone.

Suppressor of cytokine signaling 2 (Socs2) deletion protects bone health of mice with DSS-induced inflammatory bowel disease

C. Farquharson, V. Macrae, S. Ahmed, 2018, Disease Models & Mechanisms.

Ceramide inhibition of chondrocyte proliferation and bone growth is IGF-I independent.

C. Farquharson, V. Macrae, S. Ahmed, 2006, The Journal of endocrinology.

Zinc ameliorates human aortic valve calcification through GPR39 mediated ERK1/2 signaling pathway.

V. Macrae, K. Staines, Pengcheng He, 2020, Cardiovascular research.

IGF-I signalling in bone growth: inhibitory actions of dexamethasone and IL-1beta.

C. Farquharson, V. Macrae, S. Ahmed, 2007, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Regulatory Role of Sex Hormones in Cardiovascular Calcification

V. Macrae, P. Hadoke, Dongxing Zhu, 2021, International journal of molecular sciences.

Osteocalcin Regulates Arterial Calcification Via Altered Wnt Signaling and Glucose Metabolism

D. Newby, F. Roberts, V. Macrae, 2019, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Ex vivo 18F-fluoride uptake and hydroxyapatite deposition in human coronary atherosclerosis

J. Leipsic, M. Dweck, D. Newby, 2020, Scientific Reports.

Cytokine actions in growth disorders associated with pediatric chronic inflammatory diseases (review).

C. Farquharson, V. Macrae, S. Ahmed, 2006, International journal of molecular medicine.

BMP-9 regulates the osteoblastic differentiation and calcification of vascular smooth muscle cells through an ALK1 mediated pathway

C. Farquharson, V. Macrae, C. Shanahan, 2014, Journal of cellular and molecular medicine.

Hdac9 inhibits medial artery calcification through down-regulation of Osterix.

V. Macrae, Pengcheng He, Lei Jiang, 2020, Vascular pharmacology.

Edinburgh Research Explorer Skeletal energy homeostasis

K. Suchacki, F. Roberts, Andrea Lovdel, 2017 .

Myxomatous Degeneration of the Canine Mitral Valve: From Gross Changes to Molecular Events.

V. Macrae, K. Summers, J. Del-Pozo, 2017, Journal of comparative pathology.

Osteoblast‐specific deficiency of ectonucleotide pyrophosphatase or phosphodiesterase‐1 engenders insulin resistance in high‐fat diet fed mice

F. Roberts, C. Farquharson, V. Macrae, 2020, Journal of cellular physiology.

Optimisation of the differing conditions required for bone formation in vitro by primary osteoblasts from mice and rats

V. Macrae, T. Arnett, I. Orriss, 2014, International journal of molecular medicine.

Identification of novel regulators of osteoblast matrix mineralization by time series transcriptional profiling

C. Farquharson, V. Macrae, K. Staines, 2014, Journal of Bone and Mineral Metabolism.

Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair

M. Sharpley, M. Pellegrini, T. Graeber, 2022, The Journal of Clinical Investigation.

Large animal models of cardiovascular disease

C. Whitelaw, V. Macrae, K. Summers, 2016, Cell biochemistry and function.

PALMD regulates aortic valve calcification via altered glycolysis and NF-κB–mediated inflammation

V. Macrae, K. Staines, Pengcheng He, 2022, The Journal of biological chemistry.

Mitochondrial Dysfunction: Cause or Consequence of Vascular Calcification?

V. Macrae, I. Ganley, K. Phadwal, 2021, Frontiers in Cell and Developmental Biology.

ENPP1 in the Regulation of Mineralization and Beyond.

F. Roberts, C. Farquharson, V. Macrae, 2019, Trends in biochemical sciences.

Severe perinatal hydrops fetalis in genome edited pigs with a biallelic five base pair deletion of the Marfan syndrome gene, FBN1

Mary E. B. McCulloch, C. Whitelaw, S. Lillico, 2020, bioRxiv.

Endogenous Calcification Inhibitors in the Prevention of Vascular Calcification: A Consensus Statement From the COST Action EuroSoftCalcNet

G. Leftheriotis, V. Macrae, T. Arányi, 2019, Front. Cardiovasc. Med..

Autophagy as a novel therapeutic target in vascular calcification.

V. Macrae, Du Feng, K. Phadwal, 2020, Pharmacology & therapeutics.

Beyond mineralisation: metabolic functions for matrix mineralisation regulators.

F. Roberts, C. Farquharson, V. Macrae, 2020, The Journal of endocrinology.

Comparative transcriptomic profiling of myxomatous mitral valve disease in the cavalier King Charles spaniel

V. Macrae, K. Summers, G. Markby, 2020, BMC Veterinary Research.

Explorer Increased Linear Bone Growth by GH in the Absence of SOCS 2 is Independent of IGF-1

C. Farquharson, V. Macrae, S. Jasim, 2017 .

Increased linear bone growth by GH in the absence of SOCS2 is independent of IGF‐1

C. Farquharson, V. Macrae, S. Jasim, 2015, Journal of cellular physiology.

Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates

V. Macrae, J. Manson, K. Phadwal, 2018, Scientific Reports.

Mineralisation of collagen rich soft tissues and osteocyte lacunae in Enpp1−/− mice

A. Boyde, J. Millán, V. Macrae, 2014, Bone.

Ablation of the androgen receptor from vascular smooth muscle cells demonstrates a role for testosterone in vascular calcification

Lee B. Smith, D. Newby, V. Macrae, 2016, Scientific Reports.

Bone mineralisation and glucose metabolism

F. Roberts, V. Macrae, 2023, Current opinion in endocrine and metabolic research.

Inflammatory cytokines in juvenile idiopathic arthritis: effects on physical growth and the insulin-like-growth factor axis.

V. Macrae, I. McInnes, J. Gracie, 2008, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

A novel role for the mineralocorticoid receptor in glucocorticoid driven vascular calcification

V. Macrae, P. Hadoke, N. Rashdan, 2016, Vascular pharmacology.

A protective role for FGF-23 in local defence against disrupted arterial wall integrity?

J. Millán, C. Farquharson, V. Macrae, 2013, Molecular and Cellular Endocrinology.

Exploiting novel valve interstitial cell lines to study calcific aortic valve disease

C. Farquharson, V. Macrae, K. Summers, 2017, Molecular medicine reports.

Extragonadal Effects of Follicle-Stimulating Hormone on Osteoporosis and Cardiovascular Disease in Women during Menopausal Transition

V. Macrae, T. Simoncini, Xiaodong Fu, 2018, Trends in Endocrinology & Metabolism.

Bone Research Society, Annual Meeting 2017 Proceedings

P. Tsai, T. Spector, J. Bell, 2018, Journal of musculoskeletal & neuronal interactions.

Disease Severity-Associated Gene Expression in Canine Myxomatous Mitral Valve Disease Is Dominated by TGFβ Signaling

V. Macrae, K. Summers, G. Markby, 2020, Frontiers in Genetics.

Increased PHOSPHO1 and alkaline phosphatase expression during the anabolic bone response to intermittent parathyroid hormone delivery

A. Pitsillides, J. Millán, C. Farquharson, 2022, Cell biochemistry and function.

End stage renal disease‐induced hypercalcemia may promote aortic valve calcification via Annexin VI enrichment of valve interstitial cell derived‐matrix vesicles

M. Dweck, D. Newby, C. Farquharson, 2017, Journal of cellular physiology.

miRNA-221 and miRNA-222 synergistically function to promote vascular calcification

V. Macrae, P. Genever, K. Staines, 2013, Cell biochemistry and function.

The role of cellular senescence during vascular calcification: a key paradigm in aging research.

V. Macrae, N. Mackenzie, V. E. MacRae, 2011, Current aging science.

Effects of etidronate on the Enpp1−/− mouse model of generalized arterial calcification of infancy

J. Millán, V. Macrae, K. Staines, 2015, International journal of molecular medicine.

Isolation and Characterization of Primary Rat Valve Interstitial Cells: A New Model to Study Aortic Valve Calcification

C. Farquharson, V. Macrae, G. Markby, 2017, Journal of visualized experiments : JoVE.

The Role of Pro-Inflammatory Cytokines in Inflammatory Bowel Disease Growth Retardation

V. Macrae, S. C. Wong, S. F. Ahmed, 2006, Journal of pediatric gastroenterology and nutrition.

Edinburgh Research Explorer Endogenous Calcification Inhibitors in the Prevention of Vascular Calcification

G. Leftheriotis, V. Macrae, T. Arányi, 2019 .

Suppressor of cytokine signaling 2 (Socs2) deletion protects bone health of mice with DSS-induced inflammatory bowel disease

C. Farquharson, V. Macrae, S. Ahmed, 2018, Disease Models & Mechanisms.

The pathophysiology of the growth plate in juvenile idiopathic arthritis.

C. Farquharson, V. Macrae, S. Ahmed, 2006, Rheumatology.

Direct stimulation of bone mass by increased GH signalling in the osteoblasts of Socs2−/− mice

C. Farquharson, V. Macrae, S. Ahmed, 2014, The Journal of endocrinology.

The Expression of PHOSPHO1, nSMase2 and TNAP is Coordinately Regulated by Continuous PTH Exposure in Mineralising Osteoblast Cultures

C. Farquharson, V. Macrae, K. Staines, 2016, Calcified Tissue International.

A protective role for FGF-23 in local defence against disrupted arterial wall integrity?

J. Millán, C. Farquharson, V. Macrae, 2013, Molecular and Cellular Endocrinology.

The Appearance and Modulation of Osteocyte Marker Expression during Calcification of Vascular Smooth Muscle Cells

J. Millán, C. Farquharson, V. Macrae, 2011, PloS one.

The importance of the SIBLING family of proteins on skeletal mineralisation and bone remodelling.

C. Farquharson, V. Macrae, K. Staines, 2012, The Journal of endocrinology.

A novel role for the mineralocorticoid receptor in glucocorticoid driven vascular calcification

V. Macrae, P. Hadoke, N. Rashdan, 2016, Vascular pharmacology.

Mechanisms and Clinical Consequences of Vascular Calcification

C. Farquharson, V. Macrae, Dongxing Zhu, 2012, Front. Endocrin..

Editorial: Vascular smooth muscle cell fate and vascular remodeling: Mechanisms, therapeutic targets, and drugs, volume I

V. Macrae, Qilong Wang, X. Dai, 2022, Frontiers in Pharmacology.

Expression of Calcification and Extracellular Matrix Genes in the Cardiovascular System of the Healthy Domestic Sheep (Ovis aries)

V. Macrae, K. Summers, S. Bush, 2020, Frontiers in Genetics.