T. Pulinilkunnil

发表

Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes.

Petra C. Kienesberger, P. Trivedi, J. Bartlett, 2016, Biochimica et biophysica acta.

Role of branched‐chain amino acid–catabolizing enzymes in intertissue signaling, metabolic remodeling, and energy homeostasis

T. Pulinilkunnil, D. Biswas, Luke Duffley, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cardiac complications of congenital disorders of glycosylation (CDG): a systematic review of the literature

T. Pulinilkunnil, J. Jaeken, J. Jaeken, 2017, Journal of Inherited Metabolic Disease.

Cardiac lipoprotein lipase: metabolic basis for diabetic heart disease.

T. Pulinilkunnil, B. Rodrigues, 2006, Cardiovascular research.

Circulating triglyceride lipolysis facilitates lipoprotein lipase translocation from cardiomyocyte to myocardial endothelial lining.

Sanjoy Ghosh, T. Pulinilkunnil, A. Abrahani, 2003, Cardiovascular research.

Short Communication: Ischemia/Reperfusion Tolerance Is Time-of-Day–Dependent: Mediation by the Cardiomyocyte Circadian Clock

J. Dyck, L. Michael, T. Pulinilkunnil, 2009, Circulation research.

AMPK control of myocardial fatty acid metabolism fluctuates with the intensity of insulin-deficient diabetes.

Sanjoy Ghosh, T. Pulinilkunnil, Min Suk Kim, 2007, Journal of molecular and cellular cardiology.

Lysosomal Biology and Function: Modern View of Cellular Debris Bin

P. Trivedi, J. Bartlett, T. Pulinilkunnil, 2020, Cells.

Myocardial Insulin Signaling and Autophagy

P. Trivedi, J. Bartlett, T. Pulinilkunnil, 2018 .

Insulin Signaling in Cardiac Health and Disease

P. Trivedi, J. Bartlett, T. Pulinilkunnil, 2017 .

Autophagic dysregulation in doxorubicin cardiomyopathy.

P. Trivedi, J. Bartlett, T. Pulinilkunnil, 2017, Journal of molecular and cellular cardiology.

Single-dose dexamethasone induces whole-body insulin resistance and alters both cardiac fatty acid and carbohydrate metabolism.

Sanjoy Ghosh, T. Pulinilkunnil, A. Abrahani, 2004, Diabetes.

Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice.

D. Stolz, T. Pulinilkunnil, M. Menke, 2015, Endocrinology.

Myocardial Ketones Metabolism in Heart Failure: Karwi et al. Role of ketone in heart failure.

T. Pulinilkunnil, G. Lopaschuk, D. Biswas, 2020, Journal of cardiac failure.

Brief episode of STZ-induced hyperglycemia produces cardiac abnormalities in rats fed a diet rich in n-6 PUFA.

Sanjoy Ghosh, T. Pulinilkunnil, A. Abrahani, 2004, American journal of physiology. Heart and circulatory physiology.

Cardiac glycogen accumulation after dexamethasone is regulated by AMPK.

T. Pulinilkunnil, P. Puthanveetil, Min Suk Kim, 2008, American journal of physiology. Heart and circulatory physiology.

Loss of function of transcription factor EB remodels lipid metabolism and cell death pathways in the cardiomyocyte.

Petra C. Kienesberger, A. Ballabio, S. Flibotte, 2020, Biochimica et biophysica acta. Molecular basis of disease.

Adverse Outcomes in Obese Cardiac Surgery Patients Correlates With Altered Branched-Chain Amino Acid Catabolism in Adipose Tissue and Heart

Lester J. Pérez, K. Brunt, J. Légaré, 2020, Frontiers in Endocrinology.

Cardiac-specific adipose triglyceride lipase overexpression protects from cardiac steatosis and dilated cardiomyopathy following diet-induced obesity

Petra C. Kienesberger, P. Kienesberger, T. Pulinilkunnil, 2014, International Journal of Obesity.

Myocardial Adipose Triglyceride Lipase Overexpression Protects Diabetic Mice From the Development of Lipotoxic Cardiomyopathy

Petra C. Kienesberger, J. Dyck, R. Zechner, 2013, Diabetes.

Role of dietary fatty acids and acute hyperglycemia in modulating cardiac cell death.

Sanjoy Ghosh, T. Pulinilkunnil, A. Abrahani, 2004, Nutrition.

Silencing branched-chain ketoacid dehydrogenase or treatment with branched-chain ketoacids ex vivo inhibits muscle insulin signaling

Petra C. Kienesberger, P. Kienesberger, T. Pulinilkunnil, 2020, bioRxiv.

Branched-chain ketoacid overload inhibits insulin action in the muscle

Petra C. Kienesberger, P. Kienesberger, T. Pulinilkunnil, 2020, The Journal of Biological Chemistry.

Changes in Circulating Monocyte Subsets (CD16 Expression) and Neutrophil-to-Lymphocyte Ratio Observed in Patients Undergoing Cardiac Surgery

Petra C. Kienesberger, K. Brunt, J. Légaré, 2017, Front. Cardiovasc. Med..

Cardiomyocyte apoptosis induced by short-term diabetes requires mitochondrial GSH depletion.

Sanjoy Ghosh, T. Pulinilkunnil, A. Abrahani, 2005, American journal of physiology. Heart and circulatory physiology.

The role of ubiquitin ligases in cardiac disease.

Petra C. Kienesberger, C. Patterson, P. Kienesberger, 2014, Journal of molecular and cellular cardiology.

The metabolic "switch" AMPK regulates cardiac heparin-releasable lipoprotein lipase.

Sanjoy Ghosh, T. Pulinilkunnil, A. Abrahani, 2005, American journal of physiology. Endocrinology and metabolism.

Evidence for rapid "metabolic switching" through lipoprotein lipase occupation of endothelial-binding sites.

Sanjoy Ghosh, T. Pulinilkunnil, A. Abrahani, 2003, Journal of molecular and cellular cardiology.

Cardiomyocyte specific adipose triglyceride lipase overexpression prevents doxorubicin induced cardiac dysfunction in female mice

Petra C. Kienesberger, J. Dyck, P. Kienesberger, 2013, Heart.

Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy.

Petra C. Kienesberger, P. Trivedi, J. Bartlett, 2016, The Biochemical journal.

Altered cardiac fatty acid composition and utilization following dexamethasone-induced insulin resistance.

Sanjoy Ghosh, T. Pulinilkunnil, A. Abrahani, 2006, American journal of physiology. Endocrinology and metabolism.

Altered Substrate Utilization in the Diabetic Heart: Role of Lipoprotein Lipase

T. Pulinilkunnil, B. Rodrigues, N. Sambandam, 2003 .

Metformin influences cardiomyocyte cell death by pathways that are dependent and independent of caspase-3

T. Pulinilkunnil, A. Abrahani, B. Rodrigues, 2006, Diabetologia.

Adipose Triglyceride Lipase Deficiency Causes Tissue-specific Changes in Insulin Signaling*

Petra C. Kienesberger, J. Flier, R. Zechner, 2009, The Journal of Biological Chemistry.

beta-Agonist stimulation produces changes in cardiac AMPK and coronary lumen LPL only during increased workload.

Sanjoy Ghosh, T. Pulinilkunnil, A. Abrahani, 2005, American journal of physiology. Endocrinology and metabolism.

AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice

Melissa M. Thomas, B. Kemp, T. Pulinilkunnil, 2014, Diabetologia.

Deletion of BCATm increases insulin-stimulated glucose oxidation in the heart.

T. Pulinilkunnil, K. Gopal, G. Lopaschuk, 2021, Metabolism: clinical and experimental.

Myocardial triacylglycerol metabolism.

Petra C. Kienesberger, J. Dyck, P. Kienesberger, 2013, Journal of molecular and cellular cardiology.

Myocardial ATGL Overexpression Decreases the Reliance on Fatty Acid Oxidation and Protects against Pressure Overload-Induced Cardiac Dysfunction

Petra C. Kienesberger, P. Light, J. Dyck, 2011, Molecular and Cellular Biology.

Fibrosis independent atrial fibrillation in older patients is driven by substrate leukocyte infiltration: diagnostic and prognostic implications to patients undergoing cardiac surgery

Petra C. Kienesberger, K. Brunt, J. Légaré, 2019, Journal of Translational Medicine.

Adrenergic Regulation of AMP-activated Protein Kinase in Brown Adipose Tissue in Vivo*

T. Pulinilkunnil, B. Kahn, O. Peroni, 2011, The Journal of Biological Chemistry.

Palmitoyl lysophosphatidylcholine mediated mobilization of LPL to the coronary luminal surface requires PKC activation.

Sanjoy Ghosh, T. Pulinilkunnil, A. Abrahani, 2004, Journal of molecular and cellular cardiology.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Neuronal Protein Tyrosine Phosphatase 1B Deﬁciency Results in Inhibition of Hypothalamic AMPK and Isoform-Speciﬁc Activation of AMPK in Peripheral Tissues (cid:1) †

F. Haj, B. Neel, J. Balschi, 2009 .

Autotaxin Is Regulated by Glucose and Insulin in Adipocytes

P. Kienesberger, T. Pulinilkunnil, E. Kershaw, 2017, Endocrinology.

Ischemia-reperfusion alters cardiac lipoprotein lipase.

T. Pulinilkunnil, F. Wang, P. Puthanveetil, 2010, Biochimica et biophysica acta.

Early structural and metabolic cardiac remodelling in response to inducible adipose triglyceride lipase ablation.

Petra C. Kienesberger, J. Dyck, H. Hackl, 2013, Cardiovascular research.

Whey peptides exacerbate body weight gain and perturb systemic glucose and tissue lipid metabolism in male high-fat fed mice.

Chibuike C. Udenigwe, P. Kienesberger, T. Pulinilkunnil, 2021, Food & Function.

Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity

Petra C. Kienesberger, P. Kienesberger, T. Pulinilkunnil, 2021, Cell death discovery.

Cardiomyocyte-specific ablation of CD36 improves post-ischemic functional recovery.

Petra C. Kienesberger, J. Dyck, P. Kienesberger, 2013, Journal of molecular and cellular cardiology.

AMPK-Dependent Inhibitory Phosphorylation of ACC Is Not Essential for Maintaining Myocardial Fatty Acid Oxidation

J. Dyck, B. Kemp, P. Kienesberger, 2014, Circulation research.

Acute intralipid infusion reduces cardiac luminal lipoprotein lipase but recruits additional enzyme from cardiomyocytes.

Sanjoy Ghosh, T. Pulinilkunnil, A. Abrahani, 2006, Cardiovascular research.

Disrupted branched-chain amino acid catabolism impair cardiac insulin signaling and is associated with adverse cardiometabolic outcomes.

T. Pulinilkunnil, D. Biswas, 2020, Journal of molecular and cellular cardiology.

Loss of transcription factor EB dysregulates the G1/S transition and DNA replication in mammary epithelial cells

Petra C. Kienesberger, P. Kienesberger, T. Pulinilkunnil, 2022, The Journal of biological chemistry.

Lysophosphatidic acid receptor mRNA levels in heart and white adipose tissue are associated with obesity in mice and humans

Petra C. Kienesberger, P. Trivedi, Lester J. Pérez, 2017, PloS one.

sarcoplasmic reticulum: effects of fatiguing activity Glycogen and glycogen phosphorylase associated with

I. Smith, T. Pulinilkunnil, K. Foley, 2015 .

A Lysosome independent role for TFEB in activating DNA repair and inhibiting apoptosis in breast cancer cells.

Petra C. Kienesberger, P. Kienesberger, T. Pulinilkunnil, 2019, The Biochemical journal.

Induction of mitochondrial nitrative damage and cardiac dysfunction by chronic provision of dietary omega-6 polyunsaturated fatty acids.

Sanjoy Ghosh, T. Pulinilkunnil, A. Abrahani, 2006, Free radical biology & medicine.

Skeletal Muscle Triacylglycerol Hydrolysis Does Not Influence Metabolic Complications of Obesity

Petra C. Kienesberger, J. DeLany, D. Stolz, 2013, Diabetes.

The Pathophysiology of Cardiac Hypertrophy and Heart Failure

Avani A. Pendse, J. Schisler, T. Pulinilkunnil, 2014 .

Regulation of autophagy—transcriptional, posttranscriptional, translational, and posttranslational mechanisms

T. Pulinilkunnil, L. Slade, 2022, Autophagy in Health and Disease.

The MiTF/TFE Family of Transcription Factors: Master Regulators of Organelle Signaling, Metabolism, and Stress Adaptation

T. Pulinilkunnil, L. Slade, 2017, Molecular Cancer Research.

Editorial: Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease

P. Kienesberger, T. Pulinilkunnil, J. Nagendran, 2019, Front. Cardiovasc. Med..

Nanoparticle surface-enhanced Raman spectroscopy as a noninvasive, label-free tool to monitor hematological malignancy.

E. Scheme, T. Reiman, A. Phinyomark, 2021, Nanomedicine.

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

Alexander S. Banks, P. Puigserver, L. Alhonen, 2014, Nature.

Validation of optimal reference genes for quantitative real time PCR in muscle and adipose tissue for obesity and diabetes research

Petra C. Kienesberger, P. Trivedi, Lester J. Pérez, 2017, Scientific Reports.

Cardiac triglyceride accumulation following acute lipid excess occurs through activation of a FoxO1-iNOS-CD36 pathway.

T. Pulinilkunnil, P. Puthanveetil, Ying Wang, 2011, Free radical biology & medicine.

AMPK and Metabolic Remodeling in Cardiac Disease

J. Dyck, T. Pulinilkunnil, J. Nagendran, 2012 .

Inhibition of β-Cell Sodium-Calcium Exchange Enhances Glucose-Dependent Elevations in Cytoplasmic Calcium and Insulin Secretion

P. MacDonald, P. Light, X. Dai, 2010, Diabetes.

Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity

Petra C. Kienesberger, P. Kienesberger, T. Pulinilkunnil, 2021, Cell Death Discovery.

Mitochondrial respiratory states and rates

Sharma, Whiejong M. Han, Duchen, 2019 .

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin–sensitizing effects of metformin

J. Dyck, B. Kemp, D. Hardie, 2013, Nature Medicine.

Skeletal muscle ACC2 S212 phosphorylation is not required for the control of fatty acid oxidation during exercise

J. Dyck, B. Kemp, T. Pulinilkunnil, 2015, Physiological reports.

Neuronal Protein Tyrosine Phosphatase 1B Deficiency Results in Inhibition of Hypothalamic AMPK and Isoform-Specific Activation of AMPK in Peripheral Tissues

F. Haj, B. Neel, J. Balschi, 2009, Molecular and Cellular Biology.

Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism[S]

V. Aidinis, P. Trivedi, P. Kienesberger, 2018, Journal of Lipid Research.

cytoskeleton reorganization cardiomyocyte lipoprotein lipase involves actin Lysophosphatidic acid-mediated augmentation of

Sanjoy Ghosh, T. Pulinilkunnil, A. Abrahani, 2016 .

Lysophosphatidic acid-mediated augmentation of cardiomyocyte lipoprotein lipase involves actin cytoskeleton reorganization.

Sanjoy Ghosh, T. Pulinilkunnil, A. Abrahani, 2005, American journal of physiology. Heart and circulatory physiology.

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

B. Lowell, D. Olson, G. Shulman, 2010, Proceedings of the National Academy of Sciences.

Whey Peptides Stimulate Differentiation and Lipid Metabolism in Adipocytes and Ameliorate Lipotoxicity-Induced Insulin Resistance in Muscle Cells

Petra C. Kienesberger, Chibuike C. Udenigwe, P. Kienesberger, 2020, Nutrients.

Serum GDF15, a Promising Biomarker in Obese Patients Undergoing Heart Surgery

K. Brunt, J. Légaré, Ansar Hassan, 2020, Frontiers in Cardiovascular Medicine.

myocytes, impairs acute exercise performance in mice

T. Pulinilkunnil, J. Dubé, M. Basantani, 2015 .

The protonmotive force and respiratory control : Building blocks of mitochondrial physiology Part 1

Tretter, D., M. J., 2017 .

Heparanase protects the heart against chemical or ischemia/reperfusion injury.

C. Nislow, S. Flibotte, T. Pulinilkunnil, 2019, Journal of molecular and cellular cardiology.

Dieldrin Augments mTOR Signaling and Regulates Genes Associated with Cardiovascular Disease in the Adult Zebrafish Heart (Danio rerio)

P. Kienesberger, T. Pulinilkunnil, C. Martyniuk, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Direct Regulation of Myocardial Triglyceride Metabolism by the Cardiomyocyte Circadian Clock*

Petra C. Kienesberger, M. Chandler, J. Dyck, 2009, The Journal of Biological Chemistry.

Impact of Obesity on Postoperative Outcomes following cardiac Surgery (The OPOS study): rationale and design of an investigator-initiated prospective study

Petra C. Kienesberger, K. Brunt, J. Légaré, 2019, BMJ Open.

Increased efflux of glutathione conjugate in acutely diabetic cardiomyocytes.

Sanjoy Ghosh, T. Pulinilkunnil, B. Rodrigues, 2004, Canadian journal of physiology and pharmacology.

Heparanase Overexpression Induces Glucagon Resistance and Protects Animals From Chemically Induced Diabetes

James D. Johnson, C. Nislow, S. Flibotte, 2016, Diabetes.

Distinct Early Signaling Events Resulting From the Expression of the PRKAG2 R302Q Mutant of AMPK Contribute to Increased Myocardial Glycogen

S. Thorn, Anita Y. M. Chan, P. Light, 2009, Circulation. Cardiovascular genetics.

Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease

Petra C. Kienesberger, P. Kienesberger, T. Pulinilkunnil, 2019, Frontiers Research Topics.

Abstract 14197: Cardiac Steatosis Induced by Cardiomyocyte-specific Adipose Triglyceride Lipase Deficiency is Associated with Impaired Oxidative Substrate Metabolism and Hypertrophy

J. Dyck, P. Kienesberger, T. Pulinilkunnil, 2011 .