P. Palese

David E. Swayne, Adolfo García-Sastre, Jeffery K. Taubenberger, 2001, Proceedings of the National Academy of Sciences of the United States of America.

The Ebola Virus VP35 Protein Inhibits Activation of Interferon Regulatory Factor 3

H. Klenk, M. Bray, A. García-Sastre, 2003, Journal of Virology.

Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice

Caitlin E. Mullarkey, Matthew S. Miller, P. Wilson, 2017, Nature Communications.

The 1918 influenza pandemic: lessons from the past raise questions for the future.

P. Palese, J. Steel, 2008 .

Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic

R. Ahmed, P. Palese, M. Oldstone, 2007, Nature Immunology.

A Single Mutation in the PB1-F2 of H5N1 (HK/97) and 1918 Influenza A Viruses Contributes to Increased Virulence

Lucy A. Perrone, T. Tumpey, P. Palese, 2007, PLoS pathogens.

A Single Amino Acid Substitution in 1918 Influenza Virus Hemagglutinin Changes Receptor Binding Specificity

Ian A. Wilson, James Stevens, Jeffery K. Taubenberger, 2005, Journal of Virology.

Toward a universal influenza virus vaccine: prospects and challenges.

P. Palese, Natalie Pica, 2013, Annual review of medicine.

Presentation by a major histocompatibility complex class I molecule of nucleoprotein peptide expressed in two different genes of an influenza virus transfectant

C. Bona, P. Palese, T. Moran, 1995, The Journal of experimental medicine.

Influenza Virus PB1-F2 Protein Induces Cell Death through Mitochondrial ANT3 and VDAC1

Rong Wang, Adolfo García-Sastre, A. García-Sastre, 2005, PLoS pathogens.

Blocking Interhost Transmission of Influenza Virus by Vaccination in the Guinea Pig Model

A. García-Sastre, P. Palese, Anice C. Lowen, 2009, Journal of Virology.

Synthesis and cellular location of the ten influenza polypeptides individually expressed by recombinant vaccinia viruses.

J. Levin, B. Moss, P. Palese, 1987, Virology.

Human antibodies targeting Zika virus NS1 provide protection against disease in a mouse model

R. Hai, V. Simon, P. Palese, 2018, Nature Communications.

Influenza Virus: The Biology of a Changing Virus

P. Palese, S. Mubareka, 2010, Influenza Vaccines for the Future.

Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus

Lucy A. Perrone, A. García-Sastre, T. Tumpey, 2008, Proceedings of the National Academy of Sciences.

Transmission of Influenza Virus via Aerosols and Fomites in the Guinea Pig Model

A. Coates, A. García-Sastre, P. Palese, 2009, The Journal of infectious diseases.

High Temperature (30°C) Blocks Aerosol but Not Contact Transmission of Influenza Virus

John Steel, Samira Mubareka, P. Palese, 2008, Journal of Virology.

Noncumulative sequence changes in the hemagglutinin genes of influenza C virus isolates.

P. Palese, M. Krystal, U. Desselberger, 1985, Virology.

Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice

Caitlin E. Mullarkey, P. Wilson, J. Hamilton, 2017, Nature Communications.

Attenuated Influenza Virus Construct with Enhanced Hemagglutinin Protein Expression

A. García-Sastre, P. Palese, Yi-Ying Chou, 2012, Journal of Virology.

Live Attenuated Influenza Viruses Containing NS1 Truncations as Vaccine Candidates against H5N1 Highly Pathogenic Avian Influenza

John Steel, Matthew Angel, R. Albrecht, 2008, Journal of Virology.

Influenza A Virus PB1-F2 Protein Contributes to Viral Pathogenesis in Mice

P. Palese, M. Ortigoza, Peter Palese, 2006, Journal of Virology.

RNA pattern of ‘Swine’ influenza virus isolated from man is similar to those of other swine influenza viruses

P. Palese, J. Schulman, 1976, Nature.

A Single N66S Mutation in the PB1-F2 Protein of Influenza A Virus Increases Virulence by Inhibiting the Early Interferon Response In Vivo

Michael G. Katze, M. Katze, P. Palese, 2010, Journal of Virology.

Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes

S. Subramaniam, V. Falconieri, P. Palese, 2017, Nature Microbiology.

Measles virus phosphoprotein (P) requires the NH2- and COOH-terminal domains for interactions with the nucleoprotein (N) but only the COOH terminus for interactions with itself.

R. N. Harty, P. Palese, Ronald N Harty, 1995, The Journal of general virology.

Epidemiology of influenza C virus in man: multiple evolutionary lineages and low rate of change.

W. Fitch, P. Palese, D. Buonagurio, 1986, Virology.

Sequential mutations in the NS genes of influenza virus field strains

J. F. Young, P. Palese, M. Krystal, 1983, Journal of virology.

Evolution of human influenza a viruses in nature: Sequential mutations in the genomes of new H1N1 isolates

J. Young, P. Palese, U. Desselberger, 1979, Cell.

Activation of Interferon Regulatory Factor 3 Is Inhibited by the Influenza A Virus NS1 Protein

A. García-Sastre, T. Muster, C. Horvath, 2000, Journal of Virology.

A chimeric hemagglutinin-based universal influenza virus vaccine approach induces broad and long-lasting immunity in a randomized, placebo-controlled phase I trial

D. Bernstein, P. Wilson, E. Walter, 2020, Nature Medicine.

Transmission of Influenza B Viruses in the Guinea Pig

Nicole M. Bouvier, P. Palese, Yi-Ying Chou, 2012, Journal of Virology.

A Two-Amino Acid Change in the Hemagglutinin of the 1918 Influenza Virus Abolishes Transmission

David E. Swayne, N. Cox, A. García-Sastre, 2007, Science.

Rescue of Influenza A Virus from Recombinant DNA

A. García-Sastre, P. Palese, E. Fodor, 1999, Journal of Virology.

Characterization of a Broadly Neutralizing Monoclonal Antibody That Targets the Fusion Domain of Group 2 Influenza A Virus Hemagglutinin

I. Wilson, A. Ward, Paul E. Leon, 2014, Journal of Virology.

A small molecule multi-kinase inhibitor reduces influenza A virus replication by restricting viral RNA synthesis.

P. Palese, L. Martínez-Gil, P. Goff, 2013, Antiviral research.

A Novel Small Molecule Inhibitor of Influenza A Viruses that Targets Polymerase Function and Indirectly Induces Interferon

P. Palese, M. Shaw, L. Martínez-Gil, 2012, PLoS pathogens.

Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo

P. Palese, J. Ravetch, G. Tan, 2014, Nature Medicine.

Broadly Protective Monoclonal Antibodies against H3 Influenza Viruses following Sequential Immunization with Different Hemagglutinins

R. Hai, P. Palese, G. Tan, 2010, PLoS pathogens.

Unraveling the Mystery of Swine Influenza Virus

P. Palese, Taia T. Wang, Peter Palese, 2009, Cell.

A plasmid-based reverse genetics system for influenza A virus

S. Pleschka, A. García-Sastre, P. Palese, 1996, Journal of virology.

Severe Acute Respiratory Syndrome Coronavirus ORF6 Antagonizes STAT1 Function by Sequestering Nuclear Import Factors on the Rough Endoplasmic Reticulum/Golgi Membrane

Ralph S. Baric, R. Baric, M. Heise, 2007, Journal of Virology.

PB1-F2 Expression by the 2009 Pandemic H1N1 Influenza Virus Has Minimal Impact on Virulence in Animal Models

A. García-Sastre, T. Tumpey, R. Hai, 2010, Journal of Virology.

H1 Hemagglutinin Priming Provides Long-Lasting Heterosubtypic Immunity against H5N1 Challenge in the Mouse Model

R. Hai, P. Palese, F. Krammer, 2020, mBio.

The Influenza B Virus Hemagglutinin Head Domain Is Less Tolerant to Transposon Mutagenesis than That of the Influenza A Virus

N. Heaton, P. Palese, Nicholas S. Heaton, 2018, Journal of Virology.

Influenza B virus evolution: co-circulating lineages and comparison of evolutionary pattern with those of influenza A and C viruses.

W. Fitch, M. Yamashita, P. Palese, 1988, Virology.

Newcastle Disease Virus Expressing a Dendritic Cell-Targeted HIV Gag Protein Induces a Potent Gag-Specific Immune Response in Mice

R. Steinman, A. García-Sastre, P. Palese, 2010, Journal of Virology.

Protection of Mice against Lethal Challenge with 2009 H1N1 Influenza A Virus by 1918-Like and Classical Swine H1N1 Based Vaccines

A. García-Sastre, R. Hai, P. Palese, 2010, PLoS pathogens.

Transmission of Pandemic H1N1 Influenza Virus and Impact of Prior Exposure to Seasonal Strains or Interferon Treatment

A. García-Sastre, P. Palese, Anice C. Lowen, 2009, Journal of Virology.

Budding Capability of the Influenza Virus Neuraminidase Can Be Modulated by Tetherin

P. Palese, Fiona Fernandes, Qinshan Gao, 2011, Journal of Virology.

Advances in the development of influenza virus vaccines

P. Palese, F. Krammer, 2015, Nature Reviews Drug Discovery.

Safety and immunogenicity of a ferritin nanoparticle H2 influenza vaccine in healthy adults: a phase 1 trial

J. Mascola, R. Koup, J. Casazza, 2022, Nature Medicine.

Why Do Influenza Virus Subtypes Die Out? A Hypothesis

P. Palese, Taia T. Wang, 2011, mBio.

Influenza Virus NS1 Protein Counteracts PKR-Mediated Inhibition of Replication

Adolfo Garcia-Sastre, H. Pehamberger, A. García-Sastre, 2000, Journal of Virology.

Influenza A and B viruses expressing altered NS1 proteins: A vaccine approach.

A. García-Sastre, T. Muster, P. Palese, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes

S. Subramaniam, V. Falconieri, P. Palese, 2017, Nature Microbiology.

Making Better Influenza Virus Vaccines?

P. Palese, Peter Palese, 2006, Emerging infectious diseases.

Oncolytic Newcastle disease virus for cancer therapy: old challenges and new directions.

P. Palese, D. Zamarin, 2012, Future microbiology.

Therapeutic effects of a fusogenic newcastle disease virus in treating head and neck cancer

R. Wong, P. Palese, Y. Fong, 2011, Head & neck.

Genetic variation of viruses.

P. Palese, B. Roizman, 1980, Annals of the New York Academy of Sciences.

Trivalent NDV-HXP-S vaccine protects against phylogenetically distant SARS-CoV-2 variants of concern in mice

A. García-Sastre, P. Palese, I. González-Domínguez, 2022, bioRxiv.

NPI-1, the human homolog of SRP-1, interacts with influenza virus nucleoprotein.

P. Palese, R. O'neill, P Palese, 1995, Virology.

Enhanced CD8+ T cell response to HIV-1 env by combined immunization with influenza and vaccinia virus recombinants.

A. García-Sastre, P. Palese, M. Esteban, 1999, Vaccine.

Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes

D. Ekiert, A. García-Sastre, R. Hai, 2010, Proceedings of the National Academy of Sciences.

Sequential mutations in hemagglutinins of influenza B virus isolates: definition of antigenic domains.

I. Wilson, J. Skehel, D. Wiley, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Transposon Mutagenesis of the Zika Virus Genome Highlights Regions Essential for RNA Replication and Restricted for Immune Evasion

D. Sachs, P. Palese, Megan C Schwarz, 2017, Journal of Virology.

Induction of Cellular Immune Responses to Simian Immunodeficiency Virus Gag by Two Recombinant Negative-Strand RNA Virus Vectors

A. García-Sastre, P. Palese, J. Imanishi, 2004, Journal of Virology.

Interferon mediated prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine lacking non-structural protein 1

A. García-Sastre, T. Muster, P. Palese, 2021, Scientific Reports.

Prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine.

A. García-Sastre, T. Muster, P. Palese, 2021, Research square.

Prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine

A. García-Sastre, T. Muster, P. Palese, 2021, bioRxiv.

Effects of Influenza A Virus NS1 Protein on Protein Expression: the NS1 Protein Enhances Translation and Is Not Required for Shutoff of Host Protein Synthesis

A. García-Sastre, T. Muster, C. Horvath, 2002, Journal of Virology.

The influenza virus protein PB 1F 2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein VARGA

A. García-Sastre, R. Hai, P. Palese, 2017 .

Replication-Competent Influenza B Reporter Viruses as Tools for Screening Antivirals and Antibodies

N. Heaton, P. Palese, Nicholas S. Heaton, 2015, Journal of Virology.

Induction of Cross-Reactive Antibodies to Novel H7N9 Influenza Virus by Recombinant Newcastle Disease Virus Expressing a North American Lineage H7 Subtype Hemagglutinin

A. García-Sastre, R. Hai, P. Palese, 2013, Journal of Virology.

Chimeric Hemagglutinin Influenza Virus Vaccine Constructs Elicit Broadly Protective Stalk-Specific Antibodies

R. Hai, P. Palese, I. Margine, 2013, Journal of Virology.

Serum- and Glucocorticoid-Regulated Kinase 1 Is Required for Nuclear Export of the Ribonucleoprotein of Influenza A Virus

P. Palese, M. Shaw, S. Stertz, 2013, Journal of Virology.

1976 and 2009 H1N1 influenza virus vaccines boost anti-hemagglutinin stalk antibodies in humans.

Matthew S. Miller, R. Hai, P. Palese, 2013, The Journal of infectious diseases.

A Carboxy-Terminal Trimerization Domain Stabilizes Conformational Epitopes on the Stalk Domain of Soluble Recombinant Hemagglutinin Substrates

Jens C. Krause, P. Palese, I. Margine, 2012, PloS one.

Hemagglutinin Stalk-Reactive Antibodies Are Boosted following Sequential Infection with Seasonal and Pandemic H1N1 Influenza Virus in Mice

R. Hai, P. Palese, F. Krammer, 2012, Journal of Virology.

One influenza virus particle packages eight unique viral RNAs as shown by FISH analysis

T. Ha, P. Palese, Yi-Ying Chou, 2012, Proceedings of the National Academy of Sciences.

The Influenza A Virus PB2, PA, NP, and M Segments Play a Pivotal Role during Genome Packaging

T. Ha, P. Palese, Yi-Ying Chou, 2012, Journal of Virology.

A Pan-H1 Anti-Hemagglutinin Monoclonal Antibody with Potent Broad-Spectrum Efficacy In Vivo

P. Palese, F. Krammer, D. Eggink, 2012, Journal of Virology.

Influenza Viruses Expressing Chimeric Hemagglutinins: Globular Head and Stalk Domains Derived from Different Subtypes

R. Albrecht, R. Hai, P. Palese, 2012, Journal of Virology.

The M Segment of the 2009 New Pandemic H1N1 Influenza Virus Is Critical for Its High Transmission Efficiency in the Guinea Pig Model

R. Albrecht, A. García-Sastre, R. Hai, 2011, Journal of Virology.

A Reassortment-Incompetent Live Attenuated Influenza Virus Vaccine for Protection against Pandemic Virus Strains

A. García-Sastre, R. Hai, P. Palese, 2011, Journal of Virology.

A Nine-Segment Influenza A Virus Carrying Subtype H1 and H3 Hemagglutinins

P. Palese, Anice C. Lowen, Taia T. Wang, 2010, Journal of Virology.

Influenza Virus Vaccine Based on the Conserved Hemagglutinin Stalk Domain

John Steel, Adolfo García-Sastre, A. García-Sastre, 2010, mBio.

Rewiring the RNAs of influenza virus to prevent reassortment

P. Palese, Qinshan Gao, 2009, Proceedings of the National Academy of Sciences.

Influenza A viruses with truncated NS1 as modified live virus vaccines: pilot studies of safety and efficacy in horses.

S. Arkins, A. García-Sastre, P. Palese, 2009, Equine veterinary journal.

Influenza B Virus NS1-Truncated Mutants: Live-Attenuated Vaccine Approach

A. García-Sastre, R. Hai, P. Palese, 2008, Journal of Virology.

A Seven-Segmented Influenza A Virus Expressing the Influenza C Virus Glycoprotein HEF

P. Palese, Qinshan Gao, E. Brydon, 2008, Journal of Virology.

Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies

John Steel, Richard A. Lerner, R. Lerner, 2008, Proceedings of the National Academy of Sciences.

Expression of Transgenes from Newcastle Disease Virus with a Segmented Genome

P. Palese, Man-Seong Park, Qinshan Gao, 2008, Journal of Virology.

Orthomyxoviruses: Molecular Biology

P. Palese, M. Shaw, 2008 .

Highly Conserved Regions of Influenza A Virus Polymerase Gene Segments Are Critical for Efficient Viral RNA Packaging

Arnold J. Levine, R. Rabadán, A. Levine, 2007, Journal of Virology.

A Novel Paramyxovirus?

A. García-Sastre, P. Palese, C. Basler, 2005, Emerging infectious diseases.

Reduced levels of neuraminidase of influenza A viruses correlate with attenuated phenotypes in mice.

A. García-Sastre, P. Palese, E. Fodor, 2000, The Journal of general virology.

Influenza A Virus RNA Polymerase Has the Ability To Stutter at the Polyadenylation Site of a Viral RNA Template during RNA Replication

A. García-Sastre, P. Palese, Hongyong Zheng, 1999, Journal of Virology.

Learning from our foes: a novel vaccine concept for influenza virus.

A. García-Sastre, T. Muster, P. Palese, 1999, Archives of virology. Supplementum.

Evolution of human influenza A viruses in nature: recombination contributes to genetic variation of H1N1 strains.

J. F. Young, P. Palese, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Influenza B and C Virus NEP (NS2) Proteins Possess Nuclear Export Activities

A. García-Sastre, P. Palese, D. Anderson, 2001, Journal of Virology.

Influenza virus hemagglutinin stalk-based antibodies and vaccines.

Florian Krammer, P. Palese, F. Krammer, 2013, Current opinion in virology.

Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19

Christian Drosten, Bernard Roizman, Peter Daszak, 2020, The Lancet.

Cis-acting signals and trans-acting factors involved in influenza virus RNA synthesis.

P. Palese, R. O'neill, 1994, Infectious agents and disease.

Influenza C virus hemagglutinin: comparison with influenza A and B virus hemagglutinins

R. P. Aaronson, P. Palese, M. Krystal, 1984, Journal of virology.

Molecular Epidemiology of Influenza Virus

J. F. Young, P. Palese, 1983 .

Anti-HA Glycoforms Drive B Cell Affinity Selection and Determine Influenza Vaccine Efficacy

R. Ahmed, P. Palese, J. Ravetch, 2015, Cell.

Oseltamivir-Resistant Variants of the 2009 Pandemic H1N1 Influenza A Virus Are Not Attenuated in the Guinea Pig and Ferret Transmission Models

G. Kochs, R. Albrecht, A. García-Sastre, 2010, Journal of Virology.

Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection.

Caitlin E. Mullarkey, F. Ennis, K. Subbarao, 2016, Cell host & microbe.

Recombinant IgA Is Sufficient To Prevent Influenza Virus Transmission in Guinea Pigs

Nicole M. Bouvier, Jens C. Krause, R. Albrecht, 2013, Journal of Virology.

Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N

John Steel, Samira Mubareka, P. Palese, 2009, PLoS pathogens.

High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination

J. Wrammert, R. Ahmed, P. Wilson, 2015, PloS one.

A mosaic hemagglutinin-based influenza virus vaccine candidate protects mice from challenge with divergent H3N2 strains

P. Palese, M. Bailey, F. Krammer, 2019, npj Vaccines.

Immunogenicity of chimeric haemagglutinin-based, universal influenza virus vaccine candidates: interim results of a randomised, placebo-controlled, phase 1 clinical trial

Christopher T. Stamper, D. Bernstein, P. Wilson, 2019, The Lancet. Infectious diseases.

Development of Influenza B Universal Vaccine Candidates Using the “Mosaic” Hemagglutinin Approach

P. Palese, F. Krammer, Megan E. Ermler, 2019, Journal of Virology.

Hemagglutinin Stalk-Based Universal Vaccine Constructs Protect against Group 2 Influenza A Viruses

N. Heaton, P. Wilson, R. Albrecht, 2013, Journal of Virology.

Chimeric Hemagglutinin-Based Influenza Virus Vaccines Induce Protective Stalk-Specific Humoral Immunity and Cellular Responses in Mice

A. García-Sastre, P. Palese, Ronan N. Rouxel, 2019, ImmunoHorizons.

Quantitative Determination of Neuraminidase-Active Foci in Cell Monolayer Cultures Infected with Influenza or Newcastle Disease Virus

P. Palese, G. Bodo, H. Tuppy, 1970, Journal of virology.

Mechanism of attenuation of a chimeric influenza A/B transfectant virus

A. García-Sastre, P. Palese, G. Luo, 1992, Journal of virology.

Viruses and the Innate Immune System

P. Palese, M. Shaw, 2005 .

Discovery of a SARS-CoV-2 Broadly-Acting Neutralizing Antibody with Activity against Omicron and Omicron + R346K Variants

Ashutosh Kumar Singh, H. van Bakel, A. García-Sastre, 2022, bioRxiv.

Defining the antibody cross-reactome against the influenza virus surface glycoproteins

Nicole M. Bouvier, Kimihito Ito, R. Albrecht, 2017, Nature Immunology.

Seroevidence for H5N1 Influenza Infections in Humans: Meta-Analysis

P. Palese, Taia T. Wang, M. Parides, 2012, Science.

Neutralizing Antibodies Against Previously Encountered Influenza Virus Strains Increase over Time: A Longitudinal Analysis

Florian Krammer, Matthew S. Miller, Domenico Tortorella, 2013, Science Translational Medicine.

Pandemic influenza virus vaccines boost hemagglutinin stalk-specific antibody responses in primed adult and pediatric cohorts

R. Albrecht, A. García-Sastre, P. Palese, 2019, npj Vaccines.

An inactivated NDV-HXP-S COVID-19 vaccine elicits a higher proportion of neutralizing antibodies in humans than mRNA vaccination

J. Wrammert, D. Sather, P. Pitisuttithum, 2023, Science Translational Medicine.

Apical Budding of a Recombinant Influenza A Virus Expressing a Hemagglutinin Protein with a Basolateral Localization Signal

A. García-Sastre, P. Palese, E. Rodriguez-Boulan, 2002, Journal of Virology.

In vitro translation of influenza virus messenger RNAs.

P. Palese, M. Richey, 1976, Virology.

Genome Plasticity of Influenza Viruses

P. Palese, S. Stertz, 2012 .

Degradation of single- and double-stranded RNA by frog virus 3.

P. Palese, G. Koch, 1972, Proceedings of the National Academy of Sciences of the United States of America.

RNAs of influenza A, B, and C viruses

P. Palese, M. Ritchey, E. D. Kilbourne, 1976, Journal of virology.

Variation in Influenza Virus Genes

P. Palese, F. Smith, 1989 .

Correlation of High Evolutionary Rate of Influenza A Viruses in Man with High Mutation Rate Measured in Tissue Culture: A Hypothesis

P. Palese, 1988 .

MECHANISMS OF GENETIC VARIATION IN HUMAN INFLUENZA VIRUSES *

J. Young, P. Palese, E. Berkowitz, 1980, Annals of the New York Academy of Sciences.

Overcoming Barriers in the Path to a Universal Influenza Virus Vaccine.

P. Palese, L. Coughlan, Lynda Coughlan, 2018, Cell host & microbe.

Club cells surviving influenza A virus infection induce temporary nonspecific antiviral immunity

Ryan A. Langlois, N. Heaton, D. Sachs, 2016, Proceedings of the National Academy of Sciences.

Antigenic sites in influenza H1 hemagglutinin display species-specific immunodominance

Nicole M. Bouvier, R. Albrecht, V. Simon, 2018, The Journal of clinical investigation.

Long-term survival of influenza virus infected club cells drives immunopathology

N. Heaton, D. Sachs, P. Palese, 2014, The Journal of experimental medicine.

Hemagglutinin-Pseudotyped Green Fluorescent Protein-Expressing Influenza Viruses for the Detection of Influenza Virus Neutralizing Antibodies

John Steel, Thomas M. Moran, A. García-Sastre, 2009, Journal of Virology.

Session Speakers Abstract SESSION I : Viruses : From Environments to Clinics Tuesday , June 19 th , 2018 8 : 30-10 : 00 AM IS 02 Towards a Universal Influenza Virus Vaccine

P. Palese, M. Kikkert, B. Bailey-Elkin, 2018 .

7a Protein of Severe Acute Respiratory Syndrome Coronavirus Inhibits Cellular Protein Synthesis and Activates p38 Mitogen-Activated Protein Kinase

P. Palese, L. Martínez-Sobrido, Sarah A. Kopecky-Bromberg, 2006, Journal of Virology.

Sequential passage of influenza virus in embryonated eggs or tissue culture: emergence of mutants.

P. Palese, C. Brand, 1980, Virology.

Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate

Erin E. H. Tran, O. Kuybeda, A. Bartesaghi, 2016, mBio.

A single-shot adenoviral vaccine provides hemagglutinin stalk-mediated protection against heterosubtypic influenza challenge in mice

P. Palese, F. Krammer, L. Coughlan, 2022, Molecular therapy : the journal of the American Society of Gene Therapy.

Adjuvants and Immunization Strategies to Induce Influenza Virus Hemagglutinin Stalk Antibodies

R. Hai, P. Palese, L. Martínez-Gil, 2013, PloS one.

Influenza virus vectors.

A. García-Sastre, P. Palese, 1995, Biologicals : journal of the International Association of Biological Standardization.

Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS

A. Trkola, H. Katinger, T. Muster, 1994, Journal of virology.

Preexisting human antibodies neutralize recently emerged H7N9 influenza strains.

J. Wrammert, R. Ahmed, Irvin Ho, 2015, The Journal of clinical investigation.

Development of next generation hemagglutinin-based broadly protective influenza virus vaccines.

P. Palese, R. Nachbagauer, Raffael Nachbagauer, 2018, Current opinion in immunology.

Genetics of influenza viruses

P. Palese, Peter Palese, David W. Kingsbury, 1983 .

Transmission of influenza virus in temperate zones is predominantly by aerosol, in the tropics by contact

P. Palese, Anice C. Lowen, 2009, PLoS currents.

Infectious influenza A and B virus variants with long carboxyl terminal deletions in the NS1 polypeptides.

P. Palese, M. Krystal, D. Greenspan, 1987, Virology.

The influenza C virus NS gene: evidence for a spliced mRNA and a second NS gene product (NS2 protein).

P. Palese, P. Graves, S. Nakada, 1986, Virus research.

Complete nucleotide sequence of the influenza C/California/78 virus nucleoprotein gene.

P. Palese, M. Krystal, S. Nakada, 1984, Virus research.

Antigen modifications improve nucleoside-modified mRNA-based influenza virus vaccines in mice

P. Palese, F. Krammer, Ying K. Tam, 2021, Molecular therapy. Methods & clinical development.

PigsVirus Transmission in Guinea Recombinant IgA Is Sufficient To Prevent

Nicole M. Bouvier, Jens C. Krause, R. Albrecht, 2014 .

An influenza hemagglutinin stem nanoparticle vaccine induces cross-group 1 neutralizing antibodies in healthy adults

Carmen M. Graves, J. Mascola, R. Koup, 2023, Science Translational Medicine.

Pandemic influenza virus vaccines boost hemagglutinin stalk-specific antibody responses in primed adult and pediatric cohorts

R. Albrecht, A. García-Sastre, P. Palese, 2019, npj Vaccines.

First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes

Henry A. Utset, Christopher T. Stamper, P. Wilson, 2021, Science Translational Medicine.

Protection from the 2009 H1N1 Pandemic Influenza by an Antibody from Combinatorial Survivor-Based Libraries

John Steel, Richard A. Lerner, Richard Webby, 2010, PLoS pathogens.

Activity of Mouse Interferon in Human Cells

P. Palese, G. Bodo, J. Lindner, 1971, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Selection and identification of influenza virus recombinants of defined genetic composition

P. Palese, J. Schulman, 1976, Journal of virology.

Peering into the Crystal Ball: Influenza Pandemics and Vaccine Efficacy

Matthew S. Miller, P. Palese, M. Miller, 2014, Cell.

Transmission Studies Resume for Avian Flu

Y. Guan, R. Webster, R. Webby, 2013, Science.

Infectious Influenza Viruses from cDNA-Derived RNA: Reverse Genetics

A. García-Sastre, P. Palese, 1993 .

Pause on Avian Flu Transmission Research

John Steel, Paul G. Thomas, Yi Guan, 2012, Science.

Inhibition of Viral Neuraminidase As a New Approach to the Prevention of Influenza

P. Palese, E. D. Kilbourne, J. Schulman, 1975 .

Efficient expression of influenza virus NS1 nonstructural proteins in Escherichia coli.

J. F. Young, P. Palese, M. Rosenberg, 1983, Proceedings of the National Academy of Sciences of the United States of America.

NS1-Truncated Live Attenuated Virus Vaccine Provides Robust Protection to Aged Mice from Viral Challenge

Ryan A. Langlois, Florian Krammer, P. Palese, 2012, Journal of Virology.

Immunodominance of Antigenic Site B in the Hemagglutinin of the Current H3N2 Influenza Virus in Humans and Mice

V. Simon, P. Palese, F. Krammer, 2018, Journal of Virology.

A public broadly neutralizing antibody class targets a membrane-proximal anchor epitope of influenza virus hemagglutinin

Henry A. Utset, Christopher T. Stamper, J. Bloom, 2021, bioRxiv.

Guiding the Immune Response against Influenza Virus Hemagglutinin toward the Conserved Stalk Domain by Hyperglycosylation of the Globular Head Domain

P. Palese, D. Eggink, P. Goff, 2013, Journal of Virology.

Age Dependence and Isotype Specificity of Influenza Virus Hemagglutinin Stalk-Reactive Antibodies in Humans

P. Palese, F. Krammer, M. Cox, 2016, mBio.

The Hemagglutinin Gene of Influenza Viruses

P. Palese, 1978 .

THE NONSTRUCTURAL GENE SEGMENT OF INFLUENZA A VIRUS: EXPRESSION OF NS1 PROTEIN IN MAMMALIAN CELLS; ANALYSIS OF A DELETION MUTANT

H. Maassab, P. Palese, M. Krystal, 1984 .

Influenza Virus Hemagglutinin Stalk-Specific Antibodies in Human Serum are a Surrogate Marker for In Vivo Protection in a Serum Transfer Mouse Challenge Model

P. Palese, R. Cox, K. Brokstad, 2017, mBio.

Expression of antisense RNA fails to inhibit influenza virus replication

P. Palese, M. Krystal, J. Leiter, 1989, Virus Research.

Advances in universal influenza virus vaccine design and antibody mediated therapies based on conserved regions of the hemagglutinin.

P. Palese, J. Steel, F. Krammer, 2015, Current topics in microbiology and immunology.

Bioprocess development for universal influenza vaccines based on inactivated split chimeric and mosaic hemagglutinin viruses

P. Palese, F. Krammer, G. Bajic, 2023, Frontiers in Bioengineering and Biotechnology.

Group 1 and group 2 hemagglutinin stalk antibody response according to age

A. García-Sastre, P. Palese, J. Eiros, 2023, Frontiers in Immunology.

Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface

P. Palese, F. Krammer, Xueyong Zhu, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Molecular weights of RNA segments of influenza A and B viruses.

P. Palese, U. Desselberger, 1978, Virology.

Common Sequence at the 5′ Ends of the Segmented RNA Genomes of Influenza A and B Viruses

B. Moss, P. Palese, M. Ritchey, 1978, Journal of virology.

Polyacrylamide gel electrophoresis of the RNAs of new influenza virus strains: an epidemiological tool.

P. Palese, M. Ritchey, 1977, Developments in biological standardization.

Vaccination with Vesicular Stomatitis Virus-Vectored Chimeric Hemagglutinins Protects Mice against Divergent Influenza Virus Challenge Strains

P. Palese, F. Krammer, J. Rose, 2015, Journal of Virology.

A mosaic hemagglutinin-based influenza virus vaccine candidate protects mice from challenge with divergent H3N2 strains

P. Palese, M. Bailey, F. Krammer, 2019, npj Vaccines.

Influenza C virus RNA 7 codes for a nonstructural protein

P. Palese, M. Krystal, U. Desselberger, 1985, Journal of virology.

Interim safety and immunogenicity results from an NDV-based COVID-19 vaccine phase I trial in Mexico

A. García-Sastre, P. Palese, I. González-Domínguez, 2023, NPJ vaccines.

Emergence and evolution of the 1918, 1957, 1968, and 2009 pandemic virus strains

P. Palese, Taia T. Wang, 2013 .

Rapid RNA sequencing using double-stranded template DNA, SP6 polymerase, and 3'-deoxynucleotide triphosphates.

J. Parvin, P. Palese, F. Smith, 1986, DNA.

128 Toward a Universal Influenza Virus Vaccine

P. Palese, 2012 .

Influenza virus transmission: basic science and implications for the use of antiviral drugs during a pandemic.

P. Palese, Anice C. Lowen, Peter Palese, 2007, Infectious disorders drug targets.

The great influenzaThe epic story of the deadliest plague in history

P. Palese, 2004 .

Influenza A VirusTransfectants withChimeric Hemagglutinins Containing Epitopes fromDifferent Subtypes

C. Bona, P. Palese, T. Moran, 1992 .

Evolutionary Lineages and Molecular Epidemiology of Influenza A, B, and C Viruses

M. Yamashita, P. Palese, 1990 .

The inactivated NDV-HXP-S COVID-19 vaccine induces a significantly higher ratio 1 of neutralizing to non-neutralizing antibodies in humans as compared to mRNA 2 vaccines 3