A. Otto

发表

Purification and proteomics of pathogen-modified vacuoles and membranes

N. Hansmeier, J. Herweg, A. Otto, 2015, Front. Cell. Infect. Microbiol..

Symbiotic Interplay of Fungi, Algae, and Bacteria within the Lung Lichen Lobaria pulmonaria L. Hoffm. as Assessed by State-of-the-Art Metaproteomics.

Jörg Bernhardt, Martin Grube, Stephan Fuchs, 2017, Journal of proteome research.

Metabolic Reprogramming of Clostridioides difficile During the Stationary Phase With the Induction of Toxin Production

A. Otto, D. Becher, D. Jahn, 2018, Front. Microbiol..

Comprehensive spectral library from the pathogenic bacterium Streptococcus pneumoniae with focus on phosphoproteins.

M. Hecker, A. Otto, D. Becher, 2020, Journal of proteome research.

Substrate-Controlled Succession of Marine Bacterioplankton Populations Induced by a Phytoplankton Bloom

R. Amann, Marc Weber, H. Teeling, 2012, Science.

Systems-wide temporal proteomic profiling in glucose-starved Bacillus subtilis

J. Bernhardt, M. Hecker, M. Lalk, 2010, Nature communications.

Functional characterization of polysaccharide utilization loci in the marine Bacteroidetes ‘Gramella forsetii' KT0803

R. Amann, H. Teeling, T. Schweder, 2014, The ISME Journal.

Small cationic antimicrobial peptides delocalize peripheral membrane proteins

H. Sahl, J. Bandow, Ute Krämer, 2014, Proceedings of the National Academy of Sciences.

Protein Enrichment from Highly Dilute Samples with StrataClean.

A. Otto, F. Bonn, 2018, Methods in molecular biology.

An Easy and Fast Protocol for Affinity Bead-Based Protein Enrichment and Storage of Proteome Samples.

A. Otto, D. Becher, F. Bonn, 2017, Methods in enzymology.

A homopolymeric adenosine tract in the promoter region of nspA influences factor H-mediated serum resistance in Neisseria meningitidis

A. Otto, D. Becher, H. Claus, 2019, Scientific Reports.

Monitoring of changes in the membrane proteome during stationary phase adaptation of Bacillus subtilis using in vivo labeling techniques

M. Hecker, A. Teumer, U. Völker, 2008, Proteomics.

Proteomics: From relative to absolute quantification for systems biology approaches

J. Bernhardt, M. Hecker, U. Völker, 2012 .

Towards the entire proteome of the model bacterium Bacillus subtilis by gel-based and gel-free approaches.

Jörg Bernhardt, Sierd Bron, Michael Hecker, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Tryptic shaving of Staphylococcus aureus unveils immunodominant epitopes on the bacterial cell surface.

J. Benschop, J. Bernhardt, M. Hecker, 2020, Journal of proteome research.

A guide through the computational analysis of isotope-labeled mass spectrometry-based quantitative proteomics data: an application study

Hannes Hahne, A. Goesmann, S. Albaum, 2011, Proteome Science.

Identification of new protein-coding genes with a potential role in the virulence of the plant pathogen Xanthomonas euvesicatoria

U. Bonas, A. Otto, D. Becher, 2017, BMC Genomics.

Quantitative proteomics in the field of microbiology

A. Otto, D. Becher, F. Schmidt, 2014, Proteomics.

Impact of Moderate Temperature Changes on Neisseria meningitidis Adhesion Phenotypes and Proteome

A. Otto, D. Becher, U. Vogel, 2016, Infection and Immunity.

Earthworm gene as indicator of bioefficacious cadmium.

A. Otto, F. Wunderlich, H. Schmitt-Wrede, 1996, Biochemical and biophysical research communications.

Comprehensive proteome analysis of Actinoplanes sp. SE50/110 highlighting the location of proteins encoded by the acarbose and the pyochelin biosynthesis gene cluster.

M. Hecker, J. Kalinowski, A. Pühler, 2015, Journal of proteomics.

The Proteomic Response of Bacillus pumilus Cells to Glucose Starvation

M. Hecker, A. Otto, D. Becher, 2018, Proteomics.

Subtractive Interaction Proteomics Reveal a Network of Signaling Pathways Activated by an Oncogenic Transcription Factor in Acute Myeloid Leukemia

A. Otto, K. Heesom, O. Ottmann, 2018, bioRxiv.

Subtractive Interaction Proteomics Reveal a Network of Signaling Pathways Activated by an Oncogenic Transcription Factor in Acute Myeloid Leukemia

A. Otto, D. Becher, K. Heesom, 2018 .

Signatures of cytoplasmic proteins in the exoproteome distinguish community- and hospital-associated methicillin-resistant Staphylococcus aureus USA300 lineages

U. Völker, J. V. van Dijl, A. Otto, 2017, Virulence.

Subtoxic cadmium-concentrations reduce copper-toxicity in the earthworm Enchytraeus buchholzi

A. Otto, F. Wunderlich, J. Willuhn, 1996 .

Quantitative cell surface proteome profiling for SigB-dependent protein expression in the human pathogen Staphylococcus aureus via biotinylation approach.

M. Hecker, A. Otto, D. Becher, 2010, Journal of proteome research.

Functional analysis of novel Rab GTPases identified in the proteome of purified Legionella‐containing vacuoles from macrophages

M. Hecker, A. Otto, D. Becher, 2014, Cellular microbiology.

"Gently rough": the vaccine potential of a Salmonella enterica regulatory lipopolysaccharide mutant.

S. Engelmann, M. Hecker, J. Hacker, 2008, The Journal of infectious diseases.

Characterization of Helicobacter pylori VacA‐containing vacuoles (VCVs), VacA intracellular trafficking and interference with calcium signalling in T lymphocytes

A. Otto, D. Becher, R. Haas, 2015, Cellular microbiology.

Proteomic evidence of methanotrophy in methane‐enriched hypolimnetic lake water

A. Otto, M. Gessner, P. Casper, 2016 .

Evolutionary Events Associated with an Outbreak of Meningococcal Disease in Men Who Have Sex with Men

D. Harmsen, A. Otto, D. Becher, 2016, PloS one.

Proteomic analysis of bacterial (outer) membrane vesicles: progress and clinical potential

A. Otto, D. Becher, T. Kroniger, 2018, Expert review of proteomics.

University of Groningen Penicillin-binding protein folding is dependent on the PrsA peptidyl-prolyl cis-trans isomerase in Bacillus subtilis Hyyrylainen,

O. Kuipers, A. Otto, D. Becher, 2010 .

A Lactococcal Phage Protein Promotes Viral Propagation and Alters the Host Proteomic Response During Infection

Pier-Luc Plante, J. Corbeil, A. Otto, 2020, Viruses.

A Secreted Bacterial Peptidylarginine Deiminase Can Neutralize Human Innate Immune Defenses

J. V. van Dijl, A. Otto, D. Becher, 2018, mBio.

University of Groningen A Secreted Bacterial Peptidylarginine Deiminase Can Neutralize Human Innate Immune Defenses Stobernack,

A. Otto, D. Becher, J. Westra, 2018 .

SppI Forms a Membrane Protein Complex with SppA and Inhibits Its Protease Activity in Bacillus subtilis

M. Jules, J. V. van Dijl, A. Otto, 2020, mSphere.

Antibacterial Metabolites and Bacteriolytic Enzymes Produced by Bacillus pumilus During Bacteriolysis of Arthrobacter citreus

A. Otto, D. Becher, K. Riedel, 2015, Marine Biotechnology.

Iron Regulation in Clostridioides difficile

M. Beckstette, A. Otto, D. Becher, 2018, Front. Microbiol..

The protein inventory of Clostridium difficile grown in complex and minimal medium

M. Hecker, A. Otto, D. Becher, 2016, Proteomics. Clinical applications.

Laccase of Coriolus zonatus

A. Makower, A. Otto, S. Varfolomeyev, 1999, Applied biochemistry and biotechnology.

Novel twin-arginine translocation pathway-dependent phenotypes of Bacillus subtilis unveiled by quantitative proteomics.

M. Hecker, J. V. van Dijl, A. Otto, 2013, Journal of proteome research.

Enterococcus faecalis Glycolipids Modulate Lipoprotein-Content of the Bacterial Cell Membrane and Host Immune Response

A. Otto, D. Becher, P. Henneke, 2015, PloS one.

Differential daptomycin resistance development in Staphylococcus aureus strains with active and mutated gra regulatory systems.

P. François, T. Roemer, Xinwei Sher, 2017, International journal of medical microbiology : IJMM.

Picking vanished proteins from the void: how to collect and ship/share extremely dilute proteins in a reproducible and highly efficient manner.

M. Hecker, A. Otto, D. Becher, 2014, Analytical chemistry.

Global analysis of the impact of linezolid onto virulence factor production in S. aureus USA300.

S. Fuchs, J. Bernhardt, M. Hecker, 2016, International journal of medical microbiology : IJMM.

A Metaproteomics Approach to Elucidate Host and Pathogen Protein Expression during Catheter-Associated Urinary Tract Infections (CAUTIs)

Dieter Jahn, Jörg Bernhardt, Stephan Fuchs, 2015, Molecular & Cellular Proteomics.

Mapping of interactions between human macrophages and Staphylococcus aureus reveals an involvement of MAP kinase signaling in the host defense.

J. Bernhardt, M. Hecker, J. V. van Dijl, 2011, Journal of proteome research.

Metabolic and physiological interdependencies in the Bathymodiolus azoricus symbiosis

N. Dubilier, T. Schweder, N. Satoh, 2016, The ISME Journal.

Bacterioplankton reveal years-long retention of Atlantic deep-ocean water by the Tropic Seamount

R. Amann, B. Fuchs, B. Murton, 2020, Scientific Reports.

Surviving Serum: the Escherichia coli iss Gene of Extraintestinal Pathogenic E. coli Is Required for the Synthesis of Group 4 Capsule

D. Biran, E. Ron, A. Otto, 2021, Infection and immunity.

Comparative Proteomics of Purified Pathogen Vacuoles Correlates Intracellular Replication of Legionella pneumophila with the Small GTPase Ras-related protein 1 (Rap1) *

A. Otto, D. Becher, H. Hilbi, 2017, Molecular & Cellular Proteomics.

Bacillus pumilus KatX2 confers enhanced hydrogen peroxide resistance to a Bacillus subtilis PkatA::katX2 mutant strain

D. Zühlke, M. Hecker, T. Schweder, 2017, Microbial Cell Factories.

Grad-seq guides the discovery of ProQ as a major small RNA-binding protein

Konrad U. Förstner, Jörg Vogel, Konrad U Förstner, 2016, Proceedings of the National Academy of Sciences.

Analyses of soluble and membrane proteomes of Ralstonia eutropha H16 reveal major changes in the protein complement in adaptation to lithoautotrophy.

M. Hecker, A. Otto, D. Becher, 2011, Journal of proteome research.

Comparative Proteome Analysis of Spontaneous Outer Membrane Vesicles and Purified Outer Membranes of Neisseria meningitidis

A. Otto, D. Becher, U. Vogel, 2013, Journal of bacteriology.

The Staphylococcus aureus proteome.

M. Hecker, J. V. van Dijl, A. Otto, 2014, International journal of medical microbiology : IJMM.

Extracytoplasmic proteases determining the cleavage and release of secreted proteins, lipoproteins, and membrane proteins in Bacillus subtilis.

Dörte Becher, C. Harwood, J. V. van Dijl, 2013, Journal of proteome research.

Exoproteome Heterogeneity among Closely Related Staphylococcus aureus t437 Isolates and Possible Implications for Virulence

J. V. van Dijl, W. Quax, A. Otto, 2019, Journal of proteome research.

A Comprehensive Proteomics and Transcriptomics Analysis of Bacillus subtilis Salt Stress Adaptation

Michael Hecker, Erhard Bremer, Hannes Hahne, 2009, Journal of bacteriology.

Extracellular Proteome and Citrullinome of the Oral Pathogen Porphyromonas gingivalis.

J. V. van Dijl, A. Otto, D. Becher, 2016, Journal of proteome research.

Global quantification of phosphoproteins combining metabolic labeling and gel‐based proteomics in B. pumilus

M. Hecker, A. Otto, D. Becher, 2018, Electrophoresis.

Metabolic Labeling of Microorganisms with Stable Heavy Nitrogen Isotopes (15N).

A. Otto, 2018, Methods in molecular biology.

Surface shaving as a versatile tool to profile global interactions between human serum proteins and the Staphylococcus aureus cell surface

M. Hecker, H. Bonarius, J. V. van Dijl, 2011, Proteomics.

Penicillin‐binding protein folding is dependent on the PrsA peptidyl‐prolyl cis‐trans isomerase in Bacillus subtilis

O. Kuipers, A. Otto, D. Becher, 2010, Molecular microbiology.

A homopolymeric adenosine tract in the promoter region of nspA influences factor H-mediated serum resistance in Neisseria meningitidis

A. Otto, D. Becher, H. Claus, 2019, Scientific Reports.

Versatile vector suite for the extracytoplasmic production and purification of heterologous His-tagged proteins in Lactococcus lactis

J. V. van Dijl, A. Otto, D. Becher, 2015, Applied Microbiology and Biotechnology.

Global proteome analysis of vancomycin stress in Staphylococcus aureus.

J. Bernhardt, M. Hecker, A. Otto, 2013, International journal of medical microbiology : IJMM.

Spectral Library Based Analysis of Arginine Phosphorylations in Staphylococcus aureus*

M. Hecker, A. Otto, D. Becher, 2017, Molecular & Cellular Proteomics.

The phosphoproteome and its physiological dynamics in Staphylococcus aureus.

B. Maček, D. Zühlke, M. Hecker, 2014, International journal of medical microbiology : IJMM.

An ancient family of mobile genomic islands introducing cephalosporinase and carbapenemase genes in Enterobacteriaceae

J. V. van Dijl, A. Otto, D. Becher, 2018, Virulence.

Proteomic Signatures of Clostridium difficile Stressed with Metronidazole, Vancomycin, or Fidaxomicin

A. Otto, D. Becher, K. Riedel, 2018, Cells.

Comprehensive Redox Profiling of the Thiol Proteome of Clostridium difficile *

A. Otto, K. Riedel, Falko Hochgräfe, 2018, Molecular & Cellular Proteomics.

Gel-free and Gel-based Proteomics in Bacillus subtilis

Michael Hecker, Dörte Becher, Knut Büttner, 2006, Molecular & Cellular Proteomics.

Coping with anoxia: a comprehensive proteomic and transcriptomic survey of denitrification.

D. Zühlke, M. Hecker, A. Otto, 2014, Journal of proteome research.

Global relative and absolute quantitation in microbial proteomics.

J. Bernhardt, M. Hecker, A. Otto, 2012, Current opinion in microbiology.

Investigating Lactococcus lactis MG1363 Response to Phage p2 Infection at the Proteome Level*

A. Otto, D. Becher, S. Moineau, 2019, Molecular & Cellular Proteomics.

Antibacterial Metabolites and Bacteriolytic Enzymes Produced by Bacillus pumilus During Bacteriolysis of Arthrobacter citreus

A. Otto, D. Becher, K. Riedel, 2015, Marine Biotechnology.

A Proteomic View of an Important Human Pathogen – Towards the Quantification of the Entire Staphylococcus aureus Proteome

D. Zühlke, S. Fuchs, S. Engelmann, 2009, PloS one.

The Escherichia coli Type III Secretion System 2 Has a Global Effect on Cell Surface

U. Gophna, M. Hecker, D. Biran, 2018, mBio.

Life and Death of Proteins: A Case Study of Glucose-starved Staphylococcus aureus*

J. Bernhardt, M. Hecker, M. Lalk, 2012, Molecular & Cellular Proteomics.

Bacillus subtilis YqjG is required for genetic competence development

M. Hecker, A. Otto, D. Becher, 2011, Proteomics.

Functional association of the stress-responsive LiaH protein and the minimal TatAyCy protein translocase in Bacillus subtilis.

J. V. van Dijl, A. Otto, D. Becher, 2020, Biochimica et biophysica acta. Molecular cell research.

Identification of new protein-coding genes with a potential role in the virulence of the plant pathogen Xanthomonas euvesicatoria

U. Bonas, A. Otto, D. Becher, 2017, BMC Genomics.

Toward the Quantitative Characterization of Arginine Phosphorylations in Staphylococcus aureus.

M. Hecker, A. Otto, D. Becher, 2018, Journal of proteome research.

University of Groningen A Proteomic View of an Important Human Pathogen-Towards the Quantification of the Entire Staphylococcus aureus Proteome Becher,

D. Zühlke, S. Fuchs, S. Engelmann, 2009 .

Cadmium-detoxification in the earthworm Enchytraeus: specific expression of a putative aldehyde dehydrogenase.

A. Otto, F. Wunderlich, H. Schmitt-Wrede, 1996, Biochemical and biophysical research communications.

Tracking gene expression and oxidative damage of O2-stressed Clostridioides difficile by a multi-omics approach.

M. Beckstette, A. Otto, J. Hofmann, 2018, Anaerobe.

A Metabolic Labeling Strategy for Relative Protein Quantification in Clostridioides difficile

A. Otto, D. Becher, S. Maaß, 2018, Front. Microbiol..

A Trigger Enzyme in Mycoplasma pneumoniae: Impact of the Glycerophosphodiesterase GlpQ on Virulence and Gene Expression

S. Schmidl, J. Piñol, A. Otto, 2011, PLoS pathogens.

Differential effect of YidC depletion on the membrane proteome of Escherichia coli under aerobic and anaerobic growth conditions

M. Hecker, A. Otto, D. Becher, 2010, Proteomics.

Repression through a distal TCF-3 binding site restricts Xenopus myf-5 expression in gastrula mesoderm

Lei Xiao, A. Otto, W. Mei, 2002, Mechanisms of Development.