Kayoko Ohura

发表

Production of recombinant human dipeptidyl peptidase IV from Sf 9 cells in microbial fermenters

Ö. Aytekin, S. I. Gürhan, Kayoko Ohura, 2015 .

Design of Fexofenadine Prodrugs Based on Tissue-Specific Esterase Activity and Their Dissimilar Recognition by P-Glycoprotein.

Kayoko Ohura, T. Imai, Y. Nakada, 2015, Journal of pharmaceutical sciences.

Development of simultaneous quantification method of loteprednol etabonate (LE) and its acidic metabolites, and analysis of LE metabolism in rat

Kayoko Ohura, T. Imai, A. Samir, 2018, Xenobiotica; the fate of foreign compounds in biological systems.

Evaluation of transport mechanism of prodrugs and parent drugs formed by intracellular metabolism in Caco-2 cells with modified carboxylesterase activity: temocapril as a model case.

Teruko Imai, Kayoko Ohura, T. Imai, 2011, Journal of pharmaceutical sciences.

Development of a Caco-2 Cell Line Carrying the Human Intestine-Type CES Expression Profile as a Promising Tool for Ester-Containing Drug Permeability Studies.

Kayoko Ohura, T. Imai, H. Akita, 2018, Biological & pharmaceutical bulletin.

Elucidation of the Intestinal Absorption of para-Aminobenzoic Acid, a Marker for Dietary Intake.

Kayoko Ohura, T. Imai, Keiichiro Tanaka, 2017, Journal of pharmaceutical sciences.

Establishment and Characterization of a Novel Caco-2 Subclone with a Similar Low Expression Level of Human Carboxylesterase 1 to Human Small Intestine s

Kayoko Ohura, T. Imai, Hikaru Nishiyama, 2016 .

Establishment and Characterization of a Novel Caco-2 Subclone with a Similar Low Expression Level of Human Carboxylesterase 1 to Human Small Intestine

Kayoko Ohura, T. Imai, Hikaru Nishiyama, 2016, Drug Metabolism and Disposition.

Effect of intestinal first-pass hydrolysis on the oral bioavailability of an ester prodrug of fexofenadine.

Kayoko Ohura, T. Imai, Y. Adachi, 2012, Journal of pharmaceutical sciences.

Development of a Novel System for Estimating Human Intestinal Absorption Using Caco-2 Cells in the Absence of Esterase Activity

Kayoko Ohura, T. Imai, S. Ninomiya, 2010, Drug Metabolism and Disposition.

The role of intestinal carboxylesterase in the oral absorption of prodrugs.

Kayoko Ohura, T. Imai, 2010, Current drug metabolism.

Species difference of esterase expression and hydrolase activity in plasma.

Kayoko Ohura, T. Imai, T. Ogihara, 2012, Journal of pharmaceutical sciences.

Identification of Major Esterase Involved in Hydrolysis of Soft Anticholinergic (2R3'R-SGM) Designed From Glycopyrrolate in Human and Rat Tissues.

N. Bodor, Kayoko Ohura, T. Imai, 2019, Journal of pharmaceutical sciences.

Esterases Involved in the Rapid Bioconversion of Esmolol after Intravenous Injection in Humans.

Kayoko Ohura, T. Imai, Mizuki Isozaki, 2022, Biological & pharmaceutical bulletin.

Analysis of carboxylesterase 2 transcript variants in cynomolgus macaque liver

Kayoko Ohura, T. Imai, Y. Uno, 2019, Xenobiotica; the fate of foreign compounds in biological systems.

A novel quantification method for serine hydrolases in cellular expression system using fluorophosphonate‐biotin probe

Kayoko Ohura, T. Imai, Amira Abdel-Daim, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Differences in Intestinal Hydrolytic Activities between Cynomolgus Monkeys and Humans: Evaluation of Substrate Specificities Using Recombinant Carboxylesterase 2 Isozymes.

T. Hirokawa, Kayoko Ohura, T. Imai, 2016, Molecular pharmaceutics.

Effect of alcohol on skin permeation and metabolism of an ester‐type prodrug in Yucatan micropig skin

Kayoko Ohura, T. Imai, M. Fujii, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Monitoring of the effects of transfection with baculovirus on Sf9 cell line and expression of human dipeptidyl peptidase IV

Kayoko Ohura, T. Imai, Gaye Öngen, 2013, Cytotechnology.

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Kayoko Ohura, T. Imai, S. Ninomiya, 2009 .

Distinct Patterns of Aging Effects on the Expression and Activity of Carboxylesterases in Rat Liver and Intestine

Kayoko Ohura, T. Imai, M. Hashimoto, 2014, Drug Metabolism and Disposition.

Expression of Carboxylesterase Isozymes and Their Role in the Behavior of a Fexofenadine Prodrug in Rat Skin.

Kayoko Ohura, T. Imai, Y. Nakada, 2016, Journal of pharmaceutical sciences.

Molecular characterization and polymorphisms of butyrylcholinesterase in cynomolgus macaques

Kayoko Ohura, T. Imai, Y. Uno, 2018, Journal of medical primatology.

Production of recombinant human dipeptidyl peptidase IV from Sf9cells in microbial fermenters

Ö. Aytekin, S. I. Gürhan, Kayoko Ohura, 2016 .

Carboxylesterase in the liver and small intestine of experimental animals and human.

Teruko Imai, Kayoko Ohura, T. Imai, 2007, Life sciences.

Bioconversion and P-gp-mediated transport of depot fluphenazine prodrugs after intramuscular injection.

Kayoko Ohura, T. Imai, Y. Nakada, 2023, Journal of pharmaceutical sciences.

3D-fibroblast tissues constructed by a cell-coat technology enhance tight-junction formation of human colon epithelial cells.

M. Matsusaki, M. Akashi, Kayoko Ohura, 2015, Biochemical and biophysical research communications.

Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys

Kayoko Ohura, T. Imai, Naoya Wada, 2019, Drug Metabolism and Disposition.

Development of a Caco-2 Cell Line Carrying the Human Intestine-Type CES Expression Profile as a Promising Tool for Ester-Containing Drug Permeability Studies.

Kayoko Ohura, T. Imai, H. Akita, 2018, Biological & pharmaceutical bulletin.