Yan Shen

发表

Mastl is required for timely activation of APC/C in meiosis I and Cdk1 reactivation in meiosis II

P. Kaldis, D. Adhikari, M. K. Diril, 2014, The Journal of cell biology.

Life-long in vivo cell-lineage tracing shows that no oogenesis originates from putative germline stem cells in adult mice

J. Gustafsson, Kiran Busayavalasa, Yan Shen, 2014, Proceedings of the National Academy of Sciences.

The Safe Use of a PTEN Inhibitor for the Activation of Dormant Mouse Primordial Follicles and Generation of Fertilizable Eggs

D. Adhikari, S. Risal, Yan Shen, 2012, PloS one.

Somatic Cells Initiate Primordial Follicle Activation and Govern the Development of Dormant Oocytes in Mice

Kiran Busayavalasa, S. Risal, Yan Shen, 2014, Current Biology.

Maternal phosphatidylinositol 3‐kinase signalling is crucial for embryonic genome activation and preimplantation embryogenesis

T. Noda, Yan Shen, Kui Liu, 2010, EMBO reports.

DNA methylation in spermatogenesis and male infertility.

Yan Shen, Xuan Jing, Xiangrong Cui, 2016, Experimental and therapeutic medicine.

DNA methylation in spermatogenesis and male infertility ( Review )

Yan Shen, Xuan Jing, Xiangrong Cui, 2016 .

Cdk1, but not Cdk2, is the sole Cdk that is essential and sufficient to drive resumption of meiosis in mouse oocytes.

P. Kaldis, D. Adhikari, Yan Shen, 2012, Human molecular genetics.

p27kip1 (cyclin-dependent kinase inhibitor 1B) controls ovarian development by suppressing follicle endowment and activation and promoting follicle atresia in mice.

P. Kaldis, Yan Shen, Kui Liu, 2007, Molecular endocrinology.

Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles

A. Cooney, D. Adhikari, Yan Shen, 2009, Human molecular genetics.

Pharmacological Inhibition of mTORC1 Prevents Over-Activation of the Primordial Follicle Pool in Response to Elevated PI3K Signaling

D. Adhikari, S. Risal, Yan Shen, 2013, PloS one.

of primordial follicles

D. Adhikari, Yan Shen, Wenjing Zheng, 2009 .

Disruption of Tsc2 in oocytes leads to overactivation of the entire pool of primordial follicles.

M. Gambello, D. Adhikari, Yan Shen, 2009, Molecular human reproduction.

Cdk1 drives meiosis and mitosis through two different mechanisms

D. Adhikari, Yan Shen, Kui Liu, 2012, Cell cycle.

Adult human and mouse ovaries lack DDX4-expressing functional oogonial stem cells

R. Sandberg, J. Gustafsson, S. Petropoulos, 2015, Nature Medicine.

Two classes of ovarian primordial follicles exhibit distinct developmental dynamics and physiological functions

Kui Liu, S. Risal, Yan Shen, 2013, Human molecular genetics.

mTORC1 Signaling in Oocytes Is Dispensable for the Survival of Primordial Follicles and for Female Fertility

D. Adhikari, Rebecca Lindkvist, Yan Shen, 2014, PloS one.

Formation of E-cadherin-mediated cell-cell adhesion activates AKT and mitogen activated protein kinase via phosphatidylinositol 3 kinase and ligand-independent activation of epidermal growth factor receptor in ovarian cancer cells.

Yan Shen, Kui Liu, P. Reddy, 2005, Molecular endocrinology.

Experimental evidence showing that no mitotically active female germline progenitors exist in postnatal mouse ovaries

D. Adhikari, Yan Shen, Kui Liu, 2012, Proceedings of the National Academy of Sciences.

Infertility caused by retardation of follicular development in mice with oocyte-specific expression of Foxo3a

Yan Shen, Kui Liu, C. Du, 2007, Development.

Oocyte-Specific Deletion of Pten Causes Premature Activation of the Primordial Follicle Pool

A. Cooney, D. Adhikari, Yan Shen, 2008, Science.

Phosphorylation and inactivation of glycogen synthase kinase-3 by soluble kit ligand in mouse oocytes during early follicular development.

Yan Shen, Kui Liu, C. Du, 2007, Journal of molecular endocrinology.

Phosphorylation and inactivation of glycogen synthase kinase-3 by soluble kit ligand in mouse oocytes during early follicular development.

Yan Shen, Kui Liu, C. Du, 2007, Journal of molecular endocrinology.