S. Marchi

发表

The endoplasmic reticulum-mitochondria connection: one touch, multiple functions.

Saverio Marchi, Paolo Pinton, P. Pinton, 2014, Biochimica et biophysica acta.

Oncogenic and oncosuppressive signal transduction at mitochondria-associated endoplasmic reticulum membranes

P. Pinton, S. Marchi, C. Giorgi, 2014, Molecular & cellular oncology.

Protein Kinases and Phosphatases in the Control of Cell Fate

P. Pinton, S. Marchi, S. Patergnani, 2011, Enzyme research.

Citrate Mediates Crosstalk between Mitochondria and the Nucleus to Promote Human Mesenchymal Stem Cell In Vitro Osteogenesis

P. Pinton, S. Marchi, C. Giorgi, 2020, Cells.

Mitochondrial calcium homeostasis as potential target for mitochondrial medicine

P. Pinton, S. Marchi, S. Patergnani, 2012, Mitochondrion.

Mitochondria in Multiple Sclerosis: Molecular Mechanisms of Pathogenesis.

V. Fossati, P. Pinton, S. Marchi, 2017, International review of cell and molecular biology.

Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death.

P. Pinton, S. Marchi, S. Patergnani, 2018, Cell calcium.

Endoplasmic Reticulum-Mitochondria Communication Through Ca2+ Signaling: The Importance of Mitochondria-Associated Membranes (MAMs).

P. Pinton, S. Marchi, S. Patergnani, 2017, Advances in experimental medicine and biology.

Intramitochondrial calcium regulation by the FHIT gene product sensitizes to apoptosis

C. Croce, K. Huebner, P. Pinton, 2009, Proceedings of the National Academy of Sciences.

Mitophagy in Cardiovascular Diseases

P. Pinton, S. Marchi, S. Patergnani, 2020, Journal of clinical medicine.

Calcium signaling around Mitochondria

P. Pinton, S. Marchi, S. Patergnani, 2011 .

Methods to Assess Mitochondrial Morphology in Mammalian Cells Mounting Autophagic or Mitophagic Responses.

P. Pinton, S. Marchi, S. Patergnani, 2017, Methods in enzymology.

Molecular Characterization of the Dominant-Negative Role of Cancer-Associated PTEN: Sometimes, Null is Better

P. Pinton, S. Marchi, 2014, Front. Oncol..

Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy

V. Tiranti, C. Tacchetti, C. La Morgia, 2022, Cell reports.

Methods to Monitor Mitophagy and Mitochondrial Quality: Implications in Cancer, Neurodegeneration, and Cardiovascular Diseases.

M. Previati, P. Pinton, S. Marchi, 2021, Methods in molecular biology.

Alterations of calcium homeostasis in cancer cells.

P. Pinton, S. Marchi, 2016, Current opinion in pharmacology.

Beyond multiple mechanisms and a unique drug: Defective autophagy as pivotal player in cerebral cavernous malformation pathogenesis and implications for targeted therapies

P. Pinton, S. Marchi, L. Goitre, 2016, Rare diseases.

Control of host mitochondria by bacterial pathogens.

L. Galluzzi, P. Pinton, S. Marchi, 2021, Trends in microbiology.

IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice.

P. Pinton, S. Marchi, A. Contreras-Ferrat, 2018, Biochimica et biophysica acta. Molecular basis of disease.

KRIT1 Deficiency Promotes Aortic Endothelial Dysfunction

R. Ferrari, P. Pinton, S. Marchi, 2019, International journal of molecular sciences.

Antipsychotic drugs counteract autophagy and mitophagy in multiple sclerosis

M. Previati, P. Pinton, S. Marchi, 2021, Proceedings of the National Academy of Sciences.

The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications

P. Pinton, S. Marchi, 2014, The Journal of physiology.

Tumor necrosis factor-α impairs oligodendroglial differentiation through a mitochondria-dependent process

T. Pozzan, P. Pinton, S. Marchi, 2014, Cell Death and Differentiation.

Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis

P. Pinton, S. Marchi, S. Patergnani, 2015, Nature Communications.

Detection of p62/SQSTM1 Aggregates in Cellular Models of CCM Disease by Immunofluorescence.

P. Pinton, S. Marchi, S. Retta, 2020, Methods in molecular biology.

Mitochondria in the line of fire

P. Pinton, S. Marchi, 2022, Cell Death & Differentiation.

Endoplasmic reticulum/mitochondria calcium cross-talk.

P. Pinton, S. Marchi, E. Zecchini, 2007, Novartis Foundation symposium.

High mitochondrial Ca2+ content increases cancer cell proliferation upon inhibition of mitochondrial permeability transition pore (mPTP)

P. Pinton, S. Marchi, S. Patergnani, 2019, Cell cycle.

The chaperone‐like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation

P. Pinton, S. Marchi, F. Bernardi, 2018, Journal of thrombosis and haemostasis : JTH.

The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation.

P. Provero, A. Bardelli, L. Trusolino, 2021, Cell reports.

ATP synthesis and storage

P. Pinton, S. Marchi, S. Patergnani, 2012, Purinergic Signalling.

Selective modulation of subtype III IP3R by Akt regulates ER Ca2+ release and apoptosis

P. Pinton, S. Marchi, C. Giorgi, 2012, Cell Death and Disease.

Akt kinase reducing endoplasmic reticulum Ca2+ release protects cells from Ca2+-dependent apoptotic stimuli.

P. Pinton, S. Marchi, C. Giorgi, 2008, Biochemical and biophysical research communications.

Identification of PTEN at the ER and MAMs and its regulation of Ca2+ signaling and apoptosis in a protein phosphatase-dependent manner

P. Pandolfi, P. Pinton, S. Marchi, 2013, Cell Death and Differentiation.

Redox control of protein kinase C: cell- and disease-specific aspects.

P. Pinton, S. Marchi, S. Patergnani, 2010, Antioxidants & redox signaling.

Mitochondria-Ros Crosstalk in the Control of Cell Death and Aging

P. Pinton, S. Marchi, S. Patergnani, 2011, Journal of signal transduction.

Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases.

H. Zischka, A. Dobrzyń, P. Portincasa, 2018, International review of cell and molecular biology.

ATP synthesis and storage

P. Pinton, S. Marchi, S. Patergnani, 2012, Purinergic Signalling.

Protein Kinase C ß and Prolyl Isomerase 1 Regulate Mitochondrial Effects of the Life-Span Determinant p66Shc

S. Minucci, P. Pelicci, M. Giorgio, 2007, Science.

Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75.

P. Pinton, S. Marchi, F. Ciccosanti, 2018, Cell reports.

The machineries, regulation and cellular functions of mitochondrial calcium

P. Pinton, S. Marchi, C. Giorgi, 2018, Nature Reviews Molecular Cell Biology.

Alterations in Ca2+ Signalling via ER-Mitochondria Contact Site Remodelling in Cancer.

P. Pinton, S. Marchi, C. Giorgi, 2017, Advances in experimental medicine and biology.

P. Pinton, S. Marchi, C. Giorgi, 2020, Reviews of physiology, biochemistry and pharmacology.

Translational readthrough of GLA nonsense mutations suggests dominant-negative effects exerted by the interaction of wild-type and missense variants

P. Pinton, S. Marchi, F. Bernardi, 2019, RNA biology.

Mitochondria-Associated Endoplasmic Reticulum Membranes Microenvironment: Targeting Autophagic and Apoptotic Pathways in Cancer Therapy

S. Marchi, S. Patergnani, C. Giorgi, 2015, Front. Oncol..

Mitochondria-associated membranes (MAMs) as hotspot Ca(2+) signaling units.

P. Pinton, S. Marchi, S. Patergnani, 2012, Advances in experimental medicine and biology.

Ca(2+) transfer from the ER to mitochondria: when, how and why.

Carlotta Giorgi, Saverio Marchi, Paolo Pinton, 2009, Biochimica et biophysica acta.

Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition

L. Galluzzi, G. Kroemer, P. Pinton, 2013, Cell cycle.

Calcium signaling around Mitochondria Associated Membranes (MAMs)

Carlotta Giorgi, Saverio Marchi, Paolo Pinton, 2011, Cell Communication and Signaling.

Downregulation of the Mitochondrial Calcium Uniporter by Cancer-Related miR-25

M. Negrini, R. Gafà, G. Lanza, 2013, Current Biology.

Akt‐mediated phosphorylation of MICU1 regulates mitochondrial Ca2+ levels and tumor growth

L. Galluzzi, G. Kroemer, P. Pinton, 2018, The EMBO journal.

Mitochondrial calcium uniporter complex modulation in cancerogenesis

P. Pinton, S. Marchi, C. Giorgi, 2019, Cell cycle.

Mitochondrial Ca2+ and apoptosis

P. Pinton, S. Marchi, S. Patergnani, 2012, Cell calcium.

Ca2+ Fluxes and Cancer.

L. Galluzzi, P. Pinton, S. Marchi, 2020, Molecular cell.

Noncanonical Cell Fate Regulation by Bcl-2 Proteins.

L. Galluzzi, G. Kroemer, S. Marchi, 2020, Trends in cell biology.

Defective autophagy is a key feature of cerebral cavernous malformations

E. Dejana, P. Cassoni, P. Pinton, 2015, EMBO molecular medicine.

Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death

P. Pinton, S. Marchi, C. Giorgi, 2016, Molecular biology of the cell.

KRIT1 Regulates the Homeostasis of Intracellular Reactive Oxygen Species

P. Degan, P. Pinton, S. Marchi, 2010, PloS one.

The machineries, regulation and cellular functions of mitochondrial calcium

P. Pinton, S. Marchi, C. Giorgi, 2018, Nature Reviews Molecular Cell Biology.

H-Ras-driven tumoral maintenance is sustained through caveolin-1-dependent alterations in calcium signaling

P. Pinton, S. Marchi, S. Patergnani, 2014, Oncogene.

Role of Mitochondria-Associated ER Membranes in Calcium Regulation in Cancer-Specific Settings1

P. Pinton, S. Marchi, C. Giorgi, 2018, Neoplasia.

Interorganellar calcium signaling in the regulation of cell metabolism: A cancer perspective.

P. Pinton, S. Marchi, C. Giorgi, 2020, Seminars in cell & developmental biology.

Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson’s disease

P. Calabresi, A. Tozzi, P. Pinton, 2018, Cell Death & Disease.

PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment

F. Di Virgilio, R. Gafà, G. Lanza, 2022, Cell Death & Differentiation.

PRKCB/protein kinase C, beta and the mitochondrial axis as key regulators of autophagy

Carlotta Giorgi, Saverio Marchi, Paolo Pinton, 2013, Autophagy.

PERK recruits E-Syt1 at ER–mitochondria contacts for mitochondrial lipid transport and respiration

P. Agostinis, P. Pinton, S. Marchi, 2023, The Journal of cell biology.

Use of luciferase probes to measure ATP in living cells and animals

F. Di Virgilio, P. Pinton, S. Marchi, 2017, Nature Protocols.

Editorial: Organelles Relationships and Interactions: A Cancer Perspective

B. Delprat, S. Marchi, S. Patergnani, 2021, Frontiers in Cell and Developmental Biology.

Subcellular calcium measurements in mammalian cells using jellyfish photoprotein aequorin-based probes

P. Pinton, S. Marchi, S. Patergnani, 2013, Nature Protocols.

Perturbed mitochondrial Ca2+ signals as causes or consequences of mitophagy induction

P. Pinton, S. Marchi, S. Patergnani, 2013, Autophagy.

Cellular processes underlying cerebral cavernous malformations: Autophagy as another point of view

P. Pinton, S. Marchi, S. Retta, 2016, Autophagy.

Impaired mitochondrial quality control in Rett Syndrome.

C. Cervellati, P. Pinton, S. Marchi, 2021, Archives of biochemistry and biophysics.

TFEB-mediated increase in peripheral lysosomes regulates store-operated calcium entry

A. Ballabio, P. Pinton, S. Marchi, 2017, Scientific Reports.

Ca2+ signaling and cell death.

L. Galluzzi, P. Pinton, S. Marchi, 2023, Cell calcium.

Mitochondrial calcium uniporter, MiRNA and cancer

P. Pinton, S. Marchi, 2013, Communicative & integrative biology.

Autophagy and mitophagy elements are increased in body fluids of multiple sclerosis-affected individuals

E. Granieri, P. Pinton, S. Marchi, 2017, Journal of Neurology, Neurosurgery, and Psychiatry.

MitopatHs: a new logically-framed tool for visualizing multiple mitochondrial pathways

P. Pinton, S. Marchi, G. Boniolo, 2021, iScience.

Mitochondrial calcium : mechanisms of transport , regulation and 1 cellular functions [ Au : OK ? Or ‘ Mitochondrial calcium : 2 machineries , regulation and cellular functions ’ ? ]

P. Pinton, S. Marchi, C. Giorgi, 2021 .