S. Patergnani

发表

The endoplasmic reticulum-mitochondria connection: one touch, multiple functions.

Saverio Marchi, Paolo Pinton, P. Pinton, 2014, Biochimica et biophysica acta.

Protein Kinases and Phosphatases in the Control of Cell Fate

P. Pinton, S. Marchi, S. Patergnani, 2011, Enzyme research.

Calcium Dynamics as a Machine for Decoding Signals.

P. Pinton, S. Patergnani, C. Giorgi, 2018, Trends in cell biology.

Methods to monitor and compare mitochondrial and glycolytic ATP production.

P. Pinton, S. Patergnani, M. Wieckowski, 2014, Methods in enzymology.

Mitochondria-associated membranes (MAMs) and inflammation

M. Previati, S. Patergnani, C. Giorgi, 2018, Cell Death & Disease.

Relevance of Autophagy and Mitophagy Dynamics and Markers in Neurodegenerative Diseases

M. Previati, P. Pinton, S. Patergnani, 2021, Biomedicines.

Fluorescent Light Energy (FLE) Acts on Mitochondrial Physiology Improving Wound Healing

L. Hébert, F. Bassetto, P. Pinton, 2020, Journal of clinical medicine.

Mitochondrial calcium homeostasis as potential target for mitochondrial medicine

P. Pinton, S. Marchi, S. Patergnani, 2012, Mitochondrion.

Calcium regulates cell death in cancer: Roles of the mitochondria and mitochondria-associated membranes (MAMs).

M. Previati, P. Pinton, S. Patergnani, 2017, Biochimica et biophysica acta. Bioenergetics.

Mitochondria in Multiple Sclerosis: Molecular Mechanisms of Pathogenesis.

V. Fossati, P. Pinton, S. Marchi, 2017, International review of cell and molecular biology.

Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death.

P. Pinton, S. Marchi, S. Patergnani, 2018, Cell calcium.

Endoplasmic Reticulum-Mitochondria Communication Through Ca2+ Signaling: The Importance of Mitochondria-Associated Membranes (MAMs).

P. Pinton, S. Marchi, S. Patergnani, 2017, Advances in experimental medicine and biology.

Endoplasmic reticulum-mitochondria Ca2+ crosstalk in the control of the tumor cell fate.

M. Previati, P. Pinton, S. Patergnani, 2017, Biochimica et biophysica acta. Molecular cell research.

PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer Development

P. Pandolfi, E. Magri, G. Kroemer, 2016, Cell reports.

Update on Calcium Signaling in Cystic Fibrosis Lung Disease

P. Pinton, S. Patergnani, A. Rimessi, 2021, Frontiers in Pharmacology.

BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene × environment interaction with asbestos

J. Onuchic, S. Pastorino, H. Pass, 2021, Proceedings of the National Academy of Sciences.

LonP1 Differently Modulates Mitochondrial Function and Bioenergetics of Primary Versus Metastatic Colon Cancer Cells

A. Iannone, L. Roncucci, P. Pinton, 2018, Front. Oncol..

Mitophagy in Cardiovascular Diseases

P. Pinton, S. Marchi, S. Patergnani, 2020, Journal of clinical medicine.

Calcium signaling around Mitochondria

P. Pinton, S. Marchi, S. Patergnani, 2011 .

The “mitochondrial stress responses”: the “Dr. Jekyll and Mr. Hyde” of neuronal disorders

P. Pinton, S. Patergnani, A. Rimessi, 2022, Neural regeneration research.

Methods to Assess Mitochondrial Morphology in Mammalian Cells Mounting Autophagic or Mitophagic Responses.

P. Pinton, S. Marchi, S. Patergnani, 2017, Methods in enzymology.

Various Aspects of Calcium Signaling in the Regulation of Apoptosis, Autophagy, Cell Proliferation, and Cancer

M. Previati, G. Aguiari, P. Pinton, 2020, International journal of molecular sciences.

Aortic Valve Stenosis and Mitochondrial Dysfunctions: Clinical and Molecular Perspectives

R. Ferrari, P. Pinton, S. Patergnani, 2020, International journal of molecular sciences.

Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy

V. Tiranti, C. Tacchetti, C. La Morgia, 2022, Cell reports.

Impairment of mitophagy and autophagy accompanies calcific aortic valve stenosis favoring cell death and the severity of disease.

R. Ferrari, P. Pinton, S. Patergnani, 2021, Cardiovascular research.

Syndromic parkinsonism and dementia associated with OPA 1 missense mutations

M. Zeviani, G. Rizzo, P. Barboni, 2015, Annals of neurology.

Methods to Monitor Mitophagy and Mitochondrial Quality: Implications in Cancer, Neurodegeneration, and Cardiovascular Diseases.

M. Previati, P. Pinton, S. Marchi, 2021, Methods in molecular biology.

Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy

S. Pastorino, T. Mak, H. Pass, 2020, Proceedings of the National Academy of Sciences.

Molecular Mechanisms of Autophagy in Cancer Development, Progression, and Therapy

P. Pinton, S. Patergnani, C. Giorgi, 2022, Biomedicines.

Calcium mishandling in absence of primary mitochondrial dysfunction drives cellular pathology in Wolfram Syndrome

G. Savini, P. Barboni, M. Carbonelli, 2020, Scientific Reports.

Antipsychotic drugs counteract autophagy and mitophagy in multiple sclerosis

M. Previati, P. Pinton, S. Marchi, 2021, Proceedings of the National Academy of Sciences.

The Multifaceted Roles of Autophagy in Infectious, Obstructive, and Malignant Airway Diseases

P. Pinton, S. Patergnani, C. Giorgi, 2022, Biomedicines.

Tumor necrosis factor-α impairs oligodendroglial differentiation through a mitochondria-dependent process

T. Pozzan, P. Pinton, S. Marchi, 2014, Cell Death and Differentiation.

Calcium homeostasis in the control of mitophagy.

P. Pinton, S. Patergnani, C. Giorgi, 2022, Antioxidants & redox signaling.

Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis

P. Pinton, S. Marchi, S. Patergnani, 2015, Nature Communications.

From Bed to Bench and Back: TNF-α, IL-23/IL-17A, and JAK-Dependent Inflammation in the Pathogenesis of Psoriatic Synovitis

P. Pinton, S. Patergnani, C. Giorgi, 2021, Frontiers in Pharmacology.

Sertoli Cells as potential Pharmaceutical Carriers: uptake and stability

S. Patergnani, S. Capitani, L. Neri, 2013 .

Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models

B. Delprat, M. Thiry, P. Pinton, 2022, Science Translational Medicine.

Human adipose stem cells induced to osteogenic differentiation by an innovative collagen/hydroxylapatite hybrid scaffold

S. Patergnani, M. Tognon, A. D'Agostino, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Rehabilitation Improves Mitochondrial Energetics in Progressive Multiple Sclerosis: The Significant Role of Robot-Assisted Gait Training and of the Personalized Intensity

N. Basaglia, S. Straudi, P. Pinton, 2020, Diagnostics.

High mitochondrial Ca2+ content increases cancer cell proliferation upon inhibition of mitochondrial permeability transition pore (mPTP)

P. Pinton, S. Marchi, S. Patergnani, 2019, Cell cycle.

Calcium dysregulation in heart diseases: targeting calcium channels to achieve a correct calcium homeostasis.

P. Pinton, S. Patergnani, C. Giorgi, 2022, Pharmacological research.

Hydroxylapatite‐collagen hybrid scaffold induces human adipose‐derived mesenchymal stem cells to osteogenic differentiation in vitro and bone regrowth in patients

S. Patergnani, C. Giorgi, M. Tognon, 2019, Stem cells translational medicine.

ATP synthesis and storage

P. Pinton, S. Marchi, S. Patergnani, 2012, Purinergic Signalling.

Redox control of protein kinase C: cell- and disease-specific aspects.

P. Pinton, S. Marchi, S. Patergnani, 2010, Antioxidants & redox signaling.

Mitochondria-Ros Crosstalk in the Control of Cell Death and Aging

P. Pinton, S. Marchi, S. Patergnani, 2011, Journal of signal transduction.

Mitochondrial Oxidative Stress and “Mito-Inflammation”: Actors in the Diseases

P. Pinton, S. Patergnani, A. Rimessi, 2021, Biomedicines.

NRIP1/RIP140 siRNA-mediated attenuation counteracts mitochondrial dysfunction in Down syndrome.

M. Zannini, T. de Cristofaro, P. Pinton, 2014, Human molecular genetics.

ATP synthesis and storage

P. Pinton, S. Marchi, S. Patergnani, 2012, Purinergic Signalling.

BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation

S. Pastorino, H. Pass, L. Ferris, 2017, Nature.

Mitochondria-Associated Endoplasmic Reticulum Membranes Microenvironment: Targeting Autophagic and Apoptotic Pathways in Cancer Therapy

S. Marchi, S. Patergnani, C. Giorgi, 2015, Front. Oncol..

Mitochondria-associated membranes (MAMs) as hotspot Ca(2+) signaling units.

P. Pinton, S. Marchi, S. Patergnani, 2012, Advances in experimental medicine and biology.

Physiopathology of the Permeability Transition Pore: Molecular Mechanisms in Human Pathology

P. Pinton, S. Patergnani, C. Giorgi, 2020, Biomolecules.

Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition

L. Galluzzi, G. Kroemer, P. Pinton, 2013, Cell cycle.

Calcium signaling around Mitochondria Associated Membranes (MAMs)

Carlotta Giorgi, Saverio Marchi, Paolo Pinton, 2011, Cell Communication and Signaling.

Understanding the Role of Autophagy in Cancer Formation and Progression Is a Real Opportunity to Treat and Cure Human Cancers

P. Pinton, S. Patergnani, C. Giorgi, 2021, Cancers.

Downregulation of the Mitochondrial Calcium Uniporter by Cancer-Related miR-25

M. Negrini, R. Gafà, G. Lanza, 2013, Current Biology.

Mitochondria-associated membranes: composition, molecular mechanisms, and physiopathological implications.

P. Pinton, S. Patergnani, C. Giorgi, 2015, Antioxidants & redox signaling.

Different Roles of Mitochondria in Cell Death and Inflammation: Focusing on Mitochondrial Quality Control in Ischemic Stroke and Reperfusion

P. Pinton, S. Patergnani, C. Giorgi, 2021, Biomedicines.

Mitochondrial Ca2+ and apoptosis

P. Pinton, S. Marchi, S. Patergnani, 2012, Cell calcium.

Autophagy and mitophagy biomarkers are reduced in sera of patients with Alzheimer’s disease and mild cognitive impairment

D. Seripa, P. Pinton, S. Patergnani, 2019, Scientific Reports.

Defective autophagy is a key feature of cerebral cavernous malformations

E. Dejana, P. Cassoni, P. Pinton, 2015, EMBO molecular medicine.

Mitochondrial Ca2+ Remodeling is a Prime Factor in Oncogenic Behavior

P. Pinton, S. Patergnani, M. Wieckowski, 2015, Front. Oncol..

H-Ras-driven tumoral maintenance is sustained through caveolin-1-dependent alterations in calcium signaling

P. Pinton, S. Marchi, S. Patergnani, 2014, Oncogene.

Mitochondrial Stress Responses and “Mito-Inflammation” in Cystic Fibrosis

P. Pinton, S. Patergnani, A. Rimessi, 2020, Frontiers in Pharmacology.

Editorial: Targeting the Wnt/β-catenin signaling pathway in cancer

G. Piazza, S. Patergnani, D. Buchsbaum, 2022, Frontiers in Oncology.

The Interplay of Hypoxia Signaling on Mitochondrial Dysfunction and Inflammation in Cardiovascular Diseases and Cancer: From Molecular Mechanisms to Therapeutic Approaches

P. Pinton, S. Patergnani, C. Giorgi, 2022, Biology.

The induction of AMPK-dependent autophagy leads to P53 degradation and affects cell growth and migration in kidney cancer cells.

G. Aguiari, P. Pinton, S. Patergnani, 2020, Experimental cell research.

Mitochondria-associated membranes (MAMs) and inflammation

M. Previati, S. Patergnani, C. Giorgi, 2018, Cell Death & Disease.

The Dichotomous Role of Inflammation in the CNS: A Mitochondrial Point of View

P. Pinton, S. Patergnani, C. Giorgi, 2020, Biomolecules.

The inhibition of MDM2 slows cell proliferation and activates apoptosis in ADPKD cell lines

N. Bianchi, G. Aguiari, P. Pinton, 2022, Biology of the cell.

Correlation between auto/mitophagic processes and magnetic resonance imaging activity in multiple sclerosis patients

E. Granieri, P. Pinton, S. Patergnani, 2019, Journal of Neuroinflammation.

Mitophagy and mitochondrial balance.

P. Pinton, S. Patergnani, 2015, Methods in molecular biology.

PRKCB/protein kinase C, beta and the mitochondrial axis as key regulators of autophagy

Carlotta Giorgi, Saverio Marchi, Paolo Pinton, 2013, Autophagy.

Chemoresistance and Cancer-Related Inflammation: Two Hallmarks of Cancer Connected by an Atypical Link, PKCζ

P. Pinton, S. Patergnani, A. Rimessi, 2013, Front. Oncol..

Adding a “Notch” to Cardiovascular Disease Therapeutics: A MicroRNA-Based Approach

R. Ferrari, P. Pinton, S. Patergnani, 2021, Frontiers in Cell and Developmental Biology.

Mitochondrial functionality and metabolism in T cells from progressive multiple sclerosis patients

P. Pinton, S. Patergnani, A. Cossarizza, 2019, European journal of immunology.

Editorial: Organelles Relationships and Interactions: A Cancer Perspective

B. Delprat, S. Marchi, S. Patergnani, 2021, Frontiers in Cell and Developmental Biology.

ER-mitochondria cross-talk is regulated by the Ca2+ sensor NCS1 and is impaired in Wolfram syndrome

B. Delprat, D. Milea, M. Thiry, 2018, Science Signaling.

Subcellular calcium measurements in mammalian cells using jellyfish photoprotein aequorin-based probes

P. Pinton, S. Marchi, S. Patergnani, 2013, Nature Protocols.

Measurement of ATP concentrations in mitochondria of living cells using luminescence and fluorescence approaches.

P. Pinton, S. Patergnani, C. Giorgi, 2020, Methods in cell biology.

Calcium mishandling in absence of primary mitochondrial dysfunction drives cellular pathology in Wolfram Syndrome

G. Savini, P. Barboni, M. Carbonelli, 2020, Scientific Reports.

Perturbed mitochondrial Ca2+ signals as causes or consequences of mitophagy induction

P. Pinton, S. Marchi, S. Patergnani, 2013, Autophagy.

The Tricky Connection between Extracellular Vesicles and Mitochondria in Inflammatory-Related Diseases

P. Pinton, S. Patergnani, C. Giorgi, 2023, International journal of molecular sciences.

1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects

P. Pinton, S. Patergnani, C. Giorgi, 2023, International journal of molecular sciences.

Vav1 is necessary for PU.1 mediated upmodulation of miR‐29b in acute myeloid leukaemia‐derived cells

P. Pinton, S. Patergnani, S. Capitani, 2018, Journal of cellular and molecular medicine.

Germline BAP1 mutations induce a Warburg effect

S. Pastorino, H. Pass, Wei Jia, 2017, Cell Death and Differentiation.

Metformin Induces Apoptosis and Inhibits Notch1 in Malignant Pleural Mesothelioma Cells

P. Pinton, S. Patergnani, M. Tognon, 2021, Frontiers in Cell and Developmental Biology.

Autophagy and mitophagy elements are increased in body fluids of multiple sclerosis-affected individuals

E. Granieri, P. Pinton, S. Marchi, 2017, Journal of Neurology, Neurosurgery, and Psychiatry.

Evaluation of the Synovial Effects of Biological and Targeted Synthetic DMARDs in Patients with Psoriatic Arthritis: A Systematic Literature Review and Meta-Analysis

R. Gafà, G. Lanza, P. Pinton, 2023, International journal of molecular sciences.

The endoplasmic reticulum mitochondrial calcium cross talk is downregulated in malignant pleural mesothelioma cells and plays a critical role in apoptosis inhibition

P. Pinton, S. Patergnani, C. Giorgi, 2015, Oncotarget.

Mitochondrial Dysfunction and Skeletal Muscle Atrophy: Causes, Mechanisms, and Treatment Strategies.

P. Pinton, S. Patergnani, E. Tremoli, 2023, Mitochondrion.

The Complex Relationship between Hypoxia Signaling, Mitochondrial Dysfunction and Inflammation in Calcific Aortic Valve Disease: Insights from the Molecular Mechanisms to Therapeutic Approaches

P. Pinton, S. Patergnani, C. Giorgi, 2023, International journal of molecular sciences.

Correlation between auto/mitophagic processes and magnetic resonance imaging activity in multiple sclerosis patients

E. Granieri, P. Pinton, S. Patergnani, 2019, Journal of Neuroinflammation.

Perturbed mitochondrial Ca2+ signals as causes or consequences of mitophagy induction

P. Pinton, S. Marchi, S. Patergnani, 2013, Autophagy.

Mitochondrial calcium homeostasis as potential target for mitochondrial medicine

P. Pinton, S. Marchi, S. Patergnani, 2012, Mitochondrion.

ER-mitochondria cross-talk is regulated by the Ca2+ sensor NCS1 and is impaired in Wolfram syndrome

B. Delprat, D. Milea, M. Thiry, 2018, Science Signaling.

NRIP1/RIP140 siRNA-mediated attenuation counteracts mitochondrial dysfunction in Down syndrome.

M. Zannini, T. de Cristofaro, P. Pinton, 2014, Human molecular genetics.

Defective autophagy is a key feature of cerebral cavernous malformations

E. Dejana, P. Cassoni, P. Pinton, 2015, EMBO molecular medicine.

Tofacitinib restores psoriatic arthritis fibroblast-like synoviocytes function via autophagy and mitochondrial quality control modulation.

R. Gafà, P. Pinton, S. Patergnani, 2023, Journal of autoimmunity.

Osteosarcoma cell death induced by innovative scaffolds doped with chemotherapeutics

S. Patergnani, C. Giorgi, A. Tampieri, 2024, Journal of cellular physiology.

Hsa-microRNA-1249-3p/Homeobox A13 axis modulates the expression of β-catenin gene in human epithelial cells

R. Gafà, P. Pinton, S. Patergnani, 2023, Scientific reports.

Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis

P. Pinton, S. Marchi, S. Patergnani, 2015, Nature Communications.

ErbB2-NOTCH1 axis controls autophagy in cardiac cells.

S. Patergnani, F. Vieceli Dalla Sega, F. Fortini, 2024, BioFactors.