D. Ren

发表

Cell line profiling to improve monoclonal antibody production

Kristi Daris, Da Ren, Roman Zubarev, 2014, Biotechnology and bioengineering.

Discovery and Characterization of a Photo-Oxidative Histidine-Histidine Cross-Link in IgG1 Antibody Utilizing 18O-Labeling and Mass Spectrometry

Zhongqi Zhang, Da Ren, Zhongqi Zhang, 2014, Analytical chemistry.

Proteomics analysis of altered cellular metabolism induced by insufficient copper level.

Gang Xiao, P. Bondarenko, Zhongqi Zhang, 2014, Journal of biotechnology.

Discovery of undefined protein cross-linking chemistry: a comprehensive methodology utilizing 18O-labeling and mass spectrometry.

Zhongqi Zhang, Da Ren, Zhongqi Zhang, 2013, Analytical chemistry.

An improved trypsin digestion method minimizes digestion-induced modifications on proteins.

Liang-Yu Shih, Da Ren, Michael J Treuheit, 2009, Analytical biochemistry.

Degradation products analysis of an Fc fusion protein using LC/MS methods.

D. Brems, P. Bondarenko, D. Ren, 2009, International journal of biological macromolecules.

Structure elucidation of highly polar basic degradants by on-line hydrogen/deuterium exchange hydrophilic interaction chromatography coupled to tandem mass spectrometry.

D. Ren, J. Cheetham, Z. Zhou, 2010, Journal of chromatography. A.

Top-down N-terminal sequencing of Immunoglobulin subunits with electrospray ionization time of flight mass spectrometry.

P. Bondarenko, D. Ren, D. Hambly, 2009, Analytical biochemistry.

Gas Phase Ion Chemistry to Determine Isoaspartate in a Peptide Backbone

R. M. Bain, R. Cooks, D. Ren, 2018, Journal of the American Society for Mass Spectrometry.

Elucidation of Degradants in Acidic Peak of Cation Exchange Chromatography in an IgG1 Monoclonal Antibody Formed on Long-Term Storage in a Liquid Formulation

Gang Xiao, P. Bondarenko, D. Ren, 2011, Pharmaceutical Research.

Screening and sequencing of glycated proteins by neutral loss scan LC/MS/MS method.

P. Bondarenko, D. Ren, H. Gadgil, 2007, Analytical chemistry.

Assignment of backbone 1H, 13C and 15N resonances of human IgG1 Fc (51.4 kDa)

D. Brems, D. Ren, Dingjiang Liu, 2007, Biomolecular NMR assignments.

Protein isoaspartate methyltransferase-mediated 18O-labeling of isoaspartic acid for mass spectrometry analysis.

D. Ren, J. Cheetham, Wenqin Ni, 2012, Analytical chemistry.

A high-resolution multi-attribute method for product characterization, process characterization, and quality control of therapeutic proteins.

D. Ren, C. Goudar, M. Ricci, 2022, Analytical biochemistry.

Enabling development, manufacturing, and regulatory approval of biotherapeutics through advances in mass spectrometry.

I. Apostol, P. Bondarenko, Zhongqi Zhang, 2021, Current opinion in biotechnology.

Assignment of 1H, 13C and 15N resonances of the reduced human IgG1 CH3 domain

M. Matsumura, D. Brems, D. Ren, 2007, Biomolecular NMR assignments.

Structure and stability changes of human IgG1 Fc as a consequence of methionine oxidation.

Da Ren, D. Brems, D. Ren, 2008, Biochemistry.

Reversed-phase liquid chromatography-mass spectrometry of site-specific chemical modifications in intact immunoglobulin molecules and their fragments.

Gang Xiao, P. Bondarenko, D. Ren, 2008, Journal of chromatography. A.

Advancing Mass Spectrometry Technology in cGMP Environments.

Da Ren, D. Ren, 2020, Trends in biotechnology.

Chemical modifications of therapeutic proteins induced by residual ethylene oxide.

Zhongqi Zhang, Da Ren, P. Bondarenko, 2015, Journal of pharmaceutical sciences.

Reversed-phase liquid chromatography of immunoglobulin G molecules and their fragments with the diphenyl column.

D. Brems, P. Bondarenko, D. Ren, 2007, Journal of chromatography. A.

Scientific Best Practices for Primary Sequence Confirmation and Sequence Variant Analysis in the Development of Therapeutic Proteins.

Jason C Rouse, Da Ren, Anders Lund, 2020, Journal of pharmaceutical sciences.

Interactions between Therapeutic Proteins and Acrylic Acid Leachable

Yasser Nashed-Samuel, Da Ren, Dengfeng Liu, 2012, PDA Journal of Pharmaceutical Science and Technology.

Elucidation of Degradants in Acidic Peak of Cation Exchange Chromatography in an IgG1 Monoclonal Antibody Formed on Long-Term Storage in a Liquid Formulation

Da Ren, Gang Xiao, P. Bondarenko, 2011, Pharmaceutical Research.