J. Lawler

J. Lawler, Jennifer N. Sims, 2015, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

Crystal structure of the TSP-1 type 1 repeats

A. Joachimiak, Rongguang Zhang, K. Tan, 2002, The Journal of cell biology.

Structural and functional heterogeneity of alpha spectrin mutations involving the spectrin heterodimer self-association site: relationships to hematologic expression of homozygous hereditary elliptocytosis and hereditary pyropoikilocytosis.

J. Lawler, B. Alter, J. Prchal, 1990, Blood.

Severe hemolysis and red cell fragmentation caused by the combination of a spectrin mutation with a thrombotic microangiopathy

J. Moake, J. Lawler, H. Jacob, 1989, American journal of hematology.

Spectrin-alpha I/61: a new structural variant of alpha-spectrin in a double-heterozygous form of hereditary pyropoikilocytosis.

J. Lawler, J. Prchal, R. Moore, 1988, Blood.

Sp all65: A New Variant of the a Subunit of Spectrin in Hereditary Elliptocytosis

J. Lawler, T. Coetzer, H. Jacob, 1985 .

Molecular heterogeneity of hereditary pyropoikilocytosis: identification of a second variant of the spectrin alpha-subunit

J. Lawler, J. Prchal, Shih-Chun Liu, 1983 .

Partial ankyrin and spectrin deficiency in severe, atypical hereditary spherocytosis.

J. Lawler, J. Prchal, S. Liu, 1988, The New England journal of medicine.

The evolution of the thrombospondin gene family

Mark Duquette, Temple F. Smith, J. Lawler, 1993, Journal of Molecular Evolution.

The thrombospondin-4 gene

G. Newton, N. Copeland, D. Gilbert, 1999, Mammalian Genome.

Characterization of Human Thrombospondin-4 (*)

J. Lawler, Laura Derick, M. Duquette, 1995, The Journal of Biological Chemistry.

Original Paper Tumour Suppressor Genes and Angiogenesis: the Role of 7P53 in Fibroblasts

N. Bouck, J. Lawler, V. Stellmach, 1996 .

The crystal structure of the signature domain of cartilage oligomeric matrix protein: implications for collagen, glycosaminoglycan and integrin binding

A. Joachimiak, K. Tan, J. Lawler, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Normalizing Tumor Vasculature to Reduce Hypoxia, Enhance Perfusion, and Optimize Therapy Uptake

J. Lawler, J. Petrik, M. Pereira, 2021, Cancers.

Observation of a High Molecular Weight Platelet Protein Released by Thrombin

J. Lawler, F. Chao, P. H. Fang, 1977, Thrombosis and Haemostasis.

Physical characterization of platelet thrombospondin.

J. Lawler, S. Margossian, H. Slayter, 1981, The Journal of biological chemistry.

The release of heparin binding peptides from platelet thrombospondin by proteolytic action of thrombin, plasmin and trypsin.

J. Lawler, H. Slayter, 1981, Thrombosis research.

ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer

J. Lawler, J. Henkin, J. Petrik, 2009, Molecular Cancer Therapeutics.

Complete amino acid sequence and homologies of human erythrocyte membrane protein band 4.2.

D. Speicher, J. Lawler, C. M. Cohen, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Heparin-induced cis- and trans-Dimerization Modes of the Thrombospondin-1 N-terminal Domain*

A. Joachimiak, K. Tan, J. Lawler, 2008, Journal of Biological Chemistry.

Endothelial Cell Behavior Is Determined by Receptor Clustering Induced by Thrombospondin-1

J. Lawler, J. Petrik, V. Morandi, 2021, Frontiers in Cell and Developmental Biology.

Thrombospondin-1 in a Murine Model of Colorectal Carcinogenesis

S. Chittur, J. Lawler, Bhumi Patel, 2015, PloS one.

Retention of cartilage oligomeric matrix protein (COMP) and cell death in redifferentiated pseudoachondroplasia chondrocytes.

K. Daniels, J. Lawler, J. Hecht, 1998, Matrix biology : journal of the International Society for Matrix Biology.

Localization of thrombospondin, CD36 and CD51 during prenatal development of the human mammary gland.

N. Bertin, P. Delmas, C. Péchoux, 1994, Differentiation; research in biological diversity.

Latency Associated Peptide Has In Vitro and In Vivo Immune Effects Independent of TGF-β1

C. Orosz, N. Flavahan, J. Lawler, 2008, PloS one.

Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations

C. Glass, R. Shenkar, I. Awad, 2017, The Journal of experimental medicine.

Plasmodium falciparum-infected erythrocyte adhesion to the type 3 repeat domain of thrombospondin-1 is mediated by a modified band 3 protein.

I. Sherman, J. Lawler, S. Eda, 1999, Molecular and biochemical parasitology.

Inhibition of Tie-2 Signaling Induces Endothelial Cell Apoptosis, Decreases Akt Signaling and Induces Endothelial Cell Expression of the Endogenous Anti-Angiogenic Molecule, Thrombospondin-1

D. Voskas, J. Lawler, L. Benjamin, 2004, Cancer biology & therapy.

The structure of the Ca2+-binding, glycosylated F-spondin domain of F-spondin - A C2-domain variant in an extracellular matrix protein

K. Tan, J. Lawler, 2011, BMC Structural Biology.

The effect of ultraviolet light on platelets: platelet activation and inhibition of thrombin-mediated functions.

J. Lawler, F. Chao, P. H. Fang, 1979, Thrombosis research.

Immunolocalization of thrombospondin-1 in human atherosclerotic and restenotic arteries.

J. Isner, J. Lawler, R. Riessen, 1998, American heart journal.

The C-terminal domain of thrombospondin-1 induces vascular smooth muscle cell chemotaxis.

V. Gahtan, J. Lawler, B. Sumpio, 2001, Journal of vascular surgery.

The crystal structure of the heparin-binding reelin-N domain of f-spondin.

K. Tan, J. Lawler, Jia-huai Wang, 2008, Journal of molecular biology.

Activation of Platelet-transforming Growth Factor β-1 in the Absence of Thrombospondin-1*

A. Ludlow, J. Lawler, G. Brunner, 2000, The Journal of Biological Chemistry.

The crystal structure of the signature domain of cartilage oligomeric matrix protein.

K. Tan, J. Lawler, 2009 .

C-Mannosylation and O-Fucosylation of the Thrombospondin Type 1 Module*

B. Maček, J. Hofsteenge, J. Peter-Katalinic, 2001, The Journal of Biological Chemistry.

Extracellular matrix: the thrombospondin family.

J. Lawler, J. Adams, 1993, Current biology : CB.

Thrombospondins: from structure to therapeutics

J. Lawler, D. Mosher, C. Carlson, 2008, Cellular and Molecular Life Sciences.

Vascular response to intra-arterial injury in the thrombospondin-1 null mouse.

J. Lawler, E. Davis, K. A. Leonard, 2007, Journal of molecular and cellular cardiology.

The thrombospondin-1 N700S polymorphism is associated with early myocardial infarction without altering von Willebrand factor multimer size.

Flora Peyvandi, Diego Ardissino, Luisa Bernardinelli, 2006, Blood.

Falciparum malaria parasitized erythrocytes bind to a carboxy-terminal thrombospondin fragment and not the amino-terminal heparin-binding region.

J. Lawler, D. Roberts, S. Spitalnik, 1990, Molecular and biochemical parasitology.

Thrombospondin 1--a regulator of adenoma growth and carcinoma progression in the APC(Min/+) mouse model.

M. Suckow, J. Lawler, F. Castellino, 2003, Carcinogenesis.

Clinical and laboratory study of two Caucasian families with hereditary pyropoikilocytosis and hereditary elliptocytosis.

L. Peterson, J. Lawler, J. Palek, 1987, American Journal of Clinical Pathology.

Thrombospondins in the tumor microenvironment.

J. Lawler, J. Petrik, Bianca Garlisi, 2023, Seminars in cell & developmental biology.

Integration of genotypic and phenotypic screening reveals molecular mediators of melanoma-stromal interaction.

Peter W. Chen, Majed, Ming-Yu Liu, 2011, Cancer research.

CD 36 associates with CD 9 and integrins on human blood platelets

William Arbuthnot Sir Lane, J. Lawler, E. Vasile, 2001 .

Identification of cell adhesive active sites in the N-terminal domain of thrombospondin-1.

P. Delmas, J. Lawler, P. Clézardin, 1997, The Biochemical journal.

Vascular smooth muscle cell migration induced by domains of thrombospondin-1 is differentially regulated.

V. Gahtan, J. Lawler, K. Maier, 2011, American journal of surgery.

Thrombospondins.

J. Lawler, 2008, Current drug targets.

Integration of pro- and anti-angiogenic signals by endothelial cells

J. Lawler, S. Kazerounian, 2017, Journal of Cell Communication and Signaling.

The tyrosine kinase inhibitor lenvatinib inhibits anaplastic thyroid carcinoma growth by targeting pericytes in the tumor microenvironment.

C. Nucera, J. Lawler, A. Nazarian, 2023, Thyroid : official journal of the American Thyroid Association.

Hemin-mediated dissociation of erythrocyte membrane skeletal proteins.

J. Lawler, J. Palek, S. Zhai, 1985, The Journal of biological chemistry.

BRAF(V600E) and microenvironment in thyroid cancer: a functional link to drive cancer progression.

C. Nucera, J. Lawler, S. Parangi, 2011, Cancer research.

The BRAFV600E mutation: what is it really orchestrating in thyroid cancer?

C. Nucera, J. Lawler, S. Parangi, 2010, Oncotarget.

A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR.

R. Khosravi‐Far, J. Lawler, B. Ren, 2009, Cancer Research.

The interaction of Thrombospondins with extracellular matrix proteins

K. Tan, J. Lawler, 2009, Journal of Cell Communication and Signaling.

Molecular basis for the regulation of angiogenesis by thrombospondin-1 and -2.

J. Lawler, P. Lawler, 2012, Cold Spring Harbor perspectives in medicine.

Masking epistasis between MYC and TGF-β pathways in antiangiogenesis-mediated colon cancer suppression.

A. Bass, P. Raman, J. Lawler, 2014, Journal of the National Cancer Institute.

A novel orthotopic mouse model of human anaplastic thyroid carcinoma.

C. Nucera, J. Lawler, S. Parangi, 2009, Thyroid : official journal of the American Thyroid Association.

Antiangiogenic Variant of TSP-1 Targets Tumor Cells in Glioblastomas.

K. Shah, J. Lawler, Irina Nesterenko, 2024, Molecular therapy : the journal of the American Society of Gene Therapy.