S. Plowman

发表

Galectin-1 is a novel structural component and a major regulator of h-ras nanoclusters.

J. Hancock, Liron Belanis, S. Plowman, 2008, Molecular biology of the cell.

Plasma membrane nanoswitches generate high-fidelity Ras signal transduction

Tianhai Tian, Robert G. Parton, Angus Harding, 2007, Nature Cell Biology.

Activation of the MAPK module from different spatial locations generates distinct system outputs.

Sarah J. Plowman, J. Hancock, S. Plowman, 2008, Molecular biology of the cell.

A novel switch region regulates H‐ras membrane orientation and signal output

J Andrew McCammon, Daniel Abankwa, Robert G Parton, 2008, The EMBO journal.

K-ras nanoclustering is subverted by overexpression of the scaffold protein galectin-3.

Tianhai Tian, Nicholas Ariotti, T. Tian, 2008, Cancer research.

Mathematical modeling of K-Ras nanocluster formation on the plasma membrane.

T. Tian, J. Hancock, S. Plowman, 2010, Biophysical journal.

Mutationally activated K-ras 4A and 4B both mediate lung carcinogenesis.

W. Kolch, O. Sansom, S. Hagan, 2008, Experimental cell research.

The Anti-inflammatory Drug Indomethacin Alters Nanoclustering in Synthetic and Cell Plasma Membranes*

J. Hancock, S. Plowman, L. Lichtenberger, 2010, The Journal of Biological Chemistry.

H-Ras Nanocluster Stability Regulates the Magnitude of MAPK Signal Output

Sarah J. Plowman, Hong Liang, J. Hancock, 2010, PloS one.

Individual Palmitoyl Residues Serve Distinct Roles in H-Ras Trafficking, Microlocalization, and Signaling

J. Hancock, Y. Henis, S. Plowman, 2005, Molecular and Cellular Biology.

The K-Ras 4A isoform promotes apoptosis but does not affect either lifespan or spontaneous tumor incidence in aging mice.

D. Harrison, M. Arends, S. Plowman, 2006, Experimental cell research.

K-ras proto-oncogene exhibits tumor suppressor activity as its absence promotes tumorigenesis in murine teratomas.

M. Arends, S. Plowman, D. Brooks, 2003, Molecular cancer research : MCR.

H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton

Robert G Parton, J. Hancock, S. Plowman, 2005, Proceedings of the National Academy of Sciences of the United States of America.

While K-ras Is Essential for MouseDevelopment, Expression of the K-ras 4A Splice VariantIsDispensable

D. Harrison, M. Arends, D. Melton, 2003, Molecular and Cellular Biology.

K-ras 4A and 4B are co-expressed widely in human tissues, and their ratio is altered in sporadic colorectal cancer.

D. Harrison, M. Arends, S. Plowman, 2006, Journal of experimental & clinical cancer research : CR.

Ras signaling from plasma membrane and endomembrane microdomains.

J. Hancock, S. Plowman, 2005, Biochimica et biophysica acta.

Cholesterol‐Sensitive Cdc42 Activation Regulates Actin Polymerization for Endocytosis via the GEEC Pathway

S. Mayor, J. Hancock, S. Plowman, 2007, Traffic.

Raf Inhibitors Target Ras Spatiotemporal Dynamics

A. Kusumi, S. Heidorn, Kwang-jin Cho, 2012, Current Biology.

Electrostatic Interactions Positively Regulate K-Ras Nanocluster Formation and Function

J. Hancock, S. Plowman, R. Parton, 2008, Molecular and Cellular Biology.

Nonsteroidal Anti-inflammatory Drugs Alter the Spatiotemporal Organization of Ras Proteins on the Plasma Membrane*

Yong Zhou, Kwang-jin Cho, J. Hancock, 2012, The Journal of Biological Chemistry.

Epidermal Growth Factor Receptor Activation Remodels the Plasma Membrane Lipid Environment To Induce Nanocluster Formation

Hong Liang, J. Hancock, S. Plowman, 2010, Molecular and Cellular Biology.

Mtx2 directs zebrafish morphogenetic movements during epiboly by regulating microfilament formation.

A. Perkins, J. Hancock, S. Plowman, 2008, Developmental biology.

A novel switch region regulates H‐ras membrane orientation and signal output

A. Gorfe, J. Hancock, S. Plowman, 2008, The EMBO journal.