P. Kavathas

R. Herbst, A. Chiang, D. Zelterman, 2018, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Transfer of cloned human class I major histocompatibility complex genes into HLA mutant human lymphoblastoid cells

H. Orr, B. Koller, R. Demars, 1986, Molecular and cellular biology.

Molecular analysis of protein interactions mediating the function of the cell surface protein CD8

L. Devine, P. Kavathas, 1999, Immunologic research.

Location of the epitope for an anti-CD8alpha antibody 53.6.7 which enhances CD8alpha-MHC class I interaction indicates antibody stabilization of a higher affinity CD8 conformation.

S. Jameson, L. Devine, P. Kavathas, 2004, Immunology letters.

Adaptive Immunity: Effector Functions, Regulation, and Vaccination

P. Krause, P. Kavathas, N. Ruddle, 2019, Immunoepidemiology.

Human CD8α expression in NK cells but not cytotoxic T cells of transgenic mice

P. Kavathas, J. Mcneish, J. Hanke, 1996 .

Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions.

G. Nolan, H. Nakauchi, L. Herzenberg, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Stable transformation of mouse L cells for human membrane T-cell differentiation antigens, HLA and beta 2-microglobulin: selection by fluorescence-activated cell sorting.

L. Herzenberg, P. Kavathas, 1983, Proceedings of the National Academy of Sciences of the United States of America.

A non-class I MHC intestinal epithelial surface glycoprotein, gp180, binds to CD8.

L. Devine, P. Kavathas, L. Toy, 2002, Clinical immunology.

Amplification of a gene coding for human T-cell differentiation antigen

L. Herzenberg, P. Kavathas, 1983, Nature.

Repetitive Alu elements form a cruciform structure that regulates the function of the human CD8 alpha T cell-specific enhancer.

P. Kavathas, J. Hanke, J. Hambor, 1995, Journal of molecular biology.

Use of HLA loss mutants to analyse the structure of the human major histocompatibility complex

H. Orr, H. Ploegh, J. Strominger, 1982, Nature.

P. Kavathas, A. Shaw, J. Rose, 1990, Molecular and cellular biology.

P. Kavathas, A. Shaw, K. Amrein, 2022 .

Adaptive Immunity: Antigen Recognition by T and B Lymphocytes

P. Krause, P. Kavathas, N. Ruddle, 2019, Immunoepidemiology.

RepetitiveAluElements form a Cruciform Structure that Regulates the Function of the Human CD8α T Cell-specific En hancer

P. Kavathas, J. Hanke, J. Hambor, 1995 .

SB: a new HLA-linked human histocompatibility gene defined using HLA-mutant cell lines

F. Bach, R. Demars, P. Kavathas, 1981, Nature.

Family studies define a new histocompatibility locus, SB, between HLA-DR and GLO

D. Charmot, P. Kavathas, S. Shaw, 1981, Nature.

Gamma ray-induced loss of expression of HLA and glyoxalase I alleles in lymphoblastoid cells.

F. Bach, R. Demars, P. Kavathas, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Identification and Characterization of an Alu-Containing, T-Cell-Specific Enhancer Located in the Last Intron of the Human CD8ac Gene

P. Kavathas, J. Hanke, E. John, 2022 .

Mapping the Binding Site on CD8β for MHC Class I Reveals Mutants with Enhanced Binding1

L. Devine, P. Kavathas, M. Hodsdon, 2006, The Journal of Immunology.

Molecular Basis for the High Affinity Interaction between the Thymic Leukemia Antigen and the CD8αα Molecule1

E. Reinherz, L. Devine, P. Kavathas, 2005, The Journal of Immunology.

The Complementarity-Determining Region-Like Loops of CD8α Interact Differently with β2-Microglobulin of the Class I Molecules H-2Kb and Thymic Leukemia Antigen, While Similarly with Their α3 Domains1

L. Devine, P. Kavathas, H. Cheroutre, 2002, The Journal of Immunology.

The human T cell antigen Leu-2 (T8) is encoded on chromosome 2

S. Latt, Y. Shiloh, L. Herzenberg, 2004, Human Genetics.

Hemizygous HLA mutants of lymphoblastoid cells: a new cell type for histocompatibility testing.

F. Bach, R. Demars, P. Kavathas, 1980, Human Immunology.

Fluorescence-activated cell sorting of mouse-human hybrid cells aids in locating the gene for the Leu 7 (HNK-1) antigen to human chromosome 11.

L. Herzenberg, P. Kavathas, J. Schröder, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Uric Acid Induces Trophoblast IL‐1β Production Via the Inflammasome: Implications for the Pathogenesis of Preeclampsia

P. Kavathas, E. Norwitz, S. Guller, 2011, American journal of reproductive immunology.

Epstein-Barr virus shuttle vector for stable episomal replication of cDNA expression libraries in human cells

P. Kavathas, R. Margolskee, P. Berg, 1988, Molecular and cellular biology.

A new variant glyoxalase I allele that is readily detectable in stimulated lymphocytes and lymphoblastoid cell lines but not in circulating lymphocytes or erythrocytes.

R. Demars, P. Kavathas, 1981, American journal of human genetics.

Severe Tryptophan Starvation Blocks Onset of Conventional Persistence and Reduces Reactivation of Chlamydia trachomatis

P. Cresswell, P. Kavathas, Ralf M. Leonhardt, 2007, Infection and Immunity.

Orientation of the Ig Domains of CD8αβ Relative to MHC Class I

L. Devine, P. Kavathas, Jiaren Sun, 1999, The Journal of Immunology.

Transfection and cloning of genes for membrane antigens using the FACS

L. Herzenberg, S. Alberti, P. Kavathas, 1984, Medical oncology and tumor pharmacotherapy.

Human CD8β, But Not Mouse CD8β, Can Be Expressed in the Absence of CD8α as a ββ Homodimer1

L. Devine, P. Kavathas, L. Kieffer, 2000, The Journal of Immunology.

A Role for Uric Acid and the Nalp3 Inflammasome in Antiphospholipid Antibody-Induced IL-1β Production by Human First Trimester Trophoblast

J. Brosens, P. Kavathas, J. Salmon, 2013, PloS one.

Human CD8oc expression in NK cells but not cytotoxic T cells of transgenic mice

P. Kavathas, J. Mcneish, J. Hanke, 2004 .

Nod1, but not the ASC inflammasome, contributes to induction of IL-1β secretion in human trophoblasts after sensing of Chlamydia trachomatis

P. Kavathas, M. Mulla, V. Abrahams, 2012, Mucosal Immunology.

The role of charge and multiple faces of the CD8 alpha/alpha homodimer in binding to major histocompatibility complex class I molecules: support for a bivalent model.

D. Leahy, P. Kavathas, P. Giblin, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Appropriate developmental expression of human CD8 beta in transgenic mice.

P. Kavathas, J. Hanke, L. Kieffer, 1997, Journal of immunology.

Post-transcriptional regulation associated with control of human CD8A expression of CD4+ T cells

P. Kavathas, M. Gao, M. Walz, 1996, Immunogenetics.

Molecular cloning ofLyt-2, amembraneglycoprotein marking a subset ofmouseTlymphocytes: Molecular homology toitshuman counterpart, Leu-2/T8, andtoimmunoglobulin variable regions

G. Nolan, H. Nakauchi, P. Kavathas, 1985 .

Lymphocyte subsets in Sjogren's syndrome: a quantitative analysis using monoclonal antibodies and the fluorescence-activated cell sorter.

L. Herzenberg, N. Miyasaka, P. Kavathas, 1983, Journal of clinical & laboratory immunology.

Isolation of the gene encoding the human T-lymphocyte differentiation antigen Leu-2 (T8) by gene transfer and cDNA subtraction.

V. Sukhatme, L. Herzenberg, P. Kavathas, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Identification of a Candidate Regulatory Region in the Human CD8 Gene Complex by Colocalization of DNase I Hypersensitive Sites and Matrix Attachment Regions Which Bind SATB1 and GATA-31

J. Greally, P. Kavathas, T. Kohwi-Shigematsu, 2002, The Journal of Immunology.

SATB 1 and GATA-3 and Matrix Attachment Regions Which Bind SitesColocalization of DNase I Hypersensitive Gene Complex by CD 8 Region in the Human Identification of a Candidate Regulatory

J. Greally, P. Kavathas, T. Kohwi-Shigematsu, 2002 .

A dormant TIL phenotype defines non-small cell lung carcinomas sensitive to immune checkpoint blockers

R. Herbst, D. Zelterman, D. Rimm, 2018, Nature Communications.

Identification and characterization of an Alu-containing, T-cell-specific enhancer located in the last intron of the human CD8 alpha gene

P. Kavathas, J. Hanke, J. Hambor, 1993, Molecular and cellular biology.

Mutations in CD8 that affect interactions with HLA class I and monoclonal anti-CD8 antibodies

P. Kavathas, S. Sanders, R. Fox, 1991, The Journal of experimental medicine.

A modified cell surface marker gene for transgenic animal studies.

P. Kavathas, L. Kieffer, 1998, Nucleic acids research.

Amplification and Molecular Cloning of Transfected Genes

P. Kavathas, 1985 .

Chlamydia trachomatis Infection Modulates Trophoblast Cytokine/Chemokine Production1

P. Kavathas, M. Mulla, V. Abrahams, 2009, The Journal of Immunology.

Chlamydia trachomatis Infection Modulates Trophoblast Cytokine / Chemokine Production 1

P. Kavathas, M. Mulla, V. Abrahams, 2009 .

Spatial Analysis and Clinical Significance of HLA Class-I and Class-II Subunit Expression in Non–Small Cell Lung Cancer

D. Rimm, K. Schalper, K. Syrigos, 2021, Clinical Cancer Research.

Innate Immunity: Recognition and Effector Functions

P. Krause, P. Kavathas, N. Ruddle, 2019, Immunoepidemiology.

Immunoepidemiology

P. Krause, P. Kavathas, N. Ruddle, 2019 .

Association of CD8 with p56lck is required for early T cell signalling events.

P. Kavathas, J. Ledbetter, N. J. Chalupny, 1991, The EMBO journal.

Disorders of the Immune System

P. Krause, P. Kavathas, N. Ruddle, 2019, Immunoepidemiology.

Activation of T cells by H-2 factors in the graft-vs-host reaction.

F. Bach, P. Kavathas, W. Elkins, 1973, Transplantation proceedings.

Differential Expression of the Human CD8β Splice Variants and Regulation of the M-2 Isoform by Ubiquitination1

L. Devine, P. Kavathas, J. Dobbins, 2008, The Journal of Immunology.

Interplay between TCR Affinity and Necessity of Coreceptor Ligation: High-Affinity Peptide-MHC/TCR Interaction Overcomes Lack of CD8 Engagement 1

Paula Kavathas, Robert Maile, Edward J. Collins, 2003, The Journal of Immunology.

High-Affinity Peptide-MHC / TCR Interaction Necessity of Coreceptor Ligation : Interplay between TCR Affinity and

J. Frelinger, P. Kavathas, R. Maile, 2003 .

Immunoepidemiology of Selected Components of the Innate and Adaptive Immune Systems

P. Kavathas, N. Ruddle, 2019, Immunoepidemiology.

A secreted form of the human lymphocyte cell surface molecule CD8 arises from alternative splicing.

P. Kavathas, J. Ledbetter, P. Giblin, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Molecular basis for the high affinity interaction between the thymic leukemia antigen and the CD8alphaalpha molecule.

E. Reinherz, L. Devine, P. Kavathas, 2005, Journal of immunology.

The Golgi-Associated Protein p115 Mediates the Secretion of Macrophage Migration Inhibitory Factor1

J. Bernhagen, L. Leng, R. Bucala, 2009, The Journal of Immunology.

Interaction between CD8 and major histocompatibility complex (MHC) class I mediated by multiple contact surfaces that include the alpha 2 and alpha 3 domains of MHC class I

J. Sun, D. Leahy, P. Kavathas, 1995, The Journal of experimental medicine.

Increased efficiency of folding and peptide loading of mutant MHC class I molecules

T. Beißbarth, P. Kavathas, Jiaren Sun, 2000, European journal of immunology.

Human CD8 beta, but not mouse CD8 beta, can be expressed in the absence of CD8 alpha as a beta beta homodimer.

L. Devine, P. Kavathas, L. Kieffer, 2000, Journal of immunology.

A dormant TIL phenotype defines non-small cell lung carcinomas sensitive to immune checkpoint blockers

R. Herbst, D. Zelterman, D. Rimm, 2018, Nature Communications.

Functional importance of the cyclic AMP response element-like decamer motif in the CD8 alpha promoter.

P. Kavathas, M. Gao, 1993, Journal of immunology.

Comparison of the roles of CD8 alpha alpha and CD8 alpha beta in interaction with MHC class I.

J. Sun, P. Kavathas, 1997, Journal of immunology.

Orientation of the Ig domains of CD8 alpha beta relative to MHC class I.

J. Sun, L. Devine, P. Kavathas, 1999, Journal of immunology.

Gender inequity: challenging business as usual

P. Kavathas, L. Soong, 2001, Nature Immunology.

The Human CD8β M-4 Isoform Dominant in Effector Memory T Cells Has Distinct Cytoplasmic Motifs That Confer Unique Properties

P. Kavathas, J. Riley, Sunil Martin, 2013, PloS one.

Extensive T-Cell Epitope Repertoire Sharing among Human Proteome, Gastrointestinal Microbiome, and Pathogenic Bacteria: Implications for the Definition of Self

P. Kavathas, N. Gascoigne, R. Bremel, 2015, Front. Immunol..

Interaction Between CD 8 and Major Histocompatibility Complex ( MHC ) Class I Mediated by Multiple Contact Surfaces that Include the oL 2 and oL 3 Domains of MHC Class I By

D. Leahy, P. Kavathas, Jiaren Sun, 2003 .