P. Ofek

发表

Reverting the molecular fingerprint of tumor dormancy as a therapeutic strategy for glioblastoma

E. Ruppin, Z. Ram, J. Lee, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Amphiphilic nanocarrier-induced modulation of PLK1 and miR-34a leads to improved therapeutic response in pancreatic cancer

Eytan Ruppin, Iris Barshack, Joo Sang Lee, 2018, Nature Communications.

Cell cycle regulation and p53 activation by protein phosphatase 2C alpha.

M. Oren, P. Ofek, S. Lavi, 2003, The Journal of biological chemistry.

siRNA transfection by dendritic core-shell nanocarriers.

R. Haag, P. Ofek, R. Satchi‐Fainaro, 2010, Journal of controlled release : official journal of the Controlled Release Society.

MCP-1/CCR2 axis inhibition sensitizes the brain microenvironment against melanoma brain metastasis progression

E. Ruppin, I. Slutsky, I. Barshack, 2022, JCI insight.

Genomic alterations drive brain metastases formation in colorectal cancer: The role of IRS2

E. Sokol, P. Ofek, E. Yeini, 2022, bioRxiv.

Functionalized nanogels carrying an anticancer microRNA for glioblastoma therapy.

R. Haag, G. Tiram, P. Ofek, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Administration, distribution, metabolism and elimination of polymer therapeutics.

G. Tiram, Shiran Ferber, P. Ofek, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Interfering cancer with polymeric siRNA nanomedicines.

G. Tiram, P. Ofek, R. Satchi‐Fainaro, 2014, Journal of biomedical nanotechnology.

Interfering Cancer with Polymeric siRNA Nanocarriers

G. Tiram, P. Ofek, R. Satchi‐Fainaro, 2013 .

Targeting Angiogenesis-Dependent Calcified Neoplasms Using Combined Polymer Therapeutics

P. Ofek, R. Satchi‐Fainaro, J. Kopeček, 2009, PloS one.

Proteogenomics of glioblastoma associates molecular patterns with survival

N. Shomron, T. Geiger, P. Ofek, 2020, medRxiv.

P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression

S. Reich-Zeliger, Z. Ram, A. Madi, 2021, Nature Communications.

Targeting Glioblastoma: Advances in Drug Delivery and Novel Therapeutic Approaches

G. Tiram, P. Ofek, A. Eldar-Boock, 2020, Advanced Therapeutics.

Meet me halfway: Are in vitro 3D cancer models on the way to replace in vivo models for nanomedicine development?

P. Ofek, Adva Krivitsky, R. Satchi‐Fainaro, 2021, Advanced drug delivery reviews.

A novel antitumor prodrug platform designed to be cleaved by the endoprotease legumain.

P. Ofek, R. Satchi‐Fainaro, A. Many, 2009, Bioconjugate chemistry.

Sulfonated Amphiphilic Poly(α)glutamate Amine—A Potential siRNA Nanocarrier for the Treatment of Both Chemo-Sensitive and Chemo-Resistant Glioblastoma Tumors

A. Madi, P. Ofek, E. Yeini, 2021, Pharmaceutics.

Restoring the oncosuppressor activity of microRNA-34a in glioblastoma using a polyglycerol-based polyplex

Z. Ram, R. Haag, G. Tiram, 2016, Nanomedicine : nanotechnology, biology, and medicine.

Cell Cycle Regulation and p53 Activation by Protein Phosphatase 2Cα*

M. Oren, P. Ofek, S. Lavi, 2003, The Journal of Biological Chemistry.

Angiogenesis regulation by nanocarriers bearing RNA interference☆

G. Tiram, P. Ofek, R. Satchi‐Fainaro, 2017, Advanced drug delivery reviews.

Successful intracranial delivery of trastuzumab by gene‐therapy for treatment of HER2‐positive breast cancer brain metastases

Shay Sherbo, Atar Liran, P. Ofek, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Rational Design of Multifunctional Polymer Therapeutics for Cancer Theranostics

P. Ofek, A. Eldar-Boock, R. Satchi‐Fainaro, 2010 .

An inducible system to study the growth arrest properties of protein phosphatase 2C.

P. Ofek, S. Lavi, D. Ben-Meir, 2003, Methods in enzymology.

Identification of Dormancy-Associated MicroRNAs for the Design of Osteosarcoma-Targeted Dendritic Polyglycerol Nanopolyplexes.

B. Kerem, N. Shomron, I. Barshack, 2016, ACS nano.

Co-targeting the tumor endothelium and P-selectin-expressing glioblastoma cells leads to a remarkable therapeutic outcome

E. Ruppin, Z. Ram, Noam Auslander, 2017, eLife.

Amphiphilic nanocarrier-induced modulation of PLK1 and miR-34a leads to improved therapeutic response in pancreatic cancer

E. Ruppin, I. Barshack, J. Lee, 2018, Nature Communications.

Amphiphilic poly(α)glutamate polymeric micelles for systemic administration of siRNA to tumors.

G. Tiram, P. Ofek, Adva Krivitsky, 2018, Nanomedicine : nanotechnology, biology, and medicine.

In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers

R. Haag, P. Ofek, M. Calderón, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Development of PEGylated doxorubicin-E-[c(RGDfK)2] conjugate for integrin-targeted cancer therapy

P. Ofek, A. Eldar-Boock, R. Satchi‐Fainaro, 2011 .

Deoxyhypusine hydroxylase: A novel therapeutic target differentially expressed in short‐term vs long‐term survivors of glioblastoma

N. Shomron, Z. Ram, T. Hyde, 2023, International journal of cancer.

Abstract 2716: P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression

S. Reich-Zeliger, Z. Ram, A. Madi, 2021, Tumor Biology.