S. Elledge

发表

ATM-Independent Manner Mutated (ATM)-Dependent and an Apoptosis in both an Ataxia Telangiectasia Chk2 Is a Tumor Suppressor That Regulates

P. Jeggo, S. Lowe, R. Bristow, 2014 .

Oppositely imprinted genes p57(Kip2) and igf2 interact in a mouse model for Beckwith-Wiedemann syndrome.

M. Cleary, S. Tilghman, S. Elledge, 1999, Genes & development.

Multiple genetic loci within 11p15 defined by Beckwith-Wiedemann syndrome rearrangement breakpoints and subchromosomal transferable fragments.

A. Feinberg, D. Schlessinger, P. Taillon-Miller, 1995, Proceedings of the National Academy of Sciences of the United States of America.

ATR and ATRIP: Partners in Checkpoint Signaling

Jun Qin, S. Elledge, D. Cortez, 2001, Science.

Chk1 is haploinsufficient for multiple functions critical to tumor suppression.

J. Rosen, Qinghua Liu, S. Elledge, 2004, Cancer cell.

Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 and p53

C. Deng, T. Ried, M.-H. Lee, 2010, Oncogene.

Low frequency of p57KIP2 mutation in Beckwith-Wiedemann syndrome.

A. Feinberg, S. Elledge, M. DeBaun, 1997, American journal of human genetics.

A Role for the Deubiquitinating Enzyme USP28 in Control of the DNA-Damage Response

T. Mak, Dong Zhang, S. Elledge, 2006, Cell.

The two faces of BRCA2, a FANCtastic discovery.

G. Stewart, S. Elledge, 2002, Molecular cell.

BRCA2 Enters the Fray

S. Elledge, John H. Wilson, 2002, Science.

Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination

E. Zackai, J. Massagué, K. Gripp, 2000, Nature Genetics.

Chk2 Is a Tumor Suppressor That Regulates Apoptosis in both an Ataxia Telangiectasia Mutated (ATM)-Dependent and an ATM-Independent Manner

P. Jeggo, S. Lowe, R. Bristow, 2002, Molecular and Cellular Biology.

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma

W. Cavenee, F. Furnari, D. Kozono, 2014, Oncotarget.

ATM – Chk 2 – p 53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca 1 deficiency

Noboru, Motoyama, X. Coumoul, 2013 .

Cross-talk between Chk1 and Chk2 in double-mutant thymocytes

T. Mak, A. Hirao, S. Elledge, 2007, Proceedings of the National Academy of Sciences.

Renal-retinal ciliopathy gene Sdccag8 regulates DNA damage response signaling.

S. Bekker-Jensen, T. Hurd, A. Kispert, 2014, Journal of the American Society of Nephrology : JASN.

SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication

V. Mootha, S. Elledge, D. Hung, 2021, Nature Communications.

Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication.

Bing Xia, Weidong Wang, Weidong Wang, 2009, Molecular cell.

Cancer. BRCA2 enters the fray.

S. Elledge, John H. Wilson, 2002, Science.