J. Grierson

发表

Effect of p53 activation on cell growth, thymidine kinase-1 activity, and 3'-deoxy-3'fluorothymidine uptake.

K. Krohn, J. Schwartz, R. Jordan, 2004, Nuclear medicine and biology.

A radiosynthesis of fluorine-18 fluoromisonidazole.

C. Mathis, K. Krohn, J. Rasey, 1989, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Tumor Hypoxia Imaging with [F-18] Fluoromisonidazole Positron Emission Tomography in Head and Neck Cancer

David L. Schwartz, Kenneth A. Krohn, J. O'Sullivan, 2006, Clinical Cancer Research.

Imaging proliferation in vivo with [F-18]FLT and positron emission tomography

Otto Muzik, O. Muzik, A. Shields, 1998, Nature Medicine.

Kinetic modeling of 3'-deoxy-3'-fluorothymidine in somatic tumors: mathematical studies.

Mark Muzi, Hubert Vesselle, David A Mankoff, 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Kinetic analysis of 3'-deoxy-3'-fluorothymidine PET studies: validation studies in patients with lung cancer.

Mark Muzi, Hubert Vesselle, David A Mankoff, 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Evaluation of oxygenation status during fractionated radiotherapy in human nonsmall cell lung cancers using [F-18]fluoromisonidazole positron emission tomography.

K L Lindsley, T K Lewellen, M. Graham, 1995, International journal of radiation oncology, biology, physics.

Metabolism of 3'-deoxy-3'-[F-18]fluorothymidine in proliferating A549 cells: validations for positron emission tomography.

M. Muzi, K. Krohn, R. Jordan, 2004, Nuclear medicine and biology.

PET Correlates with Thymidine Kinase 1 Expression: Static and Kinetic Analysis of 18 F-FLT PET Studies in Lung Tumors

H. Vesselle, L. Wiens, J. Rasey, 2011 .

Tumor 3′-Deoxy-3′-18F-Fluorothymidine (18F-FLT) Uptake by PET Correlates with Thymidine Kinase 1 Expression: Static and Kinetic Analysis of 18F-FLT PET Studies in Lung Tumors

H. Vesselle, L. Wiens, J. Rasey, 2011, The Journal of Nuclear Medicine.

A SepPak unit for batch processing serial blood plasma samples for PET

H. Vesselle, L. Wiens, J. Grierson, 2007 .

The Metabolism of [18F]6‐Fluoro‐l‐3,4‐Dihydroxyphenylalanine in the Hooded Rat

E. Mcgeer, J. Grierson, B. Boyes, 1987, Journal of neurochemistry.

Noninvasive detection of hypoxic myocardium using fluorine-18-fluoromisonidazole and positron emission tomography.

M. Graham, T. Lewellen, K. Krohn, 1992, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Tumor Hypoxia Imagingwith [F-18] Fluoromisonidazole Positron EmissionTomography in Head and Neck Cancer

J. O'Sullivan, K. Krohn, J. Grierson, 2006 .

Detection of Proliferation in Gliomas by Positron Emission Tomography Imaging

D. Mankoff, J. Eary, D. Silbergeld, 2006 .

Glypican-3–Targeting F(ab′)2 for 89Zr PET of Hepatocellular Carcinoma

Forrest M Kievit, S. Minoshima, Miqin Zhang, 2014, The Journal of Nuclear Medicine.

Incorporation of A Phosphonium Analogue of Choline Into The Rat Brain as Measured by Magnetic Resonance Spectroscopy

T. Richards, A. Heide, J. Grierson, 1995, Magnetic resonance in medicine.

5-Fluoro-1-(2'-deoxy-2'-fluoro-beta-D-ribofuranosyl) uracil trapping in Morris hepatoma cells expressing the herpes simplex virus thymidine kinase gene.

U. Haberkorn, A. Shields, J. Grierson, 1998, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Kinetics of in vitro decarboxylation and the in vivo metabolism of 2-18F- and 6-18F-fluorodopa in the hooded rat.

M. Häusser, P. Cumming, J. Grierson, 1988, Biochemical pharmacology.

A practical preparative scale synthesis of d/l‐6‐fluorodopa

J. Grierson, M. Adam, 1986 .

Routine synthesis of L-[18F]6-fluorodopa with fluorine-18 acetyl hypofluorite.

B. Pate, J. Grierson, T. Ruth, 1986, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Reaction of [18F]acetyl hypofluorite with derivatives of dihydroxyphenylalanine: Synthesis of l-[18F]6-fluorodopa

J. Grierson, T. Ruth, M. Adam, 1986 .

Development of F-18 Labeled Radiotracers for PET Imaging of Brain Alpha-1 Noradrenergic Receptors: Potential PTSD Vulnerability and Diagnostic Biomarkers

D. Cross, J. Grierson, E. Petrie, 2012 .

Kinetic analysis of 3'-deoxy-3'-18F-fluorothymidine in patients with gliomas.

Mark Muzi, Finbarr O'Sullivan, David A Mankoff, 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

A new synthesis of the labeling precursor for [18F]- fluoromisonidazole

K. Krohn, J. Grierson, T. C. Adamsen, 2005 .

Validation of FLT uptake as a measure of thymidine kinase-1 activity in A549 carcinoma cells.

L. Wiens, J. Schwartz, J. Rasey, 2002, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

A simple quantitative assay for the activity of thymidine kinase 1 in solid tumors.

H. Vesselle, L. Wiens, J. Rasey, 2007, Nuclear medicine and biology.

Toxicology evaluation of radiotracer doses of 3'-deoxy-3'-[18F]fluorothymidine (18F-FLT) for human PET imaging: Laboratory analysis of serial blood samples and comparison to previously investigated therapeutic FLT doses

H. Vesselle, L. Wiens, J. Grierson, 2007, BMC nuclear medicine.

Evaluation of 5'-deoxy-5'-[F-18]fluorothymidine as a tracer of intracellular thymidine phosphorylase activity.

H. Vesselle, L. Wiens, R. Jordan, 2007, Nuclear medicine and biology.

The Role of Imaging in the Development of Oncologic Agents

A. Shields, J. Grierson, P. Ho, 1999, Journal of clinical pharmacology.

Monitoring tumor cell proliferation by targeting DNA synthetic processes with thymidine and thymidine analogs.

K. Krohn, J. Schwartz, R. Jordan, 2003, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Synthesis of -chloro, -bromo, and -iodo a,-unsaturated ketones

C. K. Lau, J. Grierson, E. Piers, 1982 .

Radiosynthesis of 6-[C-11]-D-glucose.

K. Krohn, J. Grierson, J. Link, 1993, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Routine synthesis of carbon-11-carboxyl-labeled L-dopa.

B. Pate, J. Grierson, T. Ruth, 1987, Journal of Nuclear Medicine.

New routes to N-alkylated cyclic sulfamidates.

J. Grierson, T. Tewson, J. Posakony, 2002, The Journal of organic chemistry.

In-situ Preparation of a chemically bonded chiral stationary phase for the separation of aromatic α-amino acid enantiomers

J. Grierson, M. J. Adam, 1985 .

Radiosynthesis of 3'-deoxy-3'-[(18)F]fluorothymidine: [(18)F]FLT for imaging of cellular proliferation in vivo.

A. Shields, J. Grierson, J R Grierson, 2000, Nuclear medicine and biology.

Development of labeled thymidine analogs for imaging tumor proliferation.

A. Shields, J. Grierson, J R Grierson, 1996, Nuclear medicine and biology.

Synthesis and in Vitro Evaluation of 5-Fluoro-6-[(2-Iminopyrrolidin-1-YL)Methyl]Uracil, TPI(F): An Inhibitor of Human Thymidine Phosphorylase (TP)

H. Vesselle, L. Wiens, J. Rasey, 2010, Nucleosides, nucleotides & nucleic acids.

Radiosyntheses of labeled beta-pseudothymidine ([C-11]- and [H-3]methyl) and its biodistribution and metabolism in normal and tumored mice.

A. Shields, J. Grierson, M. Zheng, 1995, Nuclear medicine and biology.

Evaluating 5'-Deoxy-5'-[F-18]fluorothymidine ([F-18]DFT) as a tracer of intracellular thymidine phosphorylase activity

H. Vesselle, L. Wiens, R. Jordan, 2007 .

Utilization of labeled thymidine in DNA synthesis: studies for PET.

J Grierson, A. Shields, K. Krohn, 1990, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[18F]FMISO and [18F]FDG PET imaging in soft tissue sarcomas: correlation of hypoxia, metabolism and VEGF expression

J. Eary, E. Conrad, K. Krohn, 2003, European Journal of Nuclear Medicine and Molecular Imaging.

Evaluation of 18F-annexin V as a PET imaging agent in an animal model of apoptosis.

J. Eary, D. Gibson, J. Tait, 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Production of [F-18]fluoroannexin for imaging apoptosis with PET.

Janet F Eary, Kenneth A Krohn, J. Eary, 2004, Bioconjugate chemistry.

Imaging of hypoxia in human tumors with [F-18]fluoromisonidazole.

T W Griffin, T K Lewellen, M. Graham, 1992, International journal of radiation oncology, biology, physics.

Synthesis of an (iodovinyl)misonidazole derivative for hypoxia imaging.

K. Krohn, J. Rasey, J. Grierson, 1991, Journal of medicinal chemistry.

Carbon-11-thymidine and FDG to measure therapy response.

T K Lewellen, D. Mankoff, M. Graham, 1998, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

FLT: measuring tumor cell proliferation in vivo with positron emission tomography and 3'-deoxy-3'-[18F]fluorothymidine.

Hubert Vesselle, H. Vesselle, J. Grierson, 2007, Seminars in nuclear medicine.

In vivo validation of 3'deoxy-3'-[(18)F]fluorothymidine ([(18)F]FLT) as a proliferation imaging tracer in humans: correlation of [(18)F]FLT uptake by positron emission tomography with Ki-67 immunohistochemistry and flow cytometry in human lung tumors.

Mark Muzi, Hubert Vesselle, D. Wood, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Kinetics of 3'-deoxy-3'-[F-18]fluorothymidine uptake and retention in dogs.

O. Muzik, A. Shields, T. Mangner, 2002, Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.

EHPnet: Bioremediation

H. Vesselle, L. Wiens, J. Grierson, 1996, Environmental Health Perspectives.

Glypican-3–Targeted 89Zr PET Imaging of Hepatocellular Carcinoma

S. Minoshima, Miqin Zhang, M. Yeh, 2014, The Journal of Nuclear Medicine.

PET scanning in dystonia.

M. Palmer, B. Pate, J. Grierson, 1988, Advances in neurology.

Radiolabelled fluoromisonidazole as an imaging agent for tumor hypoxia.

K. Krohn, J. Rasey, J. Grierson, 1989, International journal of radiation oncology, biology, physics.

18F-Fluorothymidine radiation dosimetry in human PET imaging studies.

D. Mankoff, H. Vesselle, M. Muzi, 2003, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Simplified Labeling Approach for Synthesizing 3′-Deoxy-3′-[18F]fluorothymidine ([18F]FLT)

J. R. Grierson, Hans-Jürgen Machulla, M. Piert, 2000 .

Synthesis of 6-(F-18)L-fluoro-dopa using F-18 labelled acetyl hypofluorite

B. Pate, J. Grierson, T. Ruth, 1985 .

Feasibility of imaging pentose cycle glucose metabolism in gliomas with PET: studies in rat brain tumor models.

F. O’Sullivan, M. Graham, M. Muzi, 1997, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Alkylation of 1,5-dimethoxy-1,4-cyclohexadiene. A convenient synthesis of 2-alkyl- and 2-alkenyl-1,3-cyclohexanediones

J. Grierson, E. Piers*, 1977 .

Imaging Hypoxic Myocardium

J. Grierson, G. Martin, J. Caldwell, 1996 .

SYNTHESIS OF β-CHLORO, β-BROMO, AND β-IODO α,β-UNSATURATED KETONES

C. K. Lau, J. Grierson, I. Nagakura, 1982 .