D. Kokkinakis

发表

Multifaceted resistance of gliomas to temozolomide.

S. Finkelstein, S. Schold, D. Bocangel, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Multifaceted Resistance of Gliomas to Temozolomide 1

S. Finkelstein, S. Schold, D. Bocangel, 2002 .

Modulation of cell cycle and gene expression in pancreatic tumor cell lines by methionine deprivation (methionine stress): implications to the therapy of pancreatic adenocarcinoma

D. Kokkinakis, Xiaoyan Liu, Russell Neuner, 2005, Molecular Cancer Therapeutics.

High throughput screening of methylation status of genes in prostate cancer using an oligonucleotide methylation array.

Yan Ping Yu, Jian-Hua Luo, Y. Yu, 2004, Carcinogenesis.

Induction of a step in carcinogenesis that is normally associated with mutagenesis by nonmutagenic concentrations of 5-azacytidine

N. Bouck, D. Kokkinakis, J. Ostrowsky, 1984 .

Regulation of O6-methylguanine-DNA methyltransferase by methionine in human tumour cells.

T. Brent, S. Schold, D. Kokkinakis, 1997, British Journal of Cancer.

Peroxisome proliferator-induced hepatocarcinogenesis: levels of activating and detoxifying enzymes in hepatocellular carcinomas induced by ciprofibrate.

J. Reddy, D. Kokkinakis, M. Rao, 1987, Carcinogenesis.

Sensitization of pancreatic tumor xenografts to carmustine and temozolomide by inactivation of their O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2'-deoxyguanosine.

Mansoor M Ahmed, D. Chendil, D. Kokkinakis, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

High yields of Kras mutations in intraductal papillary mucinous tumors and invasive adenocarcinomas induced by iV-nitroso ( 2-hydroxypropyl ) ( 2-oxopropyl ) amine in the pancreas of female Syrian hamsters

A. Gazdar, K. Sugio, D. Kokkinakis, 2005 .

Aberrant Wnt/beta-catenin signaling in pancreatic adenocarcinoma.

A. Bell, D. Kokkinakis, A. Sood, 2006, Neoplasia.

Major urinary metabolites in hamsters and rats treated with N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine.

D. Kokkinakis, D. Scarpelli, P. Hollenberg, 1985, Cancer research.

Metabolism of /V-Nitroso-2,6-dimethylmorpholine by Isozymes of Rabbit Liver Microsomal Cytochrome P-4501

M. J. Coon, D. Kokkinakis, D. Koop, 2006 .

Metabolism of N-nitroso-2,6-dimethylmorpholine by isozymes of rabbit liver microsomal cytochrome P-450.

M. J. Coon, D. Kokkinakis, D. Koop, 1985, Cancer research.

Potential use of MDA-7 as a biological adjuvant for radiation therapy

Mansoor M Ahmed, D. Kokkinakis, M. M. Shareef, 2004, Cancer biology & therapy.

Potentiation of BCNU antitumor efficacy by 9-substituted O6-benzylguanines. Effect of metabolism

S. Schold, D. Kokkinakis, A. Pegg, 2000, Cancer Chemotherapy and Pharmacology.

Metal-mediated reduction of cytochrome c by thioglycolic acid

D. Kokkinakis, J. Everse, 1983 .

Reduction of cytochrome c by thioglycolate: Participation of catalysts

D. Kokkinakis, J. Everse, 1981 .

-deoxyguanosine and Bcnu ′ -benzyl-2 6 O Treatment of Human Brain Tumor Xenografts with Updated Version Citing Articles E-mail Alerts Treatment of Human Brain Tumor Xenografts with 06-benzyl-2'-deoxyguanosine and Bcnu1

S. Schold, D. Kokkinakis, A. Pegg, 2013 .

Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits growth of PC-3 human prostate cancer xenografts in vivo

S. Srivastava, Shivendra V. Singh, D. Kokkinakis, 2003 .

Tomato peroxidase: purification, characterization, and catalytic properties.

D. Kokkinakis, J. L. Brooks, 1979, Plant physiology.

Metabolism and activation of pancreas specific nitrosamines by pancreatic ductal cells in culture.

D. Kokkinakis, M. Reddy, K. Baskaran, 1993, Carcinogenesis.

Synergy between methionine stress and chemotherapy in the treatment of brain tumor xenografts in athymic mice.

E. Frenkel, R. Hoffman, S. Schold, 2001, Cancer research.

Induction of a step in carcinogenesis that is normally associated with mutagenesis by nonmutagenic concentrations of 5-azacytidine

N. Bouck, D. Kokkinakis, J. Ostrowsky, 1984, Molecular and cellular biology.

Hydrogen Peroxide-mediated Oxidation of Indole-3-acetic Acid by Tomato Peroxidase and Molecular Oxygen.

D. Kokkinakis, J. L. Brooks, 1979, Plant physiology.

Orotic acid enhancement of preneoplastic and neoplastic lesions induced in the pancreas and liver of hamsters by N-nitroso(2-hydroxypropyl) (2-oxopropyl)amine.

D. Kokkinakis, J. Albores–Saavedra, 1994, Cancer research.

Thresholds of O6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide.

S. Schold, D. Bocangel, D. Kokkinakis, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Eradication of human medulloblastoma tumor xenografts with a combination of O6-benzyl-2'-deoxyguanosine and 1,3-bis(2-chloroethyl)1-nitrosourea.

S. Schold, D. Kokkinakis, A. Pegg, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

O6-benzylguanine suppression of O6-alkylguanine-DNA alkyltransferase in anaplastic gliomas.

Susan M. Chang, M. Berger, M. Prados, 2004, Neuro-oncology.

Lack of evidence for a polymorphism at codon 160 of human O6-alkylguanine-DNA alkyltransferase gene in normal tissue and cancer.

M. Dolan, H. Friedman, M. Wu, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Phase I trial of O6-benzylguanine for patients undergoing surgery for malignant glioma.

M M Haglund, T Kerby, R. McLendon, 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Role of O6-methylguanine-DNA methyltransferase in the resistance of pancreatic tumors to DNA alkylating agents.

M. Mohiuddin, M. Ahmed, D. Kokkinakis, 1997, Cancer research.

Mechanism of depletion of O6-methylguanine-DNA methyltransferase activity in rat tissues by O6-Benzyl-2'-deoxyguanosine. Role of metabolism.

S. Schold, D. Kokkinakis, A. Pegg, 1996, In Vivo.

Metabolism and disposition of O6-benzyl-2'-deoxyguanosine in Sprague-Dawley rats.

M. Dolan, S. Schold, D. Kokkinakis, 1994, Chemical Research in Toxicology.

DNA alkylation in the hamster induced by two pancreatic carcinogens.

D. Kokkinakis, D. Scarpelli, 1989, Cancer research.

Modulation of Gene Expression in Human Central Nervous System Tumors under Methionine Deprivation-induced Stress

S. Chada, Mansoor M Ahmed, D. Kokkinakis, 2004, Cancer Research.

Aberrant Wnt/β-Catenin Signaling in Pancreatic Adenocarcinoma

A. Bell, D. Kokkinakis, A. Sood, 2006 .

Effect of long-term depletion of plasma methionine on the growth and survival of human brain tumor xenografts in athymic mice.

S. Schold, D. Kokkinakis, T. Nobori, 1997, Nutrition and cancer.

Metabolism of pancreatic carcinogens N-nitroso-2,6-dimethylmorpholine and N-nitrosobis(2-oxopropyl)amine by microsomes and cytosol of hamster pancreas and liver.

D. Kokkinakis, M. Rao, D. Scarpelli, 1983, Cancer research.

Total Methionine Restriction Treatment of Cancer.

E. Frenkel, R. Hoffman, D. Kokkinakis, 2019, Methods in molecular biology.

Tumorigenesis and Neoplastic Progression CSR1 Suppresses Tumor Growth and Metastasis of Prostate Cancer

G. Tseng, Guoying Yu, J. Nelson, 2006 .

Mitotic Arrest, Apoptosis, and Sensitization to Chemotherapy of Melanomas by Methionine Deprivation Stress

J. Kirkwood, S. Chada, D. Bocangel, 2006, Molecular Cancer Research.

Differences between pancreatropic nitrosamine carcinogens and N-nitrosodimethylamine in methylating DNA in various tissues of hamsters and rats.

D. Kokkinakis, 1991, Chemico-biological interactions.

Characterization of initiated cells in N-methylnitrosourea-induced carcinogenesis of the CNS in the adult rat.

L. Honig, S. Schold, D. Kokkinakis, 2001, Neuro-oncology.

Sex differences in the dietary modulation of pancreatic cancer in Syrian hamsters treated continuously with N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine.

D. Kokkinakis, 1990, Carcinogenesis.

Methionine-stress: a pleiotropic approach in enhancing the efficacy of chemotherapy.

D. Kokkinakis, 2006, Cancer letters.

Metabolism of the cis and trans isomers of N-nitroso-2,6-dimethylmorpholine and their deuterated analogs by liver microsomes of rat and hamster.

D. Kokkinakis, D. Scarpelli, P. Hollenberg, 1984, Carcinogenesis.

Differences in DNA-guanine alkylation between male Sprague-Dawley rats and Syrian hamsters following exposure to a single dose of pancreatic nitrosamine carcinogens.

D. Kokkinakis, 1990, Chemical research in toxicology.

Species differences in the metabolism of N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine.

D. Kokkinakis, V. Subbarao, D. Scarpelli, 1987, Carcinogenesis.

Structural relationships of pancreatic nitrosamine carcinogens.

D. Kokkinakis, D. Scarpelli, P. Hollenberg, 1987, Carcinogenesis.

Metabolism of the pancreatic carcinogen N-nitroso-2,6-dimethylmorpholine by hamster liver and component cells of pancreas.

D. Kokkinakis, M. Rao, V. Subbarao, 1982, Cancer research.

Component Cells of Pancreas-Nitroso-2 , 6-dimethylmorpholine by Hamster Liver and N Metabolism of the Pancreatic Carcinogen Updated

Rao, D. Kokkinakis, V. Subbarao, 2006 .

Alkylation of rodent tissue DNA induced by N-nitrosobis(2-hydroxypropyl)amine.

D. Kokkinakis, 1992, Carcinogenesis.

The significance of DNA damage, its repair and cell proliferation during carcinogen treatment in the initiation of pancreatic cancer in the hamster model.

D. Kokkinakis, V. Subbarao, 1993, Cancer research.

Metabolic response of normal and malignant tissue to acute and chronic methionine stress in athymic mice bearing human glial tumor xenografts.

D. Kokkinakis, Qing Zhou, J. B. Wick, 2002, Chemical Research in Toxicology.

Enhancement of N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine-induced tumorigenesis in Sprague-Dawley rats by orotic acid.

D. Kokkinakis, D. Scarpelli, R. Oyasu, 1991, Carcinogenesis.

Treatment of human brain tumor xenografts with O6-benzyl-2'-deoxyguanosine and BCNU.

S. Schold, D. Kokkinakis, A. Pegg, 1996, Cancer research.

High yields of K-ras mutations in intraductal papillary mucinous tumors and invasive adenocarcinomas induced by N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine in the pancreas of female Syrian hamsters.

A. Gazdar, K. Sugio, D. Kokkinakis, 1996, Carcinogenesis.

Carcinogenicity of N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine, N-nitrosobis(2-hydroxypropyl)amine and cis-N-nitroso-2,6-dimethylmorpholine administered continuously in the Syrian hamster, and the effect of dietary protein on N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine carcinogenesis.

D. Kokkinakis, D. Scarpelli, 1989, Carcinogenesis.