J. Loeffler

发表

Repression of the basal c-fos promoter by wild-type p53.

B. Seizinger, N. Kley, R. Chung, 1992, Nucleic acids research.

Electrophysiological study with K+- and Ca2+-sensitive micropipettes of GABA receptors in the rat neurointermediate lobe in vitro

J. Loeffler, B. Demeneix, P. Feltz, 1982, Neuroscience Letters.

Immune cell-derived beta-endorphin. Production, release, and control of inflammatory pain in rats.

J. Loeffler, J. Loeffler, P. Cabot, 1997, The Journal of clinical investigation.

Thyrotropin-releasing hormone stimulates porcine melanotrope cells in primary culture

J. Loeffler, B. Demeneix, J. Trouslard, 1989, Neuroscience Letters.

The tissue-specific transcription factor Pit-1/GHF-1 binds to the c-fos serum response element and activates c-fos transcription.

J. Loeffler, C. Gaiddon, M. Tapia, 1999, Molecular endocrinology.

Proenkephalin B Messenger RNA in Porcine Tissues: Characterization, Quantification, and Correlation with Opioid Peptides

N. Kley, J. Loeffler, J. Loeffler, 1987, Journal of neurochemistry.

Pituitary adenylate cyclase-activating polypeptide stimulates proenkephalin gene transcription through AP1- and CREB-dependent mechanisms.

J. Loeffler, D. Monnier, 1998, DNA and cell biology.

Characterization of a corticotropin-releasing hormone-responsive element in the rat proopiomelanocortin gene promoter and molecular cloning of its binding protein.

J. Roberts, J. Loeffler, M. Glucksman, 1994, Molecular endocrinology.

Ruthenium (II)-Derived Organometallic Compounds Induce Cytostatic and Cytotoxic Effects on Mammalian Cancer Cell Lines through p53-Dependent and p53-Independent Mechanisms

C. Sirlin, J. Loeffler, P. Bischoff, 2005, Journal of Pharmacology and Experimental Therapeutics.

Constitutively active G(S) alpha-subunits stimulate Pit-1 promoter activity via a protein kinase A-mediated pathway acting through deoxyribonucleic acid binding sites both for Pit-1 and for adenosine 3',5'-monophosphate response element-binding protein.

J. Loeffler, C. Gaiddon, C. Bancroft, 1996, Endocrinology.

Transcriptional effects in GH3 cells of Gs alpha mutants associated with human pituitary tumors: stimulation of adenosine 3',5'-monophosphate response element-binding protein-mediated transcription and of prolactin and growth hormone promoter activity via protein kinase A.

J. Loeffler, C. Gaiddon, L. Mercken, 1995, Endocrinology.

αMSH stimulates cAMP-dependent gene transcription in cerebellar neurons

J. Loeffler, F. Barthel, J. Félix, 1994, Regulatory Peptides.

Oncogenic Gαs proteins stimulate proopiiomelanocortin (POMC) and proenkephalin (PEnk) gene transcription

J. Loeffler, C. Gaiddon, D. Monnier, 1994, Regulatory Peptides.

PACAP 27 and 38 stimulate proopiomelanocortin (POMC) and proenkephalin (PENK) gene transcription

J. Loeffler, F. Barthel, C. Gaiddon, 1994, Regulatory Peptides.

Molecular Mechanisms in Proenkephalin Gene Regulation

N. Kley, J. Loeffler, 1993 .

γ-aminobutyric acid decreases levels of messenger ribonucleic acid encoding prolactin in the rat pituitary

N. Kley, J. Loeffler, V. Höllt, 1985, Neuroscience Letters.

Sprouty2 inhibits BDNF-induced signaling and modulates neuronal differentiation and survival

J. Licht, J. Loeffler, O. Armant, 2007, Cell Death and Differentiation.

Melanocortin receptors and δ‐opioid receptor mediate opposite signalling actions of POMC‐derived peptides in CATH.a cells

B. Kieffer, J. Loeffler, J. Loeffler, 1998, The European journal of neuroscience.

Ca2+/calmodulin kinase types II and IV regulate c-fos transcription in the AtT20 corticotroph cell line

J. Loeffler, C. Gaiddon, M. Antoine, 1996, Molecular and Cellular Endocrinology.

Beta-adrenergic stimulation of cFOS via protein kinase A is mediated by cAMP regulatory element binding protein (CREB)-dependent and tissue-specific CREB-independent mechanisms in corticotrope cells.

J. Roberts, J. Loeffler, F. Barthel, 1992, The Journal of biological chemistry.

Calcium ion and cyclic adenosine 3',5'-monophosphate regulate proopiomelanocortin messenger ribonucleic acid levels in rat intermediate and anterior pituitary lobes.

N. Kley, J. Loeffler, V. Höllt, 1986, Endocrinology.

Pituitary adenyl cyclase-activating peptide: a hypophysiotropic factor that stimulates proopiomelanocortin gene transcription, and proopiomelanocortin-derived peptide secretion in corticotropic cells.

J. Loeffler, D. Monnier, A. Boutillier, 1994, Neuroendocrinology.

Proenkephalin A gene expression in bovine adrenal chromaffin cells is regulated by changes in electrical activity.

N. Kley, J. Loeffler, V. Höllt, 1986, The EMBO journal.

Differential upregulation of extracellular matrix molecules associated with the appearance of granule cell dispersion and mossy fiber sprouting during epileptogenesis in a murine model of temporal lobe epilepsy

Y. Larmet, J. Loeffler, A. Faissner, 2004, Neuroscience.

GABAA and GABAB receptors on porcine pars intermedia cells in primary culture: Functional role in modulating peptide release

J. Loeffler, B. Demeneix, O. Taleb, 1986, Neuroscience.

GABA differentially regulates the gene expression of proopiomelanocortin in rat intermediate and anterior pituitary

N. Kley, J. Loeffler, B. Demeneix, 1986, Peptides.

Pre- and postsynaptic actions of GABA on the release of hypothalamic gonadotropin-releasing hormone (GnRH)

J. Loeffler, A. Herz, O. Almeida, 1988, Brain Research Bulletin.

Insulin-like growth factor-I stimulates c-fos and c-jun transcription in PC12 cells

J. Zwiller, D. Aunis, J. Loeffler, 1994, Molecular and Cellular Endocrinology.

Lipopolyamine‐Mediated Transfection Allows Gene Expression Studies in Primary Neuronal Cells

P. Sassone-Corsi, J. Loeffler, J. Behr, 1990, Journal of neurochemistry.

Corticotropin-releasing hormone stimulates proopiomelanocortin transcription by cFos-dependent and -independent pathways: characterization of an AP1 site in exon 1.

J. Roberts, J. Loeffler, D. Lorang, 1995, Molecular endocrinology.

Ca2+ Regulates Hormone Secretion and Proopiomelanocortin Gene Expression in Melanotrope Cells via the Calmodulin and the Protein Kinase C Pathways

N. Kley, J. Loeffler, B. Demeneix, 1989, Journal of Neurochemistry.

Genomic effects of the putative oncogene G alpha s. Chronic transcriptional activation of the c-fos proto-oncogene in endocrine cells.

J. Loeffler, C. Gaiddon, L. Mercken, 1994, The Journal of biological chemistry.

Corticotropin-releasing factor and forskolin increase proopiomelanocortin messenger RNA levels in rat anterior and intermediate cells in vitro

N. Kley, J. Loeffler, V. Höllt, 1985, Neuroscience Letters.

Histone deacetylase inhibitors: therapeutic agents and research tools for deciphering motor neuron diseases.

J. Loeffler, A. Echaniz-Laguna, O. Bousiges, 2008, Current medicinal chemistry.

The protooncogene c-fos is induced by corticotropin-releasing factor and stimulates proopiomelanocortin gene transcription in pituitary cells.

P. Sassone-Corsi, J. Loeffler, A. Boutillier, 1991, Molecular endocrinology.

Multiple neurotoxic stresses converge on MDMX proteolysis to cause neuronal apoptosis

A. Jochemsen, J. Loeffler, I. Gross, 2007, Cell Death and Differentiation.

C2‐ceramide and reactive oxygen species inhibit pituitary adenylate cyclase activating polypeptide (PACAP)‐induced cyclic‐AMP‐dependent signalling pathway

V. Sée, J. Loeffler, B. Koch, 2001, Journal of neurochemistry.

In vivo and in vitro studies of GABAergic inhibition of prolactin biosynthesis.

N. Kley, J. Loeffler, O. Almeida, 1986, Neuroendocrinology.

Pharmacological, molecular and functional characterization of vasoactive intestinal polypeptide/pituitary adenylate cyclase-activating polypeptide receptors in the rat pineal gland

H. Vaudry, J. Loeffler, P. Pévet, 1998, Neuroscience.

Regulation of proopiomelanocortin (POMC) mRNA levels in primary pituitary cultures.

N. Kley, J. Loeffler, V. Höllt, 1986, NIDA research monograph.

Involvement of ion channels in the induction of proenkephalin A gene expression by nicotine and cAMP in bovine chromaffin cells.

N. Kley, J. Loeffler, V. Höllt, 1987, The Journal of biological chemistry.

Brain‐Derived Neurotrophic Factor Stimulates AP‐1 and Cyclic AMP‐Responsive Element Dependent Transcriptional Activity in Central Nervous System Neurons

Y. Larmet, J. Loeffler, C. Gaiddon, 1996, Journal of neurochemistry.

Striatal proenkephalin turnover and gene transcription are regulated by cyclic AMP and protein kinase c-related pathways

J. Loeffler, F. Barthel, M. Grino, 1991, Neuroscience.

Ionic Movements Related to GABA Action on Neurosecretory Fibers and Endocrine Cells of the Hypophyseal Neurointermediate Lobe

J. Loeffler, B. Demeneix, P. Feltz, 1985 .

Ca2+-dependent histaminergic regulation of proenkephalin mRNA levels in cultured adrenal chromaffin cells.

N. Kley, J. Loeffler, V. Höllt, 1987, Neuroendocrinology.

Differentiation to a neuronal phenotype in bovine chromaffin cells is repressed by protein kinase C and is not dependent on c-fos oncoproteins.

N. Kley, J. Loeffler, B. Demeneix, 1990, DNA and cell biology.

PACAP type I receptor activation promotes cerebellar neuron survival through the cAMP/PKA signaling pathway.

J. Loeffler, C. Crochemore, F. René, 1997, DNA and cell biology.

Ionic conductances related to GABA action on secretory and biosynthetic activity of pars intermedia cells

N. Kley, J. Loeffler, B. Demeneix, 1986, Brain Research Bulletin.

Properties of the GABA receptors located on spinal primary afferent neurones and hypophyseal neuroen-docrine cells of the rat

J. Loeffler, B. Demeneix, P. Feltz, 1984, Neuroscience Letters.

Comparative study of GABA-mediated depolarizations of lumbar Aδ and C primary afferent neurones of the rat

J. Loeffler, P. Feltz, F. Santangelo, 2004, Experimental Brain Research.

Influence of calcium ions on proopiomelanocortin mRNA levels in clonal anterior pituitary cells.

J. Loeffler, V. Höllt, C. Grimm, 1988, Neuroendocrinology.

Quantitation of proenkephalin A messenger RNA in bovine brain, pituitary and adrenal medulla: correlation between mRNA and peptide levels.

N. Kley, J. Loeffler, V. Höllt, 1985, The EMBO journal.

Assignment of the beta-thyroid hormone receptor to 3,5,3'-triiodothyronine-dependent inhibition of transcription from the thyrotropin-releasing hormone promoter in chick hypothalamic neurons.

J. Loeffler, B. Demeneix, F. Lezoualc'h, 1992, Molecular endocrinology.

Corticotropin-releasing hormone stimulates proopiomelanocortin transcription by cFos-dependent and -independent pathways: characterization of an AP1 site in exon 1.

J. Loeffler, D. Lorang, J. Lundblad, 1995, Molecular endocrinology.

Fine tuning of calcium entry into neurons regulates adenosine 3′,5′-monophosphate-dependent transcription by several distinct mechanisms

J. Loeffler, F. Barthel, J. Trouslard, 1996, Neuroscience.

GABAB receptors negatively regulate transcription in cerebellar granular neurons through cyclic AMP responsive element binding protein-dependent mechanisms

J. Loeffler, B. Demeneix, F. Barthel, 1996, Neuroscience.

Pituitary adenylate cyclase-activating polypeptide transduces through cAMP/PKA and PKC pathways and stimulates proopiomelanocortin gene transcription in mouse melanotropes.

J. Loeffler, C. Gaiddon, J. Félix, 1996, Neuroendocrinology.

β2‐Adrenoreceptors Stimulate c‐fos Transcription Through Multiple Cyclic AMP‐ and Ca2+‐Responsive Elements in Cerebellar Granular Neurons

J. Loeffler, F. Barthel, 1995, Journal of neurochemistry.

Characterization and Genetic Analysis of Functional Corticotropin‐Releasing Hormone Receptors in Primary Cerebellar Cultures

J. Loeffler, F. Barthel, 1993, Journal of neurochemistry.