Lidia Gaffke

发表

Complex Changes in the Efficiency of the Expression of Many Genes in Monogenic Diseases, Mucopolysaccharidoses, May Arise from Significant Disturbances in the Levels of Factors Involved in the Gene Expression Regulation Processes

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2022, Genes.

Correction of Huntington’s Disease Phenotype by Genistein-Induced Autophagy in the Cellular Model

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2018, NeuroMolecular Medicine.

Mucopolysaccharidosis and Autophagy: Controversies on the Contribution of the Process to the Pathogenesis and Possible Therapeutic Applications

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2019, NeuroMolecular Medicine.

Transcriptomic analyses suggest that mucopolysaccharidosis patients may be less susceptible to COVID‐19

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2020, FEBS letters.

Gene Expression-Related Changes in Morphologies of Organelles and Cellular Component Organization in Mucopolysaccharidoses

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2021, International journal of molecular sciences.

Underestimated Aspect of Mucopolysaccharidosis Pathogenesis: Global Changes in Cellular Processes Revealed by Transcriptomic Studies

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2020, International Journal of Molecular Sciences.

Untypically mild phenotype of a patient suffering from Sanfilippo syndrome B with the c.638C>T/c.889C>T (p.Pro213Leu/p.Arg297Ter) mutations in the NAGLU gene

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2020, Molecular genetics & genomic medicine.

Hair dysmorphology in the R6/1 and R6/2 mouse models of Huntington's disease.

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2020, Gene.

Genistein induces degradation of mutant huntingtin in fibroblasts from Huntington’s disease patients

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2019, Metabolic Brain Disease.

Ferroptosis and Its Modulation by Autophagy in Light of the Pathogenesis of Lysosomal Storage Diseases

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2021, Cells.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Biological aspects of phage therapy versus antibiotics against Salmonella enterica serovar Typhimurium infection of chickens

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2022, Frontiers in Cellular and Infection Microbiology.

Behavioral- and blood-based biomarkers for Huntington's disease: Studies on the R6/1 mouse model with prospects for early diagnosis and monitoring of the disease

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2022, Brain, behavior, & immunity - health.

Oxidative Stress in Mucopolysaccharidoses: Pharmacological Implications

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2021, Molecules.

How close are we to therapies for Sanfilippo disease?

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2017, Metabolic Brain Disease.

Genetic Base of Behavioral Disorders in Mucopolysaccharidoses: Transcriptomic Studies

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2020, International journal of molecular sciences.

Enrofloxacin—The Ruthless Killer of Eukaryotic Cells or the Last Hope in the Fight against Bacterial Infections?

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2022, International journal of molecular sciences.

Activities of (Poly)phenolic Antioxidants and Other Natural Autophagy Modulators in the Treatment of Sanfilippo Disease: Remarkable Efficacy of Resveratrol in Cellular and Animal Models

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2022, Neurotherapeutics.

Changes in expression of signal transduction-related genes, and formation of aggregates of GPER1 and OXTR receptors in mucopolysaccharidosis cells.

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2022, European journal of cell biology.

Impaired ion homeostasis as a possible associate factor in mucopolysaccharidosis pathogenesis: transcriptomic, cellular and animal studies

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2021, Metabolic Brain Disease.

Unexplored potential: Biologically active compounds produced by microorganisms from hard-to-reach environments and their applications.

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2021, Acta biochimica Polonica.

Changes in cellular processes occurring in mucopolysaccharidoses as underestimated pathomechanisms of these diseases

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2019, Cell biology international.

Sanfilippo Syndrome: Optimizing Care with a Multidisciplinary Approach

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2022, Journal of multidisciplinary healthcare.

Expression of Long Noncoding RNAs in Fibroblasts from Mucopolysaccharidosis Patients

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2023, Genes.

Cell cycle disturbances in mucopolysaccharidoses: Transcriptomic and experimental studies on cellular models

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2022, Experimental biology and medicine.

Misdiagnosis in mucopolysaccharidoses

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2022, Journal of Applied Genetics.

Differences in gene expression patterns, revealed by RNA-seq analysis, between various Sanfilippo and Morquio disease subtypes.

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2021, Gene.

Proteasome Composition and Activity Changes in Cultured Fibroblasts Derived From Mucopolysaccharidoses Patients and Their Modulation by Genistein

E. Jankowska, Lidia Gaffke, Karolina Pierzynowska, 2020, Frontiers in Cell and Developmental Biology.

Changes in expressions of genes involved in the regulation of cellular processes in mucopolysaccharidoses as assessed by fibroblast culture-based transcriptomic analyses

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2020, Metabolic Brain Disease.

Autophagy stimulation as a promising approach in treatment of neurodegenerative diseases

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2018, Metabolic Brain Disease.

Antibacterial, Antifungal and Anticancer Activities of Compounds Produced by Newly Isolated Streptomyces Strains from the Szczelina Chochołowska Cave (Tatra Mountains, Poland)

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2021, Antibiotics.

Autophagy stimulation as a promising approach in treatment of neurodegenerative diseases

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2018, Metabolic Brain Disease.

Autophagy-dependent mechanism of genistein-mediated elimination of behavioral and biochemical defects in the rat model of sporadic Alzheimer's disease

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2019, Neuropharmacology.

Highly thermostable RadA protein from the archaeon Pyrococcus woesei enhances specificity of simplex and multiplex PCR assays

Lidia Gaffke, M. Plotka, A. Kaczorowska, 2016, Journal of Applied Genetics.

Formation of Complexes Between O Proteins and Replication Origin Regions of Shiga Toxin-Converting Bacteriophages

Lidia Gaffke, G. Węgrzyn, M. Glinkowska, 2020, Frontiers in Molecular Biosciences.

Suppression of the Escherichia coli dnaA46 mutation by changes in the activities of the pyruvate-acetate node links DNA replication regulation to central carbon metabolism

Lidia Gaffke, G. Węgrzyn, M. Glinkowska, 2017, PloS one.

Transcriptomic Changes Related to Cellular Processes with Particular Emphasis on Cell Activation in Lysosomal Storage Diseases from the Group of Mucopolysaccharidoses

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2020, International journal of molecular sciences.

Highly diverse phenotypes of mucopolysaccharidosis type IIIB sibling patients: effects of an additional mutation in the AUTS2 gene

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2022, Journal of Applied Genetics.

Elevated LysoGb3 Concentration in the Neuronopathic Forms of Mucopolysaccharidoses

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2020, Diagnostics.

The Role of Metabolites in the Link between DNA Replication and Central Carbon Metabolism in Escherichia coli

Lidia Gaffke, G. Węgrzyn, G. Muskhelishvili, 2020, Genes.

Tubulin Cytoskeleton in Neurodegenerative Diseases–not Only Primary Tubulinopathies

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2022, Cellular and Molecular Neurobiology.

Expression of genes involved in apoptosis is dysregulated in mucopolysaccharidoses as revealed by pilot transcriptomic analyses

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2020, Cell biology international.

Contribution of vesicle trafficking dysregulation to the pathomechanism of mucopolysaccharidosis.

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2023, Biochemical and biophysical research communications.

Transcriptomic Approaches in Studies on and Applications of Chimeric Antigen Receptor T Cells

J. Zaucha, Lidia Gaffke, Karolina Pierzynowska, 2023, Biomedicines.

Genistein induces degradation of mutant huntingtin in fibroblasts from Huntington’s disease patients

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2019, Metabolic brain disease.

Correction of Huntington’s Disease Phenotype by Genistein-Induced Autophagy in the Cellular Model

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2018, NeuroMolecular Medicine.

Roles of the Oxytocin Receptor (OXTR) in Human Diseases

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2023, International journal of molecular sciences.

Decreased Levels of Chaperones in Mucopolysaccharidoses and Their Elevation as a Putative Auxiliary Therapeutic Approach

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2023, Pharmaceutics.

Actin Cytoskeleton Polymerization and Focal Adhesion as Important Factors in the Pathomechanism and Potential Targets of Mucopolysaccharidosis Treatment

Lidia Gaffke, Karolina Pierzynowska, Estera Rintz, 2023, Cells.

Antimicrobial Activities of Compounds Produced by Newly Isolated Streptomyces Strains from Mountain Caves

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2022, ECA 2022.

Applications of the phage display technology in molecular biology, biotechnology and medicine.

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2023, Critical reviews in microbiology.

The use of phage display systems to combat infectious diseases in poultry: diagnostic, vaccine, and therapeutic approaches.

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2022, Journal of applied microbiology.

How close are we to therapies for Sanfilippo disease?

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2017, Metabolic brain disease.

Differential Chromosome- and Plasmid-Borne Resistance of Escherichia coli hfq Mutants to High Concentrations of Various Antibiotics

Zuzanna Cyske, Lidia Gaffke, G. Węgrzyn, 2021, International journal of molecular sciences.

Potential of genistein-induced autophagy in the treatment of neurodegenerative diseases

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2021, Postepy biochemii.

Therapeutic potential of lithium chloride and valproic acid against neuronopathic types of mucopolysaccharidoses through induction of the autophagy process

Lidia Gaffke, Karolina Pierzynowska, E. Piotrowska, 2023, Archives of Biochemistry and Biophysics.

Characterization of adenine nucleotide metabolism in the cellular model of Huntington’s disease

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2018, Nucleosides, nucleotides & nucleic acids.

Correction of symptoms of Huntington disease by genistein through FOXO3-mediated autophagy stimulation.

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2023, Autophagy.

Highly thermostable RadA protein from the archaeon Pyrococcus woesei enhances specificity of simplex and multiplex PCR assays

Lidia Gaffke, M. Plotka, A. Kaczorowska, 2015, Journal of Applied Genetics.

Bacteriophage DNA induces an interrupted immune response during phage therapy in a chicken model

Lidia Gaffke, Karolina Pierzynowska, Jagoda Mantej, 2024, Nature communications.

Enhanced Efficiency of the Basal and Induced Apoptosis Process in Mucopolysaccharidosis IVA and IVB Human Fibroblasts

Lidia Gaffke, Karolina Pierzynowska, Joanna Brokowska, 2023, International journal of molecular sciences.

Induction of the mitochondrial pathway of apoptosis by enrofloxacin in the context of the safety issue of its use in poultry.

Lidia Gaffke, Karolina Pierzynowska, Łukasz Grabowski, 2024, Apoptosis : an international journal on programmed cell death.

Molecular mechanisms of the ambroxol action in Gaucher disease and GBA1 mutation-associated Parkinson disease

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2024, Neurochemistry International.

Clinical presentation of 13 children with alkaptonuria

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2023, Journal of inherited metabolic disease.

Cellular Organelle-Related Transcriptomic Profile Abnormalities in Neuronopathic Types of Mucopolysaccharidosis: A Comparison with Other Neurodegenerative Diseases

Lidia Gaffke, Karolina Pierzynowska, Magdalena Żabińska, 2024, Current issues in molecular biology.

Cyanobacteria and their metabolites - can they be helpful in the fight against pathogenic microbes?

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2024, Blue Biotechnology.

Mucopolysaccharidosis Type IIIE: A Real Human Disease or a Diagnostic Pitfall?

Lidia Gaffke, Karolina Pierzynowska, Magdalena Żabińska, 2024, Diagnostics.

Effectiveness of Flavonoid-Rich Diet in Alleviating Symptoms of Neurodegenerative Diseases

Lidia Gaffke, Karolina Pierzynowska, Magdalena Żabińska, 2024, Foods.

Synergistic effects of resveratrol and enzyme replacement therapy in the Mucopolysaccharidosis type I.

Lidia Gaffke, Karolina Pierzynowska, Estera Rintz, 2024, Biochemical pharmacology.

Phage display and other peptide display technologies.

Lidia Gaffke, Karolina Pierzynowska, G. Węgrzyn, 2021, FEMS microbiology reviews.

Comprehensive evaluation of pathogenic protein accumulation in fibroblasts from all subtypes of Sanfilippo disease patients.

Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, 2024, Biochemical and biophysical research communications.

Dysregulation of genes coding for proteins involved in metabolic processes in mucopolysaccharidoses, evidenced by a transcriptomic approach

Lidia Gaffke, Karolina Pierzynowska, Grzegorz Węgrzyn, 2023, Metabolic Brain Disease.

Separating gene clustering in the rare mucopolysaccharidosis disease

L. Bobrowski, Zuzanna Cyske, Lidia Gaffke, 2022, Journal of Applied Genetics.