J. Kaye

发表

An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients

Timothy A. Miller, Jennifer E. Phillips-Cremins, Andrea D Matlock, 2020, bioRxiv.

Bioenergetic deficits in Huntington’s disease iPSC-derived neural cells and rescue with glycolytic metabolites

Amanda J. Kedaigle, E. Fraenkel, M. MacDonald, 2019, Human molecular genetics.

Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

Amanda J. Kedaigle, E. Fraenkel, M. MacDonald, 2017, Nature Neuroscience.

Modeling Huntington's disease with induced pluripotent stem cells

S. Finkbeiner, J. Kaye, 2013, Molecular and Cellular Neuroscience.

UC San Francisco UC San Francisco Previously Published Works Title Modeling Huntington ' s disease with induced pluripotent stem cells

S. Finkbeiner, J. Kaye, 2013 .

Title Sequence-Level Analysis of the Major European Huntington Disease Haplotype Permalink

L. Hood, J. Roach, T. Gillis, 2022 .

DNA Breaks Promote Genomic Instability by Impeding Proper Chromosome Segregation

J. Haber, D. Toczyski, J. Kaye, 2004, Current Biology.

The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein

Priya S. Shah, N. Krogan, S. Finkbeiner, 2018, mBio.

Huntington’s disease iPSC models—using human patient cells to understand the pathology caused by expanded CAG repeats

S. Finkbeiner, J. Kaye, T. Reisine, 2022, Faculty reviews.

RMeDPower for Biology: guiding design, experimental structure and analyses of repeated measures data for biological studies

S. Finkbeiner, Reuben Thomas, J. Kaye, 2022, bioRxiv.

Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines

Andrea D Matlock, J. Krakauer, K. Sachs, 2020, Nature Neuroscience.

Identifying patterns in amyotrophic lateral sclerosis progression from sparse longitudinal data

Kristen A. Severson, Andrea D Matlock, J. Krakauer, 2022, Nature Computational Science.

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene in and for Therapeutic

Timothy A. Miller, Denis C. Bauer, Shankaracharya, 2018 .

The TRPV Channel OSM-9 is Required Non-Cell Autonomously for Sleep-Dependent Olfactory Memory

J. Kaye, N. L’Etoile, Rashmi Chandra, 2022, bioRxiv.

The effect of 8-methoxypsoralen-plus ultraviolet light on cell-virus interaction: the transforming infection; effect of PUVA on the transformation of baby hamster kidney cells by polyoma virus.

J. Kaye, V. Morhenn, 1979, The Journal of investigative dermatology.

A deep learning approach to neurite prediction in high throughput fluorescence imaging

S. Finkbeiner, M. Dierssen, J. Kaye, 2021, bioRxiv.

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.

Ravi Iyengar, Vasileios Stathias, Amar Koleti, 2017, Cell systems.

Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects

E. Fraenkel, S. Finkbeiner, J. Rothstein, 2023, Neuron.

Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes.

T. Gillis, J. Mysore, M. MacDonald, 2012, Cell stem cell.

High-throughput screening in primary neurons.

Steven Finkbeiner, Aaron Daub, S. Finkbeiner, 2012, Methods in enzymology.

Nuclear accumulation of host transcripts during Zika Virus Infection

Priya S. Shah, Ryan A. Flynn, S. Finkbeiner, 2023, PLoS pathogens.

Zika Virus Infection Prevents Host mRNA Nuclear Export by Disrupting UPF1 Function

Priya S. Shah, Ryan A. Flynn, N. Krogan, 2020, bioRxiv.

A 3′UTR Pumilio-Binding Element Directs Translational Activation in Olfactory Sensory Neurons

A. Goga, J. Kaye, N. L’Etoile, 2009, Neuron.

Huntington’s disease mouse models: unraveling the pathology caused by CAG repeat expansion

S. Finkbeiner, J. Kaye, T. Reisine, 2021, Faculty reviews.

Sequence-Level Analysis of the Major European Huntington Disease Haplotype.

L. Hood, J. Roach, T. Gillis, 2015, American journal of human genetics.

Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington's disease pathology.

S. Finkbeiner, M. Sudol, G. Blandino, 2016, Human molecular genetics.

NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency

Andrea D Matlock, K. Sachs, E. Fraenkel, 2023, Scientific Data.

Identification of hepta-histidine as a candidate drug for Huntington’s disease by in silico-in vitro- in vivo-integrated screens of chemical libraries

Kazunori D. Yamada, S. Finkbeiner, H. Okano, 2016, Scientific Reports.

Contribution of the cyclic nucleotide gated channel subunit, CNG-3, to olfactory plasticity in Caenorhabditis elegans

Damien M. O’Halloran, J. Kaye, N. L’Etoile, 2017, Scientific Reports.

Enrichment of SARM1 alleles encoding variants with constitutively hyperactive NADase in patients with ALS and other motor nerve disorders

Stephen A. Goutman, A. Al-Chalabi, R. Schüle, 2021, medRxiv.

Olfactory memory consolidation requires the TRPV channel OSM-9 in sensory neurons of the circuit

Saul Kato, J. Kaye, N. L’Etoile, 2020 .

Nuclear entry of a cGMP-dependent kinase converts transient into long-lasting olfactory adaptation

Damien M. O’Halloran, Bluma J. Lesch, A. Goga, 2010, Proceedings of the National Academy of Sciences.

A foundational atlas of autism protein interactions reveals molecular convergence

Benjamin J. Polacco, T. Ideker, T. Bourgeron, 2023, bioRxiv.

MIT Open Access

Amanda J. Kedaigle, M. MacDonald, Yumay Chen, 2022 .

High-throughput screening in primary neurons.

S. Finkbeiner, J. Kaye, Punita Sharma, 2012, Methods in enzymology.