Y. Nishimura

发表

Integrated Approaches to Drug Discovery for Oxidative Stress-Related Retinal Diseases

Y. Nishimura, H. Hara, 2016, Oxidative medicine and cellular longevity.

CRISPR-mediated Bmpr2 point mutation exacerbates late pulmonary vasculopathy and reduces survival in rats with experimental pulmonary hypertension

Y. Nishimura, T. Mashimo, S. Otsuki, 2022, Respiratory Research.

Generation of a Triple-Transgenic Zebrafish Line for Assessment of Developmental Neurotoxicity during Neuronal Differentiation

Y. Nishimura, M. Ikejiri, K. Nakatani, 2019, Pharmaceuticals.

Intermediate filaments and IF-associated proteins: from cell architecture to cell proliferation

M. Inagaki, Kousuke Kasahara, Y. Nishimura, 2019, Proceedings of the Japan Academy. Series B, Physical and biological sciences.

Primary Cilia as Signaling Hubs in Health and Disease

M. Inagaki, Kousuke Kasahara, Y. Nishimura, 2018, Advanced science.

EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase

M. Inagaki, Kousuke Kasahara, T. Kiyono, 2018, Nature Communications.

New photic stimulating system with white light-emitting diodes to elicit electroretinograms from zebrafish larvae

Tetsuro Yamamoto, Y. Nishimura, M. Kondo, 2017, Documenta Ophthalmologica.

E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish

Y. Nishimura, Y. Shimada, Toshio Tanaka, 2015, Nutrition & Metabolism.

S-nitrosylation regulates mitochondrial quality control via activation of parkin

R. Takahashi, J. Zhao, Y. Nishimura, 2013, Scientific Reports.

Humoral immune response directed against LEDGF in patients with VKH.

S. Senju, Y. Nishimura, S. Ohno, 2001, Immunology letters.

Establishment of a drug evaluation model against light-induced retinal degeneration using adult pigmented zebrafish.

Y. Nishimura, H. Hara, M. Shimazawa, 2016, Journal of pharmacological sciences.

Pharmacogenomics and therapeutic target validation in cerebral vasospasm.

Y. Nishimura, M. Naka, T. Tanaka, 2000, Journal of cardiovascular pharmacology.

Editorial: Drug Repositioning: Current Advances and Future Perspectives

Y. Nishimura, H. Hara, 2018, Front. Pharmacol..

E2F4 Promotes Neuronal Regeneration and Functional Recovery after Spinal Cord Injury in Zebrafish

Y. Nishimura, Koki Kawaguchi, Toshio Tanaka, 2016, Front. Pharmacol..

Risk factors for cisplatin-induced acute kidney injury: A pilot study on the usefulness of genetic variants for predicting nephrotoxicity in clinical practice

Y. Nishimura, Kanako Saito, M. Ikejiri, 2020, Molecular and clinical oncology.

An Integrated In Silico and In Vivo Approach to Identify Protective Effects of Palonosetron in Cisplatin-Induced Nephrotoxicity

Y. Nishimura, Masatoshi Watanabe, K. Takeuchi, 2020, Pharmaceuticals.

Novel immunologic tolerance of human cancer cell xenotransplants in zebrafish.

Y. Nishimura, J. Kuroyanagi, Y. Shimada, 2016, Translational research : the journal of laboratory and clinical medicine.

EP300 Protects from Light-Induced Retinopathy in Zebrafish

Y. Nishimura, H. Hara, M. Shimazawa, 2016, Front. Pharmacol..

Overcoming Obstacles to Drug Repositioning in Japan

Y. Nishimura, H. Hara, Hideki Ito, 2017, Front. Pharmacol..

Identification of human and mouse GP-1, a putative member of a novel G-protein family.

S. Senju, Y. Nishimura, 1997, Biochemical and biophysical research communications.

Zebrafish beta-adrenergic receptor mRNA expression and control of pigmentation.

Y. Nishimura, J. Kuroyanagi, Y. Shimada, 2009, Gene.

Pharmacological profiling of zebrafish behavior using chemical and genetic classification of sleep-wake modifiers

Y. Nishimura, Koki Kawaguchi, Toshio Tanaka, 2015, Front. Pharmacol..

Chemokines protect vascular smooth muscle cells from cell death induced by cyclic mechanical stretch

Jing Zhao, Y. Nishimura, M. Yoshizumi, 2017, Scientific Reports.

Comparative Transcriptome Analysis Identifies CCDC80 as a Novel Gene Associated with Pulmonary Arterial Hypertension

Y. Nishimura, H. Sawada, Koki Kawaguchi, 2016, Front. Pharmacol..

In Vivo Imaging of the Mouse Neurovascular Unit Under Chronic Cerebral Hypoperfusion

Y. Nishimura, N. Suzuki, A. Mizoguchi, 2014, Stroke.

A High-Throughput Fluorescence-Based Assay System for Appetite-Regulating Gene and Drug Screening

Y. Nishimura, Y. Shimada, Toshio Tanaka, 2012, PloS one.

Identification of a novel indoline derivative for in vivo fluorescent imaging of blood-brain barrier disruption in animal models.

Y. Nishimura, H. Tomimoto, J. Kuroyanagi, 2013, ACS chemical neuroscience.

Brainstem Organoids From Human Pluripotent Stem Cells

Jay W. Shin, A. Muotri, T. Kishimoto, 2020, Frontiers in Neuroscience.

Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity

Y. Nishimura, Norihiro Nishimura, J. Kuroyanagi, 2010, BMC Physiology.

Repositioning of Lansoprazole as a Protective Agent Against Cisplatin-Induced Ototoxicity

Y. Nishimura, K. Takeuchi, M. Okuda, 2022, Frontiers in pharmacology.

SEMA4A mutations lead to susceptibility to light irradiation, oxidative stress, and ER stress in retinal pigment epithelial cells.

Y. Nishimura, H. Hara, M. Shimazawa, 2012, Investigative ophthalmology & visual science.

Oxidative Stress as a Common Key Event in Developmental Neurotoxicity

H. Sone, Y. Nishimura, Y. Kanda, 2021, Oxidative medicine and cellular longevity.

Potential Role for Heat Shock Protein 72 in Antagonizing Cerebral Vasospasm After Rat Subarachnoid Hemorrhage

Y. Nishimura, T. Kirino, Toshio Tanaka, 2004, Circulation.

Therapeutic Effects of Iron Chelation in Atorvastatin-Induced Intracranial Hemorrhage of Zebrafish Larvae.

Y. Nishimura, H. Hara, M. Shimazawa, 2020, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

DNA Damage Response Is Involved in the Developmental Toxicity of Mebendazole in Zebrafish Retina

Y. Nishimura, Tetsuo Kon, Koki Kawaguchi, 2016, Front. Pharmacol..

A novel, reliable method for repeated blood collection from aquarium fish.

Y. Nishimura, Norihiro Nishimura, Y. Shimada, 2013, Zebrafish.

Repeated Blood Collection for Blood Tests in Adult Zebrafish.

Y. Nishimura, Norihiro Nishimura, Y. Shimada, 2015, Journal of visualized experiments : JoVE.

Guinea pig cysteinyl leukotriene receptor 2 (gpCysLT2) mediates cell proliferation and intracellular calcium mobilization by LTC4 and LTD4.

Y. Nishimura, I. Kurokawa, H. Mizutani, 2008, BMB reports.

Perinatal Hypoxia Aggravates Occlusive Pulmonary Vasculopathy In SU5416/Hypoxia-Treated Rats Later In Life.

Y. Nishimura, I. Kobayashi, S. Otsuki, 2022, American journal of physiology. Lung cellular and molecular physiology.

Genomic organization, chromosomal localization, and alternative splicing of the human phosphodiesterase 8B gene.

Y. Nishimura, Y. Shimada, M. Hayashi, 2002, Biochemical and biophysical research communications.

Gap junction protein beta 4 plays an important role in cardiac function in humans, rodents, and zebrafish

Y. Nishimura, Y. Sawa, Y. Yoshida, 2020, PloS one.

Quantitative Phenotyping-Based In Vivo Chemical Screening in a Zebrafish Model of Leukemia Stem Cell Xenotransplantation

Y. Nishimura, J. Kuroyanagi, Y. Shimada, 2014, PloS one.

Cilia‐Mediated Insulin/Akt and ST2/JNK Signaling Pathways Regulate the Recovery of Muscle Injury

Kousuke Kasahara, Y. Nishimura, Daishi Yamakawa, 2022, Advanced science.

In vivo imaging of zebrafish retinal cells using fluorescent coumarin derivatives

Yuhei Nishimura, Norihiro Nishimura, Yasuhito Shimada, 2010, BMC Neuroscience.

Zebra fi sh β-adrenergic receptor mRNA expression and control of pigmentation

Li Zang, Y. Nishimura, Toshio Tanaka, 2009 .

Oxygen-glucose deprivation and reoxygenation on human cerebral organoids alters expression related to lipid metabolism

Y. Nishimura, K. Sugie, T. Shiota, 2020, bioRxiv.

Aurora A and AKT Kinase Signaling Associated with Primary Cilia

M. Inagaki, Y. Nishimura, Daishi Yamakawa, 2021, Cells.

Molecular cloning of novel mouse and human putative citrate lyase β-subunit

Y. Nishimura, Toshio Tanaka, J. Morikawa, 2001 .

Transcriptome analysis of anti-fatty liver action by Campari tomato using a zebrafish diet-induced obesity model

Y. Nishimura, Norihiro Nishimura, J. Kuroyanagi, 2011, Nutrition & metabolism.

Analysis of Gene-Environment Interactions Related to Developmental Disorders

Y. Nishimura, K. Kurosawa, 2022, Frontiers in Pharmacology.

Zinc finger MYND‐type containing 8 promotes tumour angiogenesis via induction of vascular endothelial growth factor‐A expression

Y. Nishimura, J. Kuroyanagi, Y. Shimada, 2014, FEBS letters.

Using zebrafish in systems toxicology for developmental toxicity testing

Y. Nishimura, T. Maruyama, Koki Kawaguchi, 2016, Congenital anomalies.

Zebrafish as a systems toxicology model for developmental neurotoxicity testing

Y. Nishimura, Y. Shimada, Toshio Tanaka, 2015, Congenital anomalies.

Primary cilia and lipid raft dynamics

M. Inagaki, Y. Nishimura, Daishi Yamakawa, 2021, Open Biology.

Novel reciprocal regulation of cAMP signaling and apoptosis by orphan G-protein-coupled receptor GPRC5A gene expression.

Y. Nishimura, Y. Shimada, Toshio Tanaka, 2006, Biochemical and biophysical research communications.

Tetraploidy in cancer and its possible link to aging

M. Inagaki, H. Goto, Kousuke Kasahara, 2018, Cancer science.

Targeting E3 Ubiquitin Ligases and Deubiquitinases in Ciliopathy and Cancer

Y. Bessho, M. Inagaki, Kousuke Kasahara, 2020, International journal of molecular sciences.

Zebrafish-based systems pharmacology of cancer metastasis.

Y. Nishimura, Y. Shimada, Toshio Tanaka, 2014, Methods in molecular biology.

Mouse and human GTPBP2, newly identified members of the GP-1 family of GTPase.

S. Senju, Y. Nishimura, H. Kudo, 2000, Biochemical and biophysical research communications.

Calcium-dependent Activation of Nuclear Factor Regulated by Interleukin 3/Adenovirus E4 Promoter-binding Protein Gene Expression by Calcineurin/Nuclear Factor of Activated T Cells and Calcium/Calmodulin-dependent Protein Kinase Signaling*

Y. Nishimura, Toshio Tanaka, 2001, The Journal of Biological Chemistry.

Downregulation of GSTK1 Is a Common Mechanism Underlying Hypertrophic Cardiomyopathy

Y. Nishimura, Masaaki Ito, Koki Kawaguchi, 2016, Front. Pharmacol..

Identification of a novel autoantigen UACA in patients with panuveitis.

S. Senju, Y. Nishimura, Y. Nishimura, 2001, Biochemical and biophysical research communications.

Fluorescent-Based Methods for Gene Knockdown and Functional Cardiac Imaging in Zebrafish

Y. Nishimura, Norihiro Nishimura, J. Kuroyanagi, 2013, Molecular Biotechnology.

Increased susceptibility to oxidative stress-induced toxicological evaluation by genetically modified nrf2a-deficient zebrafish.

Y. Nishimura, I. Miyawaki, Akihito Yamashita, 2019, Journal of pharmacological and toxicological methods.

[Pharmacogenomics and pharmainformatics].

Y. Nishimura, M. Naka, Toshio Tanaka, 2002, Nihon rinsho. Japanese journal of clinical medicine.

In Vivo Detection of Mitochondrial Dysfunction Induced by Clinical Drugs and Disease-Associated Genes Using a Novel Dye ZMJ214 in Zebrafish.

Y. Nishimura, Koki Kawaguchi, J. Koiwa, 2016, ACS chemical biology.

Eriocitrin ameliorates diet-induced hepatic steatosis with activation of mitochondrial biogenesis

Y. Nishimura, Norihiro Nishimura, J. Kuroyanagi, 2014, Scientific Reports.

Downregulation of stanniocalcin 1 is responsible for sorafenib-induced cardiotoxicity.

Y. Nishimura, J. Kuroyanagi, Y. Shimada, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

Oxidative Stress in Retinal Diseases

Y. Nishimura, H. Hara, M. Kondo, 2017, Oxidative medicine and cellular longevity.

Potential protective function of the sterol regulatory element binding factor 1–fatty acid desaturase 1/2 axis in early-stage age-related macular degeneration

Y. Nishimura, Koki Kawaguchi, Y. Shimada, 2017, Heliyon.

In vivo assessment of the permeability of the blood-brain barrier and blood-retinal barrier to fluorescent indoline derivatives in zebrafish

Y. Nishimura, J. Kuroyanagi, Y. Shimada, 2012, BMC Neuroscience.

Primary cilia-dependent lipid raft/caveolin dynamics regulate adipogenesis.

M. Inagaki, Kousuke Kasahara, Y. Nishimura, 2021, Cell reports.

Activation of Sterol Regulatory Element Binding Factors by Fenofibrate and Gemfibrozil Stimulates Myelination in Zebrafish

Y. Nishimura, Koki Kawaguchi, Toshio Tanaka, 2016, Front. Pharmacol..

Systems pharmacology of adiposity reveals inhibition of EP300 as a common therapeutic mechanism of caloric restriction and resveratrol for obesity

Y. Nishimura, R. Takata, Koki Kawaguchi, 2015, Front. Pharmacol..

EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase

M. Inagaki, Kousuke Kasahara, T. Kiyono, 2018, Nature Communications.

C3orf70 Is Involved in Neural and Neurobehavioral Development

Y. Bessho, Y. Nishimura, Takashi Shiromizu, 2019, Pharmaceuticals.

Chemokines protect vascular smooth muscle cells from cell death induced by cyclic mechanical stretch

Y. Nishimura, M. Yoshizumi, T. Kondo, 2017, Scientific Reports.

Generation of a Transgenic Zebrafish Line for In Vivo Assessment of Hepatic Apoptosis

H. Goto, Y. Nishimura, Takashi Shiromizu, 2021, Pharmaceuticals.

Editorial: Model organisms in predictive toxicology 2022

T. Kudoh, Y. Nishimura, Munekazu Komada, 2023, Frontiers in Pharmacology.

Brainstem organoids from human pluripotent stem cells contain neural crest population

Jay W. Shin, A. Muotri, T. Kishimoto, 2019, bioRxiv.

Green tea extract suppresses adiposity and affects the expression of lipid metabolism genes in diet-induced obese zebrafish

Y. Takema, Y. Nishimura, J. Kuroyanagi, 2012, Nutrition & Metabolism.

Downregulation of Max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice

Y. Nishimura, J. Kuroyanagi, Y. Shimada, 2014, International Journal of Obesity.

Involvement of homeobox transcription factor Mohawk in palatogenesis

Y. Nishimura, Takashi Shiromizu, J. Koiwa, 2021, Congenital anomalies.

Zebrafish xenotransplantation model for cancer stem-like cell study and high-throughput screening of inhibitors

Y. Nishimura, J. Kuroyanagi, Y. Shimada, 2014, Tumor Biology.

In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5(3).

Y. Nishimura, J. Kuroyanagi, Y. Shimada, 2015, Biomaterials.

Pharmacogenomics of cardiovascular pharmacology: pharmacogenomic network of cardiovascular disease models.

Y. Nishimura, J. Kuroyanagi, Y. Shimada, 2008, Journal of pharmacological sciences.

Increased CYFIP1 dosage alters cellular and dendritic morphology and dysregulates mTOR

D. Geschwind, B. Abrahams, G. Coppola, 2014, Molecular Psychiatry.

Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins.

Y. Nishimura, M. Hayashi, H. Inada, 1999, Biochemical and biophysical research communications.

Gene Expression Profiles of Human Cerebral Organoids Identify PPAR Pathway and PKM2 as Key Markers for Oxygen-Glucose Deprivation and Reoxygenation

Mari Nakanishi, Y. Nishimura, Tatsuhide Tanaka, 2021, Frontiers in Cellular Neuroscience.

In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5(3).

Y. Nishimura, Toshio Tanaka, M. Ariyoshi, 2015, Biomaterials.

In Vivo Imaging of the Mouse Neurovascular Unit Under Chronic Cerebral Hypoperfusion

Y. Nishimura, N. Suzuki, A. Mizoguchi, 2014, Stroke.