G. Vance

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Novel phenotype of 5p13.3-q11.2 duplication resulting from supernumerary marker chromosome 5: implications for management and genetic counseling

B. Landis, S. Ware, M. E. Armstrong, 2018, Molecular Cytogenetics.

Clinical laboratory reports in molecular pathology.

M. Gulley, R. Braziel, S. Ogino, 2007, Archives of pathology & laboratory medicine.

Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.

N. Socci, A. Viale, A. Ferrando, 2012, The New England journal of medicine.

Improvements in cytogenetic slide preparation: controlled chromosome spreading, chemical aging and gradual denaturing.

P. Bray-Ward, D. Ward, N. Heerema, 2001, Cytometry.

Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update.

John M S Bartlett, Patrick Fitzgibbons, Mitch Dowsett, 2014, Archives of pathology & laboratory medicine.

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer.

Anthony Rhodes, Lisa M McShane, Soonmyung Paik, 2006, Archives of pathology & laboratory medicine.

Characterization of neo-centromeres in marker chromosomes lacking detectable alpha-satellite DNA.

S. Schwartz, H. Willard, W. Earnshaw, 1997, Human molecular genetics.

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer.

Anthony Rhodes, Lisa M McShane, Soonmyung Paik, 2007, Archives of pathology & laboratory medicine.

Referral Patterns of Indiana Oncologists for Colorectal Cancer Genetic Services

L. Wetherill, G. Vance, Jessica Claybrook, 2010, Journal of Cancer Education.

Complementation of hypersensitivity to DNA interstrand crosslinking agents demonstrates that XRCC2 is a Fanconi anaemia gene

A. Jankowska, F. Alkuraya, P. Andreassen, 2016, Journal of Medical Genetics.

Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.

G. Vance, G. Nalepa, H. Hanenberg, 2010, Blood.

Chronic lymphocytic leukemia/small lymphocytic lymphoma with trisomy 12 and focal cyclin d1 expression: a potential diagnostic pitfall.

G. Vance, D. O’Malley, A. Orazi, 2009, Archives of pathology & laboratory medicine.

Detection of monosomy 7 in bone marrow by fluorescence in situ hybridization. A study of Fanconi anemia patients and review of the literature.

N. Heerema, G. Vance, V. Thurston, 1999, Cancer genetics and cytogenetics.

Variable phenotype of familial adenomatous polyposis in pedigrees with 3′ mutation in the APC gene

S. Powell, D. Ahnen, G. Petersen, 1998, Gut.

THE BOTTOM LINE Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer : American Society of Clinical Oncology / College of American Pathologists Clinical Practice Guideline Focused Update Guideline Questions

I. Ellis, M. Dowsett, M. Hammond, 2018 .

Utility of Fluorescence In Situ Hybridization in Clinical and Research Applications.

Wahab A. Khan, G. Vance, 2020, Clinics in laboratory medicine.

Large cell carcinoma of the lung mimicking a germ cell tumor: the potential value of chromosome analysis.

N. Hanna, T. Ulbright, G. Vance, 2005, Lung cancer.

Establishment and characterization of a novel cell line derived from human thymoma AB tumor

Lang Li, G. Sledge, R. Nelson, 2012, Laboratory Investigation.

Erratum: Problems with ISCN FISH Nomenclature make it not practical for use in clinical test reports or cytogenetics databases (Genetics in Medicine (2003) 5 (370-377))

G. Vance, A. Brothman, G. Dewald, 2003 .

Problems with ISCN FISH Nomenclature make it not practical for use in clinical test reports or cytogenetic databases [corrected].

G. Vance, A. Brothman, G. Dewald, 2003, Genetics in medicine : official journal of the American College of Medical Genetics.

As currently formulated, ISCN FISH nomenclature make it not practical for use in clinical test reports or cytogenetic databases

G. Vance, A. Brothman, G. Dewald, 2003, Genetics in Medicine.

Validation of Scales to Measure Benefits of and Barriers to Colorectal Cancer Screening

U. Menon, C. Skinner, V. Champion, 2001 .

Preanalytics and Precision Pathology: Pathology Practices to Ensure Molecular Integrity of Cancer Patient Biospecimens for Precision Medicine.

Matthew W. Anderson, C. Compton, K. Bloom, 2019, Archives of pathology & laboratory medicine.

Interphase FISH demonstrates that human adipose stromal cells maintain a high level of genomic stability in long-term culture.

A. Breman, G. Vance, K. March, 2009, Stem cells and development.

G. Vance, M. Nassiri, Sujata Chakraborty, 2014, Cancer genetics.

AML1-FOG2 fusion protein in myelodysplasia.

M. Slovak, R. Hromas, C. Willman, 2004, Blood.

Pretransplant HLA typing revealed loss of heterozygosity in the major histocompatibility complex in a patient with acute myeloid leukemia.

A. Breman, G. Vance, A. Lobashevsky, 2019, Human immunology.

Molecular cytogenetic analysis of patients with holoprosencephaly and structural rearrangements of 7q.

G. Vance, M. Butler, O. Henegariu, 1998, American journal of medical genetics.

Molecular genetic tests for FLT3, NPM1, and CEBPA in acute myeloid leukemia.

G. Vance, S. Bai, Qing Zhang, 2013, Methods in molecular biology.

Testing for BRCA1 in hereditary breast cancer.

G. Vance, 1995, JAMA.

Dicentric (9;20)(p11;q11) identified by fluorescence in situ hybridization in four pediatric acute lymphoblastic leukemia patients.

N. Heerema, G. Vance, P. Breitfeld, 1996, Cancer genetics and cytogenetics.

Positive cell-free fetal DNA testing for trisomy 13 reveals confined placental mosaicism

D. Weaver, G. Vance, M. P. Abernathy, 2013, Genetics in Medicine.

An apparently acentric marker chromosome originating from 9p with a functional centromere without detectable alpha and beta satellite sequences.

S. Schwartz, N. Heerema, G. Vance, 1997, American journal of medical genetics.

Distal 13q Deletion Syndrome and the VACTERL association: case report, literature review, and possible implications.

D. Weaver, G. Vance, L. Walsh, 2001, American journal of medical genetics.

Secondary leukemias in refractory germ cell tumor patients undergoing autologous stem-cell transplantation using high-dose etoposide.

L. Einhorn, G. Vance, R. Abonour, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Update on late relapse of germ cell tumor: a clinical and molecular analysis.

Sin-Ho Jung, N. Heerema, T. Ulbright, 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Proficiency testing for laboratories performing fluorescence in situ hybridization with chromosome-specific DNA probes.

G. Vance, A. Brothman, G. Dewald, 2002, Archives of pathology & laboratory medicine.

Detection of clonal IGH gene rearrangements: summary of molecular oncology surveys of the College of American Pathologists.

M. Gulley, R. Braziel, M. Nikiforova, 2007, Archives of pathology & laboratory medicine.

Utility of interphase FISH to stratify patients into cytogenetic risk categories at diagnosis of AML in an Eastern Cooperative Oncology Group (ECOG) clinical trial (E1900).

A. Cherry, M. Tallman, G. Vance, 2007, Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis.

Cytogenetic and molecular analysis of a ring (21) in a patient with partial trisomy 21 and megakaryocytic leukemia.

J. Korenberg, N. Heerema, M. Bull, 1994, American journal of medical genetics.

Acute panmyelosis with myelofibrosis: an entity distinct from acute megakaryoblastic leukemia

P. Banks, M. Czader, G. Vance, 2005, Modern Pathology.

Expanding the genotype–phenotype correlation in subtelomeric 19p13.3 microdeletions using high resolution clinical chromosomal microarray analysis

P. Stankiewicz, Ankita Patel, S. Cheung, 2013, American journal of medical genetics. Part A.

A multicenter investigation with interphase fluorescence in situ hybridization using X- and Y-chromosome probes.

S. Schwartz, A. Zinsmeister, G. Vance, 1998, American journal of medical genetics.

A case of de novo partial tetrasomy of distal 6p and review of the literature

E. Farrow, G. Vance, V. Thurston, 2007, American journal of medical genetics. Part A.

Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update.

John M S Bartlett, Patrick Fitzgibbons, Mitch Dowsett, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A 37-year-old man with a pleural mass.

G. Vance, T. Jones, R. Saxena, 2005, Archives of pathology & laboratory medicine.

Reply to E.A. Rakha et al.

E. Perez, M. Dowsett, M. Hammond, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Update o n L ate R elapse o f G erm C ell T umor: A C linical a nd Molecular A nalysis

Sin-Ho Jung, N. Heerema, T. Ulbright, 2003 .

Rapid quantification of underivatized alloisoleucine and argininosuccinate using mixed-mode chromatography with tandem mass spectrometry.

B. Graham, G. Vance, Z. Ammous, 2019, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Urorectal septum malformation sequence: report of thirteen additional cases and review of the literature.

M. Bull, D. Weaver, G. Vance, 1997, American journal of medical genetics.

Combined DOG1 and Mammaglobin Immunohistochemistry Is Comparable to ETV6-breakapart Analysis for Differentiating Between Papillary Cystic Variants of Acinic Cell Carcinoma and Mammary Analogue Secretory Carcinoma

G. Vance, Caroline A. Miller, P. Edwards, 2017, International journal of surgical pathology.

Multiplex PCR: critical parameters and step-by-step protocol.

N. Heerema, G. Vance, O. Henegariu, 1997, BioTechniques.

The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression

Ying Guo, Mark Kelley, R. Hromas, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of multiple 12p rearrangements in testicular germ cell tumor cell line 833K and its subclone 64CP by chromosome microdissection.

G. Sledge, N. Heerema, G. Vance, 1998, Cancer genetics and cytogenetics.

A brother and sister with the same karyotype: Case report of two siblings with partial 3p duplication and partial 9p deletion and sex reversal

G. Vance, T. Nebesio, Anisha Gohil, 2021, Clinical case reports.

Extensive analysis of mosaicism in a case of Turner syndrome: the experience of 287 cytogenetic laboratories. College of American Pathologists/American College of Medical Genetics Cytogenetics Resource Committee.

G. Vance, A. Brothman, M. Butler, 1999, Archives of pathology & laboratory medicine.

Triple-color FISH analysis of 12p amplification in testicular germ-cell tumors using 12p band-specific painting probes

N. Heerema, G. Vance, M. Pera, 1998, Journal of Molecular Medicine.

A case with mosaic di-, tetra-, and octacentric ring Y chromosomes.

N. Heerema, G. Vance, O. Henegariu, 1997, American journal of medical genetics.

A report of three patients with an interstitial deletion of chromosome 15q24

A. Cherry, O. Abdul-Rahman, G. Vance, 2005, American journal of medical genetics. Part A.

Phenotypic variability in trisomy 13 mosaicism: Two new patients and literature review

D. Weaver, G. Vance, Christopher B. Griffith, 2009, American journal of medical genetics. Part A.

Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update.

John M S Bartlett, Patrick Fitzgibbons, Lisa M McShane, 2018, Archives of pathology & laboratory medicine.

Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update.

John M S Bartlett, Patrick Fitzgibbons, Lisa M McShane, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Genetic heterogeneity in HER2 testing in breast cancer: panel summary and guidelines.

Raymond R Tubbs, Patrick L Fitzgibbons, K. Bloom, 2009, Archives of pathology & laboratory medicine.

Potential role of hematopoietic stem cell transplantation in children with secondary acute lymphocytic leukemia

G. Vance, F. Smith, P. Kotylo, 2002, Bone Marrow Transplantation.

Cancer-associated alteration of pericentromeric heterochromatin may contribute to chromosome instability

G. Vance, D. Schindelhauer, B. Herbert, 2012, Oncogene.

Small Marker Chromosome Identification in Metaphase and Interphase Using Centromeric Multiplex FISH (CM-FISH)

P. Bray-Ward, D. Ward, S. Artan, 2001, Laboratory Investigation.

Mild "duplication 6q syndrome": a case with partial trisomy (6)(q23.3q25.3).

N. Heerema, G. Vance, O. Henegariu, 1997, American journal of medical genetics.

Characterization of gains, losses, and regional amplification in testicular germ cell tumor cell lines by comparative genomic hybridization.

Sin-Ho Jung, N. Heerema, G. Vance, 2004, Cancer Genetics and Cytogenetics.

Cytogenetics/cytogenomics

G. Vance, 2020, Rodak's Hematology.

Two Patients with Complex Rearrangements Suggestive of Germline Chromoanagenesis

A. Breman, G. Vance, J. Hodge, 2021, Cytogenetic and Genome Research.

Clinical outcome and follow-up of the first reported case of Russell-Silver syndrome with the unique combination of maternal uniparental heterodisomy 7 and mosaic trisomy 7.

Soma Das, D. Weaver, G. Vance, 2005, Birth defects research. Part A, Clinical and molecular teratology.

AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia

A. Jankowska, M. Wagenmann, D. Pruss, 2015, Human molecular genetics.

Novel phenotype of 5p13.3-q11.2 duplication resulting from supernumerary marker chromosome 5: implications for management and genetic counseling

B. Landis, S. Ware, M. E. Armstrong, 2018, Molecular Cytogenetics.

Genital anomalies in three male siblings with Simpson–Golabi–Behmel syndrome

G. Vance, Christopher B. Griffith, Richard C. Probert, 2009, American journal of medical genetics. Part A.

Turner syndrome (45x) with clitoromegaly.

G. Vance, E. Eugster, M. Kaefer, 2003, The Journal of urology.

An Adolescent with a Rare De Novo Distal Trisomy 6p and Distal Monosomy 6q Chromosomal Combination

D. Weaver, G. Vance, E. Conboy, 2020, Case reports in genetics.

Cytogenetic heteromorphisms: survey results and reporting practices of giemsa-band regions that we have pondered for years.

S. Patil, G. Vance, A. Brothman, 2006, Archives of pathology & laboratory medicine.

Long-term disease-free survival after nonmyeloablative cyclophosphamide/fludarabine conditioning and related/unrelated allotransplantation for acute myeloid leukemia/myelodysplasia

K. Cornetta, R. Hromas, G. Vance, 2010, Bone Marrow Transplantation.

Acute graft‐versus‐host disease of the lung after liver transplantation

O. Cummings, P. Kwo, G. Vance, 2002, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

Duplication of 18q21.32–q22.3 identified in a stillborn and two relatives with minimal dysmorphic features

D. Weaver, G. Vance, Karrie A. Hines, 2012, American journal of medical genetics. Part A.

Cyclophosphamide/fludarabine nonmyeloablative allotransplant for acute myeloid leukemia

R. Nelson, S. Perkins, G. Vance, 2015, American journal of hematology.

Klinefelter's Syndrome with Maternal Uniparental Disomy X, Interstitial Xp22.31 Deletion, X-linked Ichthyosis, and Severe Central Nervous System Regression

D. Weaver, G. Vance, L. Walsh, 2020, Journal of Pediatric Genetics.

Chronic myelomonocytic leukemia: the role of bone marrow biopsy immunohistology

M. Czader, G. Vance, Gail H Vance, 2006, Modern Pathology.

Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial.

A. Cherry, M. Tallman, S. Richards, 2005, Blood.

Prevalence of maternal cell contamination in amniotic fluid samples

G. Vance, M. Lee, S. Dlouhy, 2017, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

Clinical laboratory assays for HER-2/neu amplification and overexpression: quality assurance, standardization, and proficiency testing.

R. Nagle, G. Vance, A. Brothman, 2002, Archives of pathology & laboratory medicine.

Malignant gastrointestinal neuroectodermal tumour arising in the extrahepatic bile ducts; a rare neoplasm in an unusual anatomic location

G. Vance, Chen Zhang, A. Al-Hader, 2022, BMJ Case Reports.

FDA's draft guidance on laboratory‐developed tests increases clinical and economic risk to adoption of pharmacogenetic testing

G. Vance, D. Flockhart, K. Levy, 2015, Journal of clinical pharmacology.

Most primary central nervous system diffuse large B-cell lymphomas occurring in immunocompetent individuals belong to the nongerminal center subtype: a retrospective analysis of 31 cases

M. Czader, G. Vance, E. Hattab, 2010, Modern Pathology.

Genome-Wide Association Studies for Taxane-Induced Peripheral Neuropathy in ECOG-5103 and ECOG-1199

Daniel L. Koller, Lang Li, G. Sledge, 2015, Clinical Cancer Research.

Report of new haplotype for ABCC2 gene: rs17222723 and rs8187718 in cis.

Daniel L. Koller, T. Skaar, G. Vance, 2015, Journal of Molecular Diagnostics.

Cytogenetic analysis and construction of a BAC contig across a common neocentromeric region from 9p

S. Schwartz, G. Vance, D. V. Van Dyke, 2001, Chromosoma.

Cytogenetic findings of a child with transcobalamin II deficiency.

N. Heerema, G. Vance, M. Moncino, 1993, American journal of medical genetics.

Fatal melanoma with a novel MYO5A‐BRAF fusion and small associated conventional nevus: A case report and review of literature

G. Vance, A. Alomari, Hannah Clark, 2022, Journal of cutaneous pathology.

Glioblastoma occurring at the site of a previous medulloblastoma following a 5‐year remission period

D. Brat, G. Vance, E. Hattab, 2012, Neuropathology : official journal of the Japanese Society of Neuropathology.

Cryptic Translocation Identification in Human and Mouse Using Several Telomeric Multiplex FISH (TM-FISH) Strategies

J. Korenberg, P. Bray-Ward, D. Ward, 2001, Laboratory Investigation.

Fluorescence in situ hybridization (FISH) as an aid for the diagnosis of graft-versus-host disease in two multivisceral organ transplant patients.

G. Vance, R. Vianna, N. Mousdicas, 2013, The American Journal of dermatopathology.

Fluorescence In Situ Hybridization (FISH) as an Aid for the Diagnosis of Graft-Versus-Host Disease in TwoMultivisceral Organ Transplant Patients

G. Vance, R. Vianna, N. Mousdicas, 2022 .

Independent Prognostic Significance of Monosomy 17 and Impact of Karyotype Complexity in Monosomal Karyotype/Complex Karyotype Acute Myeloid Leukemia: Results from Four ECOG-ACRIN Prospective Therapeutic Trials.

A. Cherry, M. Tallman, G. Vance, 2017, Leukemia research.

Hydranencephaly in a newborn with a FLVCR2 mutation and prenatal exposure to cocaine.

G. Vance, Luis Fernando González Escobar, M. Tucker, 2015, Birth defects research. Part A, Clinical and molecular teratology.

College of american pathologists proposal for the oversight of laboratory-developed tests.

G. Vance, Gail H Vance, 2011, Archives of pathology & laboratory medicine.

Positive and negative professionalism experiences of genetic counseling students in the United States and Canada

L. Wetherill, G. Vance, Wilfredo Torres‐Martinez, 2020, Journal of genetic counseling.

Redefining the risks of prenatally ascertained supernumerary marker chromosomes: a collaborative study

S. Schwartz, U. Surti, L. Christ, 2006, Journal of Medical Genetics.

De novo 10q22 interstitial deletion

D. Weaver, G. Vance, J. Hartsfield, 1999, Journal of medical genetics.

HER-2/neu expression in germ cell tumours

K. Miller, L. Cheng, G. Vance, 2002, Journal of clinical pathology.

49,XXXXY: a distinct phenotype. Three new cases and review.

Jennifer Peet, D. Weaver, G. Vance, 1998, Journal of medical genetics.

Prognostic and Predictive Value of Tumor Vascular Endothelial Growth Factor Gene Amplification in Metastatic Breast Cancer Treated with Paclitaxel with and without Bevacizumab; Results from ECOG 2100 Trial

R. Gray, E. Perez, Lang Li, 2013, Clinical Cancer Research.

Signet-ring cell lymphoma: clinicopathologic, immunohistochemical, and fluorescence in situ hybridization studies of 7 cases.

G. Vance, M. Nassiri, Jiehao Zhou, 2017, Annals of diagnostic pathology.

Partial trisomy 2q: Report of a patient with dup (2)(q33.1q35)

G. Vance, J. Szymańska, V. Thurston, 2005, American journal of medical genetics. Part A.

The human A1 adenosine receptor: ligand binding properties, sites of somatic expression and chromosomal localization

S. Rivkees, G. Vance, M. Lasbury, 1995, Endocrine.

Partners with reciprocal translocations: genetic counseling for the ‘double translocation’

G. Vance, J. Hartsfield, L. Cook, 1998, Clinical genetics.

Laboratory and Clinical Implications of Incidental and Secondary Germline Findings During Tumor Testing.

Marilyn M. Li, Brad W Jensen, J. Myles, 2021, Archives of pathology & laboratory medicine.

Improvement of diagnosis in children with Burkitt lymphoma in Kenya: feasibility study for the implementation of fluorescence in situ hybridisation testing for MYC and the MYC/IGH translocation

G. Vance, A. Moormann, T. Vik, 2023, Ecancermedicalscience.

Cytogenetics: a short review and update.

G. Vance, 1998, Cancer investigation.

Toward quality assurance for metaphase FISH: a multi-center experience.

S. Schwartz, G. Vance, G. Dewald, 1996, American journal of medical genetics.

Detection of recurrent cytogenetic abnormalities in acute lymphoblastic and myeloid leukemias using fluorescence in situ hybridization.

G. Vance, 2013, Methods in molecular biology.

Expanding the genotype–phenotype correlation in subtelomeric 19p13.3 microdeletions using high resolution clinical chromosomal microarray analysis

P. Stankiewicz, Ankita Patel, M. Bull, 2013, American journal of medical genetics. Part A.

Genome-Wide Association Studies for Taxane-Induced Peripheral Neuropathy in ECOG-5103 and ECOG-1199

Daniel L. Koller, Lang Li, G. Sledge, 2015, Clinical Cancer Research.

Luminal subtypes predict improved survival following central nervous system metastasis in patients with surgically managed metastatic breast carcinoma.

Andrea L. Wiens, Liang Cheng, S. Badve, 2014, Archives of pathology & laboratory medicine.

VEGFA amplification/deletion in human breast tumors.

G. Sledge, S. Badve, K. Nielsen, 2010 .

Multiplex PCR: critical parameters and step-by-step protocol.

N. Heerema, G. Vance, O. Henegariu, 1997, BioTechniques.

Phase I study of everolimus (RAD001) with irinotecan (Iri) and cetuximab (C) in second-line metastatic colorectal cancer (mCRC): Hoosier Oncology Group GI05-102-Final report.

J. Picus, G. Vance, E. Chiorean, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.