Choel Kim

发表

The genetic basis of DOORS syndrome: an exome-sequencing study

Jonathan E. Dickerson, Ariana E. Giuliano, J. Wiszniewska, 2014, The Lancet Neurology.

Dynamics of signaling by PKA.

Susan S. Taylor, D. Vigil, Jian Wu, 2005, Biochimica et biophysica acta.

A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase.

Bao Q. Pham, Susan S. Taylor, N. Xuong, 2006, Molecular cell.

Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design.

Susan S. Taylor, Simon H. J. Brown, Jian Wu, 2008, Biochimica et biophysica acta.

DIRAS3 regulates the autophagosome initiation complex in dormant ovarian cancer cells

D. Levine, W. Liao, Choel Kim, 2014, Autophagy.

Switching Cyclic Nucleotide-Selective Activation of Cyclic Adenosine Monophosphate-Dependent Protein Kinase Holoenzyme Reveals Distinct Roles of Tandem Cyclic Nucleotide-Binding Domains.

Choel Kim, C. Lim, F. Herberg, 2017, ACS chemical biology.

Rational design of a PKA-based sensor for cGMP

Choel Kim, C. Lim, F. Herberg, 2015, BMC Pharmacology and Toxicology.

Prevention of PKG1α oxidation augments cardioprotection in the stressed heart.

Dong I. Lee, D. Kass, Choel Kim, 2015, The Journal of clinical investigation.

Structural basis for selective inhibition of human PKG Iα by the balanol-like compound N46

B. Sankaran, Choel Kim, D. Casteel, 2018, The Journal of Biological Chemistry.

Structures of cGMP-Dependent Protein Kinase (PKG) Iα Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability.

P. Zwart, Choel Kim, D. Casteel, 2015, Biochemistry.

Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections.

M. Rieder, J. Shendure, D. Nickerson, 2013, American journal of human genetics.

A substitution in cGMP-dependent protein kinase 1 associated with aortic disease induces an active conformation in the absence of cGMP

Sheng Li, Choel Kim, R. Pilz, 2020, The Journal of Biological Chemistry.

Crystal Structure of the cGMP-dependent Protein Kinase II Leucine Zipper and Rab11b Protein Complex Reveals Molecular Details of G-kinase-specific Interactions*♦

Choel Kim, D. Casteel, K. Yuasa, 2014, The Journal of Biological Chemistry.

Natriuretic peptides protect against apoptosis and increase cGMP around 1 cardiomyocyte mitochondria 2

Choel Kim, F. Levy, K. W. Andressen, 2022 .

Neutron Diffraction Reveals Hydrogen Bonds Critical for cGMP-Selective Activation: Insights for cGMP-Dependent Protein Kinase Agonist Design

B. Sankaran, Choel Kim, G. Huang, 2014, Biochemistry.

Structure of D-AKAP2:PKA RI complex: insights into AKAP specificity and selectivity.

Susan S. Taylor, Choel Kim, Lirong Chen, 2010, Structure.

Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures.

Susan S. Taylor, Simon H. J. Brown, Jian Wu, 2009, Journal of molecular biology.

DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1

Amy M. Hurwitz, R. Bast, T. Palzkill, 2019, Cancers.

Mechanism of allosteric inhibition in the Plasmodium falciparum cGMP-dependent protein kinase

G. Melacini, Choel Kim, F. Herberg, 2020, The Journal of Biological Chemistry.

p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity

Benjamin D. Sachs, C. Schachtrup, D. Davalos, 2012, Proceedings of the National Academy of Sciences.

Crystal structures of the carboxyl cGMP binding domain of plasmodium falciparum cGMP-dependent protein kinase reveals a novel salt bridge crucial for activation

Choel Kim, J. J. Kim, F. Herberg, 2013, BMC Pharmacology and Toxicology.

Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation

M. Blackman, A. Wernimont, D. Baker, 2019, Proceedings of the National Academy of Sciences.

Realizing the allosteric potential of the tetrameric protein kinase A RIα holoenzyme.

Susan S. Taylor, Jian Wu, Jie Yang, 2011, Structure.

PKA-I Holoenzyme Structure Reveals a Mechanism for cAMP-Dependent Activation

Susan S. Taylor, Choel Kim, Cecilia Y. Cheng, 2007, Cell.

Dynamic Binding of PKA Regulatory Subunit RIα

Susan S. Taylor, J. Mccammon, J. Gullingsrud, 2006 .

Dynamic binding of PKA regulatory subunit RI alpha.

Susan S. Taylor, J. Mccammon, J. Gullingsrud, 2006, Structure.

Crystal Structure of a Complex Between the Catalytic and Regulatory (RIα) Subunits of PKA

Nguyen-Huu Xuong, Susan S. Taylor, N. Xuong, 2005, Science.

AMPK and Endothelial Nitric Oxide Synthase Signaling Regulates K-Ras Plasma Membrane Interactions via Cyclic GMP-Dependent Protein Kinase 2

Priyanka Prakash, A. Gorfe, Dharini van der Hoeven, 2016, Molecular and Cellular Biology.

AMPK and eNOS signaling regulates K-Ras plasma membrane interactions via cGMP-dependent Protein Kinase 2

Priyanka Prakash, A. Gorfe, Kwang-jin Cho, 2016 .

Mutations in Fibronectin Cause a Subtype of Spondylometaphyseal Dysplasia with "Corner Fractures".

V. Sutton, M. Tartaglia, R. Pauli, 2017, American journal of human genetics.

Cyclic nucleotide selectivity of protein kinase G isozymes

Choel Kim, Rajesh Sharma, 2020, Protein science : a publication of the Protein Society.

Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity.

B. Sankaran, Choel Kim, J. J. Kim, 2017, The Biochemical journal.

Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation.

B. Sankaran, S. Arold, Choel Kim, 2016, Structure.

Mechanism of cAMP Partial Agonism in Protein Kinase G (PKG)*♦

Rajeevan Selvaratnam, B. VanSchouwen, G. Melacini, 2015, The Journal of Biological Chemistry.

Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG I.

J. Pflugrath, B. Sankaran, Rajeevan Selvaratnam, 2014, Structure.

The amino terminus of cGMP-dependent protein kinase Iβ increases the dynamics of the protein's cGMP-binding pockets.

Virgil L. Woods, Sheng Li, Choel Kim, 2011, International journal of mass spectrometry.

Structural Basis of Analog Specificity in PKG I and II.

James C. Campbell, B. Sankaran, Choel Kim, 2017, ACS chemical biology.

Structural basis of cyclic nucleotide selectivity in cGMP dependent protein kinase II

James C. Campbell, B. Sankaran, T. Link, 2015, BMC Pharmacology and Toxicology.

The crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding

P. Zwart, T. Palzkill, J. Headd, 2011, BMC Pharmacology.

Co-Crystal Structures of PKG Iβ (92–227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding

Timothy Palzkill, Gilbert Huang, Jeffrey J Headd, 2011, PloS one.

Discovery and characterization of bromodomain 2–specific inhibitors of BRDT

D. Young, B. Sankaran, M. Matzuk, 2021, Proceedings of the National Academy of Sciences.

Mutational Constraints on Local Unfolding Inhibit the Rheological Adaptation of von Willebrand Factor*

James C. Campbell, L. Benson, B. Sankaran, 2015, The Journal of Biological Chemistry.

Cyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor Design*

Gao Yunfeng, Ganesh S. Anand, Lin Qingsong, 2010, Molecular & Cellular Proteomics.

FRET-based cyclic GMP biosensors measure low cGMP concentrations in cardiomyocytes and neurons

D. Paterson, Choel Kim, F. Levy, 2019, Communications Biology.

FRET-based cyclic GMP biosensors measure low cGMP concentrations in cardiomyocytes and neurons

D. Paterson, Choel Kim, F. Levy, 2019, Communications Biology.

A Crystal Structure of the Cyclic GMP-dependent Protein Kinase Iβ Dimerization/Docking Domain Reveals Molecular Details of Isoform-specific Anchoring*

B. Sankaran, Choel Kim, R. Pilz, 2010, The Journal of Biological Chemistry.

The genetic basis of DOORS syndrome: an exome-sequencing study

Jonathan E. Dickerson, J. Wiszniewska, S. Cheung, 2013 .

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications

James C. Campbell, Dong I. Lee, M. Zaccolo, 2017, BMC Pharmacology and Toxicology.

DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1

Amy M. Hurwitz, R. Bast, T. Palzkill, 2019, Cancers.

FRET-based cyclic GMP biosensors measure low cGMP concentrations in cardiomyocytes and neurons

D. Paterson, Choel Kim, F. Levy, 2019, Communications Biology.

Prevention of PKG1α oxidation augments cardioprotection in the stressed heart.

Dong I. Lee, D. Kass, Choel Kim, 2015, The Journal of clinical investigation.

Mutations in Fibronectin Cause a Subtype of Spondylometaphyseal Dysplasia with "Corner Fractures".

V. Sutton, M. Tartaglia, R. Pauli, 2017, American journal of human genetics.

Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures.

Susan S. Taylor, Simon H. J. Brown, Jian Wu, 2009, Journal of molecular biology.

A Crystal Structure of the Cyclic GMP-dependent Protein Kinase Iβ Dimerization/Docking Domain Reveals Molecular Details of Isoform-specific Anchoring*

B. Sankaran, Choel Kim, R. Pilz, 2010, The Journal of Biological Chemistry.

Structural basis of cyclic nucleotide selectivity in cGMP dependent protein kinase II

James C. Campbell, B. Sankaran, T. Link, 2015, BMC Pharmacology and Toxicology.

Crystal structure of cGMP‐dependent protein kinase Iβ cyclic nucleotide‐binding‐B domain : Rp‐cGMPS complex reveals an apo‐like, inactive conformation

James C. Campbell, B. Sankaran, B. VanSchouwen, 2017, FEBS letters.