K. Itaka

发表

Regulation of Chondrocyte Differentiation by Changing Intercellular Distances Using Type II Collagen Microfibers.

M. Matsusaki, Jinyu Li, N. Sasaki, 2020, ACS biomaterials science & engineering.

K. Itaka, 2016, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Intrathecal injection of a therapeutic gene-containing polyplex to treat spinal cord injury.

Sakae Tanaka, K. Kataoka, K. Itaka, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors.

K. Kataoka, K. Itaka, S. Uchida, 2014, Biomaterials.

Enhanced stability and gene silencing ability of siRNA-loaded polyion complexes formulated from polyaspartamide derivatives with a repetitive array of amino groups in the side chain.

N. Nishiyama, K. Kataoka, K. Itaka, 2012, Biomaterials.

Odd-even effect of repeating aminoethylene units in the side chain of N-substituted polyaspartamides on gene transfection profiles.

Kazunori Kataoka, Nobuhiro Nishiyama, Keiji Itaka, 2011, Journal of the American Chemical Society.

Biodegradable polyamino acid-based polycations as safe and effective gene carrier minimizing cumulative toxicity.

K. Kataoka, K. Itaka, T. Ishii, 2010, Biomaterials.

Enhanced transfection with silica-coated polyplexes loading plasmid DNA.

Yuichi Yamasaki, Kazunori Kataoka, Nobuhiro Nishiyama, 2010, Biomaterials.

Gene delivery with biocompatible cationic polymer: pharmacogenomic analysis on cell bioactivity.

N. Nishiyama, K. Kataoka, K. Itaka, 2007, Biomaterials.

pH-Responsive PEGylated nanogels as targetable and low invasive endosomolytic agents to induce the enhanced transfection efficiency of nonviral gene vectors

K. Kataoka, K. Itaka, Y. Nagasaki, 2007 .

Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles.

Hiroshi Kawaguchi, Tsuyoshi Takato, Kazunori Kataoka, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Lactose-conjugated polyion complex micelles incorporating plasmid DNA as a targetable gene vector system: their preparation and gene transfecting efficiency against cultured HepG2 cells.

Naoki Kanayama, Yuichi Yamasaki, Atsushi Harada, 2004, Journal of controlled release : official journal of the Controlled Release Society.

Polyion complex micelles from plasmid DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer as serum-tolerable polyplex system: physicochemical properties of micelles relevant to gene transfection efficiency.

Kozo Nakamura, K. Kataoka, K. Itaka, 2003, Biomaterials.

Evaluation by fluorescence resonance energy transfer of the stability of nonviral gene delivery vectors under physiological conditions.

Kozo Nakamura, K. Kataoka, K. Itaka, 2002, Biomacromolecules.

mRNA Therapeutics and mRNA Vaccines

K. Itaka, 2021, TRENDS IN THE SCIENCES.

Intranuclear fluorescence resonance energy transfer analysis of plasmid DNA decondensation from nonviral gene carriers

Y. Matsumoto, K. Kataoka, K. Itaka, 2009, The journal of gene medicine.

Combination of chondroitin sulfate and polyplex micelles from Poly(ethylene glycol)-poly{N'-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} block copolymer for prolonged in vivo gene transfection with reduced toxicity.

K. Kataoka, K. Itaka, S. Uchida, 2011, Journal of controlled release : official journal of the Controlled Release Society.

3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cells.

N. Nishiyama, K. Kataoka, K. Itaka, 2009, Biomaterials.

Efficient delivery of bioactive antibodies into the cytoplasm of living cells by charge-conversional polyion complex micelles.

N. Nishiyama, K. Kataoka, K. Itaka, 2010, Angewandte Chemie.

In Vivo Messenger RNA Introduction into the Central Nervous System Using Polyplex Nanomicelle

S. Fukushima, K. Kataoka, K. Itaka, 2013, PloS one.

Prolonged engraftment of transplanted hepatocytes in the liver by transient pro‐survival factor supplementation using ex vivo mRNA transfection

K. Kataoka, K. Itaka, S. Uchida, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Gene transfection to spheroid culture system on micropatterned culture plate by polyplex nanomicelle: a novel platform of genetically-modified cell transplantation

K. Kataoka, K. Itaka, S. Uchida, 2012, Drug Delivery and Translational Research.

mRNA as a Tool for Gene Transfection in 3D Cell Culture for Future Regenerative Therapy

K. Kataoka, K. Itaka, S. Uchida, 2020, Micromachines.

Treatment of ischemic neuronal death by introducing brain-derived neurotrophic factor mRNA using polyplex nanomicelle.

K. Kataoka, K. Itaka, N. Saito, 2021, Biomaterials.

Development of Biodegradable Polycation-Based Inhalable Dry Gene Powders by Spray Freeze Drying

K. Kataoka, Yuko Kobayashi, K. Itaka, 2015, Pharmaceutics.

Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety.

K. Kataoka, K. Itaka, S. Uchida, 2016, Biomaterials.

Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors.

Takahiro Nomoto, K. Toh, Y. Matsumoto, 2014, Biomaterials.

Block/homo polyplex micelle-based GM-CSF gene therapy via intraperitoneal administration elicits antitumor immunity against peritoneal dissemination and exhibits safety potentials in mice and cynomolgus monkeys.

K. Kataoka, K. Itaka, K. Nakano, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Versatile Design of Intracellular Protein-Responsive Translational Regulation System for Synthetic mRNA.

K. Itaka, Hirohide Saito, Hideyuki Nakanishi, 2022, ACS synthetic biology.

A PEG‐Based Biocompatible Block Catiomer with High Buffering Capacity for the Construction of Polyplex Micelles Showing Efficient Gene Transfer toward Primary Cells

S. Fukushima, N. Nishiyama, K. Kataoka, 2006, ChemMedChem.

Enhanced Antibacterial Property of Facet-Engineered TiO2 Nanosheet in Presence and Absence of Ultraviolet Irradiation

K. Itaka, K. Yamashita, S. Ohara, 2019, Materials.

Gene Transfection toward Spheroid Cells on Micropatterned Culture Plates for Genetically-modified Cell Transplantation.

K. Kataoka, K. Itaka, S. Uchida, 2015, Journal of visualized experiments : JoVE.

Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases

K. Kataoka, K. Itaka, S. Uchida, 2015, Scientific Reports.

[Supramolecular nanocarrier for gene and siRNA delivery].

K. Kataoka, K. Itaka, U. Chung, 2006, Nihon rinsho. Japanese journal of clinical medicine.

Polyunsaturated Fatty Acids Selectively Suppress Sterol Regulatory Element-binding Protein-1 through Proteolytic Processing and Autoloop Regulatory Circuit*

K. Kataoka, Y. Izumida, T. Kadowaki, 2010, The Journal of Biological Chemistry.

Bone Morphogenetic Protein 2-Induced Osteoblast Differentiation Requires Smad-Mediated Down-Regulation of Cdk6

Kozo Nakamura, T. Takato, H. Okayama, 2004, Molecular and Cellular Biology.

A nanoparticle system specifically designed to deliver short interfering RNA inhibits tumor growth in vivo.

K. Fujiu, K. Itaka, R. Nagai, 2009, Cancer research.

Corrigendum: Glycogen shortage during fasting triggers liver–brain–adipose neurocircuitry to facilitate fat utilization

K. Kataoka, Y. Izumida, T. Kadowaki, 2013, Nature Communications.

Glycogen shortage during fasting triggers liver–brain–adipose neurocircuitry to facilitate fat utilization

K. Kataoka, Y. Izumida, T. Kadowaki, 2013, Nature Communications.

Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats.

N. Nishiyama, K. Kataoka, K. Itaka, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Influence of Nanobubble Size Distribution on Ultrasound-Mediated Plasmid DNA and Messenger RNA Gene Delivery

K. Tachibana, K. Itaka, L. B. Feril, 2022, Frontiers in Pharmacology.

Improved Brain Expression of Anti-Amyloid β scFv by Complexation of mRNA Including a Secretion Sequence with PEG-based Block Catiomer.

K. Kataoka, K. Itaka, S. Uchida, 2016, Current Alzheimer research.

Treatment of Intervertebral Disk Disease by the Administration of mRNA Encoding a Cartilage-Anabolic Transcription Factor

K. Kataoka, K. Itaka, S. Uchida, 2019, Molecular therapy. Nucleic acids.

Brain Dp140 alters glutamatergic transmission and social behaviour in the mdx52 mouse model of Duchenne muscular dystrophy

F. Muntoni, N. Ichinohe, M. Hoshino, 2022, Progress in Neurobiology.

Anti-Inflammatory Therapy for Temporomandibular Joint Osteoarthritis Using mRNA Medicine Encoding Interleukin-1 Receptor Antagonist

K. Itaka, E. Yada, K. Nozaki, 2022, Pharmaceutics.

Treatment of Bone Defects by Transplantation of Genetically Modified Mesenchymal Stem Cell Spheroids

K. Kataoka, K. Itaka, S. Uchida, 2018, Molecular therapy. Methods & clinical development.

Identification and characterization of the human SOX6 promoter.

Kozo Nakamura, K. Itaka, A. Kan, 2007, Biochemical and biophysical research communications.

Unbiased comparison and modularization identify time-related transcriptomic reprogramming in exercised rat cartilage: Integrated data mining and experimental validation

K. Itaka, Y. Shibata, Jiarui Cui, 2022, Frontiers in Physiology.

A novel osteogenic helioxanthin-derivative acts in a BMP-dependent manner.

Kozo Nakamura, T. Takato, K. Itaka, 2007, Biochemical and biophysical research communications.

Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells.

Kazunori Kataoka, Yukio Nagasaki, Nobuhiro Nishiyama, 2005, Journal of the American Chemical Society.

Introduction to Special Issue: A New Paradigm of Gene Therapy

K. Itaka, 2016, Pharmaceutics.

Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors.

M. Kano, K. Kataoka, K. Itaka, 2012, Biomaterials.

Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly A sequences for effective vaccination.

K. Kataoka, K. Itaka, S. Uchida, 2018, Biomaterials.

Synthetic mRNA for ex vivo therapeutic applications.

K. Itaka, Hideyuki Nakanishi, 2022, Drug metabolism and pharmacokinetics.

Tethered PEG Crowdedness Determining Shape and Blood Circulation Profile of Polyplex Micelle Gene Carriers

Takahiro Nomoto, K. Toh, Y. Matsumoto, 2013 .

Combined CatWalk Index: an improved method to measure mouse motor function using the automated gait analysis system

Kazunori Kataoka, Samuel T. Crowley, Keiji Itaka, 2018, BMC Research Notes.

Enhancement of Motor Function Recovery after Spinal Cord Injury in Mice by Delivery of Brain-Derived Neurotrophic Factor mRNA

K. Kataoka, K. Itaka, S. Uchida, 2019, Molecular therapy. Nucleic acids.

Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles.

K. Kataoka, K. Itaka, S. Uchida, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Modulated protonation of side chain aminoethylene repeats in N-substituted polyaspartamides promotes mRNA transfection.

Takahiro Nomoto, N. Nishiyama, K. Kataoka, 2014, Journal of the American Chemical Society.

Effective transgene expression without toxicity by intraperitoneal administration of PEG-detachable polyplex micelles in mice with peritoneal dissemination.

N. Nishiyama, K. Kataoka, K. Itaka, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Fascicular constriction in the anterior interosseous nerve and other motor branches of the median nerve

K. Itaka, Y. Tajiri, A. Nagano, 1999, Muscle & nerve.

Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment

S. Fukushima, K. Kataoka, K. Itaka, 2016, Scientific Reports.

Screening of mRNA Chemical Modification to Maximize Protein Expression with Reduced Immunogenicity

K. Kataoka, K. Itaka, S. Uchida, 2015, Pharmaceutics.

Enhancement of angiogenesis through stabilization of hypoxia-inducible factor-1 by silencing prolyl hydroxylase domain-2 gene.

K. Miyazono, M. Kano, N. Nishiyama, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain

Y. Anraku, K. Toh, Y. Matsumoto, 2017, Nature Communications.

Muscle-targeted hydrodynamic gene introduction of insulin-like growth factor-1 using polyplex nanomicelle to treat peripheral nerve injury.

K. Kataoka, K. Itaka, S. Uchida, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Efficient Messenger RNA Delivery to the Kidney Using Renal Pelvis Injection in Mice

S. Kawakami, K. Itaka, Natsuko Oyama, 2021, Pharmaceutics.

Progress and prospects of polyplex nanomicelles for plasmid DNA delivery.

K. Kataoka, K. Itaka, 2011, Current gene therapy.

Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle.

Pilhan Kim, S. Yun, K. Kataoka, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Recent development of nonviral gene delivery systems with virus-like structures and mechanisms.

K. Kataoka, K. Itaka, 2009, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Raman spectroscopic insight into osteoarthritic cartilage regeneration by mRNA therapeutics encoding cartilage-anabolic transcription factor Runx1

K. Itaka, E. Marin, G. Pezzotti, 2022, Materials today. Bio.

Development of Synthetic mRNAs Encoding Split Cytotoxic Proteins for Selective Cell Elimination Based on Specific Protein Detection

K. Itaka, Hideyuki Nakanishi, Kendall Free, 2023, Pharmaceutics.

Efficient mRNA Delivery with Lyophilized Human Serum Albumin-Based Nanobubbles

K. Tachibana, K. Itaka, L. B. Feril, 2023, Nanomaterials.

Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain

Y. Anraku, K. Toh, Y. Matsumoto, 2017, Nature Communications.

KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.

K. Kataoka, Y. Izumida, T. Kadowaki, 2016, Cell reports.

Synthetic Polyamines to Regulate mRNA Translation through the Preservative Binding of Eukaryotic Initiation Factor 4E to the Cap Structure.

N. Nishiyama, K. Kataoka, K. Itaka, 2016, Journal of the American Chemical Society.

In situ single cell observation by fluorescence resonance energy transfer reveals fast intra‐cytoplasmic delivery and easy release of plasmid DNA complexed with linear polyethylenimine

Yuichi Yamasaki, Hiroshi Kawaguchi, Atsushi Harada, 2004, The journal of gene medicine.

SRC‐1 Is Necessary for Skeletal Responses to Sex Hormones in Both Males and Females

Kozo Nakamura, P. Chambon, Takahiro Matsumoto, 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Treatment of neurological disorders by introducing mRNA in vivo using polyplex nanomicelles.

K. Kataoka, K. Itaka, T. Yamasoba, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Treatment of spinal cord injury by an advanced cell transplantation technology using brain-derived neurotrophic factor-transfected mesenchymal stem cell spheroids.

Sakae Tanaka, K. Kataoka, K. Itaka, 2016, Biomaterials.

An injectable spheroid system with genetic modification for cell transplantation therapy.

Yu Matsumoto, Satoshi Uchida, Kazunori Kataoka, 2014, Biomaterials.

Enhanced gene expression promoted by the quantized folding of pDNA within polyplex micelles.

K. Kataoka, K. Itaka, K. Osada, 2012, Biomaterials.

Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer

Kazunori Kataoka, Nobuhiro Nishiyama, Hidenori Takahashi, 2005, Nature materials.

Enhanced Growth Inhibition of Hepatic Multicellular Tumor Spheroids by Lactosylated Poly(ethylene glycol)‐siRNA Conjugate Formulated in PEGylated Polyplexes

Kazunori Kataoka, Yukio Nagasaki, Nobuhiro Nishiyama, 2007, ChemMedChem.

Scaffolds for Skeletal Regeneration

Kozo Nakamura, N. Nishiyama, K. Kataoka, 2007 .

PEGylated polyplex with optimized PEG shielding enhances gene introduction in lungs by minimizing inflammatory responses.

K. Kataoka, K. Itaka, S. Uchida, 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors.

Yuichi Yamasaki, Kazunori Kataoka, Nobuhiro Nishiyama, 2008, Journal of the American Chemical Society.

Polyion complex micelles of pDNA with acetal-poly(ethylene glycol)-poly(2-(dimethylamino)ethyl methacrylate) block copolymer as the gene carrier system: physicochemical properties of micelles relevant to gene transfection efficacy.

N. Nishiyama, K. Kataoka, K. Itaka, 2004, Biomacromolecules.

Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble flt-1.

K. Miyazono, M. Kano, N. Nishiyama, 2010, Molecular pharmaceutics.

A tadpole-shaped gene carrier with distinct phase segregation in a ternary polymeric micelle.

K. Kataoka, K. Itaka, S. Uchida, 2015, Soft matter.

The state of the art of nanobioscience in Japan

S. Ueno, J. Ando, H. Fujita, 2006, IEEE Transactions on NanoBioscience.

Gene transfection to spheroid culture system on micropatterned culture plate by polyplex nanomicelle: a novel platform of genetically-modified cell transplantation

K. Kataoka, K. Itaka, S. Uchida, 2012, Drug Delivery and Translational Research.

Administration of mRNA-Nanomedicine-Augmented Calvarial Defect Healing via Endochondral Ossification

K. Itaka, Guan-Yu Zhuo, Chin-Yu Lin, 2023, Pharmaceutics.

Polyplex micelles with cyclic RGD peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular trafficking.

Yu Matsumoto, Yuichi Yamasaki, Kazunori Kataoka, 2008, Molecular pharmaceutics.

Enhancement of bone regeneration by coadministration of angiogenic and osteogenic factors using messenger RNA

N. Wakabayashi, K. Itaka, K. Nozaki, 2023, Inflammation and Regeneration.

Smart polymeric micelles as nanocarriers for oligonucleotides and siRNA delivery.

N. Nishiyama, K. Kataoka, K. Itaka, 2005, Nucleic acids symposium series.

Muscle-targeted hydrodynamic gene introduction of insulin-like growth factor-1 using polyplex nanomicelle to treat peripheral nerve injury.

K. Kataoka, K. Itaka, S. Uchida, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Toroidal Packaging of pDNA into Block Ionomer Micelles Exerting Promoted in Vivo Gene Expression.

K. Kataoka, K. Itaka, S. Uchida, 2015, Biomacromolecules.

Odd-even effect of repeating aminoethylene units in the side chain of N-substituted polyaspartamides on gene transfection profiles.

N. Nishiyama, K. Kataoka, K. Itaka, 2011, Journal of the American Chemical Society.

Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly A sequences for effective vaccination.

K. Kataoka, K. Itaka, S. Uchida, 2018, Biomaterials.