D. Eyre

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Collagen: molecular diversity in the body's protein scaffold

D. Eyre, D R Eyre, 1980, Science.

Effects of proteoglycan extraction on the tensile behavior of articular cartilage

V C Mow, V. Mow, D. Eyre, 1990, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Viscoelastic shear properties of articular cartilage and the effects of glycosidase treatments

V C Mow, V. Mow, T. Koob, 1993, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Type XI or 1α2α3α Collagen

D. Eyre, 1987 .

Articular cartilage and changes in Arthritis: Collagen of articular cartilage

D. Eyre, 2001, Arthritis research.

Cross-linking in collagen and elastin.

P. Gallop, D. Eyre, M. Paz, 1984, Annual review of biochemistry.

Molecular basis and clinical application of biological markers of bone turnover.

D. Eyre, M. Calvo, C. Gundberg, 1996, Endocrine reviews.

Collagen cross-links

D. Eyre, Jiann-Jiu Wu, 2005 .

Collagen polymorphisms of the intervertebral disc.

D. Eyre, Y. Matsui, J.-J. Wu, 2002, Biochemical Society transactions.

Post-translationally Abnormal Collagens of Prolyl 3-Hydroxylase-2 Null Mice Offer a Pathobiological Mechanism for the High Myopia Linked to Human LEPREL1 Mutations*

Brendan H. Lee, D. Eyre, David M. Hudson, 2015, The Journal of Biological Chemistry.

Differential Effects of Collagen Prolyl 3-Hydroxylation on Skeletal Tissues

B. Dawson, O. Lichtarge, Brendan H. Lee, 2014, PLoS genetics.

Peptidyl 3-hydroxyproline binding properties of type I collagen suggest a function in fibril supramolecular assembly.

D. Eyre, D. Cohn, David M. Hudson, 2012, Biochemistry.

Mutations in PPIB (cyclophilin B) delay type I procollagen chain association and result in perinatal lethal to moderate osteogenesis imperfecta phenotypes.

P. Byers, D. Russell, B. Burton, 2011, Human molecular genetics.

Insights on the Evolution of Prolyl 3-Hydroxylation Sites from Comparative Analysis of Chicken and Xenopus Fibrillar Collagens

D. Eyre, David M. Hudson, D. Hudson, 2011, PloS one.

Location of 3-Hydroxyproline Residues in Collagen Types I, II, III, and V/XI Implies a Role in Fibril Supramolecular Assembly*

D. Eyre, David M. Hudson, Jiann-Jiu Wu, 2009, The Journal of Biological Chemistry.

Cartilage expression of a type II collagen mutation in an inherited form of osteoarthritis associated with a mild chondrodysplasia.

R. Moskowitz, D. Eyre, M. Weis, 1991, The Journal of clinical investigation.

Quantitation of hydroxypyridinium crosslinks in collagen by high-performance liquid chromatography.

T. Koob, D. Eyre, K. V. Van Ness, 1984, Analytical biochemistry.

Identification of cross-linking sites in bovine cartilage type IX collagen reveals an antiparallel type II-type IX molecular relationship and type IX to type IX bonding.

D. Eyre, Jiann-Jiu Wu, J. Wu, 1992, The Journal of biological chemistry.

The effect of calcium supplementation on the circadian rhythm of bone resorption.

R. Eastell, D. Eyre, P. Shao, 1994, The Journal of clinical endocrinology and metabolism.

A multicenter trial of low dose gallium nitrate in patients with advanced Paget's disease of bone

E. Siris, D. Eyre, F. Singer, 1995 .

The hydroxypyridinium crosslinks of skeletal collagens: their measurement, properties and a proposed pathway of formation.

D. Eyre, H. Oguchi, David R. Eyre, 1980, Biochemical and biophysical research communications.

Excessive TGFβ signaling is a common mechanism in Osteogenesis Imperfecta

B. Dawson, C. Ambrose, Y. Ishikawa, 2014, Nature Medicine.

Isolation of a murine osteoclast colony-stimulating factor.

D. Eyre, W. Osborne, M. Lee, 1991, Proceedings of the National Academy of Sciences of the United States of America.

A 92 kDa gelatinase (MMP-9) cleavage site in native type V collagen.

D. Eyre, C. Niyibizi, J. Wu, 1994, Biochemical and biophysical research communications.

Pediatric Outcomes Data Collection Instrument is a Useful Patient-Reported Outcome Measure for Physical Function in Children with Osteogenesis Imperfecta

J. Krischer, F. Glorieux, Mahim Jain, 2019, Genetics in Medicine.

A specific immunoassay for monitoring human bone resorption: Quantitation of type I collagen cross‐linked N‐telopeptides in urine

D. Eyre, F. Singer, D. Hanson, 1992, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

3-D ultrastructure and collagen composition of healthy and overloaded human tendon: evidence of tenocyte and matrix buckling

Henning Langberg, David Eyre, Michael Kjaer, 2014, Journal of anatomy.

Type III Collagen, a Fibril Network Modifier in Articular Cartilage*

D. Eyre, Jiann-Jiu Wu, M. Weis, 2010, The Journal of Biological Chemistry.

Dominant‐negative SOX9 mutations in campomelic dysplasia

M. Bamshad, D. Eyre, D. Krakow, 2019, Human mutation.

Murine tendon function is adversely affected by aggrecan accumulation due to the knockout of ADAMTS5

J. Galante, D. Eyre, J. Sandy, 2012, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Analysis of cartilage biomarkers in the early phases of canine experimental osteoarthritis.

D. Eyre, A. Poole, J. Matyas, 2004, Arthritis and rheumatism.

Monitoring bone resorption in early postmenopausal women by an immunoassay for cross‐linked collagen peptides in urine

H. Genant, D. Eyre, B. Gertz, 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Streaming potentials: A sensitive index of enzymatic degradation in articular cartilage

A. Grodzinsky, T. Koob, D. Eyre, 1987, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Recent developments in cartilage research

D. Eyre, T. Pietka, Jiann-Jiu Wu, 2002 .

The specificity of collagen cross-links as markers of bone and connective tissue degradation.

D. Eyre, 1995, Acta orthopaedica Scandinavica. Supplementum.

Report of five novel and one recurrentCOL2A1 mutations with analysis of genotype-phenotype correlation in patients with a lethal type II collagen disorder

G. Mortier, D. Rimoin, D. Eyre, 2000, Journal of medical genetics.

Bone biomarkers as tools in osteoporosis management.

D. Eyre, 1997, Spine.

Collagen type IX from human cartilage: a structural profile of intermolecular cross-linking sites.

D. Eyre, J. Wu, M. Diab, 1996, The Biochemical journal.

Loss of Type I Collagen Telopeptide Lysyl Hydroxylation Causes Musculoskeletal Abnormalities in a Zebrafish Model of Bruck Syndrome

Ronald Y. Kwon, D. Eyre, A. De Paepe, 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The Helix-II epitope: a cautionary tale from a cartilage biomarker based on an invalid collagen sequence.

D. Eyre, M. Weis, 2009, Osteoarthritis and cartilage.

Differences in Chain Usage and Cross-linking Specificities of Cartilage Type V/XI Collagen Isoforms with Age and Tissue*

D. Eyre, Jiann-Jiu Wu, M. Weis, 2009, Journal of Biological Chemistry.

Connective tissue alterations in Fkbp10-/- mice.

Brendan H. Lee, D. Eyre, Yuqing Chen, 2014, Human molecular genetics.

The effect of short term treatment with alendronate on vertebral density and biochemical markers of bone remodeling in early postmenopausal women.

H. Genant, D. Eyre, B. Gertz, 1993, The Journal of clinical endocrinology and metabolism.

Evidence that serum NTx (collagen-type I N-telopeptides) can act as an immunochemical marker of bone resorption.

D. Eyre, J. Clemens, F. Singer, 1997, Clinical chemistry.

J. O’Kane, D. Eyre, L. Atley, 2006, Osteoarthritis and cartilage.

Proteolysis of human bone collagen by cathepsin K: characterization of the cleavage sites generating by cross-linked N-telopeptide neoepitope.

D. Eyre, J. Mort, L. Atley, 2000, Bone.

Hypercalcemia during the osteogenic phase after rat marrow ablation coincides with increased bone resorption assessed by the NTx marker.

K. Shaffer, D. Eyre, E. Shacter, 2000, Bone.

Osteoclasts generate cross-linked collagen N-telopeptides (NTx) but not free pyridinolines when cultured on human bone.

D. Eyre, S. Apone, M. Y. Lee, 1997, Bone.

Circadian variation in urinary excretion of bone collagen cross‐links

B. Leroux, D. Eyre, Michael D. Martin, 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Longitudinal evaluation of a bone resorption marker in elderly subjects

D. Eyre, H. Kiyak, A. Bollen, 2007, Osteoporosis International.

New biomarkers of bone resorption.

D. Eyre, 1992, The Journal of clinical endocrinology and metabolism.

Changes with age in the urinary excretion of lysyl‐ and hydroxylysylpyridinoline, two new markers of bone collagen turnover

D. Eyre, Lindsay J. Beardsworth, I. Dickson, 1990, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

COPB2 loss of function causes a coatopathy with osteoporosis and developmental delay.

David R. Murdock, Lisa T. Emrick, Alyssa A. Tran, 2021, American journal of human genetics.

Collagen of fibrocartilage: a distinctive molecular phenotype in bovine meniscus

D. Eyre, Jiann-Jiu Wu, J. Wu, 1983, FEBS letters.

Type VI collagen of the intervertebral disc. Biochemical and electron-microscopic characterization of the native protein.

D. Eyre, J. Wu, H. Slayter, 1987, The Biochemical journal.

Articular cartilage collagen: an irreplaceable framework?

D. Eyre, Jiann-Jiu Wu, M. Weis, 2006, European cells & materials.

Matrilin-3 Forms Disulfide-linked Oligomers with Matrilin-1 in Bovine Epiphyseal Cartilage*

D. Eyre, Jiann-Jiu Wu, J. Wu, 1998, The Journal of Biological Chemistry.

Biochemical markers of bone turnover and their association with bone marrow lesions

M. Nevitt, D. Bauer, D. Felson, 2008, Arthritis research & therapy.

Abnormality of type IX collagen in a patient with diastrophic dysplasia.

D. Eyre, F. Shapiro, M. Diab, 1994, American journal of medical genetics.

Collagen cross-linking and bone pathobiology

D. Eyre, David M. Hudson, D. Hudson, 2020 .

The Heterozygous Disproportionate Micromelia (Dmm) Mouse: Morphological Changes in Fetal Cartilage Precede Postnatal Dwarfism and Compared With Lethal Homozygotes Can Explain the Mild Phenotype

L. Bridgewater, D. Eyre, C. Montano, 2008, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Protein consequences of the Col2a1 C-propeptide mutation in the chondrodysplastic Dmm mouse.

D. Eyre, R. J. Fernandes, R. Seegmiller, 2003, Matrix biology : journal of the International Society for Matrix Biology.

Mutations That Alter the Carboxy-Terminal-Propeptide Cleavage Site of the Chains of Type I Procollagen Are Associated With a Unique Osteogenesis Imperfecta Phenotype

P. Byers, E. Duncan, M. Szybowska, 2018, Yearbook of Paediatric Endocrinology.

Prolyl 3-hydroxylase 1 deficiency causes a recessive metabolic bone disorder resembling lethal/severe osteogenesis imperfecta

C. Tifft, Peter A. Smith, D. Eyre, 2007, Nature Genetics.

Bone resorption rates in children monitored by the urinary assay of collagen type I cross-linked peptides.

D. Eyre, A. Bollen, 1994, Bone.

A Transgenic Mouse Model of OI Type V Supports a Neomorphic Mechanism of the IFITM5 Mutation

B. Dawson, Brendan H. Lee, D. Eyre, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Identification of a mutation causing deficient BMP1/mTLD proteolytic activity in autosomal recessive osteogenesis imperfecta

P. Lapunzina, D. Eyre, J. Caparrós-Martín, 2012, Human mutation.

Mutations in the gene encoding the RER protein FKBP65 cause autosomal-recessive osteogenesis imperfecta.

P. Byers, Brendan H. Lee, D. Eyre, 2010, American journal of human genetics.

Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding.

C. Rotimi, D. Eyre, Wei-zhong Chang, 2010, The New England journal of medicine.

Homozygosity for a missense mutation in SERPINH1, which encodes the collagen chaperone protein HSP47, results in severe recessive osteogenesis imperfecta.

P. Byers, D. Eyre, U. Schwarze, 2010, American journal of human genetics.

CRTAP and LEPRE1 mutations in recessive osteogenesis imperfecta

John J. Mitchell, A. Green, P. Byers, 2008, Human mutation.

Deficiency of cartilage-associated protein in recessive lethal osteogenesis imperfecta.

J. Mulvihill, Brendan H. Lee, D. Eyre, 2006, The New England journal of medicine.

Biochemical assessment of bone formation and resorption in acromegaly.

S. Melmed, D. Eyre, F. Singer, 1993, The Journal of clinical endocrinology and metabolism.

Changes in cartilage composition and physical properties due to stromelysin degradation.

L. Bonassar, A. Grodzinsky, D. Eyre, 1995, Arthritis and rheumatism.

Collagen type II differs from type I in native molecular packing.

D. Kirschner, D. Eyre, M. Grynpas, 1980, Biochimica et biophysica acta.

Longitudinal and cross-sectional variability in markers of joint metabolism in patients with knee pain and articular cartilage abnormalities.

E. Thonar, L. Ryd, D. Eyre, 1998, Osteoarthritis and cartilage.

Direct extraction of gelatinases from rat bone.

D. Eyre, A. Bollen, 1993, Connective tissue research.

Identification of hydroxypyridinium cross-linking sites in type II collagen of bovine articular cartilage.

D. Eyre, J. Wu, J. J. Wu, 1984, Biochemistry.

The kyphoscoliotic type of Ehlers-Danlos syndrome (type VI): differential effects on the hydroxylation of lysine in collagens I and II revealed by analysis of cross-linked telopeptides from urine.

D. Eyre, B. Steinmann, P. Shao, 2002, Molecular genetics and metabolism.

Substitution of murine type I collagen A1 3-hydroxylation site alters matrix structure but does not recapitulate osteogenesis imperfecta bone dysplasia.

P. Backlund, D. Eyre, K. Kozloff, 2020, Matrix biology : journal of the International Society for Matrix Biology.

Maturation of Collagen Ketoimine Cross-links by an Alternative Mechanism to Pyridinoline Formation in Cartilage*

D. Eyre, Jiann-Jiu Wu, M. Weis, 2010, The Journal of Biological Chemistry.

Changes in tissue morphology and collagen composition during the repair of cortical bone in the adult chicken.

M. Glimcher, D. Eyre, F. Shapiro, 1980, The Journal of bone and joint surgery. American volume.

Identification of the cartilage α 1(XI) chain in type V collagen from bovine bone

D. Eyre, C. Niyibizi, 1989 .

Long-term treatment of osteopetrosis with recombinant human interferon gamma.

R. Rodriguiz, D. Eyre, W. Ries, 1995, The New England journal of medicine.

New insights on the clinical variability of FKBP10 mutations.

D. Eyre, B. Callewaert, P. Coucke, 2020, European journal of medical genetics.

A Novel Mutation in LEPRE1 That Eliminates Only the KDEL ER- Retrieval Sequence Causes Non-Lethal Osteogenesis Imperfecta

D. Eyre, G. Nishimura, R. Fukuzawa, 2012, PloS one.

Fibrochondrogenesis results from mutations in the COL11A1 type XI collagen gene.

Michael F. Wangler, L. Ala‐Kokko, M. Wangler, 2010, American journal of human genetics.

An RNA-Splicing Mutation (G+s'vSzo) in the Type 11 Collagen Gene (COL2A I) in a Family with Spondyloepiphyseal Dysplasia Congenita

D. Eyre, D. Cohn, M. Weis, 2007 .

Dominant mutations in the type II collagen gene, COL2A1, produce spondyloepimetaphyseal dysplasia, Strudwick type

D. Rimoin, D. Eyre, D. Cohn, 1995, Nature Genetics.

D. Eyre, D. Hudson, M. Weis, 2021, bioRxiv.

P3h3-null and Sc65-null Mice Phenocopy the Collagen Lysine Under-hydroxylation and Cross-linking Abnormality of Ehlers-Danlos Syndrome Type VIA*

Brendan H. Lee, D. Eyre, David M. Hudson, 2017, The Journal of Biological Chemistry.

The development of a mature collagen network in cartilage from human bone marrow stem cells in Transwell culture.

T. Hardingham, D. Eyre, A. Murdoch, 2016, Matrix biology : journal of the International Society for Matrix Biology.

Evolutionary Origins of C-Terminal (GPP)n 3-Hydroxyproline Formation in Vertebrate Tendon Collagen

D. Eyre, David M. Hudson, Jiann-Jiu Wu, 2014, PloS one.

A Role for Prolyl 3-Hydroxylase 2 in Post-translational Modification of Fibril-forming Collagens*

D. Eyre, M. Weis, R. J. Fernandes, 2011, The Journal of Biological Chemistry.

A Novel 3-Hydroxyproline (3Hyp)-rich Motif Marks the Triple-helical C Terminus of Tendon Type I Collagen*

D. Eyre, David M. Hudson, Jiann-Jiu Wu, 2011, The Journal of Biological Chemistry.

Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta

L. Ala‐Kokko, P. Blank, J. Zimmerberg, 2016, PLoS genetics.

Connective tissue alterations in Fkbp10 2 / 2 mice

Brendan H. Lee, D. Eyre, Yuqing Chen, 2014 .

Mutations in FKBP10, which result in Bruck syndrome and recessive forms of osteogenesis imperfecta, inhibit the hydroxylation of telopeptide lysines in bone collagen.

P. Byers, K. Conneely, G. Pals, 2013, Human molecular genetics.

Absence of FKBP10 in recessive type XI osteogenesis imperfecta leads to diminished collagen cross‐linking and reduced collagen deposition in extracellular matrix

D. Eyre, S. Leikin, E. L. Mertz, 2012, Human mutation.

Deficiency of CRTAP in non‐lethal recessive osteogenesis imperfecta reduces collagen deposition into matrix

D. Eyre, S. Leikin, S. Viglio, 2012, Clinical genetics.

Generalized Connective Tissue Disease in Crtap-/- Mouse

P. Byers, Brendan H. Lee, D. Eyre, 2010, PloS one.

Spondylocheiro dysplastic form of the Ehlers-Danlos syndrome--an autosomal-recessive entity caused by mutations in the zinc transporter gene SLC39A13.

N. Elçioglu, D. Eyre, B. Albrecht, 2008, American journal of human genetics.

Sp1 Family of Transcription Factors Regulates the Human α2 (XI) Collagen Gene (COL11A2) in Saos‐2 Osteoblastic Cells

D. Eyre, T. Fujita, T. Komori, 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Diclofenac sodium inhibits bone resorption in postmenopausal women.

R. Eastell, D. Eyre, B. Hollis, 1994, The American journal of medicine.

Osteogenesis imperfecta. The position of substitution for glycine by cysteine in the triple helical domain of the pro alpha 1(I) chains of type I collagen determines the clinical phenotype.

P. Byers, J. Graham, D. Eyre, 1989, The Journal of clinical investigation.

Bone remodeling and bone mineral density during pregnancy

D. Eyre, M. Soules, C. Chesnut, 2003, Archives of Gynecology and Obstetrics.

Zebrafish type I collagen mutants faithfully recapitulate human type I collagenopathies

Ronald Y. Kwon, S. Fisher, D. Eyre, 2018, Proceedings of the National Academy of Sciences.

Recent developments in cartilage research: matrix biology of the collagen II/IX/XI heterofibril network.

D. Eyre, T. Pietka, M. Weis, 2001, Biochemical Society transactions.

Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia.

C. Zeiss, V. Monnier, A. Perkins, 2014, Bone.

The post-translational phenotype of collagen synthesized by SAOS-2 osteosarcoma cells.

D. Eyre, M. Harkey, MaryAnn Weis, 2007, Bone.

Fine powdering exposes the mineral-protected collagen of bone to protease digestion

D. Eyre, Jiann-Jiu Wu, 1988, Calcified Tissue International.

Assembly of collagen types II, IX and XI into nascent hetero-fibrils by a rat chondrocyte cell line.

D. Eyre, T. Schmid, R. J. Fernandes, 2003, European journal of biochemistry.

Incorporation of structurally defective type II collagen into cartilage matrix in kniest chondrodysplasia.

D. Rimoin, D. Eyre, W. Wilcox, 1998, Archives of biochemistry and biophysics.

Long‐term study of the biochemistry and biomechanics of anterior cruciate ligament‐patellar tendon autografts in goats

D. Eyre, G. Ng, B. Oakes, 1996, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Expression, in cartilage, of a 7-amino-acid deletion in type II collagen from two unrelated individuals with Kniest dysplasia.

D. Rimoin, D. Eyre, W. Wilcox, 1994, American journal of human genetics.

Post‐translational control of collagen fibrillogenesis in mineralizing cultures of chick osteoblasts

W. Landis, D. Eyre, L. Gerstenfeld, 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Collagen in the ageing human intervertebral disc: an increase in covalently bound fluorophores and chromophores.

D. Eyre, S. Hormel, 1991, Biochimica et biophysica acta.

Collagen cross-linking: distribution of hydroxypyridinium cross-links among invertebrate phyla and tissues.

T. Koob, D. Eyre, K. V. Van Ness, 1988, Comparative biochemistry and physiology. B, Comparative biochemistry.

Studies on the Distribution of Hydroxypyridinium Cross‐Links in Different Collagen Types

D. Eyre, Jiann-Jiu Wu, 1985 .

Cartilage type IX collagen is cross-linked by hydroxypyridinium residues.

D. Eyre, J. Wu, J. J. Wu, 1984, Biochemical and biophysical research communications.

Mature bovine Descemet's membrane contains desmosine and isodesmosine.

D. Eyre, J. Heathcote, J. Gross, 1982, Biochemical and biophysical research communications.

Vitreous structure. VI. Age-related changes in the thermal stability and crosslinks of vitreous, articular cartilage and tendon collagens.

D. Eyre, D. Swann, J. M. Snowden, 1982, Biochimica et biophysica acta.

Mature crosslink formation and molecular packing in articular cartilage collagen

D. Eyre, M. Grynpas, F. Shapiro, 1981 .

Biosynthesis of collagen and other matrix proteins by articular cartilage in experimental osteoarthrosis.

D. Eyre, H. Muir, C. McDevitt, 1980, The Biochemical journal.

Bone resorption assessed by immunoassay of urinary cross‐linked collagen peptides in patients with osteogenesis imperfecta

D. Eyre, R. Brenner, A. Bollen, 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Molecular properties and fibril ultrastructure of types II and XI collagens in cartilage of mice expressing exclusively the α1(IIA) collagen isoform.

D. Eyre, L. Wirthlin, A. McAlinden, 2014, Matrix biology : journal of the International Society for Matrix Biology.

Editorial : new biomarkers of bone resorption

D. Eyre, 1992 .

Localized chondro-ossification underlies joint dysfunction and motor deficits in the Fkbp10 mouse model of osteogenesis imperfecta

B. Dawson, R. Schweitzer, Brendan H. Lee, 2021, Proceedings of the National Academy of Sciences.

Short-term calcium supplementation has no effect on biochemical markers of bone remodeling in early postmenopausal women

D. Eyre, M. Soules, C. Chesnut, 2004, Archives of Gynecology and Obstetrics.

Non-Lethal Type VIII Osteogenesis Imperfecta Has Elevated Bone Matrix Mineralization.

F. Glorieux, T. Hefferan, Peter A. Smith, 2016, The Journal of clinical endocrinology and metabolism.

Molecular Consequences of the SERPINH1/HSP47 Mutation in the Dachshund Natural Model of Osteogenesis Imperfecta*

D. Eyre, T. Leeb, F. Seeliger, 2015, The Journal of Biological Chemistry.

The cartilage collagens and joint degeneration.

D. Eyre, M. Weis, J. Wu, 1991, British journal of rheumatology.

Induction of osteoarthrosis in the rabbit knee joint: biochemical studies on the articular cartilage.

M. Glimcher, D. Eyre, Y. Floman, 1980, Clinical orthopaedics and related research.

Fibroblast growth factor-18 is a trophic factor for mature chondrocytes and their progenitors.

D. Thompson, D. Eyre, T. Bukowski, 2002, Osteoarthritis and cartilage.

Influence of plasma calcium and vitamin D on bone collagen. Effects on lysine hydroxylation and crosslink formation.

D. Eyre, I. Dickson, E. Kodicek, 1979, Biochimica et biophysica acta.

MBTPS2 mutations cause defective regulated intramembrane proteolysis in X-linked osteogenesis imperfecta

D. Eyre, I. Kennerknecht, A. Janecke, 2016, Nature Communications.

Collagen cross-links as markers of bone and cartilage degradation

D. Eyre, Jiann-Jiu Wu, L. Atley, 2002 .

Collagen crosslinked N‐telopeptides as markers for evaluating particulate osteolysis: A preliminary study

D. Zukor, D. Eyre, J. Antoniou, 2000, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Degradation of cartilage collagens type II, IX, X and XI by enzymes derived from human articular chondrocytes.

D. Woolley, D. Eyre, T. Schmid, 1990, Matrix.

Human-mouse interspecies collagen I heterotrimer is functional during embryonic development of Mov13 mutant mouse embryos

A. Schnieke, A. Sharpe, A. Berns, 1990, Molecular and cellular biology.

Biochemical studies on repair cartilage resurfacing experimental defects in the rabbit knee.

M. Glimcher, D. Eyre, T. Furukawa, 1980, The Journal of bone and joint surgery. American volume.

Predominance of type I collagen at the surface of avian articular cartilage

M. Glimcher, D. Eyre, D. Brickley-Parsons, 1978, FEBS letters.

The distribution of different molecular species of collagen in fibrous, elastic and hyaline cartilages of the pig.

D. Eyre, H. Muir, H. Muir, 1975, Biochemical Journal.

Evidence for intramolecular crosslinks in chicken bone collagen: the isolation of peptides containing allysine aldol.

M. Glimcher, D. Eyre, 1973, Biochimica et biophysica acta.

A single amino acid substitution (G103D) in the type II collagen triple helix produces Kniest dysplasia.

D. Rimoin, D. Eyre, D. Wilkin, 1994, Human molecular genetics.

Abnormal Bone Collagen Cross‐Linking in Osteogenesis Imperfecta/Bruck Syndrome Caused by Compound Heterozygous PLOD2 Mutations

P. Byers, D. Eyre, U. Schwarze, 2021, JBMR plus.

Kuskokwim Syndrome, a Recessive Congenital Contracture Disorder, Extends the Phenotype of FKBP10 Mutations

S. Bale, M. Gambello, D. Eyre, 2013, Human mutation.

Increase in degraded collagen type II in synovial fluid early in the rabbit meniscectomy model of osteoarthritis.

T. Aigner, D. Eyre, L. Wachsmuth, 2005, Osteoarthritis and cartilage.

Comparative biochemistry of collagen crosslinks: reducible bonds in invertebrate collagens.

M. Glimcher, D. Eyre, 1971, Biochimica et biophysica acta.

Clinical — molecular correlations in the skeletal dysplasias

D. Rimoin, D. Eyre, D. Cohn, 2005, Pediatric Radiology.

Collagen XI chain misassembly in cartilage of the chondrodysplasia (cho) mouse.

D. Eyre, MaryAnn Weis, Melissa A Scott, 2007, Matrix biology : journal of the International Society for Matrix Biology.

Using biochemical markers of bone turnover in clinical practice.

D. Eyre, F. Singer, David R Eyre, 2008, Cleveland Clinic journal of medicine.

The release of crosslinked peptides from type II collagen into human synovial fluid is increased soon after joint injury and in osteoarthritis.

D. Eyre, L. Lohmander, David R Eyre, 2003, Arthritis and rheumatism.

Cartilage markers and their association with cartilage loss on magnetic resonance imaging in knee osteoarthritis: the Boston Osteoarthritis Knee Study

Ali Guermazi, David T Felson, David Eyre, 2007, Arthritis research & therapy.

Urinary levels of type II collagen C-telopeptide crosslink are unrelated to joint space narrowing in patients with knee osteoarthritis

K. Brandt, S. Mazzuca, D. Eyre, 2005, Annals of the rheumatic diseases.

Soft-tissue aging and musculoskeletal function.

S L Woo, J A Buckwalter, J. Buckwalter, 1993, The Journal of bone and joint surgery. American volume.

The collagens of articular cartilage.

D. Eyre, 1991, Seminars in arthritis and rheumatism.

Collagen type IX: Evidence for covalent linkages to type II collagen in cartilage

D. Eyre, K. Walsh, Jiann-Jiu Wu, 1987, FEBS letters.

Early changes in material properties of rabbit articular cartilage after meniscectomy

T. Koob, D. Eyre, A. Grodzinsky, 1983, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Types I and II collagens in intervertebral disc. Interchanging radial distributions in annulus fibrosus.

D. Eyre, H. Muir, H Muir, 1976, The Biochemical journal.

Targeting the LRP5 Pathway Improves Bone Properties in a Mouse Model of Osteogenesis Imperfecta

David Zurakowski, David Eyre, Ugur M Ayturk, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Histological appearance and chemical composition of enamel proteins from mature human molars.

D. Eyre, S. Weidmann, J. Weatherell, 1968, Caries research.

Analyses of lysine aldehyde cross-linking in collagen reveal that the mature cross-link histidinohydroxylysinonorleucine is an artifact

D. Eyre, M. Weis, J. Rai, 2019, The Journal of Biological Chemistry.

Procollagen II Amino Propeptide Processing by ADAMTS-3

D. Eyre, A. Colige, D. Cohn, 2001, The Journal of Biological Chemistry.

HIF-1α metabolically controls collagen synthesis and modification in chondrocytes

P. Carmeliet, D. Eyre, G. Carmeliet, 2019, Nature.

Role of type X collagen on experimental mineralization of eggshell membranes.

D. Eyre, J. Arias, M. S. Fernández, 1997, Connective tissue research.

Advances in collagen cross-link analysis.

D. Eyre, David R Eyre, Mary Ann Weis, 2008, Methods.

Collagen cross-linking in human bone and articular cartilage. Age-related changes in the content of mature hydroxypyridinium residues.

D. Eyre, K. V. Van Ness, I. Dickson, 1988, The Biochemical journal.

Congenital Scoliosis: A Histopathologic Study

D. Eyre, F. Shapiro, 1981, Spine.

Analysis of a crosslinked peptide from calf bone collagen: evidence that hydroxylysyl glycoside participates in the crosslink.

M. Glimcher, D. Eyre, 1973, Biochemical and biophysical research communications.

Structural characteristics of cross-linking sites in type V collagen of bone. Chain specificities and heterotypic links to type I collagen.

D. Eyre, C. Niyibizi, 1994, European journal of biochemistry.

Collagens and cartilage matrix homeostasis.

D. Eyre, David R Eyre, 2004, Clinical orthopaedics and related research.

Collagen XI Collagen IICollagen IX Collagen IX / II Cross-linking Interactions : working model

D. Eyre, 2001 .

Biochemistry of the intervertebral disc.

D. Eyre, D R Eyre, 1979, International review of connective tissue research.

Reducible crosslinks in hydroxylysine-deficient collagens of a heritable disorder of connective tissue.

M. Glimcher, D. Eyre, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Collagen prolyl 3-hydroxylation: a major role for a minor post-translational modification?

D. Eyre, David M. Hudson, D. Hudson, 2013, Connective tissue research.

Sites of stromelysin cleavage in collagen types II, IX, X, and XI of cartilage.

D. Eyre, L. Chun, M. Lark, 1991, The Journal of biological chemistry.

Structurally Abnormal Type II Collagen in a Severe Form of Kniest Dysplasia Caused by an Exon 24 Skipping Mutation*

D. Rimoin, D. Eyre, W. Wilcox, 1998, The Journal of Biological Chemistry.

An amino acid substitution (Gly853-->Glu) in the collagen alpha 1(II) chain produces hypochondrogenesis.

D. Rimoin, D. Eyre, H. Gruber, 1992, Journal of Biological Chemistry.

An RNA-splicing mutation (G+5IVS20) in the type II collagen gene (COL2A1) in a family with spondyloepiphyseal dysplasia congenita.

D. Rimoin, D. Eyre, H. Gruber, 1995, American journal of human genetics.

disorder correlation in patients with a lethal type II collagen mutations with analysis of genotype-phenotype COL 2 A 1 Report of five novel and one recurrent

D. Eyre, A. Paepe, L. Nuytinck, 1999 .

XBP1s-Mediated Endoplasmic Reticulum Proteostasis Network Enhancement Can Selectively Improve Folding and Secretion of an Osteogenesis Imperfecta-Causing Collagen-I Variant

Vincent L. Butty, D. Eyre, M. Shoulders, 2021, bioRxiv.

Rough Endoplasmic Reticulum Abnormalities in a Patient with Spondyloepimetaphyseal Dysplasia with Scoliosis, Joint Laxity, and Finger Deformities

D. Eyre, F. Shapiro, M. Weis, 2006, Ultrastructural pathology.

Molecular properties of matrilin-3 isolated from human growth cartilage.

J. Yates, D. Eyre, G. Kleemann, 2001, Archives of biochemistry and biophysics.

Two-dimensional peptide mapping of cross-linked type IX collagen in human cartilage.

D. Eyre, J. Wu, S. Ichimura, 2000, Archives of biochemistry and biophysics.

COPB2 haploinsufficiency causes a coatopathy with osteoporosis and developmental delay

David R. Murdock, Lisa T. Emrick, Alyssa A. Tran, 2020, bioRxiv.

Abnormal Type I Collagen Post-translational Modification and Crosslinking in a Cyclophilin B KO Mouse Model of Recessive Osteogenesis Imperfecta

K. Tomer, M. Yamauchi, D. Eyre, 2014, PLoS genetics.

Gain-of-function mutation of microRNA-140 in human skeletal dysplasia

Hiroshi I. Suzuki, P. Sharp, A. Nordgren, 2019, Nature Medicine.

Gain-of-function mutation of microRNA-140 in human skeletal dysplasia

Hiroshi I. Suzuki, P. Sharp, A. Nordgren, 2019, Nature Medicine.

A heterozygous collagen defect in a variant of the Ehlers-Danlos syndrome type VII. Evidence for a deleted amino-telopeptide domain in the pro-alpha 2(I) chain.

J. Aldridge, D. Eyre, F. Shapiro, 1985, The Journal of biological chemistry.

Urinary pyridinoline cross-links in Ehlers-Danlos syndrome type VI.

D. Eyre, B. Steinmann, P. Shao, 1995, American journal of human genetics.

The cartilage collagens: structural and metabolic studies.

D. Eyre, J. Wu, P. E. Woods, 1991, The Journal of rheumatology. Supplement.

HIF-1α metabolically controls collagen synthesis and modification in chondrocytes

P. Carmeliet, D. Eyre, G. Carmeliet, 2019, Nature.

Collagen structure and cartilage matrix integrity.

D. Eyre, D R Eyre, J J Wu, 1995, The Journal of rheumatology. Supplement.

Susceptibility of cartilage collagens type II, IX, X, and XI to human synovial collagenase and neutrophil elastase.

D. Woolley, D. Eyre, V. Duance, 1988, European journal of biochemistry.

Rabbit medial collateral ligament scar weakness is associated with decreased collagen pyridinoline crosslink density

C. Frank, D. Eyre, D. McDonald, 1995, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Tendon and motor phenotypes in the Crtap-/- mouse model of recessive osteogenesis imperfecta

Nele A. Haelterman, C. Ambrose, Brendan H. Lee, 2020, bioRxiv.

Glycation of type I collagen selectively targets the same helical domain lysine sites as lysyl oxidase–mediated cross-linking

David R. Eyre, D. Eyre, David M. Hudson, 2018, The Journal of Biological Chemistry.

Premenopausal Ovariectomy‐Related Bone Loss: A Randomized, Double‐Blind, One‐Year Trial of Conjugated Estrogen or Medroxyprogesterone Acetate

J. Wark, D. Eyre, P. Ebeling, 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Quantitative analysis of types I and II collagens in human intervertebral discs at various ages.

D. Eyre, H. Muir, H Muir, 1977, Biochimica et biophysica acta.

An automated method for continuous-flow analysis of radioactivity applicable to the study of collagen crosslinks.

D. Eyre, 1973, Analytical Biochemistry.

The dissolution of bovine and chicken bone collagens in concentrated formic acid

D. Eyre, J. Glimcher, 2005, Calcified Tissue Research.

Structural analysis of the extension peptides on matrix forms of type V collagen in fetal calf bone and skin.

D. Eyre, C. Niyibizi, 1993, Biochimica et biophysica acta.

The carboxypropeptide trimer of type II collagen is a prominent component of immature cartilages and intervertebral-disc tissue.

D. Eyre, C. Niyibizi, J. Wu, 1987, Biochimica et biophysica acta.

COL1A1 C-propeptide mutations cause ER mislocalization of procollagen and impair C-terminal procollagen processing.

D. Eyre, S. Leikin, A. Ashok, 2019, Biochimica et biophysica acta. Molecular basis of disease.

Nonexpression of cartilage type II collagen in a case of Langer-Saldino achondrogenesis.

G. Vawter, D. Eyre, M. Upton, 1986, American journal of human genetics.

Modulation of the secretory pathway rescues zebrafish polycystic kidney disease pathology.

D. Eyre, I. Drummond, S. Le corre, 2014, Journal of the American Society of Nephrology : JASN.

The association of lumbar spondylolisthesis with collagen IX tryptophan alleles.

S. Mirza, J. Chapman, D. Eyre, 2004, The Journal of bone and joint surgery. British volume.

828 ABNORMAL CARTILAGE COLLAGENS IN ACHONDROGENESIS II

D. Eyre, W. Horton, M. A. Machado, 1985, Pediatric Research.

All three chains of 1α2α3α collagen from hyaline cartilage resist human collagenase

D. Woolley, D. Eyre, Jiann-Jiu Wu, 1984 .

Lysyl Oxidase Activity Is Required for Ordered Collagen Fibrillogenesis by Tendon Cells*

M. Kjaer, S. Magnusson, K. Kadler, 2015, The Journal of Biological Chemistry.

Autoreactivity against matrilin-1 in a patient with relapsing polychondritis.

D. Eyre, J. Buckner, Jiann-Jiu Wu, 2000, Arthritis and rheumatism.

Incomplete processing of type II procollagen by a rat chondrosarcoma cell line.

D. Eyre, T. Schmid, M. Harkey, 1997, European journal of biochemistry.

COL11A2 Collagen Gene Transcription Is Differentially Regulated by EWS/ERG Sarcoma Fusion Protein and Wild-type ERG*

H. Yoshikawa, D. Eyre, A. Myoui, 2003, The Journal of Biological Chemistry.

Structural Analysis of Cross-linking Domains in Cartilage Type XI Collagen

D. Eyre, Jiann-Jiu Wu, 1995, The Journal of Biological Chemistry.

Intervertebral Disc Collagen

D. Eyre, Jiann-Jiu Wu, 2003, Journal of Biological Chemistry.

Covalent interactions of type IX collagen in cartilage.

D. Eyre, J. Wu, J. J. Wu, 1989, Connective tissue research.

A growing family of collagens in articular cartilage: identification of 5 genetically distinct types.

D. Eyre, J. Wu, S. Apone, 1987, The Journal of rheumatology.

Collagen cross-linking. Isolation of cross-linked peptides from collagen of chicken bone.

M. Glimcher, D. Eyre, 1973, The Biochemical journal.

Sc65 Is a Novel Endoplasmic Reticulum Protein That Regulates Bone Mass Homeostasis

L. Suva, Frances L. Swain, D. Eyre, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Consensus summary on the diagnosis and treatment of osteoporosis.

G. Andersson, J. Weinstein, E. Myers, 1997, Spine.

Quantitation of hyaluronic acid in tissues by ion-pair reverse-phase high-performance liquid chromatography of oligosaccharide cleavage products.

T. Koob, D. Eyre, L. Chun, 1988, Analytical biochemistry.

CRTAP Is Required for Prolyl 3- Hydroxylation and Mutations Cause Recessive Osteogenesis Imperfecta

F. Glorieux, P. Byers, Brendan H. Lee, 2006, Cell.

A repeated triple lysine motif anchors complexes containing bone sialoprotein and the type XI collagen A1 chain involved in bone mineralization

D. Eyre, J. Oxford, A. Keightley, 2021, The Journal of biological chemistry.

Fkbp10 Deletion in Osteoblasts Leads to Qualitative Defects in Bone

C. Ambrose, P. Fratzl, Brendan H. Lee, 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A Chaperone Complex Formed by HSP47, FKBP65, and BiP Modulates Telopeptide Lysyl Hydroxylation of Type I Procollagen

Brendan H. Lee, D. Eyre, D. Krakow, 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Collagen polymorphism: Two molecular species in pig intervertebral disc

D. Eyre, H. Muir, Helen Muir, 1974, FEBS letters.

Structural and functional characterization of a splicing mutation in the pro-alpha 2(I) collagen gene of an Ehlers-Danlos type VII patient.

D. Weil, D. Eyre, M. D’Alessio, 1990, The Journal of biological chemistry.

Incorporation of type I collagen molecules that contain a mutant alpha 2(I) chain (Gly580-->Asp) into bone matrix in a lethal case of osteogenesis imperfecta.

P. Byers, D. Eyre, J. Bonadio, 1992, The Journal of biological chemistry.

A mutation in the alpha 3 chain of type IX collagen causes autosomal dominant multiple epiphyseal dysplasia with mild myopathy.

L. Kunkel, C. Bönnemann, D. Anthony, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Asporin-deficient mice have tougher skin and altered skin glycosaminoglycan content and structure

M. Warman, D. Eyre, S. Kalamajski, 2017, PloS one.

Increased C-telopeptide Cross-linking of Tendon Type I Collagen in Fibromodulin-deficient Mice*

D. Eyre, A. Oldberg, Cuiping Liu, 2014, The Journal of Biological Chemistry.

Sublingual testosterone replacement improves muscle mass and strength, decreases bone resorption, and increases bone formation markers in hypogonadal men--a clinical research center study.

A. Iranmanesh, T. Barstow, D. Eyre, 1996, The Journal of clinical endocrinology and metabolism.

Mmp14-controlled extracellular matrix homeostasis is required for circadian rhythm

K. Kadler, D. Eyre, Y. Itoh, 2022 .

Molecular Site Specificity of Pyridinoline and Pyrrole Cross-links in Type I Collagen of Human Bone*

D. Eyre, D. Hanson, Dennis A. Hanson, 1996, The Journal of Biological Chemistry.

Application of Biomarkers in the Development of Drugs Intended for the Treatment of Osteoarthritis OARSI FDA Osteoarthritis Biomarkers Working Group

A R Poole, D Heinegård, R. Moskowitz, 2011 .

The cartilage collagens

D. Eyre, Jiann-Jiu Wu, P. E. Woods, 1991 .

The distribution of crosslinking aldehydes in 1 and 2 chains of chicken bone collagen.

M. Glimcher, D. Eyre, 1972, Biochimica et biophysica acta.

Collagen crosslinks in human dentin: Increasing content of hydroxypyridinium residues with age

D. Eyre, Clifford Walters, Dr. David R. Eyre, 1983, Calcified Tissue International.

Distinct post‐translational features of type I collagen are conserved in mouse and human periodontal ligament

D. Eyre, David M. Hudson, D. Dixon, 2017, Journal of periodontal research.

Biochemical aspects of development and ageing of human lumbar intervertebral discs.

D. Eyre, H. Muir, H Muir, 1977, Rheumatology and rehabilitation.

Acetabular augmentation at six- to 30-year follow-up. A biochemical and histological analysis.

D. Eyre, J. Clark, M. Diab, 2005, The Journal of bone and joint surgery. British volume.

Biochemical Markers as Surrogate End Points of Joint Disease

D. Eyre, L. Lohmander, David R. Eyre, 2008 .

Evidence for a previously undetected sequence at the carboxyterminus of the 1 chain of chicken bone collagen.

M. Glimcher, D. Eyre, 1972, Biochemical and biophysical research communications.

CORRELATIONS BETWEEN THE INTRINSIC MECHANICAL PROPERTIES OF HUMAN ARTICULAR CARTILAGE AND ITS COMPOSITION.

V. Mow, C. Armstrong, D. Eyre, 1981 .

BAPN dose dependence of mature crosslinking in bone matrix collagen of rabbit compact bone: corresponding variation of sonic velocity and equatorial diffraction spacing.

S. Lees, D. Eyre, S. Barnard, 1990, Connective tissue research.

Collagen crosslinks and mineral crystallinity in bone of patients with osteogenesis imperfecta

D. Eyre, E. Eanes, M. Weis, 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The predictive role of bone turnover markers for BMD in middle-aged men

M. Battié, T. Videman, D. Eyre, 2006, The aging male : the official journal of the International Society for the Study of the Aging Male.

Biochemical markers of bone metabolism

D. Eyre, 1995 .

Type IX Collagen Neo-Deposition in Degenerative Discs of Surgical Patients Whether Genotyped Plus or Minus for COL9 Risk Alleles

S. Mirza, D. Eyre, Jiann-Jiu Wu, 2011, Spine.

Matrix deposition of tryptophan-containing allelic variants of type IX collagen in developing human cartilage.

D. Eyre, T. Pietka, Jiann-Jiu Wu, 2003, Matrix biology : journal of the International Society for Matrix Biology.

Genetic and Constitutional Influences on Bone Turnover Markers: A Study of Male Twin Pairs

J. Kaprio, T. Videman, M. Battié, 2007, Calcified Tissue International.

Mmp14 is required for matrisome homeostasis and circadian rhythm in fibroblasts

K. Kadler, D. Eyre, Y. Itoh, 2023, bioRxiv.

Anthropometrics and biochemical markers in men.

M. Battié, T. Videman, D. Eyre, 2005, Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry.

XBP1s-Mediated ER Proteostasis Network Enhancement Can Selectively Improve the Folding and Secretion of an Osteogenesis Imperfecta-Causing Collagen-I Variant

Vincent L. Butty, D. Eyre, M. Shoulders, 2023, bioRxiv.

Oro-dental and cranio-facial characteristics of osteogenesis imperfecta type V.

F. Glorieux, Mahim Jain, V. Sutton, 2019, European journal of medical genetics.

Dental and facial characteristics of osteogenesis imperfecta type V

F. Glorieux, Mahim Jain, V. Sutton, 2018, bioRxiv.

Type III collagen: A major constituent of rheumatoid and normal human synovial membrane.

D. Eyre, H. Muir, 1975, Connective tissue research.

Bone Collagen: New Clues to Its Mineralization Mechanism from Recessive Osteogenesis Imperfecta

D. Eyre, M. Weis, 2013, Calcified Tissue International.

Bone Collagen: New Clues to Its Mineralization Mechanism from Recessive Osteogenesis Imperfecta

D. Eyre, M. Weis, 2013, Calcified Tissue International.

Growth characteristics in individuals with osteogenesis imperfecta in North America: results from a multicenter study

J. Krischer, F. Glorieux, P. Byers, 2018, Genetics in Medicine.

HSP47 and FKBP65 cooperate in the synthesis of type I procollagen.

Sulin Wu, D. Eyre, D. Krakow, 2015, Human molecular genetics.

Bone type V collagen: chain composition and location of a trypsin cleavage site.

D. Eyre, C. Niyibizi, 1989, Connective tissue research.

Substitution of cysteine for glycine within the carboxyl-terminal telopeptide of the alpha 1 chain of type I collagen produces mild osteogenesis imperfecta.

P. Byers, D. Eyre, H. Charbonneau, 1988, The Journal of biological chemistry.

Mutations That Alter the Carboxy‐Terminal‐Propeptide Cleavage Site of the Chains of Type I Procollagen Are Associated With a Unique Osteogenesis Imperfecta Phenotype

P. Byers, E. Duncan, M. Szybowska, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The α2 chain of type IX collagen is essential for type IX collagen biosynthesis

D. Eyre, D. Krakow, D. Cohn, 2019, American journal of medical genetics. Part A.

Biochemical markers of bone turnover in lactating and nonlactating postpartum women.

M. Sowers, M. Sowers, D. Eyre, 1995, The Journal of clinical endocrinology and metabolism.

Collagen polymorphism in extracellular matrix of human osteosarcoma.

D. Eyre, F. Shapiro, 1982, Journal of the National Cancer Institute.

Evidence for enhanced collagen type III deposition focally in the territorial matrix of osteoarthritic hip articular cartilage.

D. Eyre, L. Dahlberg, M. Weis, 2016, Osteoarthritis and cartilage.

A multicenter trial of low dose gallium nitrate in patients with advanced Paget's disease of bone.

E. Siris, D. Eyre, B. Bosco, 1995, The Journal of clinical endocrinology and metabolism.

Fibronectin Lacking the ED-B Domain Is a Major Structural Component of Tracheal Cartilage*

D. Eyre, D. Stechschulte, Jiann-Jiu Wu, 1997, The Journal of Biological Chemistry.

Effects of methylprednisolone on collagen biosynthesis in healing acute myocardial infarction.

R. Kloner, F. Schoen, D. Eyre, 1987, The American journal of cardiology.

Characterisation of the major CNBr-Derived peptides of porcine type II collagen.

D. Eyre, H. Muir, 1975, Connective tissue research.

Severe osteogenesis imperfecta caused by a small in‐frame deletion in CRTAP

F. Glorieux, P. Roughley, D. Eyre, 2011, American journal of medical genetics. Part A.

Pediatric Outcomes Data Collection Instrument is a Useful Patient-Reported Outcome Measure for Physical Function in Children with Osteogenesis Imperfecta

J. Krischer, F. Glorieux, Mahim Jain, 2019, Genetics in Medicine.

Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation

L. Suva, Frances L. Swain, A. Tackett, 2016, PLoS genetics.

EFFECT OF PROLONGED WALKING ON CONCRETE ON THE JOINTS OF SHEEP

Robert M. Rose, Eric L. Radin, Igor L. Paul, 1980 .

Covalent Cross-linking of the NC1 Domain of Collagen Type IX to Collagen Type II in Cartilage*

D. Eyre, David R Eyre, Terri Pietka, 2004, Journal of Biological Chemistry.

Hindlimb Skeletal Muscle Function and Skeletal Quality and Strength in +/G610C Mice With and Without Weight‐Bearing Exercise

D. Eyre, D. Salamango, Yong Wang, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The Lability of Aldimine Crosslinks on Dissolution of Chicken Bone Collagen by Protein Denaturants

M. Glimcher, D. Eyre, 1975 .

Amino acid composition of enamel protein in the fully developed human tooth.

D. Eyre, S. Weidmann, 1967, Caries research.

The elastin-like protein matrix of lamprey branchial cartilage is cross-linked by lysyl pyridinoline.

D. Eyre, R. J. Fernandes, 1999, Biochemical and biophysical research communications.

From biomarker to surrogate outcome to osteoarthritis--what are the challenges?

D. Eyre, L. S. Lohmander, 2005, Journal of Rheumatology.

Kuskokwim Syndrome, a Recessive Congenital Contracture Disorder, Extends the Phenotype of FKBP10 Mutations

S. Bale, M. Gambello, D. Eyre, 2013, Human mutation.

Murine tendon function is adversely affected by aggrecan accumulation due to the knockout of ADAMTS5

J. Galante, D. Eyre, J. Sandy, 2012, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Concepts in collagen biochemistry: evidence that collagenopathies underlie osteogenesis imperfecta.

D. Eyre, 1981, Clinical orthopaedics and related research.

Functional geometry of ciliated tentacular arrays in active suspension feeders

Eyre, A. Fogelson, D. Grünbaum, 1998, The Journal of experimental biology.

Corrigendum: Prolyl 3-hydroxylase 1 deficiency causes a recessive metabolic bone disorder resembling lethal/severe osteogenesis imperfecta

C. Tifft, Peter A. Smith, D. Eyre, 2008, Nature Genetics.

Targeting the LRP5 Pathway Improves Bone Properties in a Mouse Model of Osteogenesis Imperfecta

A. Robling, D. Zurakowski, M. Warman, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Molecular alterations due to Col5a1 Haploinsufficiency in a mouse model of classic Ehlers Danlos syndrome.

Brendan H. Lee, D. Eyre, D. Keene, 2021, Human molecular genetics.