N. Chim

发表

The TB Structural Genomics Consortium: a decade of progress.

D. Eisenberg, M. James, J. Sacchettini, 2011, Tuberculosis.

Engineering polymerases for applications in synthetic biology

N. Chim, J. Chaput, Ali Nikoomanzar, 2020, Quarterly Reviews of Biophysics.

Salmonella Mitigates Oxidative Stress and Thrives in the Inflamed Gut by Evading Calprotectin-Mediated Manganese Sequestration.

Eric P. Skaar, R. Edwards, W. Chazin, 2016, Cell host & microbe.

Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface.

J. Feigon, Chin-Ju Park, N. Chim, 2011, Journal of molecular biology.

An extracellular disulfide bond forming protein (DsbF) from Mycobacterium tuberculosis: structural, biochemical, and gene expression analysis.

Soyeon Im, L. Hung, R. Riley, 2010, Journal of molecular biology.

Insights on how the Mycobacterium tuberculosis heme uptake pathway can be used as a drug target.

N. Chim, C. Goulding, C. Owens, 2013, Future medicinal chemistry.

The Structure and Interactions of Periplasmic Domains of Crucial MmpL Membrane Proteins from Mycobacterium tuberculosis.

Yuqi Liu, N. Chim, C. Goulding, 2015, Chemistry & biology.

Advances in Mycobacterium tuberculosis structural genomics: investigating potential chinks in the armor of a deadly pathogen.

N. Chim, C. Goulding, L. M. McMath, 2009, Infectious disorders drug targets.

Synthesis of 2'-Deoxy-α-l-threofuranosyl Nucleoside Triphosphates.

N. Chim, J. Chaput, Jen-Yu Liao, 2018, The Journal of organic chemistry.

Cross-polarization dynamics in polycrystalline samples

C. Dybowski, N. Chim, R. Taylor, 2007 .

Biochemical, Structural and Molecular Dynamics Analyses of the Potential Virulence Factor RipA from Yersinia pestis

Robert V. Swift, Rommie E. Amaro, Nicholas Chim, 2011, PloS one.

Unusual diheme conformation of the heme-degrading protein from Mycobacterium tuberculosis.

N. Chim, C. Goulding, A. Iniguez, 2010, Journal of molecular biology.

Synthesis and Polymerase Recognition of Threose Nucleic Acid Triphosphates Equipped with Diverse Chemical Functionalities.

N. Chim, J. Chaput, Qingfeng Li, 2021, Journal of the American Chemical Society.

Structures of oligomers of a peptide from β-amyloid.

J. Nowick, Johnny D. Pham, N. Chim, 2013, Journal of the American Chemical Society.

NMR Characterization of Partially Deuterated γ-Glycine

C. Dybowski, N. Chim, R. Taylor, 2006 .

Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway

N. Chim, J. Chaput, L. Jackson, 2018, eLife.

Insights into redox sensing metalloproteins in Mycobacterium tuberculosis.

N. Chim, C. Goulding, Parker M. Johnson, 2014, Journal of inorganic biochemistry.

Transliteration of synthetic genetic enzymes

N. Chim, J. Chaput, Xiaolin Liu, 2021, Nucleic acids research.

Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase

N. Chim, J. Chaput, L. Jackson, 2019, Nucleic acids research.

Structural and functional characterization of human telomerase RNA processing and cajal body localization signals.

Tamás Kiss, Patricia Richard, Nicholas Chim, 2007, Molecular cell.

Structural and biochemical characterization of the essential DsbA-like disulfide bond forming protein from Mycobacterium tuberculosis

N. Chim, C. Goulding, C. Harmston, 2013, BMC Structural Biology.

Heme uptake in bacterial pathogens.

N. Chim, C. Goulding, Alfredo Credali, 2014, Current opinion in chemical biology.

Advances In Mycobacterium Tuberculosis Therapeutics Discovery Utlizing Structural Biology.

N. Chim, C. Goulding, C. Owens, 2012 .

Discovery and characterization of a unique mycobacterial heme acquisition system

Angelina Iniguez, Nicholas Chim, Julian P Whitelegge, 2011, Proceedings of the National Academy of Sciences.

Following replicative DNA synthesis by time-resolved X-ray crystallography

N. Chim, J. Chaput, Kefan Yang, 2021, Nature Communications.

The Mycobacterium tuberculosis Secreted Protein Rv0203 Transfers Heme to Membrane Proteins MmpL3 and MmpL11*

N. Chim, C. Goulding, C. Owens, 2013, The Journal of Biological Chemistry.

Evolution of Functionally Enhanced α-l-Threofuranosyl Nucleic Acid Aptamers.

R. Poplin, N. Chim, I. Grubisic, 2021, ACS synthetic biology.

Structural snapshots along the reaction pathway of Yersinia pestis RipA, a putative butyryl-CoA transferase.

N. Chim, C. Goulding, R. Torres, 2014, Acta crystallographica. Section D, Biological crystallography.

Structural insights into RipC, a putative citrate lyase β subunit from a Yersinia pestis virulence operon.

B. Sankaran, N. Chim, C. Goulding, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural basis for TNA synthesis by an engineered TNA polymerase

N. Chim, J. Chaput, S. Sau, 2017, Nature Communications.

Solution structure of the ubiquitin‐binding domain in Swa2p from Saccharomyces cerevisiae

Walter E. Gall, T. Graham, Jing Xiao, 2004, Proteins: Structure, Function, and Bioinformatics.

Heme uptake in bacterial pathogens.

N. Chim, C. Goulding, Alfredo Credali, 2014, Current opinion in chemical biology.

Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid

P. Herdewijn, N. Chim, J. Chaput, 2022, Nucleic acids research.