I. Ekiel

发表

Preparation and characterization of bacterial protein complexes for structural analysis.

A. Berghuis, Z. Jia, A. Matte, 2009, Advances in protein chemistry and structural biology.

Solution structure of the PDZ2 domain from cytosolic human phosphatase hPTP1E complexed with a peptide reveals contribution of the beta2-beta3 loop to PDZ domain-ligand interactions.

Kalle Gehring, Irena Ekiel, G. Kozlov, 2002, Journal of molecular biology.

Coiled-coil helix rotation selects repressing or activating state of transcriptional regulator DhaR.

R. Shi, I. Ekiel, M. Cygler, 2014, Structure.

NMR studies of malaria. 31P nuclear magnetic resonance of blood from mice infected with Plasmodium berghei.

R. Deslauriers, I. Ekiel, I. Smith, 1982, Biochimica et biophysica acta.

Metastasis-associated Protein S100A4 Induces Angiogenesis through Interaction with Annexin II and Accelerated Plasmin Formation*

I. Ekiel, V. Alakhov, G. Pietrzynski, 2005, Journal of Biological Chemistry.

1H, 13C and 15N resonance assignments of the human phosphatase PRL-3.

G. Kozlov, K. Gehring, I. Ekiel, 2002, Journal of biomolecular NMR.

Hydroxydiether Lipid Structures in Methanosarcina spp. and Methanococcus voltae

I. Ekiel, C. Choquet, G. Patel, 1993, Applied and environmental microbiology.

Structural studies of the major glycolipid from Saccharopolyspora genus.

A. Gamian, B. Szponar, I. Ekiel, 1996, Carbohydrate research.

Tetraether lipids of Methanospirillum hungatei with head groups consisting of phospho-N,N-dimethylaminopentanetetrol, phospho-N,N,N-trimethylaminopentanetetrol, and carbohydrates.

I. Ekiel, G. Sprott, G. Ferrante, 1994, Biochimica et biophysica acta.

A novel core lipid isolated from the aceticlastic methanogen, Methanothrix concilii GP6

I. Ekiel, G. Patel, G. Sprott, 1988 .

Structure of the major polar lipids isolated from the aceticlastic methanogen, Methanothrix concilii GP6

I. Ekiel, G. Patel, G. Sprott, 1988 .

Structures of diether lipids of Methanospirillum hungatei containing novel head groups N,N-diniethylamino- and N,N,N-trimethylaminopentanetetrol

I. Ekiel, G. Sprott, G. Ferrante, 1987 .

Structurally unique interaction of RBD-like and PH domains is crucial for yeast pheromone signaling

T. Sulea, M. Whiteway, J. Baardsnes, 2013, Molecular biology of the cell.

Synthesis, Conformation and Hydrolytic Stability of p1,p3−Dinucleoside Triphosphates Related to mRNA 5′-cap, and Comparative Kinetic Studies on their Nucleoside and Nucleoside Monophosphate Analogs

I. Ekiel, J. Stȩpiński, E. Darżynkiewicz, 1990 .

Chemical synthesis and characterization of 7-methylguanosine cap analogs

A. Shatkin, I. Ekiel, E. Darżynkiewicz, 1985 .

Methyl esterification of m7G5'p reversibly blocks its activity as an analog of eukaryotic mRNA 5'-caps.

M. Morgan, A. Shatkin, I. Ekiel, 1981, Journal of molecular biology.

Structural basis for different inhibitory specificities of human cystatins C and D.

I. Ekiel, M. Abrahamson, F. Kasprzykowski, 1998, Biochemistry.

Binding the atypical RA domain of Ste50p to the unfolded Opy2p cytoplasmic tail is essential for the high-osmolarity glycerol pathway.

T. Sulea, M. Whiteway, I. Ekiel, 2009, Molecular biology of the cell.

β-globin mRNAs capped with m7G, m22.7G or m32.2.7G differ in intrinsic translation efficiency

I. Ekiel, J. Stȩpiński, E. Darżynkiewicz, 1988 .

High‐resolution proton magnetic resonance spectra of morphine and its three O‐acetyl derivatives

I. Ekiel, I. Smith, G. Neville, 1987 .

Mevalonic acid is partially synthesized from amino acids in Halobacterium cutirubrum: a 13C nuclear magnetic resonance study

I. Ekiel, G. Sprott, I. Smith, 1986, Journal of bacteriology.

Acetate and CO2 assimilation by Methanothrix concilii

I. Ekiel, G. Patel, G. Sprott, 1985, Journal of bacteriology.

CHAPTER 15 – Phosphorus-31 NMR of Phospholipids in Membranes

I. Ekiel, I. Smith, 1984 .

A 31P-NMR study of structural and functional aspects of phosphate and phosphonate distribution in Tetrahymena.

R. Deslauriers, H. Jarrell, R. Byrd, 1982, Biochimica et biophysica acta.

Two stable unfolding intermediates of the disease-causing L68Q variant of human cystatin C.

I. Ekiel, B. Gerhartz, M. Abrahamson, 1998, Biochemistry.

Inhibition of eukaryotic translation by nucleoside 5'-monophosphate analogues of mRNA 5'-cap: changes in N7 substituent affect analogue activity.

N. Sonenberg, I. Ekiel, J. Stȩpiński, 1989, Biochemistry.

Inhibition of eukaryotic translation by analogues of messenger RNA 5'-cap: chemical and biological consequences of 5'-phosphate modifications of 7-methylguanosine 5'-monophosphate.

I. Ekiel, E. Darżynkiewicz, S. Tahara, 1987, Biochemistry.

H(C)CH-COSY and (H)CCH-COSY experiments for 13C-labeled proteins in H2O solution.

K. Gehring, I. Ekiel, 1998, Journal of magnetic resonance.

Structure and dynamics of alpha-tocopherol in model membranes and in solution: a broad-line and high-resolution NMR study.

I. Ekiel, I. Smith, K. Ingold, 1988, Biochemistry.

Conformational parameters of the carbohydrate moieties of α-arabinonucleosides

I. Ekiel, E. Darżynkiewicz, D. Shugar, 1981 .

Conformations of d-gluconic, d-mannonic, and d-galactonic acids in solution, as determined by n.m.r. spectroscopy

I. Ekiel, D. Horton, Z. Walaszek, 1983 .

Identification of degradation artifacts formed upon treatment of hydroxydiether lipids from methanogens with methanolic HCl

I. Ekiel, G. Sprott, 1992 .

Calculations of 1H NMR coupling constants for conformational studies of isomeric pentofuranosyl nucleosides

I. Ekiel, A. Jaworski, 1979 .

Solution conformation and relative acidities of the sugar hydroxyls of the O'-methylated derivates of the antimetabolite 9-beta-D-xylofuranosyladenine.

I. Ekiel, E. Darżynkiewicz, D. Shugar, 1978, Biochemistry.

Correlations of conformational parameters and equilibrium conformational states in a variety of beta-D-arabinonucleosides and their analogues.

I. Ekiel, E. Darżynkiewicz, D. Shugar, 1979, Biochimica et biophysica acta.

A Medium-Throughput Structural Proteomics Approach Applied to the Genome of E. coli

Allan Matte, Kalle Gehring, Irena Ekiel, 2009 .

Structure and Conformation of the Antiviral Agent 5-Methoxymethyl-2′-deoxyuridine

L. Delbaere, I. Ekiel, G. Tourigny, 1986 .

Biosynthesis of isoleucine in methanogenic bacteria: a carbon-13 NMR study

I. Ekiel, G. Sprott, I. Smith, 1984 .

Structure of the major glycolipid from Rothia dentocariosa.

A. Gamian, I. Ekiel, M. Paściak, 2002, Biochimica et biophysica acta.

Biosynthetic pathways in Methanospirillum hungatei as determined by 13C nuclear magnetic resonance

I. Ekiel, G. Sprott, I. Smith, 1983, Journal of bacteriology.

Determined by 13C Nuclear Magnetic Resonancet

I. Ekiel, G. Sprott, I. Smith, 2003 .

Metabolic Pathways in Methanococcus jannaschii and Other Methanogenic Bacteria

I. Ekiel, G. Patel, G. Sprott, 1993, Applied and environmental microbiology.

NMR studies of malaria : Glycolysis in red cells of mice infected with plasmodium-berghei and the effects thereon of antimalarial drugs

R. Deslauriers, I. Ekiel, I. Smith, 1983 .

The structure of the O-specific polysaccharide chain from Citrobacter O23-lipopolysaccharide.

I. Ekiel, E. Katzenellenbogen, E. Romanowska, 1988, Carbohydrate research.

The state of the lipids in the purple membrane of Halobacterium cutirubrum as seen by 31P NMR.

M. Kates, I. Ekiel, D. Marsh, 1981, Biochemical and biophysical research communications.

Molecular order and dynamics of diphytanylglycerol phospholipids: a 2H and 31P-NMR study☆

M. Kates, I. Ekiel, I. Smith, 1990 .

NMR structural studies of human cystatin C dimers and monomers.

K. Gehring, I. Ekiel, S. Labelle, 1997, Journal of molecular biology.

Coupling constants between cisoidal protons in pentose nucleosides. Limitations of range of application of Karplus relation, and solution conformations of .beta.-arabinofuranosyl and .beta.-xylofuranosyl nucleosides

I. Ekiel, D. Shugar, A. Jaworski, 1978 .

Conformation and Antiherpes Activity of 3′- and 5′-Azido and Amino Analogs of 5-Methoxymethyl-2′-Deoxyuridine

I. Ekiel, G. Tourigny, Sagar V. Gupta, 1989 .

Relationship between structure and antiviral activity of 5-methoxymethyl-2′-deoxyuridine and 5-methoxymethyl-1-(2′-deoxy-β-d-lyxofuranosyl)uracil

L. Delbaere, E. De Clercq, O. El-Kabbani, 1987 .

Structure and conformation of 5-methoxymethyl-1-(2′-deoxy-β-D-lyxofuranosyl)uracil

L. Delbaere, O. El-Kabbani, J. Quail, 1986 .

13C-n.m.r. analysis of the effects of dissociation of the hydroxyl groups of 1-β-d-arabinofuranosylcytosine and its O’-methyl derivatives on conformation

I. Ekiel, E. Darżynkiewicz, D. Shugar, 1981 .

Conformation in aqueous medium of the neutral, protonated and anionic forms of 9-beta-D-arabinofuranosyladenine.

I. Ekiel, E. Darżynkiewicz, D. Shugar, 1976, Biochimica et biophysica acta.

Proton‐Magnetic‐Resonance Study of the Solution Conformation of the α and β Anomers of 5‐Ethyl‐2′‐deoxyuridine

I. Ekiel, D. Shugar, M. Remin, 1975 .

Solution conformations of the antimetabolite 9-beta-D-xylofuranosyladenine and its 8-bromo analogue.

I. Ekiel, D. Shugar, 1979, Acta Biochimica Polonica.

Structure and conformation of pyrimidine lyxofuranosides. 1-.beta.-D-Lyxofuranosyluracil, 1-.beta.-D-lyxofuranosylcytosine, and some O'-methyl derivatives

I. Ekiel, E. Darżynkiewicz, D. Shugar, 1979 .

A 2H-NMR study of Acholeplasma laidlawii membranes highly enriched in myristic acid.

R. Deslauriers, H. Jarrell, R. Byrd, 1982, Biochimica et biophysica acta.

Structural characterization of the lipids of Methanococcus voltae, including a novel N-acetylglucosamine 1-phosphate diether.

I. Ekiel, G. Sprott, G. Ferrante, 1986, The Journal of biological chemistry.

Production of Specifically Labeled Compounds by Methanobacterium espanolae Grown on H2-CO2 plus [13C]Acetate

I. Ekiel, G. B. Patel, D. Sprott, 1993, Applied and environmental microbiology.

Structure and conformation of 8-bromo-9-.beta.-D-xylofuranosyladenine in the solid state and in solution

I. Ekiel, M. Cygler, D. Shugar, 1982 .

Structure and function of the C-terminal PABC domain of human poly(A)-binding protein

G. Kozlov, K. Gehring, J. Trempe, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Solution structure of a two-repeat fragment of major vault protein.

G. Kozlov, K. Gehring, I. Ekiel, 2005, Journal of molecular biology.

Insights into function of PSI domains from structure of the Met receptor PSI domain.

G. Kozlov, K. Gehring, J. Schrag, 2004, Biochemical and biophysical research communications.

Specific interaction of ERp57 and calnexin determined by NMR spectroscopy and an ER two‐hybrid system

G. Kozlov, K. Gehring, J. Trempe, 2004, The EMBO journal.

Structural proteomics of an archaeon

Mark Gerstein, Yuval Kluger, Kalle Gehring, 2000, Nature Structural Biology.

Structural basis of ligand recognition by PABC, a highly specific peptide‐binding domain found in poly(A)‐binding protein and a HECT ubiquitin ligase

Kalle Gehring, Nahum Sonenberg, Irena Ekiel, 2004, The EMBO journal.

Solution Structure and Internal Motion of a Bioactive Peptide Derived from Nerve Growth Factor*

K. Gehring, I. Ekiel, N. Beglova, 1998, The Journal of Biological Chemistry.

Novel, acid-labile, hydroxydiether lipid cores in methanogenic bacteria.

I. Ekiel, G. Sprott, C. Dicaire, 1990, The Journal of biological chemistry.

Contribution of Structural Genomics to Understanding the Biology of Escherichia coli

Z. Jia, A. Matte, K. Gehring, 2003, Journal of bacteriology.

Structures of minor ether lipids isolated from the aceticlastic methanogen, Methanothrix concilii GP6.

J. Brisson, I. Ekiel, G. Sprott, 1989, Journal of lipid research.

Rapid fold and structure determination of the archaeal translation elongation factor 1β from Methanobacterium thermoautotrophicum

A. Yee, G. Kozlov, K. Gehring, 2000, Journal of biomolecular NMR.

Structural basis of the regulation of the CbpA co-chaperone by its specific modulator CbpM.

M. O’Connor-McCourt, J. Baardsnes, I. Ekiel, 2010, Journal of molecular biology.

Solution Structure of the Orphan PABC Domain fromSaccharomyces cerevisiae Poly(A)-binding Protein*

G. Kozlov, K. Gehring, J. Trempe, 2002, The Journal of Biological Chemistry.

ESI-MS and FTIR studies of the interaction between the second PDZ domain of hPTP1E and target peptides.

I. Ekiel, A. English, R. Papp, 2003, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Structural Insights into Molecular Function of the Metastasis-associated Phosphatase PRL-3*

G. Kozlov, K. Gehring, I. Ekiel, 2004, Journal of Biological Chemistry.

I. Ekiel, M. Abrahamson, 1996, The Journal of Biological Chemistry.

Affinity purification and elimination of methionine oxidation in recombinant human cystatin C.

P. Berti, I. Ekiel, M. Abrahamson, 1997, Protein expression and purification.

The Solution Structure of YbcJ from Escherichia coli Reveals a Recently Discovered αL Motif Involved in RNA Binding

K. Gehring, I. Ekiel, M. Cygler, 2003, Journal of bacteriology.

Amino acid biosynthesis and sodium-dependent transport in Methanococcus voltae, as revealed by 13C NMR.

I. Ekiel, K. Jarrell, G. Sprott, 1985, European journal of biochemistry.

NMR structure of YcgL, a conserved protein from Escherichia coli representing the DUF709 family, with a novel α/β/α sandwich fold

I. Ekiel, M. Cygler, O. Minailiuc, 2007, Proteins.

Letter to the Editor: 1H, 13C and 15N resonance assignments of human 5,10-methenyltetrahydrofolate synthetase

E. H. Copeland, I. Ekiel, M. Cygler, 2004, Journal of biomolecular NMR.

Structure of CbpA J-Domain Bound to the Regulatory Protein CbpM Explains Its Specificity and Suggests Evolutionary Link between CbpM and Transcriptional Regulators

J. Baardsnes, R. Shi, I. Ekiel, 2014, PloS one.

Identification of a functional site on the type I TGF‐β receptor by mutational analysis of its ectodomain

M. O’Connor-McCourt, T. Sulea, A. Guimond, 2002, FEBS letters.

Characterization of the phase behavior of phosphonolipids in model and biological membranes by 31P-NMR

R. Deslauriers, H. Jarrell, R. Byrd, 1981 .

Solution structure of the PDZ2 domain from human phosphatase hPTP1E and its interactions with C-terminal peptides from the Fas receptor.

G. Kozlov, K. Gehring, I. Ekiel, 2000, Biochemistry.

Design and solution structure of functional peptide mimetics of nerve growth factor.

K. Gehring, I. Ekiel, N. Beglova, 2000, Journal of medicinal chemistry.

Effect of peptide binding on amide proton exchange rates in the PDZ2 domain from human phosphatase hPTP1E.

K. Gehring, I. Ekiel, D. Banville, 1998, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Structural Evidence That Brain Cyclic Nucleotide Phosphodiesterase Is a Member of the 2H Phosphodiesterase Superfamily*

P. Gutiérrez, G. Kozlov, K. Gehring, 2003, Journal of Biological Chemistry.

Binding the atypical RA domain of Ste50p to the unfolded Opy2p cytoplasmic tail is essential for the high-osmolarity glycerol pathway.

T. Sulea, M. Whiteway, I. Ekiel, 2009, Molecular biology of the cell.