S. Vasudevan

Wei Liu, Mark J. Schreiber, Swee Hoe Ong, 2008, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

Nano-Sized Albumin-Copolymer Micelles for Efficient Doxorubicin Delivery

Arvind Ramanathan, Tanja Weil, A. Ramanathan, 2012, Biointerphases.

Dihydropteridine reductase from Escherichia coli.

S. Vasudevan, D. Shaw, W. Armarego, 1988, The Biochemical journal.

An inducible heat shock protein 70 small molecule inhibitor demonstrates anti-dengue virus activity, validating Hsp70 as a host antiviral target.

Philip F. Hughes, T. Haystead, S. Vasudevan, 2016, Antiviral research.

Novel dengue virus inhibitor 4-HPR activates ATF4 independent of protein kinase R-like Endoplasmic Reticulum Kinase and elevates levels of eIF2α phosphorylation in virus infected cells.

S. Vasudevan, D. Jans, J. Fraser, 2016, Antiviral research.

Depletion of macrophages in mice results in higher dengue virus titers and highlights the role of macrophages for virus control

K. Fink, S. Vasudevan, W. Schul, 2009, European journal of immunology.

Expression, purification and crystallization of the C-terminal domain of Escherichia coli adenylyltransferase.

D. Ollis, P. Carr, D. Wen, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Sulfated Polysaccharide, Curdlan Sulfate, Efficiently Prevents Entry/Fusion and Restricts Antibody-Dependent Enhancement of Dengue Virus Infection In Vitro: A Possible Candidate for Clinical Application

N. Nomura, A. Ryo, S. Vasudevan, 2013, PLoS neglected tropical diseases.

Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo.

M. Ng, T. Haystead, S. Vasudevan, 2014, Antiviral research.

Experimental evidence for a high rate of maternal-fetal transmission of dengue virus in the presence of antibodies in immunocompromised mice

S. Vasudevan, Satoru Watanabe, K. W. Chan, 2022, EBioMedicine.

Flavivirus RNA transactions from viral entry to genome replication.

M. Garcia-Blanco, C. Nicchitta, S. Vasudevan, 2016, Antiviral research.

Optimizing celgosivir therapy in mouse models of dengue virus infection of serotypes 1 and 2: The search for a window for potential therapeutic efficacy.

S. Vasudevan, E. Ooi, G. Dow, 2016, Antiviral research.

Role of T cells, cytokines and antibody in dengue fever and dengue haemorrhagic fever

S. Vasudevan, Feng Gu, J. Fink, 2006, Reviews in medical virology.

Rational Engineering and Characterization of an mAb that Neutralizes Zika Virus by Targeting a Mutationally Constrained Quaternary Epitope.

Vidya Subramanian, Aditya Raguram, S. Vasudevan, 2018, Cell host & microbe.

A dengue fever viremia model in mice shows reduction in viral replication and suppression of the inflammatory response after treatment with antiviral drugs.

Wei Liu, W. Liu, S. Vasudevan, 2007, The Journal of infectious diseases.

Luteolin restricts dengue virus replication through inhibition of the proprotein convertase furin

Zhongde Zhang, S. Vasudevan, D. Luo, 2017, Antiviral research.

Evaluation of dengue antiviral candidates in vivo in mouse model.

S. Vasudevan, Satoru Watanabe, 2014, Methods in molecular biology.

The Magnitude of Dengue Virus NS1 Protein Secretion Is Strain Dependent and Does Not Correlate with Severe Pathologies in the Mouse Infection Model

S. Vasudevan, C. Ruedl, W. Shuai, 2012, Journal of Virology.

Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial.

J. Connolly, S. Vasudevan, E. Ooi, 2012, Antiviral research.

A Small-Molecule Dengue Virus Entry Inhibitor (cid:1) †

E. Jacoby, S. Vasudevan, W. Schul, 2009 .

Phage Display Approaches for the Isolation of Monoclonal Antibodies Against Dengue Virus Envelope Domain III from Human and Mouse Derived Libraries

Moon Y. F. Tay, S. Vasudevan, M. Y. Tay, 2012, International journal of molecular sciences.

Interferon-mediated ISG15 conjugation restricts dengue virus 2 replication.

K. Shimotohno, S. Vasudevan, Youichi Suzuki, 2014, Biochemical and biophysical research communications.

Secreted dengue virus NS1 is predominantly dimeric and in complex with high-density lipoprotein

S. Vasudevan, E. Ooi, Bing Liang Alvin Chew, 2022, bioRxiv.

Preclinical evaluation of [18F]FDG-PET as a biomarker of lymphoid tissue disease and inflammation in Zika virus infection

A. Chacko, S. Vasudevan, S. Kalimuddin, 2022, European Journal of Nuclear Medicine and Molecular Imaging.

Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance

M. Ng, S. Vasudevan, D. Metcalfe, 2011, Proceedings of the National Academy of Sciences.

Fine-tuning DNA/albumin polyelectrolyte interactions to produce the efficient transfection agent cBSA-147.

H. Luhmann, A. Ramanathan, T. Weil, 2010, Biomaterials.

Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKV nsP4 suppresses eIF2α phosphorylation

M. Ng, S. Vasudevan, A. P. Rathore, 2013, Virology Journal.

The 37-amino-acid interdomain of dengue virus NS5 protein contains a functional NLS and inhibitory CK2 site.

J. Forwood, S. Vasudevan, C. Xiao, 1999, Biochemical and biophysical research communications.

Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers for In Situ Live-Cell Molecular Imaging of Dengue Virus Replication

A. Chacko, S. Vasudevan, Satoru Watanabe, 2020, International journal of molecular sciences.

Identifi cation of Dengue-SpecifiAntibody Fragments Using Phage Display

S. Vasudevan, N. Moreland, Chin Chin Lee, 2014 .

Identification of dengue-specific human antibody fragments using phage display.

Moon Y. F. Tay, S. Vasudevan, M. Y. Tay, 2014, Methods in molecular biology.

Clinical features of dengue

J. Farrar, D. Gubler, S. Vasudevan, 2014 .

Mutations in the cytoplasmic domain of dengue virus NS4A affect virus fitness and interactions with other non-structural proteins.

S. Vasudevan, K. W. Chan, N. G. Brown, 2020, The Journal of general virology.

Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients

Uma S. Kamaraj, P. D. de Sessions, J. Connolly, 2016, PLoS neglected tropical diseases.

Isolation and nucleotide sequence of the hmp gene that encodes a haemoglobin-like protein in Escherichia coli K-12

N. Dixon, S. Vasudevan, R. Poole, 1991, Molecular and General Genetics MGG.

Dengue virus serotype infection specifies the activation of the unfolded protein response

E. Chevet, O. Pluquet, S. Vasudevan, 2007, Virology Journal.

Stearoyl-CoA desaturase-1 is required for flavivirus RNA replication.

S. Tajima, S. Vasudevan, M. Saijo, 2019, Antiviral research.

Optimal flexibility of the linker region of Zika virus NS5 methyltransferase-polymerase is critical for virus replication.

S. Vasudevan, J. Lescar, E. Ooi, 2021, Antiviral research.

Molecular basis for specific viral RNA recognition and 2′-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)

P. Shi, K. Swaminathan, S. Vasudevan, 2015, Proceedings of the National Academy of Sciences.

Nuclear localization of dengue virus (DENV) 1-4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin.

Moon Y. F. Tay, S. Vasudevan, M. Y. Tay, 2013, Antiviral research.

Dengue pathogenesis: viral factors.

J. Farrar, D. Gubler, E. Harris, 2014 .

The Dengue Virus Replication Complex: From RNA Replication to Protein-Protein Interactions to Evasion of Innate Immunity.

S. Vasudevan, J. Lescar, C. Kang, 2018, Advances in experimental medicine and biology.

Viral Entry and NS1 as Potential Antiviral Drug Targets.

F. Rey, R. Hilgenfeld, S. Vasudevan, 2018, Advances in experimental medicine and biology.

Crystallization and preliminary X-ray analysis of Escherichia coli GlnK.

H. Westerhoff, D. Ollis, P. Carr, 1998, Acta Crystallographica Section D: Biological Crystallography.

Dengue vector control: new approaches.

A. James, J. Farrar, D. Gubler, 2014 .

The Escherichia coli signal transducers PII (GlnB) and GlnK form heterotrimers in vivo: fine tuning the nitrogen signal cascade.

H. Westerhoff, D. Ollis, D. Wen, 2000, Proceedings of the National Academy of Sciences of the United States of America.

A genomics approach to understanding host response during dengue infection.

Mark J. Schreiber, J. George, Chia-Lin Wei, 2006, Novartis Foundation symposium.

Finding new medicines for flaviviral targets.

Yen-Liang Chen, A. Sampath, S. Vasudevan, 2006, Novartis Foundation symposium.

Assessing the utility of antivirals for preventing maternal-fetal transmission of zika virus in pregnant mice.

S. Vasudevan, Satoru Watanabe, K. W. Chan, 2019, Antiviral research.

Characterisation of inter- and intra-molecular interactions of the dengue virus RNA dependent RNA polymerase as potential drug targets.

L. Llewellyn, S. Vasudevan, D. Jans, 2001, Farmaco.

Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents.

S. Vasudevan, S. Alonso, S. Sabatini, 2020, European journal of medicinal chemistry.

Clinical and experimental evidence for transplacental vertical transmission of flaviviruses.

S. Vasudevan, Satoru Watanabe, 2022, Antiviral research.

Luteolin escape mutants of dengue virus map to prM and NS2B and reveal viral plasticity during maturation

S. Vasudevan, Wei Zhang, D. Luo, 2018, Antiviral research.

Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase.

S. Vasudevan, S. Sabatini, G. Manfroni, 2020, ACS medicinal chemistry letters.

Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial.

J. Connolly, J. Low, Y. Cheung, 2014, The Lancet. Infectious diseases.

Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model.

J. Connolly, S. Vasudevan, E. Ooi, 2011, Antiviral research.

Sub-genomic RNA from dengue virus type 2 suppresses replication of dengue virus genomes and interacts with virus-encoded NS3 and NS5 proteins.

S. Vasudevan, J. Aaskov, K. B. Naripogu, 2020, ACS infectious diseases.

Antiviral Candidates for Treating Hepatitis E Virus Infection

S. Vasudevan, J. Mackenzie, Daniel Enosi Tuipulotu, 2019, Antimicrobial Agents and Chemotherapy.

Host Gene Expression Profiling of Dengue Virus Infection in Cell Lines and Patients

Joshy George, Vladimir A. Kuznetsov, Mark J. Schreiber, 2007, PLoS neglected tropical diseases.

Flexibility between the Protease and Helicase Domains of the Dengue Virus NS3 Protein Conferred by the Linker Region and Its Functional Implications

S. Vasudevan, J. Lescar, A. Davidson, 2010, The Journal of Biological Chemistry.

Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus

Zheng Yin, Ulrich Hommel, A. D'arcy, 2006, Nature Structural &Molecular Biology.

Decision Tree Algorithms Predict the Diagnosis and Outcome of Dengue Fever in the Early Phase of Illness

Mark J. Schreiber, Cameron P. Simmons, Subhash G. Vasudevan, 2008, PLoS neglected tropical diseases.

A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection.

P. Sexton, S. Vasudevan, D. Jans, 2014, The Journal of infectious diseases.

Construction and characterization of a stable subgenomic dengue virus type 2 replicon system for antiviral compound and siRNA testing.

Yen-Liang Chen, S. Vasudevan, A. Davidson, 2007, Antiviral research.

Dengue virus regulates type I interferon signalling in a strain-dependent manner in human cell lines.

M. Hibberd, S. Vasudevan, K. Tang, 2008, The Journal of general virology.

Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target.

Ting Xu, A. Sampath, S. Vasudevan, 2008, Antiviral research.

Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

Ting Xu, A. Sampath, A. Chao, 2006, Journal of Virology.

Cholesterol biosynthesis modulation regulates dengue viral replication.

M. Labow, S. Vasudevan, Feng Gu, 2009, Virology.

Genomic Epidemiology of a Dengue Virus Epidemic in Urban Singapore

Mark J. Schreiber, E. Holmes, Harold Soh, 2009, Journal of Virology.

The Early Clinical Features of Dengue in Adults: Challenges for Early Clinical Diagnosis

J. Low, Y. Cheung, Y. Leo, 2011, PLoS neglected tropical diseases.

Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase

S. Vasudevan, J. Lescar, A. El Sahili, 2020, Journal of Virology.

Development and characterization of specific anti‐Usutu virus chicken‐derived single chain variable fragment antibodies

K. Stiasny, S. Vasudevan, T. Skern, 2020, Protein science : a publication of the Protein Society.

A systematic approach to the development of a safe live attenuated Zika vaccine

S. Vasudevan, K. Tryggvason, E. Ooi, 2018, Nature Communications.

A review of transmission models of dengue: A quantitative and qualitative analysis of model features

D. Cummings, T. Scott, J. Farrar, 2014 .

18F-Fluorodeoxyglucose Positron Emission Tomography as a window into human dengue pathophysiology.

Tiang Siew Yap, J. Low, J. Totman, 2020, Antiviral research.

A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication

Dahai Luo, Subhash G. Vasudevan, Moon Y. F. Tay, 2015, PLoS pathogens.

Economic and disease burden of dengue.

D. Gubler, E. Undurraga, Y. Halasa, 2014 .

Early Dengue infection and outcome study (EDEN) - study design and preliminary findings.

J. Low, Y. Leo, M. Hibberd, 2006, Annals of the Academy of Medicine, Singapore.

Current Status of Dengue Therapeutics Research and Development

J. Low, S. Vasudevan, E. Ooi, 2017, The Journal of infectious diseases.

Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication

Ching Hua Lee, J. Chu, C. Rice, 2016, PLoS pathogens.

Identification of covalent active site inhibitors of dengue virus protease

S. Vasudevan, S. Gayen, A. Poulsen, 2015, Drug design, development and therapy.

Surveillance and control of urban dengue vectors.

Duane J. Gubler, J. Farrar, D. Gubler, 2014 .

Animal models for studying dengue pathogenesis and therapy.

S. Vasudevan, S. Alonso, Satoru Watanabe, 2015, Antiviral research.

Flavohemoglobin Hmp, but Not Its Individual Domains, Confers Protection from Respiratory Inhibition by Nitric Oxide in Escherichia coli*

S. Vasudevan, R. Poole, G. P. White, 2003, Journal of Biological Chemistry.

Rapid determination of protein stability and ligand binding by differential scanning fluorimetry of GFP-tagged proteins

S. Vasudevan, P. Schaeffer, A. Cooper, 2012 .

The 92-min region of the Escherichia coli chromosome: location and cloning of the ubiA and alr genes.

N. Dixon, S. Vasudevan, N. Stamford, 1993, Gene.

Update on Dengue: Epidemiology, Virus Evolution, Antiviral Drugs, and Vaccine Development

D. Gubler, A. Wilder-Smith, S. Vasudevan, 2010, Current infectious disease reports.

Escherichia coli PII protein: purification, crystallization and oligomeric structure

D. Ollis, N. Dixon, P. Carr, 1994, FEBS letters.

The Interdomain Region of Dengue NS5 Protein That Binds to the Viral Helicase NS3 Contains Independently Functional Importin β1 and Importin α/β-Recognized Nuclear Localization Signals*

S. Vasudevan, D. Jans, M. Johansson, 2002, The Journal of Biological Chemistry.

Dengue and Zika: Control and Antiviral Treatment Strategies

R. Hilgenfeld, S. Vasudevan, 2019, Advances in Experimental Medicine and Biology.

The Interdomain Region of Dengue NS5 Protein Interacts with NS3 and Host Proteins

S. Vasudevan, D. Jans, M. Johansson, 2002 .

A small region of the dengue virus-encoded RNA-dependent RNA polymerase, NS5, confers interaction with both the nuclear transport receptor importin-beta and the viral helicase, NS3.

S. Vasudevan, D. Jans, M. Johansson, 2001, The Journal of general virology.

The crystal Structure of the Dengue virus RNA-dependent RNA polymerase catalytic domain at 1 . 85 Å resolution Running title : Dengue virus NS 5 RdRp structure

Yen-Liang Chen, H. Malet, Ting Xu, 2007 .

A multi-step strategy to obtain crystals of the dengue virus RNA-dependent RNA polymerase that diffract to high resolution.

Yen-Liang Chen, Ting Xu, D. Wen, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

The Potential Role of the ZIKV NS5 Nuclear Spherical-Shell Structures in Cell Type-Specific Host Immune Modulation during ZIKV Infection

S. Vasudevan, Satoru Watanabe, C. P. Gwee, 2019, Cells.

N-sulfonylanthranilic acid derivatives as allosteric inhibitors of dengue viral RNA-dependent RNA polymerase.

P. Niyomrattanakit, Yen-Liang Chen, P. Shi, 2009, Journal of medicinal chemistry.

Dysregulated metabolism underpins Zika-virus-infection-associated impairment in fetal development

S. Vasudevan, Yie Hou Lee, E. Ooi, 2021, Cell Reports.

In Vitro and In Vivo Stability of P884T, a Mutation that Relocalizes Dengue Virus 2 Non-structural Protein 5.

A. Chacko, S. Vasudevan, Menchie Manuel, 2021, ACS infectious diseases.

Zika Virus NS5 Forms Supramolecular Nuclear Bodies That Sequester Importin-α and Modulate the Host Immune and Pro-Inflammatory Response in Neuronal Cells.

J. Forwood, S. Vasudevan, W. Saw, 2019, ACS infectious diseases.

The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production

Moon Y. F. Tay, J. Forwood, S. Vasudevan, 2016, PLoS pathogens.

Structure-guided fragment-based in silico drug design of dengue protease inhibitors

Peter Güntert, Andreas Schüller, M. S. Madhusudhan, 2011, J. Comput. Aided Mol. Des..

NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication

S. Vasudevan, J. Lescar, D. Luo, 2017, Nucleic acids research.

Expression and immunoaffinity purification of recombinant dengue virus 2 NS1 protein as a cleavable SUMOstar fusion.

S. Vasudevan, C. Ruedl, N. Moreland, 2012, Protein expression and purification.

Functional Profiling of Recombinant NS3 Proteases from All Four Serotypes of Dengue Virus Using Tetrapeptide and Octapeptide Substrate Libraries*[boxs]

Jennifer L. Harris, D. Wen, S. Vasudevan, 2005, Journal of Biological Chemistry.

Dengue Virus Selectively Annexes Endoplasmic Reticulum-Associated Translation Machinery as a Strategy for Co-opting Host Cell Protein Synthesis

M. Garcia-Blanco, David W. Reid, C. Nicchitta, 2018, Journal of Virology.

A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice

S. Halstead, M. Wenk, P. Bond, 2019, Science Translational Medicine.

Dysregulated metabolism underpins Zika-virus-infection-associated impairment in fetal development.

S. Vasudevan, Yie Hou Lee, E. Ooi, 2021, Cell reports.

Mutagenesis of the Dengue Virus Type 2 NS5 Methyltransferase Domain*

S. Vasudevan, J. Lescar, A. Davidson, 2008, Journal of Biological Chemistry.

Structure of the Escherichia coli signal transducing protein PII.

D. Ollis, N. Dixon, P. Carr, 1994, Structure.

A scintillation proximity assay for dengue virus NS5 2'-O-methyltransferase-kinetic and inhibition analyses.

D. Wen, S. Vasudevan, J. Lescar, 2008, Antiviral research.

GlnK, a PII-homologue: structure reveals ATP binding site and indicates how the T-loops may be involved in molecular recognition.

H V Westerhoff, H. Westerhoff, D. Ollis, 1998, Journal of molecular biology.

Functionalized sulfonyl anthranilic acid derivatives inhibit replication of all the four dengue serotypes.

S. Vasudevan, S. Alonso, S. Sabatini, 2023, European journal of medicinal chemistry.

Live vaccine infection burden elicits adaptive humoral and cellular immunity required to prevent Zika virus infection

S. Vasudevan, E. Ooi, H. Tan, 2020, EBioMedicine.

Dengue Virus Infection with Highly Neutralizing Levels of Cross-Reactive Antibodies Causes Acute Lethal Small Intestinal Pathology without a High Level of Viremia in Mice

S. Lok, S. Vasudevan, L. Rivino, 2015, Journal of Virology.

Dengue viruses: their evolution, history and emergence as a global public health problem.

D. Gubler, S. Vasudevan, E. Ooi, 2014 .

Biological control of dengue and wolbachia-based strategies

Thomas Walker, D. Gubler, S. Vasudevan, 2014 .

Dengue virus-mosquito interactions and molecular methods of vector control

J. Farrar, D. Gubler, S. Vasudevan, 2014 .

Preclinical Antiviral Testing for Dengue Virus Infection in Mouse Models and Its Association with Clinical Studies.

J. Low, S. Vasudevan, Satoru Watanabe, 2018, ACS infectious diseases.

Therapeutics for flaviviral infections.

S. Vasudevan, Doortje Borrenberghs, Olivia Goethals, 2022, Antiviral research.

Dengue Antiviral Development: A Continuing Journey.

J. Low, A. Sampath, S. Vasudevan, 2018, Advances in Experimental Medicine and Biology.

A fluorescence quenching assay to discriminate between specific and nonspecific inhibitors of dengue virus protease.

A. Caflisch, G. Otting, D. Wen, 2009, Analytical biochemistry.

Establishment of a robust dengue virus NS3-NS5 binding assay for identification of protein-protein interaction inhibitors.

A. Ryo, S. Vasudevan, Young‐Tae Chang, 2012, Antiviral research.

Nuclear Localization of Dengue Virus Nonstructural Protein 5 Through Its Importin α/β–Recognized Nuclear Localization Sequences is Integral to Viral Infection

S. Vasudevan, D. Jans, A. Davidson, 2007, Traffic.

Dengue virus NS4B interacts with NS3 and dissociates it from single-stranded RNA.

A. Sampath, A. Chao, S. Vasudevan, 2006, The Journal of general virology.

A conserved arginine in NS5 binds genomic 3′ stem–loop RNA for primer-independent initiation of flavivirus RNA replication

J. Forwood, S. Vasudevan, J. Lescar, 2021, RNA.

Amidoxime prodrugs convert to potent cell-active multimodal inhibitors of the dengue virus protease.

D. Kiousis, S. Vasudevan, J. Lescar, 2021, European journal of medicinal chemistry.

A Non-structural 1 Protein G53D Substitution Attenuates a Clinically Tested Live Dengue Vaccine.

R. Kini, S. Vasudevan, E. Ooi, 2020, Cell reports.

Title Flexibility of NS 5 Methyltransferase-Polymerase LinkerRegion Is Essential for Dengue Virus Replication

T. Huber, P. Shi, K. Swaminathan, 2017 .

Structural insight and flexible features of NS5 proteins from all four serotypes of Dengue virus in solution.

T. Matsui, T. Weiss, S. Vasudevan, 2015, Acta crystallographica. Section D, Biological crystallography.

Flexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus Replication

T. Huber, P. Shi, K. Swaminathan, 2015, Journal of Virology.

Positive epistasis between viral polymerase and the 3′ untranslated region of its genome reveals the epidemiologic fitness of dengue virus

S. Vasudevan, E. Ooi, H. Tan, 2020, Proceedings of the National Academy of Sciences.

Structure of the N-terminal domain of Escherichia coli glutamine synthetase adenylyltransferase.

D. Ollis, A. Joachimiak, T. Huber, 2004, Structure.

A method for full genome sequencing of all four serotypes of the dengue virus.

Mark J. Schreiber, D. Gubler, M. Hibberd, 2010, Journal of virological methods.

1 Identification of lead-like and non-lead-like inhibitors for dengue virus NS 2 B / NS 3 protease by tryptophan fluorescence

A. Caflisch, G. Otting, D. Wen, 2009 .

On a mouse monoclonal antibody that neutralizes all four dengue virus serotypes.

Soila Sukupolvi-Petty, M. Diamond, S. Vasudevan, 2009, The Journal of general virology.

A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation.

Mohamed Mysara, M. Elhefnawi, S. Vasudevan, 2023, Virology.

Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKV nsP4 suppresses eIF2α phosphorylation

M. Ng, S. Vasudevan, A. Rathore, 2013, Virology Journal.

Unfolded protein response (UPR) gene expression during antibody-dependent enhanced infection of cultured monocytes correlates with dengue disease severity.

D. Gubler, S. Vasudevan, E. Ooi, 2011, Bioscience reports.

Preclinical evaluation of [18F]FDG-PET as a biomarker of lymphoid tissue disease and inflammation in Zika virus infection

A. Chacko, S. Vasudevan, S. Kalimuddin, 2022, European Journal of Nuclear Medicine and Molecular Imaging.

Tissue-specific expansion of Zika virus isogenic variants drive disease pathogenesis

S. Vasudevan, E. Ooi, Satoru Watanabe, 2023, EBioMedicine.

Dengue Virus and Zika Virus Serological Cross-reactivity and Their Impact on Pathogenesis in Mice

S. Vasudevan, Satoru Watanabe, K. W. Chan, 2018, The Journal of infectious diseases.

A Human PrM Antibody That Recognizes a Novel Cryptic Epitope on Dengue E Glycoprotein

S. Lok, P. MacAry, S. Vasudevan, 2012, PloS one.

Nuclear localization of dengue virus nonstructural protein 5 through its importin alpha/beta-recognized nuclear localization sequences is integral to viral infection.

S. Vasudevan, D. Jans, A. Davidson, 2007, Traffic.

A systematic approach to the development of a safe live attenuated Zika vaccine

S. Vasudevan, K. Tryggvason, E. Ooi, 2018, Nature Communications.

Construction and characterization of an infectious clone generated from Chikungunya virus SL11131 strain.

Takeshi Kobayashi, S. Vasudevan, Y. Maeda, 2020, Virology.

Zika virus nonstructural protein 5 residue R681 is critical for dimer formation and enzymatic activity

S. Vasudevan, W. Saw, G. Grüber, 2019, FEBS letters.

The structures of the PII proteins from the cyanobacteria Synechococcus sp. PCC 7942 and Synechocystis sp. PCC 6803.

D. Ollis, K. Forchhammer, P. Carr, 2003, Acta crystallographica. Section D, Biological crystallography.

The structure of the PII-ATP complex.

D. Ollis, T. Huber, P. Carr, 2001, European journal of biochemistry.

18F-FDG as an inflammation biomarker for imaging dengue virus infection and treatment response.

Y. Cheung, A. Chacko, S. Vasudevan, 2017, JCI insight.

Dengue virus infection with highly-neutralizing levels 1 of cross-reactive antibodies cause acute lethal small 2 intestinal pathology without high level of viremia in 3 mice . 4 5 6

S. Lok, S. Vasudevan, L. Rivino, 2015 .

Periodic re-emergence of endemic strains with strong epidemic potential-a proposed explanation for the 2004 Indonesian dengue epidemic.

Mark J. Schreiber, W. Liu, Yen-Liang Chen, 2008, Infection, Genetics and Evolution.

Dengue pathogenesis: host factors.

D. Gubler, S. Vasudevan, E. Ooi, 2014 .

Cholesterol biosynthesis modulation regulates dengue viral replication.

M. Labow, S. Vasudevan, Feng Gu, 2009, Virology.

Development and Evaluation of an Enzyme-Linked Immunosorbent Assay for Dengue Capsid

R. Kuhn, S. Vasudevan, P. Gallay, 2012, The open virology journal.

Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein

S. Vasudevan, E. Ooi, C. Ruedl, 2023, bioRxiv.

A Small-Molecule Dengue Virus Entry Inhibitor

E. Jacoby, S. Vasudevan, W. Schul, 2009, Antimicrobial Agents and Chemotherapy.

Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target.

A. Sampath, S. Vasudevan, J. Lescar, 2008, Antiviral research.

Dengue virus serotype infection specifies the activation of the unfolded protein response

O. Pluquet, S. Vasudevan, Feng Gu, 2007, Virology Journal.

Dengue and dengue hemorrhagic fever.

D. Gubler, S. Vasudevan, E. Ooi, 2014 .

Optimizing celgosivir therapy in mouse models of dengue virus infection of serotypes 1 and 2: The search for a window for potential therapeutic efficacy.

S. Vasudevan, E. Ooi, G. Dow, 2016, Antiviral research.

The domains carrying the opposing activities in adenylyltransferase are separated by a central regulatory domain

D. Ollis, S. Vasudevan, W. V. van Heeswijk, 2007, The FEBS journal.

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