Y. Xiang

发表

Using a combined computational-experimental approach to predict antibody-specific B cell epitopes.

Yanay Ofran, Bjoern Peters, Yan Xiang, 2014, Structure.

Structure Resource Using a Combined Computational-Experimental Approach to Predict Antibody-Specific B Cell Epitopes

Guy Nimrod, B. Peters, Inbal Sela-Culang, 2014 .

Murine Anti-vaccinia Virus D8 Antibodies Target Different Epitopes and Differ in Their Ability to Block D8 Binding to CS-E

Bjoern Peters, L. Hsieh‐Wilson, A. Ward, 2014, PLoS pathogens.

Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective

J. Arnold, C. Cameron, S. Almo, 2021, eLife.

Inhibition of SARS-CoV-2 polymerase by nucleotide analogs: a single molecule perspective

J. Arnold, C. Cameron, S. Almo, 2020, bioRxiv : the preprint server for biology.

Vaccinia Virus A6L Encodes a Virion Core Protein Required for Formation of Mature Virion

Y. Xiang, Xiangzhi Meng, Addie E. Embry, 2006, Journal of Virology.

Vaccinia Virus A6L Encodes a Virion Core Protein Required for Formation of 1

Y. Xiang, Xiangzhi Meng, Addie E. Embry, 2006 .

Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer

Bjoern Peters, T. Kaever, M. R. Benhnia, 2015, PLoS pathogens.

An epitope conserved in orthopoxvirus A13 envelope protein is the target of neutralizing and protective antibodies

Junpeng Deng, Y. Xiang, S. Crotty, 2011, Virology.

Characterization of SARS-CoV-2-specific antibodies in COVID-19 patients reveals highly potent neutralizing IgA

Y. Xiang, W. Zeng, T. Jin, 2021, Signal Transduction and Targeted Therapy.

Discovery of SARS-CoV-2 papain-like protease inhibitors through a combination of high-throughput screening and FlipGFP-based reporter assay

Chunlong Ma, Jun Wang, Y. Xiang, 2021, bioRxiv.

A Unique Bivalent Binding and Inhibition Mechanism by the Yatapoxvirus Interleukin 18 Binding Protein

Junpeng Deng, Y. Xiang, Xiangzhi Meng, 2012, PLoS pathogens.

C7L Family of Poxvirus Host Range Genes Inhibits Antiviral Activities Induced by Type I Interferons and Interferon Regulatory Factor 1

C. Rice, Y. Xiang, Jingxin Cao, 2012, Journal of Virology.

The effect of the vaccinia K1 protein on the PKR-eIF2alpha pathway in RK13 and HeLa cells.

Y. Xiang, Kristen L Willis, J. Shisler, 2009, Virology.

Vaccinia Virus K1L and C7L Inhibit Antiviral Activities Induced by Type I Interferons

Y. Xiang, Jingxin Cao, C. Jiang, 2009, Journal of Virology.

Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron

Y. Xiang, W. Zeng, Yan Wu, 2022, Cell Research.

Monkeypox virus emerges from the shadow of its more infamous cousin: family biology matters

Y. Xiang, A. White, 2022, Emerging microbes & infections.

Yaba Monkey Tumor Virus Encodes a Functional Inhibitor of Interleukin-18

G. McFadden, Y. Xiang, J. Barrett, 2007, Journal of Virology.

Vaccinia Virus Virion Membrane Biogenesis Protein A11 Associates with Viral Membranes in a Manner That Requires the Expression of Another Membrane Biogenesis Protein, A6

Junpeng Deng, Y. Xiang, Xiangzhi Meng, 2012, Journal of Virology.

IL-18 binding and inhibition of interferon gamma induction by human poxvirus-encoded proteins.

B. Moss, Y. Xiang, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Identification of CP77 as the Third Orthopoxvirus SAMD9 and SAMD9L Inhibitor with Unique Specificity for a Rodent SAMD9L

Y. Xiang, Xiangzhi Meng, P. S. Satheshkumar, 2019, Journal of Virology.

Identification of CP77 as the Third Orthopoxvirus SAMD9 and SAMD9L Inhibitor with Unique Specificity for a Rodent SAMD9L

Y. Xiang, Xiangzhi Meng, P. S. Satheshkumar, 2019, Journal of Virology.

Structure Function Studies of Vaccinia Virus Host Range Protein K1 Reveal a Novel Functional Surface for Ankyrin Repeat Proteins (cid:1)

Junpeng Deng, Y. Xiang, Xiangzhi Meng, 2010 .

Identification from diverse mammalian poxviruses of host-range regulatory genes functioning equivalently to vaccinia virus C7L.

Y. Xiang, Xiangzhi Meng, J. Chao, 2008, Virology.

Mutation of vaccinia virus gene G2R causes suppression of gene A18R ts mutants: implications for control of transcription.

R. Condit, Y. Xiang, J. Lewis, 1996, Virology.

Correspondence of the Functional Epitopes of Poxvirus and Human Interleukin-18-Binding Proteins

B. Moss, Y. Xiang, 2001, Journal of Virology.

Expedited Approach toward the Rational Design of Noncovalent SARS-CoV-2 Main Protease Inhibitors

S. Cherry, Chunlong Ma, Jun Wang, 2021, Journal of medicinal chemistry.

An expedited approach towards the rationale design of non-covalent SARS-CoV-2 main protease inhibitors with in vitro antiviral activity

S. Cherry, Chunlong Ma, Jun Wang, 2020, bioRxiv.

ROLE OF HUMAN BETA DEFENSIN-2 DURING TUMOR NECROSIS FACTOR- α /NF- κ B MEDIATED INNATE ANTI-VIRAL RESPONSE AGAINST HUMAN RESPIRATORY SYNCYTIAL VIRUS

Y. Xiang, Xiangzhi Meng, T. Chang, 2008 .

RNA granules associated with SAMD9-mediated poxvirus restriction are similar to antiviral granules in composition but do not require TIA1 for poxvirus restriction.

Y. Xiang, Xiangzhi Meng, 2019, Virology.

Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox

Bjoern Peters, T. Kaever, M. Matho, 2016, Journal of Virology.

Generation and characterization of monoclonal antibodies specific for vaccinia virus.

Y. Xiang, Xiangzhi Meng, 2012, Methods in molecular biology.

Immune-defense molecules of molluscum contagiosum virus, a human poxvirus.

B. Moss, Y. Xiang, T. Senkevich, 2000, Trends in microbiology.

Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity

Hao Tan, Chunlong Ma, Jun Wang, 2021, Journal of the American Chemical Society.

Orthopoxvirus IL-18 binding proteins: affinities and antagonist activities.

B. Moss, Y. Xiang, S. Calderara, 2001, Virology.

Potent in vitro Neutralization of SARS-CoV-2 by Hetero-bivalent Alpaca Nanobodies Targeting the Spike Receptor-Binding Domain

Y. Xiang, Xiangzhi Meng, W. Zeng, 2021, bioRxiv.

Corrigendum: Activation of innate immune antiviral responses by Nod2

K. Tominaga, Y. Xiang, Victoria Frohlich, 2010, Nature Immunology.

Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against Mpro and cathepsin L

Chunlong Ma, Jun Wang, Y. Xiang, 2020, Science Advances.

Potent Neutralization of SARS-CoV-2 by Hetero-Bivalent Alpaca Nanobodies Targeting the Spike Receptor-Binding Domain

Y. Xiang, Xiangzhi Meng, T. Jin, 2021, Journal of Virology.

A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection

Y. Xiang, Xiangzhi Meng, Chuanping Si, 2018, PLoS pathogens.

Activation of innate immune antiviral response by NOD2

Kaoru Tominaga, Santanu Bose, Yan Xiang, 2009, Nature Immunology.

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against Mpro and cathepsin L

Chunlong Ma, Jun Wang, Y. Xiang, 2020, bioRxiv.

Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay

Chunlong Ma, Jun Wang, Y. Xiang, 2021, ACS central science.

Structure of the unique tetrameric STENOFOLIA homeodomain bound with target promoter DNA

Junpeng Deng, Y. Xiang, M. Tadege, 2021, Acta crystallographica. Section D, Structural biology.

The in vitro antiviral activity of lactoferrin against common human coronaviruses and SARS-CoV-2 is mediated by targeting the heparan sulfate co-receptor

Jun Wang, Y. Xiang, Xiangzhi Meng, 2021, Emerging microbes & infections.

Development of an animal model of progressive vaccinia in nu/nu mice and the use of bioluminescence imaging for assessment of the efficacy of monoclonal antibodies against vaccinial B5 and L1 proteins

Y. Xiang, S. Crotty, H. Golding, 2017, Antiviral research.

Structure and function of an effector domain in antiviral factors and tumor suppressors SAMD9 and SAMD9L

Junpeng Deng, Shu-Bing Qian, Y. Xiang, 2022, Proceedings of the National Academy of Sciences.

Generation and characterization of a large panel of murine monoclonal antibodies against vaccinia virus.

G. Zhong, Y. Xiang, Shan Lu, 2011, Virology.

Vaccinia Virus A6 Is Essential for Virion Membrane Biogenesis and Localization of Virion Membrane Proteins to Sites of Virion Assembly

Y. Xiang, Xiangzhi Meng, Addie E. Embry, 2012, Journal of Virology.

Potent Neutralization of Vaccinia Virus by Divergent Murine Antibodies Targeting a Common Site of Vulnerability in L1 Protein

Bjoern Peters, Inbal Sela-Culang, Y. Ofran, 2014, Journal of Virology.

Rescue of a Vaccinia Virus Mutant Lacking IFN Resistance Genes K1L and C7L by the Parapoxvirus Orf Virus

Y. Xiang, A. Mercer, S. Fleming, 2020, Frontiers in Microbiology.

Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins

Junpeng Deng, Y. Xiang, Xiangzhi Meng, 2015, Proceedings of the National Academy of Sciences.

The vaccinia virus bifunctional gene J3 (nucleoside-2'-O-)-methyltransferase and poly(A) polymerase stimulatory factor is implicated as a positive transcription elongation factor by two genetic approaches.

R. Condit, Y. Xiang, J. Lewis, 2000, Virology.

Transcription elongation activity of the vaccinia virus J3 protein in vivo is independent of poly(A) polymerase stimulation.

R. Condit, Y. Xiang, D. Latner, 2000, Virology.

Responses to the Smallpox Vaccine Resistance Revealed in Human Antibody

D. Burton, Bjoern Peters, J. Crowe, 2014 .

Unusual Features of Vaccinia Virus Extracellular Virion Form Neutralization Resistance Revealed in Human Antibody Responses to the Smallpox Vaccine

D. Burton, Bjoern Peters, J. Crowe, 2012, Journal of Virology.

Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir

Chunlong Ma, Jun Wang, Y. Xiang, 2021, ACS pharmacology & translational science.

Inhibition of vesicular stomatitis virus infection in epithelial cells by alpha interferon-induced soluble secreted proteins.

Y. Xiang, Xiangzhi Meng, A. Banerjee, 2006, The Journal of general virology.

Identification of small molecule inhibitors of Interleukin-18

Junpeng Deng, Y. Xiang, Xiangzhi Meng, 2017, Scientific Reports.

Structural biology of the IL‐1 superfamily: Key cytokines in the regulation of immune and inflammatory responses

Junpeng Deng, Y. Xiang, B. Krumm, 2014, Protein science : a publication of the Protein Society.

Kinetic Multi-omic Analysis of Responses to SARS-CoV-2 Infection in a Model of Severe COVID-19

Yanbao Yu, Y. Xiang, Yi-Han Lin, 2021, Journal of virology.

Sensing and signaling of immunogenic extracellular RNAs restrain group 2 innate lymphoid cell-driven acute lung inflammation and airway hyperresponsiveness

E. Brooks, Xin Zhang, Y. Xiang, 2020, PloS one.

Role of Human β-Defensin-2 during Tumor Necrosis Factor-α/NF-κB-mediated Innate Antiviral Response against Human Respiratory Syncytial Virus*

Y. Xiang, Xiangzhi Meng, T. Chang, 2008, Journal of Biological Chemistry.

BATF3-dependent induction of IL-27 in B cells bridges the innate and adaptive stages of the antibody response

C. Hunter, Yidong Chen, P. Casali, 2020, bioRxiv.

Crystallization of interleukin-18 for structure-based inhibitor design.

Junpeng Deng, Y. Xiang, Xiangzhi Meng, 2015, Acta crystallographica. Section F, Structural biology communications.

Structural basis for antagonism of human interleukin 18 by poxvirus interleukin 18-binding protein

Junpeng Deng, Y. Xiang, Xiangzhi Meng, 2008, Proceedings of the National Academy of Sciences.

Identification of human and mouse homologs of the MC51L-53L-54L family of secreted glycoproteins encoded by the Molluscum contagiosum poxvirus.

B. Moss, Y. Xiang, Bernard Moss, 1999, Virology.

Molluscum Contagiosum Virus Interleukin-18 (IL-18) Binding Protein Is Secreted as a Full-Length Form That Binds Cell Surface Glycosaminoglycans through the C-Terminal Tail and a Furin-Cleaved Form with Only the IL-18 Binding Domain

B. Moss, Y. Xiang, 2003, Journal of Virology.

Structural and Biochemical Characterization of the Vaccinia Virus Envelope Protein D8 and Its Recognition by the Antibody LA5

Bjoern Peters, M. R. Benhnia, M. Matho, 2012, Journal of Virology.

Enigmatic origin of the poxvirus membrane from the endoplasmic reticulum shown by 3D imaging of vaccinia virus assembly mutants

B. Moss, E. Fischer, Y. Xiang, 2017, Proceedings of the National Academy of Sciences.

Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer

Junpeng Deng, Y. Xiang, Xiangzhi Meng, 2018, Proceedings of the National Academy of Sciences.

Molecular Cloning and Characterization of Orthologues of NPR1 Gene from Poplar

Y. Xiang, B. Cheng, Hongsheng He, 2013 .

Enhancement of immune response to an antigen delivered by vaccinia virus by displaying the antigen on the surface of intracellular mature virion.

Y. Xiang, Xiangzhi Meng, P. Dube, 2011, Vaccine.

Molecular analysis of the cucumber leaf spot virus genome.

Y. Xiang, M. Robbins, R. Reade, 2003, Virus research.

Structure Function Studies of Vaccinia Virus Host Range Protein K1 Reveal a Novel Functional Surface for Ankyrin Repeat Proteins

Junpeng Deng, Y. Xiang, Xiangzhi Meng, 2010, Journal of Virology.

The Nucleocapsid Proteins of SARS-CoV-2 and Its Close Relative Bat Coronavirus RaTG13 Are Capable of Inhibiting PKR- and RNase L-Mediated Antiviral Pathways

Y. Xiang, Jingxin Cao, D. Kobasa, 2023, Microbiology spectrum.

Polyvalent mRNA vaccination elicited potent immune response to monkeypox virus surface antigens

Y. Xiang, Sidi Chen, C. Lucas, 2023, Cell Research.

Structure–function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8

Bjoern Peters, K. Ley, L. Hsieh‐Wilson, 2017, The Journal of Biological Chemistry.

Human antibody responses to vaccinia virus D 8 1 Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D 8

Bjoern Peters, K. Ley, L. Hsieh‐Wilson, 2017 .

Analysis of the Role of Vaccinia Virus H7 in Virion Membrane Biogenesis with an H7-Deletion Mutant

Junpeng Deng, Y. Xiang, Xiangzhi Meng, 2013, Journal of Virology.

Variola virus IL-18 binding protein interacts with three human IL-18 residues that are part of a binding site for human IL-18 receptor alpha subunit.

Y. Xiang, Xiangzhi Meng, Michael A. Leman, 2007, Virology.

Structure-Function Analysis of Vaccinia Virus H7 Protein Reveals a Novel Phosphoinositide Binding Fold Essential for Poxvirus Replication

C. Cameron, Junpeng Deng, Y. Xiang, 2014, Journal of Virology.

Characterization of murine antibody responses to vaccinia virus envelope protein A14 reveals an immunodominant antigen lacking of effective neutralization targets.

Bjoern Peters, T. Kaever, Y. Xiang, 2018, Virology.

Identification of In Vitro Inhibitors of Monkeypox Replication

Y. Xiang, M. Lorenzo, R. Blasco, 2023, Microbiology spectrum.

Antivirals against monkeypox infections

Y. Xiang, M. Lorenzo, R. Blasco, 2023, bioRxiv.

Human SAMD9 is a poxvirus-activatable anticodon nuclease inhibiting codon-specific protein synthesis

Junpeng Deng, Shu-Bing Qian, Y. Xiang, 2023, Science advances.

Vaccinia virus K1L protein supports viral replication in human and rabbit cells through a cell-type-specific set of its ankyrin repeat residues that are distinct from its binding site for ACAP2.

Y. Xiang, Xiangzhi Meng, 2006, Virology.