N. Shimba

发表

Rapid identification of protein-protein interfaces for the construction of a complex model based on multiple unassigned signals by using time-sharing NMR measurements.

Y. Fukunishi, V. Dötsch, M. Reese, 2011, Journal of structural biology.

Crystal structure and enhanced activity of a cutinase‐like enzyme from Cryptococcus sp. strain S‐2

Yuya Kodama, N. Shimba, E. Suzuki, 2009, Proteins.

Curculin Exhibits Sweet-tasting and Taste-modifying Activities through Its Distinct Molecular Surfaces*

N. Shimba, E. Suzuki, E. Kurimoto, 2007, Journal of Biological Chemistry.

Collagen-binding mode of vWF-A3 domain determined by a transferred cross-saturation experiment

N. Shimba, E. Suzuki, I. Shimada, 2003, Nature Structural Biology.

Letter to the Editor: Backbone 1H, 13C, and 15N resonance assignments of the von Willebrand factor A3 domain

N. Shimba, E. Suzuki, I. Shimada, 2002, Journal of biomolecular NMR.

Clinical Implementation of Metabolomics

Shunji Takahashi, N. Shimba, Takeshi Kimura, 2012 .

Crystal structure of Bifidobacterium Longum phosphoketolase; key enzyme for glucose metabolism in Bifidobacterium

Kazutoshi Takahashi, N. Shimba, E. Suzuki, 2010, FEBS letters.

Plasma amino acid profiles are associated with insulin, C-peptide and adiponectin levels in type 2 diabetic patients

N. Shimba, Y. Noguchi, H. Miyano, 2014, Nutrition & Diabetes.

NMR-based screening method for transglutaminases: rapid analysis of their substrate specificities and reaction rates.

N. Shimba, E. Suzuki, K. Yokoyama, 2002, Journal of agricultural and food chemistry.

A Cost Benefit Analysis of AminoIndex Cancer Screening in Japan

N. Shimba, T. Muramatsu, A. Imaizumi, 2015 .

Rapid identification of ligand-binding sites by using an assignment-free NMR approach.

Yuya Kodama, N. Shimba, E. Suzuki, 2013, Journal of medicinal chemistry.

Structural comparison between wild-type and P25S human cystatin A by NMR spectroscopy. Does this mutation affect the α-helix conformation ?

M. Kainosho, N. Shimba, H. Kaji, 2004, Journal of Structural and Functional Genomics.

Methyl groups as probes for proteins and complexes in in-cell NMR experiments.

P. Ortiz de Montellano, C. Craik, V. Dötsch, 2004, Journal of the American Chemical Society.

Regulating the Activity of the Herpesviral Protease and Its Viable Target for Inhibition

N. Shimba, 2006 .

Screening for improved activity of a transglutaminase from Streptomyces mobaraensis created by a novel rational mutagenesis and random mutagenesis

N. Shimba, E. Suzuki, S. Taguchi, 2010, Applied Microbiology and Biotechnology.

Structural-Based Engineering for Transferases to Improve the Industrial Production of 5′-Nucleotides

N. Shimba, E. Suzuki, Y. Asano, 2007 .

High expression with Corynebacterium glutamicum for nuclear magnetic resonance sample preparation.

N. Shimba, E. Suzuki, T. Mizukoshi, 2005, Analytical biochemistry.

Incorporation of 15N-labeled ammonia into glutamine amide groups by protein-glutaminase and analysis of the reactivity for α-lactalbumin.

N. Shimba, E. Suzuki, K. Sonomoto, 2011, Journal of agricultural and food chemistry.

New Sequential‐Assignment Routes of Nucleic Acid NMR Signals Using a [5′‐13C]‐Labeled DNA Dodecamer

C. Kojima, N. Shimba, E. Suzuki, 2004, Nucleosides, nucleotides & nucleic acids.

[NMR analysis of a contaminant in heparin].

N. Shimba, E. Suzuki, H. Miyano, 2008, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Haliangicin, a novel antifungal metabolite produced by a marine myxobacterium. 2. Isolation and structural elucidation.

N. Shimba, S. Sato, S. Yamanaka, 2001, The Journal of antibiotics.

A study of chiral recognition for NBD-derivatives on a Pirkle-type chiral stationary phase.

N. Shimba, T. Fukushima, K. Imai, 2001, Biomedical chromatography : BMC.

Monitoring the hydrolysis and transglycosylation activity of alpha-glucosidase from Aspergillus niger by nuclear magnetic resonance spectroscopy and mass spectrometry.

N. Shimba, E. Suzuki, N. Yamada, 2009, Analytical biochemistry.

Comparative thermodynamic analyses of the Fv, Fab* and Fab and Fab fragments of anti‐dansyl mouse monoclonal antibody

A. Sarai, N. Shimba, I. Shimada, 1995 .

Enhancement of nucleoside phosphorylation activity in an acid phosphatase.

N. Shimba, E. Suzuki, Y. Asano, 2002, Protein engineering.

One functional switch mediates reversible and irreversible inactivation of a herpesvirus protease.

C. Craik, V. Dötsch, N. Shimba, 2006, Biochemistry.

Substrate specificity of microbial transglutaminase as revealed by three-dimensional docking simulation and mutagenesis

T. Hirokawa, N. Shimba, E. Suzuki, 2009, Protein engineering, design & selection : PEDS.

Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population

T. Kawaguchi, R. Yamada, F. Matsuda, 2019, European Journal of Human Genetics.

Structural basis of the transition-state stabilization in antibody-catalyzed hydrolysis.

N. Shimba, I. Shimada, Hideo Takahashi, 2007, Journal of molecular biology.

Enzymatic labeling of arbitrary proteins.

N. Shimba, E. Suzuki, K. Yokoyama, 2002, Analytical biochemistry.

Crystal Structure of Bifidobacterium Longum Phosphoketolase

Kazutoshi Takahashi, N. Shimba, E. Suzuki, 2010 .

Enhancement of transglutaminase activity by NMR identification of its flexible residues affecting the active site

D. Ejima, N. Shimba, K. Ishikawa, 2002, FEBS letters.

31P NMR studies of energy metabolism in xanthosine-5'-monophosphate overproducing Corynebacterium ammoniagenes.

N. Shimba, E. Suzuki, S. Sugimoto, 2003, European journal of biochemistry.

Determination of Protonation and Deprotonation Forms and Tautomeric States of Histidine Residues in Large Proteins Using Nitrogen−Carbon J Couplings in Imidazole Ring

N. Shimba, I. Shimada, Hideo Takahashi, 1998 .

The energetic conversion competence of Escherichia coli during aerobic respiration studied by 31P NMR using a circulating fermentation system.

Yasushi Noguchi, Yoshio Kawahara, Ei-Ichiro Suzuki, 2004, Journal of biochemistry.

Quantitative identification of the protonation state of histidines in vitro and in vivo.

C. Craik, V. Dötsch, N. Shimba, 2003, Biochemistry.

In vivo NMR system for evaluating oxygen-dependent metabolic status in microbial culture.

N. Shimba, E. Suzuki, S. Sugimoto, 2002, Journal of microbiological methods.

Communication between the active sites and dimer interface of a herpesvirus protease revealed by a transition-state inhibitor.

P. Ortiz de Montellano, C. Craik, N. Shimba, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population

T. Kawaguchi, R. Yamada, F. Matsuda, 2019, European Journal of Human Genetics.

Direct determination of the insulin-insulin receptor interface using transferred cross-saturation experiments.

N. Shimba, E. Suzuki, I. Shimada, 2010, Journal of medicinal chemistry.

Herpesvirus Protease Inhibition by Dimer Disruption

Charles S. Craik, C. Craik, N. Shimba, 2004, Journal of Virology.

The pH-dependent structural variation of complementarity-determining region H3 in the crystal structures of the Fv fragment from an anti-dansyl monoclonal antibody.

N. Shimba, I. Shimada, M. Nakasako, 1999, Journal of molecular biology.

Optimization of 13C direct detection NMR methods

Alan S. Stern, Jeffrey C. Hoch, Volker Dötsch, 2004, Journal of biomolecular NMR.

The NMR structure of protein-glutaminase from Chryseobacterium proteolyticum

N. Shimba, E. Suzuki, K. Ogura, 2010, Journal of biomolecular NMR.

Induced structure of a helical switch as a mechanism to regulate enzymatic activity

Volker Dötsch, C. Craik, V. Dötsch, 2005, Nature Structural &Molecular Biology.

Elimination of 13Calpha splitting in protein NMR spectra by deconvolution with maximum entropy reconstruction.

Volker Dötsch, Jeffrey C Hoch, Alan S Stern, 2003, Journal of the American Chemical Society.