I. Shimada

发表

Rapid identification of protein-protein interfaces for the construction of a complex model based on multiple unassigned signals by using time-sharing NMR measurements.

Y. Fukunishi, V. Dötsch, M. Reese, 2011, Journal of structural biology.

Three-dimensional solution structure of the B domain of staphylococcal protein A: comparisons of the solution and crystal structures.

I. Shimada, H. Gouda, H. Torigoe, 1992, Biochemistry.

Structural Basis of Efficient Electron Transport between Photosynthetic Membrane Proteins and Plastocyanin in Spinach Revealed Using Nuclear Magnetic Resonance[C][W][OA]

I. Shimada, K. Sode, Takumi Ueda, 2012, Plant Cell.

A novel NMR method for determining the interfaces of large protein–protein complexes

Hideo Takahashi, Ichio Shimada, I. Shimada, 2000, Nature Structural Biology.

N-terminal half of a mitochondrial presequence peptide takes a helical conformation when bound to dodecylphosphocholine micelles: a proton nuclear magnetic resonance study.

I. Shimada, F. Inagaki, T. Endo, 1989, Journal of biochemistry.

Structural Basis of the Interaction between Chemokine Stromal Cell-derived Factor-1/CXCL12 and Its G-protein-coupled Receptor CXCR4*

Hideo Takahashi, Masako Hirose, Kouji Matsushima, 2009, The Journal of Biological Chemistry.

A 1H-NMR study of the solution conformation of cyclo(GRGDSPA): conformational effects on the physiological activity.

I. Shimada, Y. Arata, R. Mizutani, 1992, Biochemical and biophysical research communications.

Dynamic domain arrangement of CheA-CheY complex regulates bacterial thermotaxis, as revealed by NMR

I. Shimada, Takumi Ueda, Hideo Iwaï, 2017, Scientific Reports.

Frequency selective coherence transfer NMR spectroscopy to study the structural dynamics of high molecular weight proteins.

I. Shimada, Y. Toyama, 2019, Journal of magnetic resonance.

HNCA-TOCSY-CANH experiments with alternate 13C-12C labeling: a set of 3D experiment with unique supra-sequential information for mainchain resonance assignment

G. Wagner, I. Shimada, Hideo Takahashi, 2011, Journal of biomolecular NMR.

Structure determination of a protein assembly by amino acid selective cross‐saturation

Y. Fukunishi, Haruki Nakamura, Eiji Kanamori, 2011, Proteins.

Evidence for the Direct Interaction of Spermine with the Inwardly Rectifying Potassium Channel*

I. Shimada, T. Muramatsu, M. Osawa, 2009, The Journal of Biological Chemistry.

NMR techniques for identifying the interface of a larger protein-protein complex: cross-saturation and transferred cross-saturation experiments.

I. Shimada, 2005, Methods in enzymology.

Production of isotopically labeled heterologous proteins in non-E. coli prokaryotic and eukaryotic cells

I. Shimada, Hideo Takahashi, H. Takahashi, 2010, Journal of biomolecular NMR.

Isotopic labeling of heterologous proteins in the yeast Pichia pastoris and Kluyveromyces lactis.

I. Shimada, Hideo Takahashi, T. Sugiki, 2012, Methods in molecular biology.

Stable isotope labeling of protein by Kluyveromyces lactis for NMR study

I. Shimada, Hideo Takahashi, T. Sugiki, 2008, Journal of biomolecular NMR.

Structural basis of the KcsA K(+) channel and agitoxin2 pore-blocking toxin interaction by using the transferred cross-saturation method.

Haruki Nakamura, I. Shimada, Hideo Takahashi, 2003, Structure.

Targeting the cryptic sites: NMR-based strategy to improve protein druggability by controlling the conformational equilibrium

I. Shimada, H. Hanzawa, Misaki Imai, 2020, Science Advances.

Collagen-binding mode of vWF-A3 domain determined by a transferred cross-saturation experiment

N. Shimba, E. Suzuki, I. Shimada, 2003, Nature Structural Biology.

Hyaluronan Recognition Mode of CD44 Revealed by Cross-saturation and Chemical Shift Perturbation Experiments*

Yoshiki Yamaguchi, Ichio Shimada, Masayoshi Sakakura, 2003, Journal of Biological Chemistry.

Direct determination of a membrane-peptide interface using the nuclear magnetic resonance cross-saturation method.

I. Shimada, Hideo Takahashi, T. Kohno, 2005, Biophysical journal.

Bead-linked proteoliposomes: a reconstitution method for nmr analyses of membrane protein-ligand interactions.

I. Shimada, K. Takeuchi, M. Yokogawa, 2005, Journal of the American Chemical Society.

Letter to the Editor: Backbone 1H, 13C, and 15N resonance assignments of the von Willebrand factor A3 domain

N. Shimba, E. Suzuki, I. Shimada, 2002, Journal of biomolecular NMR.

Structural Genomics of Membrane Proteins

N. Nomura, Haruki Nakamura, Y. Kyōgoku, 2003 .

Differential N-Glycan Patterns of Secreted and Intracellular IgG Produced in Trichoplusia ni Cells*

M. Betenbaugh, I. Shimada, K. Masuda, 1997, The Journal of Biological Chemistry.

Nuclear magnetic resonance approaches for characterizing interactions between the bacterial chaperonin GroEL and unstructured proteins.

Masasuke Yoshida, I. Shimada, M. Yagi-Utsumi, 2013, Journal of bioscience and bioengineering.

Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR

I. Shimada, A. Shukla, Takumi Ueda, 2021, Nature Communications.

Structural equilibrium underlying ligand-dependent activation of β2-adrenoreceptor

I. Shimada, Takumi Ueda, Yutaka Kofuku, 2020, Nature Chemical Biology.

Nuclear Magnetic Resonance Approaches for Characterizing Protein-Protein Interactions.

I. Shimada, M. Osawa, Y. Toyama, 2018, Methods in molecular biology.

Allosteric enhancement of MAP kinase p38α's activity and substrate selectivity by docking interactions

I. Shimada, Hideo Takahashi, K. Takeuchi, 2014, Nature Structural &Molecular Biology.

Characterization of the multimeric structure of poly(A)-binding protein on a poly(A) tail

S. Hoshino, I. Shimada, K. Mio, 2018, Scientific Reports.

Nitrogen-detected TROSY yields comparable sensitivity to proton-detected TROSY for non-deuterated, large proteins under physiological salt conditions

G. Wagner, I. Shimada, H. Arthanari, 2016, Journal of biomolecular NMR.

Nitrogen detected TROSY at high field yields high resolution and sensitivity for protein NMR

G. Wagner, I. Shimada, H. Arthanari, 2015, Journal of biomolecular NMR.

Nickel binding to NikA: an additional binding site reconciles spectroscopy, calorimetry and crystallography.

A. Kidera, S. Fuchigami, M. Ikeguchi, 2007, Acta crystallographica. Section D, Biological crystallography.

Relayed HOHAHA, a useful method for extracting subspectra of individual components of sugar chains

A. Bax, D. Kohda, I. Shimada, 1989 .

Chondroitin sulfate E fragments enhance CD44 cleavage and CD44-dependent motility in tumor cells.

I. Shimada, K. Sugahara, Shinji Ogino, 2008, Cancer research.

1H and 13C NMR assignments for the glycans in glycoproteins by using 2H/13C-labeled glucose as a metabolic precursor

I. Shimada, Y. Yamaguchi, Y. Arata, 2000, Journal of biomolecular NMR.

Dynamics of the carbohydrate chains attached to the Fc portion of immunoglobulin G as studied by NMR spectroscopy assisted by selective 13C labeling of the glycans

M. Shindo, K. Koga, I. Shimada, 1998, Journal of biomolecular NMR.

Identification of neutral and sialyl N-linked oligosaccharide structures from human serum glycoproteins using three kinds of high-performance liquid chromatography.

I. Shimada, Y. Arata, H. Nakagawa, 1995, Analytical biochemistry.

Three novel oligosaccharides with the sialyl-Lea structure in human milk: isolation by immunoaffinity chromatography.

H. Kitagawa, I. Shimada, H. Nakada, 1989, Biochemistry.

Occurrence of tetra- and pentasaccharides with the sialyl-Le(a) structure in human milk.

H. Kitagawa, I. Shimada, F. Inagaki, 1990, The Journal of biological chemistry.

Structural elucidation of a variety of GalNAc-containing N-linked oligosaccharides from human urinary kallidinogenase.

I. Shimada, H. Hanzawa, Y. Arata, 1993, The Journal of biological chemistry.

The Carbohydrate Moiety of the Bermuda Grass Antigen BG60

I. Shimada, Y. Arata, H. Nakagawa, 1996, The Journal of Biological Chemistry.

Structural basis of the interaction between IgG and fcγ receptors

C. Sautès-Fridman, W. Fridman, I. Shimada, 2000 .

Rapid Preparation of Stable Isotope Labeled Peptides that Bind to Target Proteins by a Phage Library System

I. Shimada, Hideo Takahashi, Yumiko Mizukoshi, 2006, Journal of biomolecular NMR.

Identification of a binding element for the cytoplasmic regulator FROUNT in the membrane-proximal C-terminal region of chemokine receptors CCR2 and CCR5.

K. Matsushima, M. Suwa, I. Shimada, 2014, The Biochemical journal.

Effector functions of a mouse IgG that lacks the entire CH1 domain. C1q binding and complement fixation in the absence of antigen.

I. Shimada, Y. Arata, R. Mizutani, 1993, Journal of immunology.

31P NMR study of the interactions between oligodeoxynucleotides containing (6‐4) photoproduct and Fab fragments of monoclonal antibodies specific for (6‐4) photoproduct

Y. Komatsu, T. Torizawa, O. Nikaido, 1998, FEBS letters.

Specificities and rates of binding of anti-(6-4) photoproduct antibody fragments to synthetic thymine photoproducts.

T. Torizawa, O. Nikaido, E. Ohtsuka, 1998, Journal of biochemistry.

Rapid identification of ligand-binding sites by using an assignment-free NMR approach.

Yuya Kodama, N. Shimba, E. Suzuki, 2013, Journal of medicinal chemistry.

N-glycan structures of a recombinant mouse soluble Fcgamma receptor II.

I. Shimada, K. Masuda, H. Araki, 1998, Glycoconjugate journal.

Oligomers of glycamino acid.

I. Shimada, Y. Yamaguchi, R. Schnaar, 2002, Bioorganic & medicinal chemistry.

Synthesis and characterization of sapecin and sapecin B

I. Shimada, Kazuki Sato, S. Kurata, 1994, FEBS letters.

Segmental isotopic labeling of a 140 kDa dimeric multi-domain protein CheA from Escherichia coli by expressed protein ligation and protein trans-splicing

I. Shimada, Takumi Ueda, Hideo Iwaï, 2012, Journal of biomolecular NMR.

Elucidation of the CCR1- and CCR5-binding modes of MIP-1α by application of an NMR spectra reconstruction method to the transferred cross-saturation experiments

I. Shimada, Takumi Ueda, M. Matsumoto, 2015, Journal of Biomolecular NMR.

Deletion of D-helix in bovine pancreatic phospholipase A2.

T. Tanaka, I. Shimada, F. Inagaki, 1990, Agricultural and biological chemistry.

Molecular Basis of the High-Affinity Activation of Skeletal Ryanodine Receptor Ca^ -Release Channel by Imperatoxin A

I. Shimada, Hideo Takahashi, Kazuki Sato, 2005 .

Interactions of High Affinity Anti (6-4) Photoproduct Antibody Fragments with Damaged DNA

Y. Komatsu, Y. Satow, O. Nikaido, 1999 .

Purification and Characterization of N-β-Alanyl-5-S-glutathionyl-3,4-dihydroxyphenylalanine, a Novel Antibacterial Substance of Sarcophaga peregrina (Flesh Fly)*

I. Shimada, S. Kurata, S. Natori, 1996, The Journal of Biological Chemistry.

NMR assignments of the N-glycans of the Fc fragment of mouse immunoglobulin G2b glycoprotein

I. Shimada, Koichi Kato, Y. Yamaguchi, 2021, Biomolecular NMR assignments.

Ultrafast water permeation through nanochannels with a densely fluorous interior surface

T. Aida, H. Noji, J. Shiomi, 2022, Science.

Efficient chemical synthesis of a pyrimidine (6–4) pyrimidone photoproduct analog and its properties

Y. Komatsu, T. Torizawa, O. Nikaido, 2000 .

Function-related dynamics of GPCRs.

I. Shimada, Takumi Ueda, Shunsuke Imai, 2022, Journal of magnetic resonance.

Conformational equilibrium defines the variable induction of the multidrug-binding transcriptional repressor QacR

I. Shimada, Misaki Imai, K. Takeuchi, 2019, Proceedings of the National Academy of Sciences.

Structural basis for two-way communication between dynein and microtubules

I. Shimada, M. Kikkawa, N. Nishida, 2019, Nature Communications.

Solid-state 17O NMR analysis of synthetically 17O-enriched d-glucosamine

I. Shimada, Yoshinori Uekusa, Takumi Yamaguchi, 2020, Chemical Physics Letters.

GPCR drug discovery: integrating solution NMR data with crystal and cryo-EM structures

Kurt Wüthrich, Ichio Shimada, Matthew T. Eddy, 2018, Nature Reviews Drug Discovery.

Binding modes of inhibitors to ribonuclease T1 as elucidated by the analysis of two-dimensional NMR.

I. Shimada, F. Inagaki, 1990, Nucleic acids symposium series.

Investigation of the Cyclobutane Pyrimidine Dimer (CPD) Photolyase DNA Recognition Mechanism by NMR Analyses*

T. Todo, K. Morikawa, T. Torizawa, 2004, Journal of Biological Chemistry.

A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis

K. Shin‐ya, T. Hirokawa, I. Shimada, 2017, The Journal of Biological Chemistry.

A structural study of the asparagine-linked oligosaccharide moiety of duck ovomucoid

I. Shimada, T. Matsuda, Y. Arata, 1993, Glycoconjugate Journal.

Structural study of the oligosaccharide moieties of sphingolipid activator proteins, saposins A, C and D obtained from the spleen of a Gaucher patient.

K Ito, I. Shimada, Y. Kishimoto, 1993, European journal of biochemistry.

Backbone resonance assignment for the outer membrane lipoprotein receptor LolB from Escherichia coli

I. Shimada, Hideo Takahashi, H. Tokuda, 2007, Biomolecular NMR assignments.

Structure-Based Development of a Protein-Protein Interaction Inhibitor Targeting Tumor Necrosis Factor Receptor-Associated Factor 6.

Y. Fukunishi, I. Shimada, A. Inoue, 2015, Journal of medicinal chemistry.

Paip2A inhibits translation by competitively binding to the RNA recognition motifs of PABPC1 and promoting its dissociation from the poly(A) tail

S. Hoshino, I. Shimada, N. Hosoda, 2022, The Journal of biological chemistry.

Biological role of the two overlapping poly(A)-binding protein interacting motifs 2 (PAM2) of eukaryotic releasing factor eRF3 in mRNA decay.

S. Hoshino, T. Katada, I. Shimada, 2012, RNA.

Nitrogen detected TROSY at high field yields high resolution and sensitivity for protein NMR

G. Wagner, I. Shimada, H. Arthanari, 2015, Journal of Biomolecular NMR.

Sequential 1H NMR assignments and secondary structure of the B domain of staphylococcal protein A: structural changes between the free B domain in solution and the Fc-bound B domain in crystal.

I. Shimada, H. Torigoe, A. Saito, 1990, Biochemistry.

Pairwise NMR experiments for the determination of protein backbone dihedral angle Φ based on cross-correlated spin relaxation

I. Shimada, Hideo Takahashi, 2007, Journal of biomolecular NMR.

Nuclear magnetic resonance study of antibodies: a multinuclear approach.

I. Shimada, Y. Arata, H. Takahashi, 1994, Methods in enzymology.

Backbone resonance assignments for G protein αi3 subunit in the GDP-bound state

I. Shimada, M. Osawa, M. Yokogawa, 2013, Biomolecular NMR Assignments.

Complete assignment of the methionyl carbonyl carbon resonances in switch variant anti-dansyl antibodies labeled with [1-13C]methionine.

I. Shimada, Y. Arata, A. Odaka, 1991, Biochemistry.

An NMR method for the determination of protein-binding interfaces using dioxygen-induced spin-lattice relaxation enhancement.

I. Shimada, R. Prosser, P. Luchette, 2005, Journal of the American Chemical Society.

NMR analysis of the interaction between protein L and Ig light chains.

L. Björck, S. Forsén, I. Shimada, 1997, Journal of molecular biology.

Polypeptide chain fold of human transforming growth factor alpha analogous to those of mouse and human epidermal growth factors as studied by two-dimensional 1H NMR.

D. Kohda, I. Shimada, F. Inagaki, 1989, Biochemistry.

Crystallographic and lithium-6 and nitrogen-15 NMR studies of a chiral bidentate lithium amide. An effect of aggregation states on an enantioselective deprotonation reaction

K. Koga, I. Shimada, H. Kawasaki, 1992 .

Functional roles of Mg2+ binding sites in ion-dependent gating of a Mg2+ channel, MgtE, revealed by solution NMR

O. Nureki, M. Hattori, A. Maturana, 2018, eLife.

Structure of melittin bound to perdeuterated dodecylphosphocholine micelles as studied by two-dimensional NMR and distance geometry calculations

N. Go, I. Shimada, F. Inagaki, 1989 .

Stereoselective reactions. 26. Solution structures of chiral bidentate lithium amide in relation to the solvent-dependent enantioselectivities in deprotonation reaction

K. Koga, I. Shimada, H. Kawasaki, 1997 .

Structural basis for the inhibition of voltage-dependent K+ channel by gating modifier toxin

T. Nozaki, I. Shimada, M. Osawa, 2015, Scientific Reports.

Channel-forming Membrane Permeabilization by an Antibacterial Protein, Sapecin

Koh Takeuchi, Hideo Takahashi, Toshiyuki Kohno, 2004, Journal of Biological Chemistry.

Solution conformation of an antibacterial peptide, sarcotoxin IA, as determined by 1H-NMR.

I. Shimada, Y. Arata, S. Natori, 1993, European journal of biochemistry.

1H nuclear magnetic resonance study of the solution conformation of an antibacterial protein, sapecin

D. Kohda, I. Shimada, F. Inagaki, 1990, FEBS letters.

Identification and Characterization of a Second Chromophore of DNA Photolyase from Thermus thermophilus HB27*

Ichio Shimada, Seiki Kuramitsu, I. Shimada, 2005, Journal of Biological Chemistry.

Pairing of oligosaccharides in the Fc region of immunoglobulin G

I. Shimada, Y. Yamaguchi, K. Masuda, 2000, FEBS letters.

NMR assignments of the N-glycans of the Fc fragment of mouse immunoglobulin G2b glycoprotein

I. Shimada, Y. Yamaguchi, Rina Yogo, 2021, Biomolecular NMR Assignments.

Proteolytic fragmentation with high specificity of mouse immunoglobulin G. Mapping of proteolytic cleavage sites in the hinge region.

I. Shimada, Y. Yamaguchi, K. Masuda, 1995, Journal of immunological methods.

Post-translational modifications of immunoglobulin G: a mouse IgG variant that lacks the entire CH1 domain.

I. Shimada, K. Masuda, Y. Arata, 1999, Molecular immunology.

Structural Fingerprints of an Intact Monoclonal Antibody Acquired under Formulated Storage Conditions via 15N Direct Detection Nuclear Magnetic Resonance.

T. Torizawa, I. Shimada, K. Takeuchi, 2020, Journal of medicinal chemistry.

Model for the complex between protein G and an antibody Fc fragment in solution.

G. Roberts, L. Lian, I. Shimada, 1995, Structure.

Carbon-13 NMR study of switch variant anti-dansyl antibodies: antigen binding and domain-domain interactions.

I. Shimada, Y. Arata, A. Odaka, 1991, Biochemistry.

Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the μ-Opioid Receptor

I. Shimada, Kento Onishi, M. Inoue, 2015, Angewandte Chemie.

Functional dynamics of deuterated β2 -adrenergic receptor in lipid bilayers revealed by NMR spectroscopy.

I. Shimada, Shiho Suzuki, Takumi Ueda, 2014, Angewandte Chemie.

Efficacy of the β2-adrenergic receptor is determined by conformational equilibrium in the transmembrane region

Ichio Shimada, Hideki Tsujishita, I. Shimada, 2012, Nature Communications.

Comparative thermodynamic analyses of the Fv, Fab* and Fab and Fab fragments of anti‐dansyl mouse monoclonal antibody

A. Sarai, N. Shimba, I. Shimada, 1995 .

Structural Investigation of the Interaction between LolA and LolB Using NMR

I. Shimada, Hideo Takahashi, H. Tokuda, 2009, The Journal of Biological Chemistry.

Functional dynamics of proteins revealed by solution NMR.

I. Shimada, N. Nishida, K. Takeuchi, 2012, Current opinion in structural biology.

Nitrogen-detected TROSY yields comparable sensitivity to proton-detected TROSY for non-deuterated, large proteins under physiological salt conditions

Gerhard Wagner, I. Shimada, H. Arthanari, 2016, Journal of Biomolecular NMR.

NMR study of ligand release from asialoglycoprotein receptor under solution conditions in early endosomes

I. Shimada, Hideo Takahashi, Shozo Kanai, 2012, The FEBS journal.

The Affinity Maturation of Anti-4-hydroxy-3-nitrophenylacetyl Mouse Monoclonal Antibody

A. Sarai, I. Shimada, H. Torigoe, 1995, The Journal of Biological Chemistry.

Mechanism of hERG inhibition by gating-modifier toxin, APETx1, deduced by functional characterization

K. Ikeda, Y. Kubo, I. Shimada, 2020, bioRxiv.

Cross-saturation and transferred cross-saturation experiments

I. Shimada, N. Nishida, K. Takeuchi, 2009, Quarterly Reviews of Biophysics.

Mechanism of mRNA deadenylation: evidence for a molecular interplay between translation termination factor eRF3 and mRNA deadenylases.

Masanori Osawa, Toshiaki Katada, Ichio Shimada, 2007, Genes & development.

A receptor-binding peptide from human interleukin-6: isolation and a proton nuclear magnetic resonance study.

I. Shimada, Y. Arata, T. Ekida, 1992, Biochemical and biophysical research communications.

Proton nuclear magnetic resonance study of human interleukin 6: chemical modifications and partial spectral assignments for the aromatic residues.

I. Shimada, K. Yasukawa, H. Hanzawa, 1990, Biochimica et biophysica acta.

Endogenous Membrane Receptor Labeling by Reactive Cytokines and Growth Factors to Chase Their Dynamics in Live Cells

I. Shimada, I. Hamachi, M. Miyasaka, 2018, Chem.

Structural basis of the interaction between IgG and Fcgamma receptors.

C. Sautès-Fridman, W. Fridman, I. Shimada, 2000, Journal of molecular biology.

Real-Time In-Cell NMR Reveals the Intracellular Modulation of GTP-Bound Levels of RAS.

M. Ikura, I. Shimada, C. Marshall, 2020, Cell reports.

Activation of adenosine A2A receptor by lipids from docosahexaenoic acid revealed by NMR

I. Shimada, Takumi Ueda, Yutaka Kofuku, 2020, Science Advances.

Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties

K. Matsushima, M. Ohira, H. Nagase, 2020, Nature Communications.

Dynamic equilibrium on DNA defines transcriptional regulation of a multidrug binding transcriptional repressor, LmrR

I. Shimada, Misaki Imai, K. Takeuchi, 2017, Scientific Reports.

Dynamic multidrug recognition by multidrug transcriptional repressor LmrR

I. Shimada, Hideo Takahashi, Misaki Imai, 2014, Scientific Reports.

Structural mechanism underlying G protein family-specific regulation of G protein-gated inwardly rectifying potassium channel

I. Shimada, M. Osawa, Y. Toyama, 2019, Nature Communications.

Conformational multiplicity of the antibody combining site of a monoclonal antibody specific for a (6-4) photoproduct.

Y. Komatsu, T. Torizawa, O. Nikaido, 1999, Journal of molecular biology.

Mechanical force effect on the two-state equilibrium of the hyaluronan-binding domain of CD44 in cell rolling

I. Shimada, Shinji Ogino, Miho Suzuki, 2015, Proceedings of the National Academy of Sciences.

Conformational landscape alternations promote oncogenic activities of Ras-related C3 botulinum toxin substrate 1 as revealed by NMR

T. Katada, I. Shimada, Y. Toyama, 2019, Science Advances.

An NMR method to study protein-protein interactions.

I. Shimada, N. Nishida, 2012, Methods in molecular biology.

Two-state conformations in the hyaluronan-binding domain regulate CD44 adhesiveness under flow condition.

I. Shimada, Miho Suzuki, Shinji Ogino, 2010, Structure.

Dynamic equilibrium on DNA defines transcriptional regulation of a multidrug binding transcriptional repressor, LmrR

I. Shimada, Misaki Imai, K. Takeuchi, 2017, Scientific Reports.

Dynamic regulation of GDP binding to G proteins revealed by magnetic field-dependent NMR relaxation analyses

I. Shimada, M. Osawa, Y. Toyama, 2017, Nature Communications.

A multinuclear NMR study of the affinity maturation of anti-NP mouse monoclonal antibodies: comparison of antibody combining sites of primary response antibody N1G9 and secondary response antibody 3B62.

I. Shimada, Y. Arata, T. Nakayama, 1993, Biochemistry.

DNA-Binding Properties of the Antibody Specific for the Dewar Photoproduct of Thymidylyl-(3′′-5′′)-Thymidine

Hiroshi Morioka, Yasuo Komatsu, Ichio Shimada, 2006, Nucleosides, nucleotides & nucleic acids.

Conformational dynamics of complementarity-determining region H3 of an anti-dansyl Fv fragment in the presence of its hapten.

I. Shimada, Hideo Takahashi, M. Nakasako, 2005, Journal of molecular biology.

DNA binding mode of the Fab fragment of a monoclonal antibody specific for cyclobutane pyrimidine dimer.

Y. Komatsu, T. Torizawa, O. Nikaido, 2000, Nucleic acids research.

Structural characterization of mouse monoclonal antibody 13-1 against a porphyrin derivative: identification of a disulfide bond in CDR-H3 of Mab 13-1.

H. Yamaguchi, T. Torizawa, S. Akashi, 1997, Biochemical and biophysical research communications.

Crystallization and crystallographic studies on Fab fragments of anti-nitrophenol antibodies from primary and secondary immune responses

Y. Satow, I. Shimada, Y. Arata, 1996 .

Characterization of mouse switch variant antibodies by matrix-assisted laser desorption ionization mass spectrometry and electrospray ionization mass spectrometry

S. Akashi, I. Shimada, Y. Arata, 1996, Journal of the American Society for Mass Spectrometry.

Carbohydrate Binding Mechanism of the Macrophage Galactose-type C-type Lectin 1 Revealed by Saturation Transfer Experiments*

T. Irimura, I. Shimada, C. Moriyama, 2008, Journal of Biological Chemistry.

Characterization of the multimeric structure of poly(A)-binding protein on a poly(A) tail

S. Hoshino, I. Shimada, K. Mio, 2018, Scientific Reports.

Structural basis for platelet antiaggregation by angiotensin II type 1 receptor antagonist losartan (DuP-753) via glycoprotein VI.

K. Ono, I. Shimada, Hideo Takahashi, 2010, Journal of medicinal chemistry.

Forbidden Coherence Transfer of 19F Nuclei to Quantitatively Measure the Dynamics of a CF3-Containing Ligand in Receptor-Bound States

I. Shimada, K. Takeuchi, Yuji Tokunaga, 2017, Molecules.

Improvement of Ligand Affinity and Thermodynamic Properties by NMR-Based Evaluation of Local Dynamics and Surface Complementarity in the Receptor-Bound State.

I. Shimada, H. Hanzawa, K. Takeuchi, 2016, Angewandte Chemie.

Structural and Interaction Analysis of Glycoprotein VI-binding Peptide Selected from a Phage Display Library*

K. Ono, I. Shimada, Hideo Takahashi, 2009, Journal of Biological Chemistry.

Membrane perturbation by lipidated Atg8 underlies autophagosome biogenesis

S. Kageyama, M. Komatsu, I. Shimada, 2021, Nature Structural & Molecular Biology.

Membrane perturbation by lipidated Atg8 underlies autophagosome biogenesis

S. Kageyama, M. Komatsu, I. Shimada, 2021, Nature Structural & Molecular Biology.

Deuteration and selective labeling of alanine methyl groups of β2-adrenergic receptor expressed in a baculovirus-insect cell expression system

I. Shimada, T. Mizukoshi, H. Itoh, 2018, Journal of Biomolecular NMR.

Deuteration and selective labeling of alanine methyl groups of β2-adrenergic receptor expressed in a baculovirus-insect cell expression system

I. Shimada, T. Mizukoshi, H. Itoh, 2018, Journal of biomolecular NMR.

Phosphorylation-induced conformation of β2-adrenoceptor related to arrestin recruitment revealed by NMR

I. Shimada, T. Mizukoshi, Takumi Ueda, 2018, Nature Communications.

Conductance of P2X4 purinergic receptor is determined by conformational equilibrium in the transmembrane region

O. Nureki, M. Hattori, I. Shimada, 2016, Proceedings of the National Academy of Sciences.

Perdeuteration and methyl-selective 1H, 13C-labeling by using a Kluyveromyces lactis expression system

I. Shimada, Hideo Takahashi, T. Sugiki, 2013, Journal of Biomolecular NMR.

A gel-encapsulated bioreactor system for NMR studies of protein-protein interactions in living mammalian cells.

I. Shimada, Shinji Ogino, N. Nishida, 2013, Angewandte Chemie.

Functional Equilibrium of the KcsA Structure Revealed by NMR*

S. Oiki, I. Shimada, K. Takeuchi, 2012, The Journal of Biological Chemistry.

Utilization of paramagnetic relaxation enhancements for structural analysis of actin-binding proteins in complex with actin

I. Shimada, N. Nishida, T. Uyeda, 2016, Scientific Reports.

In situ structural biology using in-cell NMR.

I. Shimada, N. Nishida, Yutaka Ito, 2020, Biochimica et biophysica acta. General subjects.

Observation of NMR signals from proteins introduced into living mammalian cells by reversible membrane permeabilization using a pore-forming toxin, streptolysin O.

I. Shimada, Shinji Ogino, N. Nishida, 2009, Journal of the American Chemical Society.

NMR Study of Repair Mechanism of DNA Photolyase by FAD-induced Paramagnetic Relaxation Enhancement*

T. Torizawa, I. Shimada, S. Kuramitsu, 2004, Journal of Biological Chemistry.

Functional dynamics of cell surface membrane proteins.

I. Shimada, N. Nishida, K. Takeuchi, 2014, Journal of magnetic resonance.

Structural basis of the transition-state stabilization in antibody-catalyzed hydrolysis.

N. Shimba, I. Shimada, Hideo Takahashi, 2007, Journal of molecular biology.

Atypical Membrane-embedded Phosphatidylinositol 3,4-Bisphosphate (PI(3,4)P2)-binding Site on p47phox Phox Homology (PX) Domain Revealed by NMR*

I. Shimada, H. Sumimoto, Takumi Ueda, 2012, The Journal of Biological Chemistry.

Structural Basis for the Golgi Association by the Pleckstrin Homology Domain of the Ceramide Trafficking Protein (CERT)*

I. Shimada, Hideo Takahashi, T. Sugiki, 2012, The Journal of Biological Chemistry.

I. Shimada, Takumi Ueda, Yutaka Kofuku, 2019, Biophysical Reviews.

NMR Method for Characterizing Microsecond-to-Millisecond Chemical Exchanges Utilizing Differential Multiple-Quantum Relaxation in High Molecular Weight Proteins.

I. Shimada, M. Osawa, Y. Toyama, 2016, Journal of the American Chemical Society.

Structural basis of the collagen‐binding mode of discoidin domain receptor 2

N. Nomura, I. Shimada, O. Ichikawa, 2007, EMBO Journal.

Probing dynamics and conformational change of the GroEL-GroES complex by 13C NMR spectroscopy.

Masasuke Yoshida, I. Shimada, H. Fujikawa, 2006, Journal of biochemistry.

N-glycan structures of murine hippocampus serine protease, neuropsin, produced in Trichoplusia ni cells

T. Kishi, T. Hakoshima, I. Shimada, 1999, Glycoconjugate Journal.

N-glycan structures of a recombinant mouse soluble Fcγ receptor II

I. Shimada, Koichi Kato, K. Masuda, 1998, Glycoconjugate Journal.

Detailed structural analysis of asparagine-linked oligosaccharides of the nicotinic acetylcholine receptor from Torpedo californica.

I. Shimada, H. Nomoto, K. Hayashi, 1992, European journal of biochemistry.

Hexacyanochromate ion as a paramagnetic anion probe for active sites of enzymes.

I. Shimada, F. Inagaki, 1986, Journal of inorganic biochemistry.

Binding modes of inhibitors to ribonuclease T1 as studied by nuclear magnetic resonance.

I. Shimada, F. Inagaki, T. Miyazawa, 1985, Biochemistry.

Combinations with Other Methods

Y. Kurosawa, I. Shimada, F. Arisaka, 2000 .

Ligand-induced Structural Changes of the CD44 Hyaluronan-binding Domain Revealed by NMR*

Ichio Shimada, Masayoshi Sakakura, Masahiro Kajiwara, 2006, Journal of Biological Chemistry.

Segmental isotopic labeling of a 140 kDa dimeric multi-domain protein CheA from Escherichia coli by expressed protein ligation and protein trans-splicing

I. Shimada, Takumi Ueda, Hideo Iwaï, 2012, Journal of biomolecular NMR.

Phosphoinositide binding by the PH domain in ceramide transfer protein (CERT) is inhibited by hyperphosphorylation of an adjacent serine-repeat motif

T. Fujiwara, C. Kojima, I. Shimada, 2018, The Journal of Biological Chemistry.

DDR Structural Biology

I. Shimada, N. Nishida, 2016 .

Complete and rapid peptide and glycopeptide mapping of mouse monoclonal antibody by LC/MS/MS using ion trap mass spectrometry.

I. Shimada, Y. Arata, K. Hirayama, 1998, Analytical chemistry.

ATP-dependent modulation of MgtE in Mg2+ homeostasis

O. Nureki, M. Hattori, R. Ishitani, 2017, Nature Communications.

Suppression of Problematic Compound Oligomerization by Cosolubilization of Nondetergent Sulfobetaines

I. Shimada, Hideo Takahashi, H. Hanzawa, 2015, ChemMedChem.

An accurate pharmacophore mapping method by NMR spectroscopy.

Y. Fukunishi, I. Shimada, Hideo Takahashi, 2012, Angewandte Chemie.

Protein-ligand docking guided by ligand pharmacophore-mapping experiment by NMR.

Haruki Nakamura, Koh Takeuchi, Hideo Takahashi, 2011, Journal of molecular graphics & modelling.

NMR study of the interaction between the B domain of staphylococcal protein A and the Fc portion of immunoglobulin G.

I. Shimada, H. Gouda, H. Torigoe, 1998, Biochemistry.

ATP-dependent modulation of MgtE in Mg2+ homeostasis

O. Nureki, M. Hattori, R. Ishitani, 2017, Nature Communications.

Three-dimensional structures of the Fab fragment of murine N1G9 antibody from the primary immune response and of its complex with (4-hydroxy-3-nitrophenyl)acetate.

Y. Satow, I. Shimada, Y. Arata, 1995, Journal of molecular biology.

An NMR method for the determination of protein binding interfaces using TEMPOL-induced chemical shift perturbations.

I. Shimada, R. Prosser, Yuji Tokunaga, 2009, Biochimica et biophysica acta.

Quantitative Characterization of Tob Interactions Provides the Thermodynamic Basis for Translation Termination-coupled Deadenylase Regulation*

S. Hoshino, T. Katada, I. Shimada, 2010, The Journal of Biological Chemistry.

Solution Structure of ω-Grammotoxin SIA, A Gating Modifier of P/Q and N-type Ca2+ Channel

I. Shimada, Hideo Takahashi, J. Kim, 2002 .

Three-dimensional solution structure of the calcium channel antagonist omega-agatoxin IVA: consensus molecular folding of calcium channel blockers.

S. Konishi, I. Shimada, T. Kohno, 1995, Journal of molecular biology.

Activation mechanism of the μ-opioid receptor by an allosteric modulator

I. Shimada, Takumi Ueda, Yutaka Kofuku, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Dynamic domain arrangement of CheA-CheY complex regulates bacterial thermotaxis, as revealed by NMR

I. Shimada, Takumi Ueda, Hideo Iwaï, 2017, Scientific Reports.

Determination of Protonation and Deprotonation Forms and Tautomeric States of Histidine Residues in Large Proteins Using Nitrogen−Carbon J Couplings in Imidazole Ring

N. Shimba, I. Shimada, Hideo Takahashi, 1998 .

A Multinuclear NMR Study of the Active Site of an Endoglucanase from a Strain of Bacillus

I. Shimada, Hideo Takahashi, S. Ito, 1999, The Journal of Biological Chemistry.

Balanced Regulation of Redox Status of Intracellular Thioredoxin Revealed by in-Cell NMR.

I. Shimada, N. Nishida, S. Kubo, 2018, Journal of the American Chemical Society.

Structure of the Mouse Sex Peptide Pheromone ESP1 Reveals a Molecular Basis for Specific Binding to the Class C G-protein-coupled Vomeronasal Receptor*

I. Shimada, K. Touhara, K. Esaki, 2013, The Journal of Biological Chemistry.

Structure and receptor recognition of the sex pheromone ESP 1 1 Structure of the Mouse Sex Peptide Pheromone ESP 1 Reveals a Molecular Basis for Specific Binding to the Class-C G-Protein-Coupled Vomeronasal Receptor *

I. Shimada, K. Touhara, K. Esaki, 2013 .

Conformational equilibrium shift underlies altered K+ channel gating as revealed by NMR

I. Shimada, H. Itoh, M. Inoue, 2020, Nature Communications.

Phosphorylation-induced conformation of β2-adrenoceptor related to arrestin recruitment revealed by NMR

I. Shimada, T. Mizukoshi, Takumi Ueda, 2018, Nature Communications.

NMR Analyses of the Gβγ Binding and Conformational Rearrangements of the Cytoplasmic Pore of G Protein-activated Inwardly Rectifying Potassium Channel 1 (GIRK1)*

I. Shimada, K. Takeuchi, M. Osawa, 2010, The Journal of Biological Chemistry.

Accumulation of unique globo-series glycolipids in PC 12h pheochromocytoma cells.

Y. Kuroda, T. Miyatake, I. Shimada, 1989, Journal of Biological Chemistry.

Molecular basis of the high-affinity activation of type 1 ryanodine receptors by imperatoxin A.

D. H. Kim, I. Shimada, Hideo Takahashi, 2004, The Biochemical journal.

Spatial distribution of cytoplasmic domains of the Mg(2+)-transporter MgtE, in a solution lacking Mg(2+), revealed by paramagnetic relaxation enhancement.

O. Nureki, M. Hattori, R. Ishitani, 2012, Biochimica et biophysica acta.

I. Shimada, K. Takeuchi, Takumi Ueda, 2021, Membranes.

Utilization of Methyl Proton Resonances in Cross-Saturation Measurement for Determining the Interfaces of Large Protein–Protein Complexes

Y. Fukunishi, Haruki Nakamura, I. Shimada, 2006, Journal of biomolecular NMR.

Direct determination of the insulin-insulin receptor interface using transferred cross-saturation experiments.

N. Shimba, E. Suzuki, I. Shimada, 2010, Journal of medicinal chemistry.

Precise structural determination of weakly binding peptides by utilizing dihedral angle constraints

I. Shimada, Hideo Takahashi, Yumiko Mizukoshi, 2010, Journal of biomolecular NMR.

Backbone resonance assignments for the cytoplasmic regions of G protein-activated inwardly rectifying potassium channel 1 (GIRK1)

I. Shimada, T. Muramatsu, K. Takeuchi, 2009, Biomolecular NMR assignments.

NMR analyses of the interaction between CCR5 and its ligand using functional reconstitution of CCR5 in lipid bilayers.

K. Matsushima, I. Shimada, Takumi Ueda, 2010, Journal of the American Chemical Society.

I. Shimada, Takumi Ueda, Yutaka Kofuku, 2019, Biophysical Reviews.

Backbone resonance assignments for the ligand binding subunit of the histidine permease complex (HisJ) from Escherichia coli, under histidine-bound and unbound states

I. Shimada, M. Osawa, S. Igarashi, 2010, Biomolecular NMR assignments.

Development of a method for reconstruction of crowded NMR spectra from undersampled time-domain data

I. Shimada, K. Takeuchi, Takumi Ueda, 2015, Journal of biomolecular NMR.

Dynamical structure of the antibody combining site as studied by 1H-15N shift correlation NMR spectroscopy.

E. Suzuki, I. Shimada, Y. Arata, 1992, Biochemistry.

Determination of the interface of a large protein complex by transferred cross-saturation measurements.

I. Shimada, Hideo Takahashi, H. Terasawa, 2002, Journal of molecular biology.

NMR structure of the calponin homology domain of human IQGAP1 and its implications for the actin recognition mode

I. Shimada, Shinji Ogino, N. Nishida, 2010, Journal of biomolecular NMR.

Structural basis underlying the dual gate properties of KcsA

I. Shimada, K. Takeuchi, M. Osawa, 2010, Proceedings of the National Academy of Sciences.

Preparation of the Fv fragment from a short-chain mouse IgG2a anti-dansyl monoclonal antibody and use of selectively deuterated Fv analogues for two-dimensional 1H NMR analyses of the antigen-antibody interactions.

I. Shimada, Y. Arata, H. Takahashi, 1991, Biochemistry.

Decreased conformational stability in the oncogenic N92I mutant of Ras-related C3 botulinum toxin substrate 1

T. Katada, I. Shimada, Y. Toyama, 2019, Science Advances.

Letter to the Editor: Backbone 1H, 13C, and 15N resonance assignments of the anti-dansyl antibody Fv fragment

I. Shimada, Hideo Takahashi, Y. Arata, 2000, Journal of biomolecular NMR.

1H‐NMR investigation of the interaction between RNase T1 and a novel substrate analog, 2′‐deoxy‐2′‐fluoroguanylyl‐(3′–5′)uridine

M. Ikehara, I. Shimada, F. Inagaki, 1988, FEBS letters.

Nuclear magnetic resonance study on the microenvironments of histidine residues of ribonuclease T1 and carboxymethylated ribonuclease T1.

I. Shimada, F. Inagaki, Y. Kawano, 1981, Journal of biochemistry.

The pH-dependent structural variation of complementarity-determining region H3 in the crystal structures of the Fv fragment from an anti-dansyl monoclonal antibody.

N. Shimba, I. Shimada, M. Nakasako, 1999, Journal of molecular biology.

Structure-based approach to improve a small-molecule inhibitor by the use of a competitive peptide ligand.

K. Ono, I. Shimada, Hideo Takahashi, 2014, Angewandte Chemie.

Isotope-edited nuclear magnetic resonance study of Fv fragment of anti-dansyl mouse monoclonal antibody: recognition of the dansyl hapten.

I. Shimada, Y. Arata, H. Takahashi, 1992, Biochemistry.

Multinuclear NMR study of the structure of the Fv fragment of anti-dansyl mouse IgG2a antibody.

I. Shimada, Y. Arata, H. Takahashi, 1991, Biochemistry.

Backbone resonance assignments for the cytoplasmic region of the Mg2+ transporter MgtE in the Mg2+-unbound state

O. Nureki, M. Hattori, R. Ishitani, 2013, Biomolecular NMR assignments.

Transition protein 1 from boar late spermatid nuclei having DNA‐melting activity is a dimeric protein

I. Shimada, K. Akama, Hiroki Sato, 1998, Biochemistry and molecular biology international.

Real-time assay method of lipid extraction activity.

I. Shimada, Hideo Takahashi, T. Sugiki, 2010, Analytical biochemistry.

Disulfide mapping the voltage-sensing mechanism of a voltage-dependent potassium channel

T. Nozaki, I. Shimada, M. Osawa, 2016, Scientific Reports.

Evaluation of Drug Responses to Human β2AR Using Native Mass Spectrometry

M. Tajiri, S. Akashi, I. Shimada, 2023, ACS omega.

Optimization of 13C direct detection NMR methods

Alan S. Stern, Jeffrey C. Hoch, Volker Dötsch, 2004, Journal of biomolecular NMR.

Multi-state structure determination and dynamics analysis reveals a new ubiquitin-recognition mechanism in yeast ubiquitin C-terminal hydrolase

P. Güntert, T. Kigawa, I. Shimada, 2021, bioRxiv.

Affinity transfer to a human protein by CDR3 grafting of camelid VHH

I. Shimada, I. Ishida, Yoshitake Maeda, 2011, Protein science : a publication of the Protein Society.

Theoretical analyses of the transferred cross-saturation method.

I. Shimada, Takumi Ueda, M. Matsumoto, 2010, Journal of magnetic resonance.

Structural basis for the binding of the membrane‐proximal C‐terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT

D. Kohda, K. Matsushima, I. Shimada, 2014, The FEBS journal.

Convenient Peptide Mapping of Immunoglobulin G2b and Differentiation between Leucine and Isoleucine Residues by Mass Spectrometry Using 2H-Labeled Leucine

I. Shimada, Y. Yamaguchi, Y. Arata, 1998 .

Structural basis for the ethanol action on G-protein–activated inwardly rectifying potassium channel 1 revealed by NMR spectroscopy

I. Shimada, M. Osawa, Y. Toyama, 2018, Proceedings of the National Academy of Sciences.

High‐throughput screening of optimal solution conditions for structural biological studies by fluorescence correlation spectroscopy

I. Shimada, T. Sugiki, Takumi Ueda, 2009, Protein science : a publication of the Protein Society.

Structural Basis for Modulation of Gating Property of G Protein-gated Inwardly Rectifying Potassium Ion Channel (GIRK) by i/o-family G Protein α Subunit (Gαi/o)*

I. Shimada, M. Osawa, M. Yokogawa, 2012, The Journal of Biological Chemistry.

Observation of NMR signals from proteins introduced into living mammalian cells by reversible membrane permeabilization using a pore-forming toxin, streptolysin O.

I. Shimada, Shinji Ogino, N. Nishida, 2009, Journal of the American Chemical Society.

Identification and Characterization of the Slowly Exchanging pH-dependent Conformational Rearrangement in KcsA*

I. Shimada, K. Takeuchi, S. Kawano, 2007, Journal of Biological Chemistry.

NMR analyses of the interaction between CCR5 and its ligand using functional reconstitution of CCR5 in lipid bilayers.

K. Matsushima, I. Shimada, Takumi Ueda, 2010, Journal of the American Chemical Society.

Efficacy of the β2-adrenergic receptor is determined by conformational equilibrium in the transmembrane region

I. Shimada, Takumi Ueda, Yutaka Kofuku, 2012, Nature Communications.

I. Shimada, K. Takeuchi, Takumi Ueda, 2022, Nihon Kessho Gakkaishi.

Functional Equilibrium of Membrane Proteins by NMR

Ichio Shimada, I. Shimada, 2012 .

1H, 13C and 15N backbone resonance assignments of the hyaluronan-binding domain of CD44.

I. Shimada, Y. Yamaguchi, M. Miyasaka, 2004, Journal of Biomolecular NMR.

Affinity transfer to a human protein by CDR3 grafting of camelid VHH

I. Shimada, I. Ishida, Yoshitake Maeda, 2011, Protein science : a publication of the Protein Society.

Solution structure of hanatoxin1, a gating modifier of voltage-dependent K(+) channels: common surface features of gating modifier toxins.

I. Shimada, H. Takahashi, K. Sato, 2000, Journal of molecular biology.

A 1H-NMR study of the solution conformation of Icaria chemotactic peptide and its [Lys7] analog: effects on the physiological activity of a substitution of proline to lysine at position 7.

I. Shimada, C. Kitada, M. Fujino, 1990, Biochemical and biophysical research communications.

Solution Structure of v-Grammotoxin SIA , A Gating Modifier of P / Q and N-type Ca 2 1 Channel

I. Shimada, J. Kim, C. Lee, 2002 .

HNCA-TOCSY-CANH experiments with alternate 13C-12C labeling: a set of 3D experiment with unique supra-sequential information for mainchain resonance assignment

G. Wagner, I. Shimada, K. Takeuchi, 2011, Journal of biomolecular NMR.

Backbone and side-chain 1H, 15N and 13C resonance assignments of the microtubule-binding domain of yeast cytoplasmic dynein in the high and low-affinity states

I. Shimada, M. Kikkawa, N. Nishida, 2013, Biomolecular NMR Assignments.

Application of C-Terminal 7-Azabicyclo[2.2.1]heptane to Stabilize β-Strand-like Extended Conformation of a Neighboring α-Amino Acid.

I. Shimada, T. Ohwada, K. Takeuchi, 2018, The Journal of organic chemistry.

NMR Characterization of the Papain-like Protease from SARS-CoV-2 Identifies the Conformational Heterogeneity in Its Inhibitor-Binding Site.

I. Shimada, Yutaro Shiraishi, 2023, Journal of the American Chemical Society.

Structural Basis of the Interaction between Chemokine Stromal Cell-derived Factor-1/CXCL12 and Its G-protein-coupled Receptor CXCR4*

K. Matsushima, I. Shimada, Yoshitake Maeda, 2009, The Journal of Biological Chemistry.

The amino acids involved in the distinct carbohydrate specificities between macrophage galactose-type C-type lectins 1 and 2 (CD301a and b) of mice.

T. Irimura, J. Hirabayashi, I. Shimada, 2008, Biochimica et biophysica acta.