S. Hsu

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Biomolecular recognition mechanisms studied by NMR spectroscopy and MD simulations

S. Hsu, 2004 .

Green Fluorescent Protein issue Reviewing the latest developments in the science of green fluorescent protein

Sophie E. Jackson, Shang-Te Danny Hsu, S. Hsu, 2009 .

Structure and properties of a complex of α-synuclein and a single-domain camelid antibody.

C. Dobson, L. Wyns, E. Pardon, 2010, Journal of molecular biology.

The effect of Parkinson's-disease-associated mutations on the deubiquitinating enzyme UCH-L1.

Shang-Te Danny Hsu, Sophie E Jackson, S. Hsu, 2011, Journal of molecular biology.

Residue-Specific Annotation of Disorder-to-Order Transition and Cathepsin Inhibition of a Propeptide-Like Crammer from D. melanogaster

P. Lyu, S. Hsu, Chao-Sheng Cheng, 2013, PloS one.

Site-specific solid-state NMR studies of "trigger factor" in complex with the large ribosomal subunit 50S.

B. Reif, S. Hsu, E. Barbet-Massin, 2015, Angewandte Chemie.

Distinct shifts in site-specific glycosylation pattern of SARS-CoV-2 spike proteins associated with arising mutations in the D614G and Alpha variants

Chu-Wei Kuo, K. Khoo, S. Hsu, 2021, bioRxiv.

Lactose Binding Induces Opposing Dynamics Changes in Human Galectins Revealed by NMR-Based Hydrogen–Deuterium Exchange

S. Hsu, M. Ho, C. Chien, 2017, Molecules.

Protein knots provide mechano-resilience to an AAA+ protease-mediated proteolysis with profound ATP energy expenses.

S. Hsu, Yen-Ning Chen, M. K. Sriramoju, 2019, Biochimica et biophysica acta. Proteins and proteomics.

Topologically knotted deubiquitinases exhibit unprecedented mechanostability to withstand the proteolysis by an AAA+ protease

S. Hsu, Yen-Ning Chen, M. K. Sriramoju, 2018, Scientific Reports.

Random-Coil Behavior of Chemically Denatured Topologically Knotted Proteins Revealed by Small-Angle X-ray Scattering.

S. Hsu, Chih-Ting Huang, C. Chien, 2015, The journal of physical chemistry. B.

Comparative analysis of the folding dynamics and kinetics of an engineered knotted protein and its variants derived from HP0242 of Helicobacter pylori

P. Lyu, S. Hsu, S. Jackson, 2015, Journal of physics. Condensed matter : an Institute of Physics journal.

Targeting Protein Tyrosine Phosphatase PTP-PEST for Therapeutic Intervention in Acute Myocardial Infarction.

Yi-Yun Chen, S. Hsu, Y. Jou, 2019, Cardiovascular research.

NMR assignments of PI3-SH3 domain aided by protonless NMR spectroscopy

S. Hsu, 2014, Biomolecular NMR assignments.

Oxidation of catalytic cysteine of human deubiquitinase BAP1 triggers misfolding and aggregation in addition to functional loss.

S. Hsu, Sarita Puri, 2022, Biochemical and biophysical research communications.

Tumor suppressor BAP1 nuclear import is governed by transportin-1

Steven Lin, S. Hsu, Tian-Neng Li, 2022, The Journal of cell biology.

Untying a Knotted SPOUT RNA Methyltransferase by Circular Permutation Results in a Domain-Swapped Dimer.

P. Lyu, S. Hsu, I. Hu, 2019, Structure.

Untying a Protein Knot by Circular Permutation.

P. Lyu, S. Hsu, I. Hu, 2019 .

Folding Dynamics and Structural Basis of the Enzyme Mechanism of Ubiquitin C-Terminal Hydroylases

S. Hsu, 2016 .

Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2

S. Hsu, T. Hobman, Matthew S Macauley, 2021, Nature Chemical Biology.

Sialic acid-Dependent Binding and Viral Entry of SARS-CoV-2

S. Hsu, Matthew S Macauley, G. Boons, 2021, bioRxiv.

Dissecting the Structure–Activity Relationship of Galectin–Ligand Interactions

S. Hsu, Chun-Hung Lin, Hsien-Ya Lin, 2018, International journal of molecular sciences.

Familial Mutations and Post-translational Modifications of UCH-L1 in Parkinson’s Disease and Neurodegenerative Disorders

S. Hsu, Yun-Tzai Lee, Y. Lee, 2016, bioRxiv.

Biophysical and structural characterizations of the effects of mutations on the structure–activity relationships of SARS-CoV-2 spike protein

S. Hsu, Tzu-Jing Yang, P. Yu, 2022, Methods in Enzymology.

A booster dose of Delta × Omicron hybrid mRNA vaccine produced broadly neutralizing antibody against Omicron and other SARS-CoV-2 variants

S. Hsu, Po-Cheng Chiang, Y. Chou, 2022, Journal of biomedical science.

Nucleotide contributions to the structural integrity and DNA replication initiation activity of noncoding y RNA.

M. P. Kowalski, S. Balasubramanian, S. Hsu, 2014, Biochemistry.

Small molecule-mediated inhibition of translation by targeting a native RNA G-quadruplex.

S. Balasubramanian, Sunita Kumari, S. Hsu, 2010, Organic & biomolecular chemistry.

Nickel superoxide dismutase protects nitrogen fixation in Trichodesmium

Yun-Ru Chen, S. Hsu, J. Zehr, 2022, Limnology and Oceanography Letters.

Unfolding kinetics of human telomeric G-quadruplexes studied by NMR spectroscopy.

S. Hsu, Ming-hao Li, Zi-Fu Wang, 2014, The journal of physical chemistry. B.

Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.

E. Oldfield, A. H. Wang, S. Hsu, 2016, Angewandte Chemie.

In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM

K. Khoo, S. Hsu, Hui-Wen Chang, 2022, Nature Communications.

Comparative folding analyses of unknotted versus trefoil-knotted ornithine transcarbamylases suggest stabilizing effects of protein knots.

S. Hsu, Tzu-Jing Yang, M. K. Sriramoju, 2018, Biochemical and biophysical research communications.

The nisin–lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics

R. Kaptein, A. Bonvin, S. Hsu, 2004, Nature Structural &Molecular Biology.

Mapping the targeted membrane pore formation mechanism by solution NMR: the nisin Z and lipid II interaction in SDS micelles.

Robert Kaptein, R. Kaptein, A. Bonvin, 2002, Biochemistry.

A nonpeptidic reverse turn that promotes parallel sheet structure stabilized by C-H...O hydrogen bonds in a cyclopropane gamma-peptide.

S. Hsu, Fiona R. Truscott, Angus J. Morrison, 2008, Angewandte Chemie.

Diarylethynyl amides that recognize the parallel conformation of genomic promoter DNA G-quadruplexes.

S. Balasubramanian, S. Hsu, J. Dash, 2008, Journal of the American Chemical Society.

A small molecule that disrupts G-quadruplex DNA structure and enhances gene expression.

Shang-Te Danny Hsu, Shankar Balasubramanian, S. Balasubramanian, 2009, Journal of the American Chemical Society.

Supplementary material to "Structural polymorphism and substrate promiscuity of a ribosome-associated molecular chaperone"

S. Hsu, M. Ho, Y. Chiang, 2021, Magnetic Resonance.

A molten globule-to-ordered structure transition of Drosophila melanogaster crammer is required for its ability to inhibit cathepsin

P. Lyu, S. Hsu, Chao-Sheng Cheng, 2011, The Biochemical journal.

Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum

E. Oldfield, S. Hsu, T. Ko, 2014, Scientific Reports.

Solution structure and tandem DNA recognition of the C-terminal effector domain of PmrA from Klebsiella pneumoniae

S. Chou, S. Hsu, Shih-Hsiung Wu, 2013, Nucleic acids research.

Hydration of [d(CGC)r(aaa)d(TTTGCG)](2).

S. Chou, S. Hsu, J. W. Cheng, 2000, Journal of molecular biology.

The folding, stability and conformational dynamics of beta-barrel fluorescent proteins.

S. Hsu, S. Jackson, Georg Blaser, 2009, Chemical Society reviews.

A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics.

S. Balasubramanian, P. Várnai, S. Neidle, 2009, Journal of the American Chemical Society.

Folding Study of Venus Reveals a Strong Ion Dependence of Its Yellow Fluorescence under Mildly Acidic Conditions*

Lisa D. Cabrita, C. Dobson, S. Hsu, 2009, The Journal of Biological Chemistry.

The extremely slow‐exchanging core and acid‐denatured state of green fluorescent protein

J. Christodoulou, S. Hsu, S. Jackson, 2008, HFSP journal.

The Solution Structure of [d(CGC)r(amamam)d(TTTGCG)]2

S. Chou, S. Hsu, Jyawei Cheng, 2002, Journal of biomolecular NMR.

Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors

S. Hsu, Fu-Tong Liu, Chun-Hung Lin, 2016, Scientific Reports.

Probing ribosome-nascent chain complexes produced in vivo by NMR spectroscopy

Lisa D. Cabrita, C. Dobson, J. Christodoulou, 2009, Proceedings of the National Academy of Sciences.

Conformational transition of a hairpin structure to G-quadruplex within the WNT1 gene promoter.

S. Hsu, Ming-hao Li, Zi-Fu Wang, 2015, Journal of the American Chemical Society.

A novel transition pathway of ligand-induced topological conversion from hybrid forms to parallel forms of human telomeric G-quadruplexes

S. Hsu, Ming-hao Li, Zi-Fu Wang, 2016, Nucleic acids research.

Structural basis of sodium–potassium exchange of a human telomeric DNA quadruplex without topological conversion

S. Hsu, Ming-hao Li, Zi-Fu Wang, 2014, Nucleic acids research.

Soluble Siglec-14 glycan-recognition protein is generated by alternative splicing and suppresses myeloid inflammatory responses

S. Hsu, T. Angata, Po-Chun Huang, 2018, The Journal of Biological Chemistry.

Characterization and structural analyses of nonspecific lipid transfer protein 1 from mung bean.

P. Lyu, A. Bonvin, S. Hsu, 2005, Biochemistry.

Generation and Characterization of a Spike Glycoprotein Domain A-Specific Neutralizing Single-Chain Variable Fragment against Porcine Epidemic Diarrhea Virus

S. Hsu, Hui-Wen Chang, C. Chae, 2021, Vaccines.

Structure-activity relationships of B.1.617 and other SARS-CoV-2 spike variants

K. Khoo, S. Hsu, Yuan-Chih Chang, 2021, bioRxiv.

Cryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycans

K. Khoo, S. Hsu, T. Ko, 2020, Proceedings of the National Academy of Sciences.

Towards multiparametric fluorescent imaging of amyloid formation: studies of a YFP model of alpha-synuclein aggregation.

C. Dobson, C. Kaminski, C. Bertoncini, 2010, Journal of molecular biology.

1H, 15N and 13C assignments of the dimeric ribosome binding domain of trigger factor from Escherichia coli

C. Dobson, S. Hsu, 2009, Biomolecular NMR assignments.

Experimental free energy surfaces reveal the mechanisms of maintenance of protein solubility

Michele Vendruscolo, Fabrizio Chiti, Shang-Te Danny Hsu, 2011, Proceedings of the National Academy of Sciences.

A booster dose of Delta × Omicron hybrid mRNA vaccine produced broadly neutralizing antibody against Omicron and other SARS-CoV-2 variants

S. Hsu, Po-Cheng Chiang, Y. Chou, 2022, Journal of biomedical science.

The Solution Structure of the AppA BLUF Domain: Insight into the Mechanism of Light‐Induced Signaling

K. Hellingwerf, R. Kaptein, R. Boelens, 2006, Chembiochem : a European journal of chemical biology.

Evolution rescues folding of human immunodeficiency virus-1 envelope glycoprotein GP120 lacking a conserved disulfide bond.

Alexandre M J J Bonvin, Ben Berkhout, B. Berkhout, 2008, Molecular biology of the cell.

EVOLUTION RESCUES FOLDING OF HIV-1 ENVELOPE GLYCOPROTEIN GP 120 LACKING A CONSERVED DISULFIDE BOND Running head : A disulfide bond in β-barrel folding

A. Bonvin, R. Sanders, S. Hsu, 2008 .

Structure-guided antibody cocktail for prevention and treatment of COVID-19

J. Jan, S. Hsu, Yi-Ling Lin, 2021, PLoS pathogens.

D614G mutation in the SARS-CoV-2 spike protein enhances viral fitness by desensitizing it to temperature-dependent denaturation

S. Hsu, Yuan-Chih Chang, Tzu-Jing Yang, 2021, Journal of Biological Chemistry.

Effect of SARS-CoV-2 B.1.1.7 mutations on spike protein structure and function

S. Hsu, M. Ho, Yuan-Chih Chang, 2021, Nature Structural & Molecular Biology.

Impacts on the structure-function relationship of SARS-CoV-2 spike by B.1.1.7 mutations

S. Hsu, M. Ho, Yuan-Chih Chang, 2021, bioRxiv.

Structure, dynamics and folding of an immunoglobulin domain of the gelation factor (ABP-120) from Dictyostelium discoideum.

Lisa D. Cabrita, C. Dobson, J. Christodoulou, 2009, Journal of molecular biology.

Unraveling the folding mechanism of the smallest knotted protein, MJ0366.

Shang-Te Danny Hsu, S. Hsu, Szu-Yu Chen, 2015, The journal of physical chemistry. B.

Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/α‐synuclein complex by Hip

C. Dobson, C. Roodveldt, J. Christodoulou, 2009, The EMBO journal.

Crystal Structure of Vaccinia Viral A27 Protein Reveals a Novel Structure Critical for Its Function and Complex Formation with A26 Protein

A. H. Wang, S. Hsu, T. Ko, 2013, PLoS pathogens.

A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.

C. Dobson, L. Wyns, S. Muyldermans, 2013, The journal of physical chemistry. B.

Local Cooperativity in an Amyloidogenic State of Human Lysozyme Observed at Atomic Resolution

Christopher M. Dobson, Mireille Dumoulin, Xavier Salvatella, 2010, Journal of the American Chemical Society.

Entropic stabilization of a deubiquitinase provides conformational plasticity and slow unfolding kinetics beneficial for functioning on the proteasome

Shang-Te Danny Hsu, Meng-Ru Ho, S. Hsu, 2017, Scientific Reports.

Entropy calculation of HIV-1 Env gp120, its receptor CD4, and their complex: an analysis of configurational entropy changes upon complexation.

Wilfred F van Gunsteren, Alexandre M J J Bonvin, Christine Peter, 2005, Biophysical journal.

Accurate random coil chemical shifts from an analysis of loop regions in native states of proteins.

Michele Vendruscolo, Wim Vranken, Andrea Cavalli, 2009, Journal of the American Chemical Society.

A Multivalent Marine Lectin from Crenomytilus grayanus Possesses Anti-cancer Activity through Recognizing Globotriose Gb3.

Chung-Yi Wu, S. Hsu, J. Liao, 2016, Journal of the American Chemical Society.

The catalytic activity of TCPTP is auto-regulated by its intrinsically disordered tail and activated by Integrin alpha-1

Yi-Yun Chen, S. Hsu, W. Peti, 2022, Nature Communications.

The catalytic activity of TCPTP is auto-regulated by its intrinsically disordered tail and activated by Integrin alpha-1

Yi-Yun Chen, S. Hsu, W. Peti, 2022, Nature communications.

Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy

Shang-Te Danny Hsu, Christopher M Dobson, Lisa D. Cabrita, 2007, Proceedings of the National Academy of Sciences.

NMR assignments of PI3-SH3 domain aided by protonless NMR spectroscopy

S. Hsu, 2013, Biomolecular NMR Assignments.

1H, 13C and 15N resonance assignments of human muscle acylphosphatase

C. Dobson, M. Vendruscolo, F. Chiti, 2012, Biomolecular NMR assignments.

Tying up the Loose Ends: A Mathematically Knotted Protein

A. Goldman, S. Hsu, I. Tascón, 2021, Frontiers in Chemistry.

1H, 15N and 13C assignments of domain 5 of Dictyostelium discoideum gelation factor (ABP-120) in its native and 8M urea-denatured states

Lisa D. Cabrita, C. Dobson, J. Christodoulou, 2009, Biomolecular NMR assignments.

Direct Visualization of a 26 kDa Protein by Cryo-Electron Microscopy Aided by a Small Scaffold Protein.

S. Hsu, M. Ho, Kuen-Phon Wu, 2021, Biochemistry.

Structure and Catalytic Mechanism of a Glycoside Hydrolase Family-127 β-L-Arabinofuranosidase (HypBA1)

Zhen Zhu, S. Hsu, T. Ko, 2014 .

NMR Study of Mersacidin and Lipid II Interaction in Dodecylphosphocholine Micelles

R. Kaptein, A. Bonvin, H. Sahl, 2003, The Journal of Biological Chemistry.

Familial Mutations and Post-translational Modifications of UCH-L1 in Parkinson’s Disease and Neurodegenerative Disorders

S. Hsu, Y. Lee, 2015, bioRxiv.

BARD1 is an ATPase activating protein for OLA1.

Yi-Yun Chen, Wei-Ting Huang, S. Hsu, 2022, Biochimica et biophysica acta. General subjects.

Converging experimental and computational views of the knotting mechanism of a small knotted protein.

C. Camilloni, S. Hsu, C. Paissoni, 2021, Biophysical journal.

Topologically knotted deubiquitinases exhibit unprecedented mechanostability to withstand the proteolysis by an AAA+ protease

S. Hsu, Yen-Ning Chen, M. K. Sriramoju, 2018, Scientific Reports.

How Native and Non-Native Cations Bind and Modulate the Properties of GTP/ATP.

C. Lim, S. Hsu, Cédric Grauffel, 2018, Journal of Chemical Theory and Computation.

Untying a Protein Knot by Circular Permutation.

Ping-Chiang Lyu, Shang-Te Danny Hsu, I-Chen Hu, 2019, Journal of molecular biology.

Protein knotting through concatenation significantly reduces folding stability

S. Hsu, 2016, Scientific Reports.

Folding analysis of the most complex Stevedore’s protein knot

Shang-Te Danny Hsu, S. Hsu, Szu-Yu Chen, 2016, Scientific Reports.

The Knotted Protein UCH-L1 Exhibits Partially Unfolded Forms under Native Conditions that Share Common Structural Features with Its Kinetic Folding Intermediates.

Shang-Te Danny Hsu, Sophie E Jackson, Hongyu Zhang, 2016, Journal of molecular biology.

Backbone NMR assignments of a topologically knotted protein in urea-denatured state

S. Hsu, Anna L. Mallam, S. Jackson, 2014, Biomolecular NMR assignments.

Backbone 1H, 13C and 15N assignments of YibK and avariant containing a unique cysteine residue at C-terminus in 8 M urea-denatured states [corrected].

S. Hsu, Anna L. Mallam, S. Jackson, 2014, Biomolecular NMR assignments.

Backbone NMR assignments of a topologically knotted protein in urea-denatured state

S. Hsu, Anna L. Mallam, S. Jackson, 2013, Biomolecular NMR Assignments.

Backbone NMR assignments of a topologically knotted protein in urea-denatured state

S. Hsu, Anna L. Mallam, S. Jackson, 2013, Biomolecular NMR Assignments.

1H, 15N and 13C assignments of yellow fluorescent protein (YFP) Venus

Lisa D. Cabrita, C. Dobson, S. Hsu, 2009, Biomolecular NMR assignments.

Self-Assembly of MinE on the Membrane Underlies Formation of the MinE Ring to Sustain Function of the Escherichia coli Min System*

M. Zheng, S. Hsu, L. Rothfield, 2014, The Journal of Biological Chemistry.

A High-Throughput Interbacterial Competition Screen Identifies ClpAP in Enhancing Recipient Susceptibility to Type VI Secretion System-Mediated Attack by Agrobacterium tumefaciens

S. Hsu, Manda Yu, E. Lai, 2020, Frontiers in Microbiology.

1H, 13C and 15N assignments of a camelid nanobody directed against human α-synuclein

C. Dobson, L. Wyns, E. Pardon, 2009, Biomolecular NMR assignments.

High Density of N- and O-Glycosylation Shields and Defines the Structural Dynamics of the Intrinsically Disordered Ectodomain of Receptor-type Protein Tyrosine Phosphatase Alpha

Chu-Wei Kuo, K. Khoo, S. Hsu, 2023, JACS Au.

Use of protonless NMR spectroscopy to alleviate the loss of information resulting from exchange-broadening.

Christopher M. Dobson, Carlos W. Bertoncini, Shang-Te Danny Hsu, 2009, Journal of the American Chemical Society.

Transient tertiary structure formation within the ribosome exit port.

Michele Vendruscolo, Shang-Te Danny Hsu, Christopher M Dobson, 2010, Journal of the American Chemical Society.

An N‐glycopeptide MS/MS data analysis workflow leveraging two complementary glycoproteomic software tools for more confident identification and assignments

Chu-Wei Kuo, K. Khoo, S. Hsu, 2023, Proteomics.

The solution structure of [d(CGC)r(aaa)d(TTTGCG)](2): hybrid junctions flanked by DNA duplexes.

S. Hsu, J. W. Cheng, M. Chou, 2000, Nucleic acids research.

1H, 13C and 15N assignments of a camelid nanobody directed against human α-synuclein

C. Dobson, L. Wyns, E. Pardon, 2009, Biomolecular NMR assignments.

Probing ribosome-nascent chain complexes produced in vivo by NMR spectroscopy

Lisa D. Cabrita, C. Dobson, J. Christodoulou, 2009, Proceedings of the National Academy of Sciences.

, Min System Escherichia coli Sustain Function of the Underlies Formation of the MinE Ring to Self-Assembly of MinE on the Membrane

M. Zheng, S. Hsu, L. Rothfield, 2014 .

Structure, dynamics and folding of an immunoglobulin domain of the gelation factor (ABP-120) from Dictyostelium discoideum.

Lisa D. Cabrita, C. Dobson, J. Christodoulou, 2009, Journal of molecular biology.

Key Residues of Outer Membrane Protein OprI Involved in Hexamer Formation and Bacterial Susceptibility to Cationic Antimicrobial Peptides

S. Hsu, Y. Liao, Ting-Wei Chang, 2015, Antimicrobial Agents and Chemotherapy.

Untying a Knotted SPOUT RNA Methyltransferase by Circular Permutation Results in a Domain-Swapped Dimer.

P. Lyu, S. Hsu, I. Hu, 2019, Structure.

Comparative analysis of the folding dynamics and kinetics of an engineered knotted protein and its variants derived from HP0242 of Helicobacter pylori

P. Lyu, S. Hsu, S. Jackson, 2015, Journal of physics. Condensed matter : an Institute of Physics journal.

Crystal structure of circular-permutated YibK methyltransferase from Haemophilus influenzae

P. Lyu, S. Hsu, I. Hu, 2019 .

Elucidation of the folding pathway of a circular permutant of topologically knotted YbeA by tryptophan substitutions.

P. Lyu, S. Hsu, I. Hu, 2023, Biochemical and biophysical research communications.

A Natively Monomeric Deubiquitinase UCH-L1 Forms Highly Dynamic but Defined Metastable Oligomeric Folding Intermediates.

S. Hsu, Y. Lee, 2018, The journal of physical chemistry letters.

Atomic insight into the CD4 binding‐induced conformational changes in HIV‐1 gp120

A. Bonvin, S. Hsu, 2004, Proteins.

NMR assignments of the C-terminal domain of human galectin-8

S. Hsu, Chun-Hung Lin, C. Chien, 2015, Biomolecular NMR Assignments.