G. Spraggon

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X‐Ray Crystallography for Biotherapeutics

G. Spraggon, 2014 .

Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline

Adam Godzik, Chittibabu Guda, Peter G Schultz, 2002, Proceedings of the National Academy of Sciences of the United States of America.

An approach to rapid protein crystallization using nanodroplets

Earl W. Cornell, Peter G. Schultz, D. Scheibe, 2002 .

Structural basis of murein peptide specificity of a gamma-D-glutamyl-l-diamino acid endopeptidase.

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2009, Structure.

The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, l-tryptophan

C. Yanofsky, G. Spraggon, M. Yee, 2001, Proceedings of the National Academy of Sciences of the United States of America.

A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase.

Bao Q. Pham, Susan S. Taylor, N. Xuong, 2006, Molecular cell.

Structure of a copper-mediated base pair in DNA.

P. Schultz, S. Atwell, E. Meggers, 2001, Journal of the American Chemical Society.

On the use of DXMS to produce more crystallizable proteins: Structures of the T. maritima proteins TM0160 and TM1171

Virgil L. Woods, I. Wilson, G. Spraggon, 2004, Protein science : a publication of the Protein Society.

An evolved aminoacyl-tRNA synthetase with atypical polysubstrate specificity.

P. Schultz, G. Spraggon, D. Young, 2011, Biochemistry.

Crystal structure of TM1367 from Thermotoga maritima at 1.90 Å resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2006, Proteins.

Crystal Structure of a Two-Subunit TrkA Octameric Gating Ring Assembly

Mitchell D. Miller, I. Wilson, G. Spraggon, 2015, PloS one.

Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197

R. Rappuoli, M. Bottomley, G. Spraggon, 2012, Proceedings of the National Academy of Sciences.

A general strategy for creating "inactive-conformation" abl inhibitors.

Taebo Sim, Yi Liu, Yongping Xie, 2006, Chemistry & biology.

Crystal structure of an α/β serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 Å resolution

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2004 .

A neural net approach to the automated analysis of crystallization trials

J. Priestle, G. Spraggon, S. Lesley, 2002 .

Crystal structure of thy1, a thymidylate synthase complementing protein from Thermotoga maritima at 2.25 Å resolution

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2002, Proteins.

Crystal structure of a PIN (PilT N‐terminus) domain (AF0591) from Archaeoglobus fulgidus at 1.90 Å resolution

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2004, Proteins.

Crystal structure of an iron‐containing 1,3‐propanediol dehydrogenase (TM0920) from Thermotoga maritima at 1.3 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2003, Proteins.

Comparative structural analysis of a novel glutathioneS‐transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2006, Proteins.

Crystal structure of an Apo mRNA decapping enzyme (DcpS) from Mouse at 1.83 Å resolution

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2005, Proteins.

Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

Susan E. Cellitti, P. Niyomrattanakit, J. Shaffer, 2012, Structure.

Tuning a Protein Labeling Reaction to Achieve Highly Site-Selective Lysine Conjugation.

Susan E. Cellitti, G. Spraggon, A. Brock, 2018 .

Human fibrinogen: anticipating a 3‐dimensional structure

R. Doolittle, S. Everse, G. Spraggon, 1996, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Crystal structure of a transcription regulator (TM1602) from Thermotoga maritima at 2.3 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2007, Proteins.

Crystal structure of TM1030 from Thermotoga maritima at 2.3 Å resolution reveals molecular details of its transcription repressor function

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2007, Proteins: Structure, Function, and Bioinformatics.

Crystal structure of an ORFan protein (TM1622) from Thermotoga maritima at 1.75 Å resolution reveals a fold similar to the Ran‐binding protein Mog1p

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2006, Proteins.

Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2006, Proteins.

Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide.

R. Doolittle, S. Everse, Zhe Yang, 2002, Biochemistry.

Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin

R. Doolittle, S. Everse, G. Spraggon, 1997, Nature.

Crystal structure of an alanine‐glyoxylate aminotransferase from Anabaena sp. at 1.70 Å resolution reveals a noncovalently linked PLP cofactor

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2005, Proteins.

Crystal structure of a zinc‐containing glycerol dehydrogenase (TM0423) from Thermotoga maritima at 1.5 Å resolution

Adam Godzik, Slawomir K. Grzechnik, Chittibabu Guda, 2002, Proteins.

An evolved aminoacyl-tRNA synthetase with atypical polysubstrate specificity.

P. Schultz, G. Spraggon, D. Young, 2011, Biochemistry.

Secreted PCSK9 promotes LDL receptor degradation independently of proteolytic activity.

Jennifer L. Harris, J. Trauger, G. Spraggon, 2007, The Biochemical journal.

Photoinduced Rearrangement of Dienones and Santonin Rerouted by Amines.

G. Spraggon, Zhipeng Zhang, P. Alper, 2018, Angewandte Chemie.

Identification of a PCSK9-LDLR disruptor peptide with in vivo function.

V. Subramanian, G. Spraggon, A. Koch, 2021, Cell chemical biology.

Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe.

P. Schultz, G. Spraggon, Feng Wang, 2009, Journal of the American Chemical Society.

Crystal structure of fragment double-D from human fibrin with two different bound ligands.

R. Doolittle, S. Everse, G. Spraggon, 1998, Biochemistry.

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

R. Rappuoli, V. Masignani, M. Bottomley, 2014, Proceedings of the National Academy of Sciences.

Crystal structure of phosphoribosylformyl‐glycinamidine synthase II, PurS subunit (TM1244) from Thermotoga maritima at 1.90 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2006, Proteins.

Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus pneumoniae Pilus

R. Rappuoli, Eric Koesema, V. Masignani, 2010, PloS one.

A general strategy for creating

M. Warmuth, N. Gray, G. Spraggon, 2006 .

Importance of model size in quantum mechanical studies of DNA intercalation

Steven E. Wheeler, Laura J. Kingsley, G. Spraggon, 2019, J. Comput. Chem..

In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy.

Susan E. Cellitti, J. Caldwell, P. Schultz, 2008, Journal of the American Chemical Society.

26A. Crystal structure of a recombinant ??EC domain from human fibrinogen-420

R. Doolittle, S. Everse, G. Spraggon, 1998 .

The compact domain conformation of human Glu-plasminogen in solution.

C. Ponting, C. Blake, G. Spraggon, 1992, Biochimica et biophysica acta.

Characterization and optimization of selective, nonpeptidic inhibitors of cathepsin S with an unprecedented binding mode.

G. Spraggon, S. Lesley, J. Ellman, 2007, Journal of medicinal chemistry.

Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs.

Peter G Schultz, Shigeo Matsuda, Floyd E Romesberg, 2007, Journal of the American Chemical Society.

Synthesis and evaluation of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 3: heterocyclic P3.

Jun Li, Glen Spraggon, Tove Tuntland, 2006, Bioorganic & medicinal chemistry letters.

Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology.

Laura J. Kingsley, S. Bender, M. Vaillancourt, 2021, Journal of medicinal chemistry.

The crystal structure of the catalytic domain of human urokinase-type plasminogen activator.

C. Ponting, C. Dobson, D. Stuart, 1995, Structure.

Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

Glen Spraggon, Badry Bursulaya, Todd Groessl, 2016, Nature.

Human fibrmogen: anticipating a 3-dimensional

S. Everse, G. Spraggon, Russell F. DOOLrFrLE, 1996 .

Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

Susan E. Cellitti, P. Niyomrattanakit, J. Shaffer, 2013, Structure.

Discovery of (R,E)-N-(7-Chloro-1-(1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide (EGF816), a Novel, Potent, and WT Sparing Covalent Inhibitor of Oncogenic (L858R, ex19del) and Resistant (T790M) EGFR Mutants for the Treatment of EGFR Mutant Non-Small-Ce

Chun Xing Li, S. Bender, G. Spraggon, 2016, Journal of medicinal chemistry.

Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

Susan E. Cellitti, P. Niyomrattanakit, J. Shaffer, 2012, Structure.

Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus.

M. Schirle, E. Mcwhinnie, M. Bottomley, 2013, The Biochemical journal.

Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases

F. Supek, D. Caridha, Yen-Liang Chen, 2020, Journal of medicinal chemistry.

Crystallization and X-ray diffraction study of recombinant platelet-derived endothelial cell growth factor.

C. Ponting, D. Stuart, G. Spraggon, 1993, Journal of Molecular Biology.

High-throughput proteomics

Scott A. Lesley, Marc Nasoff, Andreas Kreusch, 2001, SPIE BiOS.

Human platelet‐derived endothelial cell growth factor is homologous to Escherichia coli thymidine phosphorylase

C. Ponting, G. Spraggon, D. Sleep, 1992, Protein science : a publication of the Protein Society.

Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.

Glen Spraggon, Scott A Lesley, Nanxin Li, 2010, The Biochemical journal.

Evolution of vertebrate fibrin formation and the process of its dissolution.

R. Doolittle, S. Everse, G. Spraggon, 1997, Ciba Foundation symposium.

Crystal structure of uronate isomerase (TM0064) from Thermotoga maritima at 2.85 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2003, Proteins.

The crystal structure of anthranilate phosphoribosyltransferase from the enterobacterium Pectobacterium carotovorum

N. Xuong, Madhusudan, G. Spraggon, 2002, FEBS letters.

FdeC, a Novel Broadly Conserved Escherichia coli Adhesin Eliciting Protection against Urinary Tract Infections

R. Rappuoli, G. Spraggon, M. Pizza, 2012, mBio.

A Three-Dimensional Consideration of Variant Human Fibrinogens

S. Everse, G. Spraggon, R. Doolittle, 1998, Thrombosis and Haemostasis.

Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations

Aaron Shipway, Jennifer L. Harris, G. Spraggon, 2009, Protein science : a publication of the Protein Society.

Three-dimensional structural studies on fragments of fibrinogen and fibrin.

R. Doolittle, S. Everse, G. Spraggon, 1998, Current opinion in structural biology.

Crystal Structures of Fragments D and Double-D from Fibrinogen and Fibrin

R. Doolittle, S. Everse, G. Spraggon, 1999, Thrombosis and Haemostasis.

Supplemental Data Structural Basis of Murein Peptide Specificity of a γ-D-Glutamyl-L-Diamino Acid Endopeptidase

Linda, Slawomir K. Grzechnik, Mitchell D. Miller, 2009 .

Crystal structure of human Pus10, a novel pseudouridine synthase.

Glen Spraggon, Andreas Kreusch, G. Spraggon, 2007, Journal of molecular biology.

Biochemical characterization of respiratory syncytial virus RNA-dependent RNA polymerase complex.

G. Spraggon, M. Hekmatnejad, M. Didonato, 2020, ACS infectious diseases.

Crystal structure of the human neuropilin-1 b1 domain.

G. Spraggon, A. Kreusch, D. Mcmullan, 2003, Structure.

Crystal structure of an orphan protein (TM0875) from Thermotoga maritima at 2.00‐Å resolution reveals a new fold

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 1.60 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Shotgun crystallization strategy for structural genomics: an optimized two-tiered crystallization screen against the Thermotoga maritima proteome.

Slawomir K. Grzechnik, Rebecca Page, Peter Kuhn, 2003, Acta crystallographica. Section D, Biological crystallography.

Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.

R. Doolittle, S. Everse, G. Spraggon, 1999, Biochemistry.

Crystal structure of an aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.

Tao Jiang, Bo Liu, Glen Spraggon, 2017, ACS medicinal chemistry letters.

The structures of the neurotrophin 4 homodimer and the brain‐derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk‐binding site

D. Stuart, R. Robinson, E. Jones, 1999, Protein science : a publication of the Protein Society.

Structural plasticity of an aminoacyl-tRNA synthetase active site.

P. Schultz, G. Spraggon, J. Graziano, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Site‐Specific Dual Labeling of Proteins by Using Small Orthogonal Tags at Neutral pH

G. Spraggon, A. Brock, K. Ng, 2014, Chembiochem : a European journal of chemical biology.

Crystal structure of the type III effector AvrB from Pseudomonas syringae.

F. Katagiri, P. Luginbühl, G. Spraggon, 2004, Structure.

Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 Å resolution reveals a new fold

Mitchell D. Miller, A. Godzik, K. Hodgson, 2005, Proteins.

Crystal structure of gamma-glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.0 A resolution.

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of γ‐glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.0 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2003 .

The self-inhibited structure of full-length PCSK9 at 1.9 Å reveals structural homology with resistin within the C-terminal domain

Jennifer L. Harris, G. Spraggon, S. Lesley, 2007, Proceedings of the National Academy of Sciences.

The site-specific incorporation of p-iodo-L-phenylalanine into proteins for structure determination

P. Schultz, J. Xie, Lei Wang, 2004, Nature Biotechnology.

Envelope skeletonization as a means to determine monomer masks and non-crystallographic symmetry relationships: application in the solution of the structure of fibrinogen fragment D.

G. Spraggon, 1999, Acta crystallographica. Section D, Biological crystallography.

Crystal structure of a single‐stranded DNA‐binding protein (TM0604) from Thermotoga maritima at 2.60 Å resolution

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2006, Proteins.

Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design.

H. M. Petrassi, Aaron Shipway, Jennifer L. Harris, 2008, Bioorganic & Medicinal Chemistry Letters.

Crystal structure of S‐adenosylmethionine:tRNA ribosyltransferase‐isomerase (QueA) from Thermotoga maritima at 2.0 Å resolution reveals a new fold

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2005, Proteins.

Crystal structure of an indigoidine synthase A (IndA)‐like protein (TM1464) from Thermotoga maritima at 1.90 Å resolution reveals a new fold

Mitchell D. Miller, A. Godzik, A. Deacon, 2005, Proteins.

Crystal structure of a formiminotetrahydrofolate cyclodeaminase (TM1560) from Thermotoga maritima at 2.80 Å resolution reveals a new fold

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2005, Proteins: Structure, Function, and Bioinformatics.

Crystal structure of a tandem cystathionine‐β‐synthase (CBS) domain protein (TM0935) from Thermotoga maritima at 1.87 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of a novel Thermotoga maritima enzyme (TM1112) from the cupin family at 1.83 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins: Structure, Function, and Bioinformatics.

Crystal structure of a novel manganese‐containing cupin (TM1459) from Thermotoga maritima at 1.65 Å resolution

Mitchell D. Miller, A. Godzik, A. Deacon, 2004, Proteins.

Crystal structure of a putative oxalate decarboxylase (TM1287) from Thermotoga maritima at 1.95 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of O‐acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.8 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins: Structure, Function, and Bioinformatics.

Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins: Structure, Function, and Bioinformatics.

Crystal structure of a ribose‐5‐phosphate isomerase RpiB (TM1080) from Thermotoga maritima at 1.90 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of an Udp‐n‐acetylmuramate‐alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 Å resolution

Mitchell D. Miller, A. Godzik, A. Deacon, 2004, Proteins.

Crystal structure of a type II quinolic acid phosphoribosyltransferase (TM1645) from Thermotoga maritima at 2.50 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of a phosphoribosylaminoimidazole mutase PurE (TM0446) from Thermotoga maritima at 1.77‐Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of an HEPN domain protein (TM0613) from Thermotoga maritima at 1.75 Å resolution

Mitchell D. Miller, A. Godzik, A. Deacon, 2004, Proteins.

Crystal structure of a putative glutamine amido transferase (TM1158) from Thermotoga maritima at 1.7 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of a putative PII‐like signaling protein (TM0021) from Thermotoga maritima at 2.5 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Discovery of small molecules that target a tertiary-structured RNA

G. F. Joyce, J. Shaffer, G. Spraggon, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Structural and functional characterization of the Staphylococcus aureus virulence factor and vaccine candidate FhuD2.

Fabio Bagnoli, Glen Spraggon, Guido Grandi, 2013, The Biochemical journal.

Structural and functional characterization of the Staphylococcus aureus virulence factor and vaccine candidate FhuD 2

M. Bottomley, G. Spraggon, G. Grandi, 2012 .

Integration of Inositol Phosphate Signaling Pathways via Human ITPK1*

G. Spraggon, S. Lesley, David H. Jones, 2007, Journal of Biological Chemistry.

Estimation of Hydrogen-Exchange Protection Factors from MD Simulation Based on Amide Hydrogen Bonding Analysis

Scott A. Lesley, Glen Spraggon, In-Hee Park, 2015, J. Chem. Inf. Model..

Computational analysis of crystallization trials.

Glen Spraggon, Scott A Lesley, Andreas Kreusch, 2002, Acta crystallographica. Section D, Biological crystallography.

Identification of selective, nonpeptidic nitrile inhibitors of cathepsin s using the substrate activity screening method.

Scott Lesley, Glen Spraggon, G. Spraggon, 2006, Journal of medicinal chemistry.

Development of a virtual reality platform for effective communication of structural data in drug discovery.

Laura J Kingsley, Vincent Brunet, Gerald Lelais, 2019, Journal of molecular graphics & modelling.

Tuning a Protein‐Labeling Reaction to Achieve Highly Site Selective Lysine Conjugation

Susan E. Cellitti, G. Spraggon, A. Brock, 2018, Chembiochem : a European journal of chemical biology.

Image-based crystal detection: a machine-learning approach

Yoav Freund, Roy Liu, Glen Spraggon, 2008, Acta crystallographica. Section D, Biological crystallography.

Structural characterization of a p-acetylphenylalanyl aminoacyl-tRNA synthetase.

P. Schultz, G. Spraggon, J. Graziano, 2005, Journal of the American Chemical Society.

Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody

M. Bottomley, G. Spraggon, E. Malito, 2018, PloS one.

Structure analysis of peptide deformylases from Streptococcus pneumoniae, Staphylococcus aureus, Thermotoga maritima and Pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase.

G. Spraggon, S. Lesley, A. Kreusch, 2003, Journal of molecular biology.

Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers.

Jun Li, Glen Spraggon, Tove Tuntland, 2006, Bioorganic & medicinal chemistry letters.

Structural insights into enzyme regulation for inositol 1,4,5-trisphosphate 3-kinase B.

Glen Spraggon, Scott A Lesley, M. Cooke, 2005, Biochemistry.

Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 Å resolution reveals a new fold

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2006, Proteins.

Crystal structure of 2‐keto‐3‐deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2008, Proteins: Structure, Function, and Bioinformatics.

Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.

Sungjoon Kim, Nanxin Li, Jennifer L. Harris, 2010, The Biochemical journal.

Crystal structure of a putative NADPH‐dependent oxidoreductase (GI: 18204011) from mouse at 2.10 Å resolution

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2004, Proteins.

Crystal structure of 2‐phosphosulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 Å resolution reveals a new fold with a novel active site

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2006, Proteins.

Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2006 .

Crystal structure of virulence factor CJ0248 from Campylobacter jejuni at 2.25 Å resolution reveals a new fold

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2005, Proteins.

Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 Å resolution reveals a new fold

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2005, Proteins.

Biochemical and structural characterization of the putative dihydropteroate synthase ortholog Rv1207 of Mycobacterium tuberculosis.

P. Niyomrattanakit, G. Spraggon, T. Dick, 2008, FEMS microbiology letters.