A. Metz

A. Metz, K. Seemann, C. Saal, 2015, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A key role for stress-induced satellite III transcripts in the relocalization of splicing factors into nuclear stress granules

Caroline Jolly, Jamal Tazi, J. Tazi, 2004, Journal of Cell Science.

Stress-induced transcription of satellite III repeats

M. Vigneron, B. Turner, A. Metz, 2004, The Journal of cell biology.

Modulating protein-protein interactions: from structural determinants of binding to druggability prediction to application.

Holger Gohlke, Alexander Metz, Emanuele Ciglia, 2012, Current pharmaceutical design.

One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit Lists

Timo Krotzky, Gerhard Klebe, Nedyalka Radeva, 2015, ChemMedChem.

RNAi silencing of P/Q-type calcium channels in Purkinje neurons of adult mouse leads to episodic ataxia type 2

L. Fagni, P. Lory, A. Metz, 2014, Neurobiology of Disease.

Six Biophysical Screening Methods Miss a Large Proportion of Crystallographically Discovered Fragment Hits: A Case Study.

Johannes Schiebel, Xiaojie Wang, Martin Stieler, 2016, ACS chemical biology.

Soaking suggests “alternative facts”: Only co-crystallization discloses major ligand-induced interface rearrangements of a homodimeric tRNA-binding protein indicating a novel mode-of-inhibition

Luzi J. Barandun, G. Klebe, F. Diederich, 2017, PloS one.

Workflow and Tools for Crystallographic Fragment Screening at the Helmholtz-Zentrum Berlin.

G. Klebe, A. Heine, M. Weiss, 2021, Journal of visualized experiments : JoVE.

From Determinants of RUNX1/ETO Tetramerization to Small-Molecule Protein-Protein Interaction Inhibitors Targeting Acute Myeloid Leukemia

Holger Gohlke, Manuel Grez, Alexander Metz, 2013, J. Chem. Inf. Model..

Frag4Lead: growing crystallographic fragment hits by catalog using fragment-guided template docking

G. Klebe, A. Heine, M. Weiss, 2021, Acta crystallographica. Section D, Structural biology.

Modular Solid-Phase Synthesis of Teroxazoles as a Class of α-Helix Mimetics

H. Gohlke, M. Göbel, J. Bats, 2012 .

Structures of endothiapepsin-fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment library.

Gerhard Klebe, Manfred S Weiss, Xiaojie Wang, 2016, Acta crystallographica. Section F, Structural biology communications.

Hot Spots and Transient Pockets: Predicting the Determinants of Small-Molecule Binding to a Protein-Protein Interface

Holger Gohlke, Hannes Kopitz, Alexander Metz, 2012, J. Chem. Inf. Model..

Six Biophysical Screening Methods Miss a Large Proportion of Crystallographically Discovered Fragment Hits: A Case Study.

G. Klebe, A. Heine, M. Weiss, 2016, ACS chemical biology.