P. Majerus

发表

Crystal structure of inositol polyphosphate 1-phosphatase at 2.3-A resolution.

F. S. Mathews, J. Ponder, J. York, 1994, Biochemistry.

Collaborative overview of randomised trials of antiplatelet therapy Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients

Walker, R. Collins, V. Fuster, 1994 .

Health, air pollution, and animal agriculture

Nicolas Treich, P. Majerus, Emmanuelle Lavaine, 2020, Review of Agricultural, Food and Environmental Studies.

Increased Levels of Inositol Hexakisphosphate (InsP6) Protect HEK293 Cells from Tumor Necrosis Factor α- and Fas-induced Apoptosis*

P. Majerus, J. Verbsky, 2005, Journal of Biological Chemistry.

Cyclic adenosine 3',5'-monophosphate inhibits the availability of arachidonate to prostaglandin synthetase in human platelet suspensions.

P. Needleman, P. Majerus, G. Roth, 1977, The Journal of clinical investigation.

Sensitivity of fatty acid cyclooxygenase from human aorta to acetylation by aspirin.

P. Majerus, N. Stanford, J. Burch, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Acetylation of prostaglandin synthase by aspirin.

G J Roth, P. Majerus, G. Roth, 1975, Proceedings of the National Academy of Sciences of the United States of America.

A role for thrombomodulin in the pathogenesis of thrombin-induced thromboembolism in mice

P. Majerus, W. Dittman, T. Kumada, 1988 .

Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure.

J. Ponder, J. York, P. Majerus, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of 1,2-diacylglycerol hydrolysis in human platelets. Demonstration of an arachidonoyl-monoacylglycerol intermediate.

P. Majerus, S. Prescott, 1983, The Journal of biological chemistry.

Eicosadiynoic acid: a non-toxic inhibitor of multiple enzymatic steps in the production of icosanoids from arachidonic acid.

P. Majerus, M. Laposata, E. Reich, 1987, Prostaglandins.

Inositol polyphosphate multikinase regulates inositol 1,4,5,6-tetrakisphosphate.

P. Majerus, Shao-chun Chang, 2006, Biochemical and biophysical research communications.

Inositol Hexakisphosphate Binds to Clathrin Assembly Protein 3 (AP-3/AP180) and Inhibits Clathrin Cage Assembly in Vitro(*)

P. Majerus, F. Norris, E. Ungewickell, 1995, The Journal of Biological Chemistry.

Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2

D. Pot, F. Masiarz, P. Majerus, 1996, Current Biology.

The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase.

P. Majerus, G. Krystal, A. Jefferson, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Multiple forms of the SH2-containing inositol phosphatase, SHIP, are generated by C-terminal truncation.

P. Majerus, G. Krystal, J. Damen, 1998 .

The inositol polyphosphate 5-phosphatase Ocrl associates with endosomes that are partially coated with clathrin.

P. Majerus, E. Ungewickell, A. Ungewickell, 2004, Proceedings of the National Academy of Sciences of the United States of America.

The Role of Phosphatases in Inositol Signaling Reactions*

P. Majerus, F. Norris, M. Kisseleva, 1999, The Journal of Biological Chemistry.

Mutations in the inositol polyphosphate-5-phosphatase E gene link phosphatidyl inositol signaling to the ciliopathies

E. Bertini, S. Schurmans, H. Kayserili, 2009, Nature Genetics.

The Pathway for the Production of Inositol Hexakisphosphate in Human Cells*

P. Majerus, J. Verbsky, Y. Mochizuki, 2005, Journal of Biological Chemistry.

Phosphatidylinositol-4-phosphate 5-Kinase Isozymes Catalyze the Synthesis of 3-Phosphate-containing Phosphatidylinositol Signaling Molecules*

Gregory J. Parker, G. Prestwich, J. Chen, 1997, The Journal of Biological Chemistry.

The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity.

J. Hurley, P. Majerus, J. Kunz, 2000, Molecular cell.

Formation of phosphatidylinositol 3-phosphate by isomerization from phosphatidylinositol 4-phosphate.

J. Walsh, P. Majerus, K. Caldwell, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Activation of coagulation factor V by a platelet protease.

P. Majerus, W. Kane, J. Mruk, 1982, The Journal of clinical investigation.

Acetylation of prostaglandin synthetase by aspirin. Purification and properties of the acetylated protein from sheep vesicular gland.

P. Majerus, G. Roth, N. Stanford, 1977, Biochemistry.

Inhibition of platelet prostaglandin synthetase by oral aspirin.

P. Majerus, N. Stanford, J. Burch, 1978, The Journal of clinical investigation.

Properties of the factor Xa binding site on human platelets.

J. Miletich, P. Majerus, C. Jackson, 1978, The Journal of biological chemistry.

Relationships between platelets and coagulation factors in hemostasis.

J. Miletich, P. Majerus, 1978, Annual review of medicine.

The role of prostaglandins in platelet function.

P. Majerus, J. Burch, 1979, Seminars in hematology.

The synthesis of sulfated dextran beads for isolation of human plasma coagulation factors II, IX, and X.

J. Miletich, P. Majerus, G. Broze, 1980, Analytical biochemistry.

Isolation and quantitation of the platelet membrane glycoprotein deficient in thrombasthenia using a monoclonal hybridoma antibody.

P. Majerus, R. McEver, N. Baenziger, 1980, The Journal of clinical investigation.

Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9

P. Majerus, Y. Mochizuki, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Inositol 1,3,4-Trisphosphate 5/6-Kinase Associates with the COP9 Signalosome by Binding to CSN1*

Young Sun, P. Majerus, M. Wilson, 2002, The Journal of Biological Chemistry.

Inositol 1,3,4-Trisphosphate 5/6-Kinase Is a Protein Kinase That Phosphorylates the Transcription Factors c-Jun and ATF-2*

P. Majerus, Li Cao, Monita P. Wilson, 2001, The Journal of Biological Chemistry.

Inositol 1,3,4-Trisphosphate 5/6-Kinase Inhibits Tumor Necrosis Factor-induced Apoptosis*

Young Sun, P. Majerus, Y. Mochizuki, 2003, Journal of Biological Chemistry.

The cDNA Cloning and Characterization of Inositol Polyphosphate 4-Phosphatase Type II

R. Atkins, P. Majerus, F. Norris, 1997, The Journal of Biological Chemistry.

Hydrolysis of phosphatidylinositol 3,4-bisphosphate by inositol polyphosphate 4-phosphatase isolated by affinity elution chromatography.

P. Majerus, F. Norris, 1994, The Journal of biological chemistry.

Arachidonate metabolism in vascular disorders.

P. Majerus, 1983, The Journal of clinical investigation.

Thrombomodulin, an endothelial anticoagulant protein, is absent from the human brain

C. Bell, P. Majerus, H. Ishii, 1986 .

Thrombomodulin, an endothelial anticoagulant protein, is absent from the human brain.

C. Bell, P. Majerus, H. Ishii, 1986, Blood.

Identity of inositol 1,2-cyclic phosphate 2-phosphohydrolase with lipocortin III.

P. Majerus, J. Tait, T. Ross, 1990, Science.

Inositol polyphosphate 4-phosphatase type I regulates cell growth downstream of transcription factor GATA-1.

P. Vyas, R. Joseph, P. Majerus, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Properties of Type II Inositol Polyphosphate 5-Phosphatase (*)

P. Majerus, A. B. Jefferson, 1995, The Journal of Biological Chemistry.

A thrombin-sensitive protein of human platelet membranes.

P. Majerus, N. Baenziger, G. Brodie, 1971, Proceedings of the National Academy of Sciences of the United States of America.

Purification and properties of human coagulation factor VII.

P. Majerus, G. Broze, George J. Broze, 1980, The Journal of biological chemistry.

Characterization of a cDNA encoding Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase.

P. Majerus, M. P. Wilson, Monita P. Wilson, 1997, Biochemical and biophysical research communications.

Inositol phosphates: synthesis and degradation.

P. Majerus, R. Inhorn, T. Ross, 1988, The Journal of biological chemistry.

How does the brain function during starvation ? 1972 – 1977

T. Stossel, A. Varki, P. Insel, 2004 .

The role of myotubularin-related phosphatases in the control of autophagy and programmed cell death.

P. Majerus, David B. Wilson, Shao-chun Chang, 2012, Advances in biological regulation.

MTMR9 Increases MTMR6 Enzyme Activity, Stability, and Role in Apoptosis*

P. Majerus, Shao-chun Chang, Jasna A Marjanovic, 2009, Journal of Biological Chemistry.

Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP

M. Layton, P. Majerus, C. Mitchell, 2003, Proceedings of the National Academy of Sciences of the United States of America.

The effects of mepacrine and p-bromophenacyl bromide on arachidonic acid release in human platelets.

P. Majerus, S. Prescott, S. Hofmann, 1982, Archives of biochemistry and biophysics.

SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase.

P. Majerus, F. Norris, T. Wallis, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Acetyl coenzyme A carboxylase. The roles of synthesis and degradation in regulation of enzyme levels in rat liver.

P. Majerus, E. Kilburn, 1969, Journal of Biological Chemistry.

Cell Lines from Kidney Proximal Tubules of a Patient with Lowe Syndrome Lack OCRL Inositol Polyphosphate 5-Phosphatase and Accumulate Phosphatidylinositol 4,5-Bisphosphate*

E. Philip, P. Majerus, L. Racusen, 1998, The Journal of Biological Chemistry.

[18] Purification of human coagulation factors II, IX, and X using sulfated dextran beads

J. Miletich, P. Majerus, G. Broze, 1981 .

The binding of human and bovine thrombin to human platelets.

P. Majerus, M. Shuman, D. Tollefsen, 1976, Blood.

Thrombomodulin as a marker for vascular tumors. Comparative study with factor VIII and Ulex europaeus I lectin.

P. Majerus, I. Maruyama, S. Yonezawa, 1987, American journal of clinical pathology.

High affinity esterification of eicosanoid precursor fatty acids by platelets.

E. Neufeld, P. Majerus, H. Sprecher, 1983, The Journal of clinical investigation.

of Platelet Prostaglandin Synthetase by Oral Aspirin

P. Majerus, N. Stanford, J. Burch, 1978 .

Prevention of thrombosis in patients on hemodialysis by low-dose aspirin.

P. Majerus, H. Harter, J. Delmez, 1979, The New England journal of medicine.

The regulation of fatty acid biosynthesis in rat hepatomas.

H. Morris, P. Majerus, M. Smith, 1968, Journal of Biological Chemistry.

Thrombin-induced protein phosphorylation in human platelets.

P. Majerus, R. Lyons, N. Stanford, 1975, The Journal of clinical investigation.

Biosynthesis of coagulation Factor V by a human hepatocellular carcinoma cell line.

P. Majerus, I. Maruyama, D. B. Wilson, 1984, The Journal of clinical investigation.

Patients with congenital factor V deficiency have decreased factor Xa binding sites on their platelets.

J. Miletich, P. Majerus, D. Majerus, 1978, The Journal of clinical investigation.

Interaction of coagulation factor Xa with human platelets.

J. Miletich, P. Majerus, C. Jackson, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Arachidonoyl-CoA synthetase. Separation from nonspecific acyl-CoA synthetase and distribution in various cells and tissues.

P. Majerus, M. Laposata, E. Reich, 1985, The Journal of biological chemistry.

Isolation and characterization of thrombomodulin from human placenta.

P. Majerus, I. Maruyama, H. Ishii, 1984, The Journal of biological chemistry.

Human thrombomodulin is not an efficient inhibitor of the procoagulant activity of thrombin.

P. Majerus, I. Maruyama, H. Ishii, 1985, The Journal of clinical investigation.

The protein tyrosine phosphatase SHP-1 regulates integrin-mediated adhesion of macrophages

T. Roach, P. Majerus, Xiaoling Zhang, 1998, Current Biology.

Phosphoinositide-specific Inositol Polyphosphate 5-Phosphatase IV Inhibits Akt/Protein Kinase B Phosphorylation and Leads to Apoptotic Cell Death*

P. Majerus, Li Cao, M. Kisseleva, 2002, The Journal of Biological Chemistry.

Isolation and characterization of two 3-phosphatases that hydrolyze both phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate.

P. Majerus, V. Bansal, D. Lips, 1991, The Journal of biological chemistry.

The Isolation and Characterization of cDNA Encoding Human and Rat Brain Inositol Polyphosphate 4-Phosphatase (*)

P. Majerus, F. Norris, V. Auethavekiat, 1995, The Journal of Biological Chemistry.

Inositol Polyphosphate 4-Phosphatase Is Inactivated by Calpain-mediated Proteolysis in Stimulated Human Platelets*

R. Atkins, P. Majerus, F. Norris, 1997, The Journal of Biological Chemistry.

Isolation and characterization of the inositol cyclic phosphate products of phosphoinositide cleavage by phospholipase C. Metabolism in cell-free extracts.

P. Majerus, D. Wilson, T. Connolly, 1986, The Journal of biological chemistry.

The Isolation and Characterization of a cDNA Encoding Phospholipid-specific Inositol Polyphosphate 5-Phosphatase*

P. Majerus, M. Kisseleva, Monita P. Wilson, 2000, The Journal of Biological Chemistry.

Uptake and subcellular distribution of [3H]arachidonic acid in murine fibrosarcoma cells measured by electron microscope autoradiography

E. Neufeld, J. Saffitz, P. Majerus, 1985, The Journal of cell biology.

Isolation of human platelets and platelet surface membranes.

P. Majerus, N. Baenziger, 1974, Methods in enzymology.

The Properties of the Protein Tyrosine Phosphatase PTPMEG*

P. Majerus, Minxiang Gu, M. Gu, 1996, The Journal of Biological Chemistry.

Structure and function of thrombomodulin: a natural anticoagulant.

William, Dittman, P. Majerus, 1990, Blood.

Phosphoinositide phosphatases and disease This work is supported by funds from the Howard Hughes Medical Institute (J.D.Y.), and from the National Institutes of Health HL-55672 (J.D.Y.) and HL-016634 (P.W.M.) Published, JLR Papers in Press, November 11, 2008.

J. York, P. Majerus, 2009, Journal of Lipid Research.

Isolation of Inositol 1,3,4-Trisphosphate 5/6-Kinase, cDNA Cloning, and Expression of the Recombinant Enzyme (*)

P. Majerus, M. P. Wilson, Monita P. Wilson, 1996, The Journal of Biological Chemistry.

The role of inositol polyphosphate 4-phosphatase 1 in platelet function using a weeble mouse model.

P. Majerus, Chunfen Zhang, P. Nicholas, 2011, Advances in enzyme regulation.

Akt2 Modulates Glucose Availability and Downstream Apoptotic Pathways during Development*

P. Majerus, M. Carayannopoulos, Penny J. Jensen, 2010, The Journal of Biological Chemistry.

Overexpression of the inositol phosphatase SopB in human 293 cells stimulates cellular chloride influx and inhibits nuclear mRNA export.

P. Majerus, Yucheng Feng, Y. Feng, 2001, Proceedings of the National Academy of Sciences of the United States of America.

The inositol polyphosphate 4-phosphatase forms a complex with phosphatidylinositol 3-kinase in human platelet cytosol.

P. Majerus, C. Mitchell, F. Norris, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Inositols do it all.

P. Majerus, 1996, Genes & development.

The isolation and characterization of inositol polyphosphate 4-phosphatase.

P. Majerus, V. Bansal, K. Caldwell, 1990, The Journal of biological chemistry.

Generated by C-Terminal Truncation Multiple Forms of the SH2-Containing Inositol Phosphatase, SHIP, Are

P. Majerus, G. Krystal, J. Damen, 2013 .

Multiple forms of the SH2-containing inositol phosphatase, SHIP, are generated by C-terminal truncation.

P. Majerus, G. Krystal, L. Liu, 1998, Blood.

The discovery of a 3-phosphomonoesterase that hydrolyzes phosphatidylinositol 3-phosphate in NIH 3T3 cells.

P. Majerus, D. Lips, 1989, Journal of Biological Chemistry.

Protein kinase C phosphorylates human platelet inositol trisphosphate 5′-phosphomonoesterase, increasing the phosphatase activity

P. Majerus, T. Connolly, W. J. Lawing, 1986, Cell.

The Synthesis of Inositol Hexakisphosphate

P. Majerus, J. Verbsky, M. Kisseleva, 2002, The Journal of Biological Chemistry.

Inhibition of human platelet aggregation by monovalent antifibrinogen antibody fragments.

P. Majerus, D. Tollefsen, 1975, The Journal of clinical investigation.

Evidence for a single class of thrombin-binding sites of human platelets.

P. Majerus, D. Tollefsen, 1976, Biochemistry.

ofte AMERICAN HEART ASSOCIATION NO . 3 1976 EDITORIAL Why Aspirin ?

P. Majerus, 2022 .

The structure and function of mouse thrombomodulin. Phorbol myristate acetate stimulates degradation and synthesis of thrombomodulin without affecting mRNA levels in hemangioma cells.

P. Majerus, J. Sadler, W. Dittman, 1988, The Journal of biological chemistry.

Bradykinin-stimulated release of arachidonate from phosphatidyl inositol in mouse fibrosarcoma cells.

P. Majerus, R. Bell, N. Baenziger, 1980, Prostaglandins.

Thrombin-induced hydrolysis of phosphatidylinositol in human platelets.

P. Majerus, R. Bell, 1980, The Journal of biological chemistry.

Signaling Inositol Polyphosphate-5-phosphatase

D. Pot, P. Majerus, L. Williams, 1997, The Journal of Biological Chemistry.

The effect of overexpression of the protein tyrosine phosphatase PTPMEG on cell growth and on colony formation in soft agar in COS-7 cells.

P. Majerus, K. Meng, M. Gu, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Arachidonate release and phosphatidic acid turnover in stimulated human platelets.

E. Neufeld, P. Majerus, 1983, The Journal of biological chemistry.

Phosphatidylinositol 3-phosphate is present in normal and transformed fibroblasts and is resistant to hydrolysis by bovine brain phospholipase C II.

A. T. Young, P. Majerus, T. Benjamin, 1989, The Journal of biological chemistry.

Isolation and properties of a thrombin-sensitive protein of human platelets.

P. Majerus, N. Baenziger, G. Brodie, 1972, The Journal of biological chemistry.

Coagulation factor Va binds to human umbilical vein endothelial cells and accelerates protein C activation.

P. Majerus, I. Maruyama, H. Salem, 1984, The Journal of clinical investigation.

Thrombin-stimulated immunoprecipitation of phosphatidylinositol 3-kinase from human platelets.

J. Brugge, P. Majerus, C. Mitchell, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Cloning, heterologous expression, and chromosomal localization of human inositol polyphosphate 1-phosphatase.

J. York, P. Majerus, H. Donis-Keller, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Factor Va-dependent binding of factor Xa to human platelets.

P. Majerus, W. Kane, C. Jackson, 1980, The Journal of biological chemistry.

Bad blood by mutation

P. Majerus, 1994, Nature.

Cloning and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to retinaldehyde-binding protein and yeast SEC14p.

P. Majerus, I. Warshawsky, M. Gu, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases.

P. Majerus, Yucheng Feng, A. Ungewickell, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Inositol polyphosphate 1-phosphatase is present in the nucleus and inhibits DNA synthesis.

J. York, J. Saffitz, P. Majerus, 1994, The Journal of biological chemistry.

Isolation of vitamin B12-binding proteins using affinity chromatography. 3. Purification and properties of human plasma transcobalamin II.

P. Majerus, R. Allen, 1972, The Journal of biological chemistry.

Characterization of prostacyclin synthesis in cultured human arterial smooth muscle cells, venous endothelial cells and skin fibroblasts

P. Majerus, P. Becherer, N. Baenziger, 1979, Cell.

The effects of thrombin on adenyl cyclase activity and a membrane protein from human platelets.

P. Majerus, N. Baenziger, L. Chase, 1972, The Journal of clinical investigation.

Uptake and release of arachidonate by platelets.

E. Neufeld, P. Majerus, S. Prescott, 1983, Advances in prostaglandin, thromboxane, and leukotriene research.

INO-4995 therapeutic efficacy is enhanced with repeat dosing in cystic fibrosis knockout mice and human epithelia.

M. Drumm, P. Majerus, S. Gabriel, 2010, American journal of respiratory cell and molecular biology.

An aspirin a day.

P. Majerus, 2014, Advances in biological regulation.

ANOFFICIAL JOURNAL ofte AMERICAN HEARTASSOCIATION

P. Majerus, 2017 .

The Human Homolog of the Rat Inositol Phosphate Multikinase Is an Inositol 1,3,4,6-Tetrakisphosphate 5-Kinase*

P. Majerus, Yucheng Feng, Shao-chun Chang, 2002, The Journal of Biological Chemistry.

Transcription of thrombomodulin mRNA in mouse hemangioma cells is increased by cycloheximide and thrombin.

P. Majerus, W. Dittman, T. Kumada, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Glutathione synthesis in human erythrocytes. II. Purification and properties of the enzymes of glutathione biosynthesis.

P. Majerus, M. Smith, V. Minnich, 1971, The Journal of clinical investigation.

ACYL-CARRIER PROTEIN. II. INTERMEDIARY REACTIONS OF FATTY ACID SYNTHESIS.

B. Talamo, P. Majerus, A. Alberts, 1964, Biochemistry.

Discovery of an arachidonoyl coenzyme A synthetase in human platelets.

P. Majerus, D. Wilson, S. Prescott, 1982, The Journal of biological chemistry.

An Entamoeba histolytica inositol 1,3,4-trisphosphate 5/6-kinase has a novel 3-kinase activity.

P. Majerus, J. Samuelson, M. P. Wilson, 2000, Molecular and biochemical parasitology.

A Novel Phosphatidylinositol-3,4,5-trisphosphate 5-Phosphatase Associates with the Interleukin-3 Receptor*

P. Majerus, G. Krystal, F. Norris, 1996, The Journal of Biological Chemistry.

Pathway for the formation of D-3 phosphate containing inositol phospholipids in intact human platelets.

P. Majerus, C. Mitchell, V. Bansal, 1990, Journal of Biological Chemistry.

Human coagulation factor Va is a cofactor for the activation of protein C.

J. Miletich, P. Majerus, G. Broze, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Fatty acid biosynthesis in human leukocytes.

P. Majerus, R. Lastra, 1967, The Journal of clinical investigation.

Prostaglandins: Critical roles in pregnancy and colon cancer

P. Majerus, 1998, Current Biology.

Expression of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) and its role in neural tube defects.

P. Majerus, Chunfen Zhang, David B. Wilson, 2010, Advances in enzyme regulation.

Neural tube defects in mice with reduced levels of inositol 1,3,4-trisphosphate 5/6-kinase

P. Majerus, David B. Wilson, P. Nicholas, 2009, Proceedings of the National Academy of Sciences.

Disruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expression.

P. Majerus, K. Lavine, J. Verbsky, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Purification and characterization of human coagulation factor V.

P. Majerus, W. Kane, W. H. Kane, 1981, The Journal of biological chemistry.

Cultured human skin fibroblasts and arterial cells produce a labile platelet-inhibitory prostaglandin.

P. Majerus, N. Baenziger, M. Dillender, 1977, Biochemical and biophysical research communications.

Deficiency of factor Xa-factor Va binding sites on the platelets of a patient with a bleeding disorder.

J. Miletich, P. Majerus, W. Kane, 1979, Blood.

The v-sis oncogene product but not platelet-derived growth factor (PDGF) a homodimers activate PDGF α and β receptors intracellularly and initiate cellular transformation

Dean Y. Li, B. Bejcek, P. Majerus, 1992 .

Lack of covalent modification of prostaglandin synthetase (cyclo-oxygenase) by indomethacin.

P. Majerus, G. Roth, N. Stanford, 1977, Prostaglandins.

Isolation of a phosphomonoesterase from human platelets that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate.

P. Majerus, T. Connolly, T. E. Bross, 1985, The Journal of biological chemistry.

Hydrolysis of polyphosphoinositides by purified sheep seminal vesicle phospholipase C enzymes.

P. Majerus, D. Wilson, S. Hofmann, 1984, The Journal of biological chemistry.

Nuclear phosphatidylinositols decrease during S-phase of the cell cycle in HeLa cells.

J. York, P. Majerus, John D. York, 1994, The Journal of biological chemistry.

The turnover of thrombin-thrombomodulin complex in cultured human umbilical vein endothelial cells and A549 lung cancer cells. Endocytosis and degradation of thrombin.

P. Majerus, I. Maruyama, 1985, The Journal of biological chemistry.

Comparative effects of aspirin and diflunisal on prostaglandin synthetase from human platelets and sheep seminal vesicles.

P. Majerus, N. Stanford, 1977, British journal of clinical pharmacology.

Phosphorylation of Platelet Pleckstrin Activates Inositol Polyphosphate 5-Phosphatase I*

P. Majerus, C. Abrams, V. Auethavekiat, 1997, The Journal of Biological Chemistry.

Complex Interaction between Factor Va‐Light Chain and Thrombomodulin in the Regulation of Protein C Activation a

C. Esmon, P. Majerus, N. Esmon, 1986, Annals of the New York Academy of Sciences.

Mutation of the conserved domains of two inositol polyphosphate 5-phosphatases.

P. Majerus, A. B. Jefferson, 1996, Biochemistry.

Cloning and expression of human 75-kDa inositol polyphosphate-5-phosphatase.

P. Majerus, C. Mitchell, T. Ross, 1991, The Journal of biological chemistry.

The metabolism of tris- and tetraphosphates of inositol by 5-phosphomonoesterase and 3-kinase enzymes.

P. Majerus, T. Connolly, R. Irvine, 1987, The Journal of biological chemistry.

Identification and properties of two distinct phosphatidylinositol-specific phospholipase C enzymes from sheep seminal vesicular glands.

P. Majerus, S. Hofmann, 1982, The Journal of biological chemistry.

The role of inositol signaling in the control of apoptosis.

P. Majerus, M. Kisseleva, Jasna A Marjanovic, 2008, Advances in enzyme regulation.

[5] Mechanism of saturated fatty acid biosynthesis in Escherichia coli

P. Majerus, A. Alberts, P. Vagelos, 1969 .

Isolation of vitamin B12-binding proteins using affinity chromatography. II. Purification and properties of a human granulocyte vitamine B12-binding protein.

P. Majerus, R. Allen, 1972, The Journal of biological chemistry.

The perturbation of thrombin binding to human platelets by anions.

P. Majerus, M. Shuman, 1975, The Journal of clinical investigation.

Sequence of a cDNA for mouse thrombomodulin and comparison of the predicted mouse and human amino acid sequences.

P. Majerus, W. Dittman, 1989, Nucleic acids research.

Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene.

L. Deaven, P. Majerus, R. Ye, 1987, Biochemistry.

Protein C inhibits endocytosis of thrombin−thrombomodulin complexes in A549 lung cancer cells and human umbilical vein endothelial cells

P. Majerus, I. Maruyama, 1987 .

Thrombomodulin is found on endothelium of arteries, veins, capillaries, and lymphatics, and on syncytiotrophoblast of human placenta

C. Bell, P. Majerus, I. Maruyama, 1985, The Journal of cell biology.

Thrombomodulin is present in human plasma and urine.

P. Majerus, H. Ishii, 1985, The Journal of clinical investigation.

Binding of the products of prothrombin activation to human platelets.

P. Majerus, D. Tollefsen, C. Jackson, 1975, The Journal of clinical investigation.

[19] Human factor VII

P. Majerus, G. Broze, 1981 .

Lipid metabolism in human platelets.

P. Majerus, N. Baenziger, G. N. Brodie, 1969, Series haematologica.

Isolation of vitamin B12-binding proteins using affinity chromatography. I. Preparation and properties of vitamin B12-sepharose.

P. Majerus, R. Allen, 1972, The Journal of biological chemistry.

CHAPTER 18 – Phosphatidylinositol Phospholipase C

P. Majerus, H. Deckmyn, B. Whiteley, 1990 .

The metabolism of phosphoinositide-derived messenger molecules.

P. Majerus, H. Deckmyn, T. Ross, 1986, Science.

Isolation and characterization of the inositol cyclic phosphate products of polyphosphoinositide cleavage by phospholipase C. Physiological effects in permeabilized platelets and Limulus photoreceptor cells.

J. Brown, W. Sherman, P. Majerus, 1985, The Journal of biological chemistry.

Lipid metabolism in human platelets. I. Evidence for a complete fatty acid synthesizing system.

P. Majerus, G. Clamon, M. Smith, 1969, The Journal of clinical investigation.

Fatty acid biosynthesis and the role of the acyl carrier protein.

P. Majerus, P. Vagelos, 1967, Advances in lipid research.

The regulation of fatty acid biosynthesis in human skin fibroblasts.

P. Majerus, W. Sly, R. Jacobs, 1973, The Journal of biological chemistry.

Glutathione synthetase deficiency as a cause of hereditary hemolytic disease.

P. Majerus, M. Garrick, C. Hess, 1970, The New England journal of medicine.

Diglyceride lipase: a pathway for arachidonate release from human platelets.

P. Majerus, D. Kennerly, R. Bell, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Lipid metabolism in human platelets. II. De novo phospholipid synthesis and the effect of thrombin on the pattern of synthesis.

P. Majerus, N. Lewis, 1969, The Journal of clinical investigation.

[6] Acyl carrier protein from Escherichia coli

P. Majerus, A. Alberts, P. Vagelos, 1969 .

ACYL CARRIER PROTEIN. IV. THE IDENTIFICATION OF 4'-PHOSPHOPANTETHEINE AS THE PROSTHETIC GROUP OF THE ACYL CARRIER PROTEIN.

P. Majerus, A. Alberts, P. Vagelos, 1965, Proceedings of the National Academy of Sciences of the United States of America.

THE ACYL CARRIER PROTEIN OF FATTY ACID SYNTHESIS: PURIFICATION, PHYSICAL PROPERTIES, AND SUBSTRATE BINDING SITE.

P. Majerus, A. Alberts, P. Vagelos, 1964, Proceedings of the National Academy of Sciences of the United States of America.

Acyl carrier protein. VII. The primary structure of the substrate-binding site.

P. Majerus, A. Alberts, P. Vagelos, 1965, The Journal of biological chemistry.

Acyl carrier protein. Structural requirements for function in fatty acid biosynthesis.

P. Majerus, 1967, The Journal of biological chemistry.

[11] β-Hydroxybutyryl acyl carrier protein dehydrase from Escherichia coli

P. Majerus, A. Alberts, P. Vagelos, 1969 .

Acyl Carrier Protein: Effects of Acetylation and Tryptic Hydrolysis on Function in Fatty Acid Synthesis

P. Majerus, 1968, Science.

THE MECHANISM OF FATTY ACID BIOSYNTHESIS AND THE INVOLVEMENT OF AN ACYL CARRIER PROTEIN

P. Majerus, A. Alberts, P. Vagelos, 1965, Annals of the New York Academy of Sciences.

The measurement of thrombin in clotting blood by radioimmunoassay.

P. Majerus, M. Shuman, P W Majerus, 1976, The Journal of clinical investigation.

Use of vitamin B 12 in affinity chromatography.

R. L. Burger, P. Majerus, R. Allen, 1974, Methods in enzymology.

THE EFFECTS OF THROMBIN ON PHYTOHEMAGGLUTININ RECEPTOR SITES IN HUMAN PLATELETS

D. Chaplin, P. Majerus, T. Tillack, 1974, The Journal of cell biology.

PHYTOHEMAGGLUTININ RECEPTOR SITES IN HUMAN PLATELETS

D. Chaplin, P. Majerus, T. Tillack, 1974 .

Glutathione biosynthesis in human erythrocytes. I. Identification of the enzymes of glutathione synthesis in hemolysates.

P. Majerus, M. Smith, V. Minnich, 1971, The Journal of clinical investigation.

The binding of thrombin to the surface of human platelets.

P. Majerus, D. Tollefsen, J. Feagler, 1974, The Journal of biological chemistry.

Isolation and structural characterization of the polypeptide subunits of membrane glycoprotein IIb-IIIa from human platelets.

P. Majerus, R. McEver, J. Baenziger, 1982, Blood.

Production of phosphoinositide-derived messengers

E. Neufeld, P. Majerus, D. Wilson, 1984, Cell.

RHC 80267 does not inhibit the diglyceride lipase pathway in intact platelets.

P. Majerus, S. Prescott, T. E. Bross, 1983, Biochemical and biophysical research communications.

Characterization and assay of diacylglycerol lipase from human platelets.

P. Majerus, S. Prescott, 1982, Methods in enzymology.

Induction of the platelet release reaction by phytohemagglutinin.

P. Majerus, D. Tollefsen, J. Feagler, 1974, The Journal of clinical investigation.

Phosphoinositide turnover provides a link in stimulus—response coupling

E. Neufeld, P. Majerus, T. Connolly, 1985 .

Inositol cyclic phosphates are produced by cleavage of phosphatidylphosphoinositols (polyphosphoinositides) with purified sheep seminal vesicle phospholipase C enzymes.

W. Sherman, P. Majerus, R. A. Berger, 1985, Proceedings of the National Academy of Sciences of the United States of America.

The Phosphatidylinositol Pathway of Platelets and Vascular Cells a

P. Majerus, C. Mitchell, V. Bansal, 1991, Annals of the New York Academy of Sciences.

EFFECT OF THROMBIN ON THE PATTERN OF SYNTHESIS NANCY

P. Majerus, N. Lewis, 2022 .

Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1.

J. York, P. Majerus, I. Warshawsky, 1991, Proceedings of the National Academy of Sciences of the United States of America.

P. Majerus, Chunfen Zhang, M. Kisseleva, 2012, Proceedings of the National Academy of Sciences.

The Inositol 5′-Phosphatase SHIP Binds to Immunoreceptor Signaling Motifs and Responds to High Affinity IgE Receptor Aggregation*

M. Osborne, L. Cantley, P. Majerus, 1996, The Journal of Biological Chemistry.

Blasts from the past.

Paul A Insel, T. Stossel, A. Varki, 2004, The Journal of clinical investigation.

The fatty acid composition of phosphatidylinositol from thrombin-stimulated human platelets.

P. Majerus, S. Prescott, 1981, The Journal of biological chemistry.

The regulation of fatty acid synthesis in human skin fibroblasts. Inhibition of fatty acid synthesis by free fatty acids.

P. Majerus, R. Jacobs, 1973, The Journal of biological chemistry.

Phosphoinositide interconversion in thrombin-stimulated human platelets.

E. Neufeld, P. Majerus, D. Wilson, 1985, The Journal of biological chemistry.

Aspirin as a quantitative acetylating reagent for the fatty acid oxygenase that forms prostaglandins.

P. Majerus, W. Lands, G. Roth, 1976, Prostaglandins.

The mechanism of the effect of aspirin on human platelets. I. Acetylation of a particulate fraction protein.

P. Majerus, G. Roth, 1975, The Journal of clinical investigation.

Inherited predisposition to thrombosis

J. Miletich, P. Majerus, Raymond White, 1993, Cell.

Regulation of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) by reversible lysine acetylation

Chunfen Zhang, P. Majerus, Chunfen Zhang, 2012, Proceedings of the National Academy of Sciences.

Fatty acid structural requirements for activity of arachidonoyl-CoA synthetase.

E. Neufeld, P. Majerus, H. Sprecher, 1984, Journal of lipid research.

Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers

G. Giles, J. Rasko, L. Baglietto, 2010, Proceedings of the National Academy of Sciences.

The binding of phytohemagglutinins to human platelet plasma membranes.

P. Majerus, G. N. Brodie, 1972, The Journal of biological chemistry.

The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphatase.

P. Majerus, X. Zhang, A. B. Jefferson, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: Identification of a myotubularin-related protein lacking catalytic activity

J. Whisstock, M. Layton, P. Majerus, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Recent insights in phosphatidylinositol signaling

P. Majerus, T. Ross, V. Bansal, 1990, Cell.

Inositol polyphosphate 4-phosphatase B as a regulator of bone mass in mice and humans.

Michel G. Arsenault, J. Vacher, P. Majerus, 2011, Cell metabolism.

Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4‐phosphatase‐1

P. Majerus, C. Mitchell, T. Tiganis, 2009, EMBO reports.

Acyl Carrier Protein. VI. Purification and Properties of β-Ketoacyl Acyl Carrier Protein Synthetase*

P. Majerus, A. Alberts, P. Vagelos, 1965 .

The anticoagulant properties of thrombomodulin

C. Bell, P. Majerus, C. Mitchell, 1986 .

The relation of conductivity to the binding of thrombin to human platelets.

J. Miletich, P. Majerus, B. Rotoli, 1978, Thrombosis research.

t of Arteries , Veins , Capillaries , and Lymphatics , and on Syncytiotrophoblast of Human Placenta

C. Bell, P. Majerus, I. Maruyama, 2003 .

The 5-hydroxyl of myo-inositol is essential for uptake into HSDM1C1 mouse fibrosarcoma cells.

P. Majerus, R. Auchus, D. Covey, 1985, Biochemical and biophysical research communications.

Identification and isolation of a 75-kDa inositol polyphosphate-5-phosphatase from human platelets.

P. Majerus, C. Mitchell, T. Connolly, 1989, The Journal of biological chemistry.

Crystallization and initial X-ray crystallographic characterization of recombinant bovine inositol polyphosphate 1-phosphatase produced in Spodoptera frugiperda cells.

J. Ponder, J. York, Z. Chen, 1994, Journal of molecular biology.

The mRNA Export Factor Human Gle1 Interacts with the Nuclear Pore Complex Protein Nup155*

H. Rayala, P. Majerus, F. Kendirgi, 2004, Molecular & Cellular Proteomics.

Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase.

J. Hurley, P. Majerus, G. J. Miller, 2005, Molecular cell.

Inositol phosphate biochemistry.

P. Majerus, P W Majerus, 1992, Annual review of biochemistry.

Pathway for the formation of D-3 phosphate containing inositol phospholipids in PDGF stimulated NIH 3T3 fibroblasts.

P. Majerus, T. W. Cunningham, 1991, Biochemical and biophysical research communications.

A role for thrombomodulin in the pathogenesis of thrombin-induced thromboembolism in mice.

P. Majerus, W. Dittman, T. Kumada, 1988, Blood.

Editorial: Why aspirin?

P. Majerus, 1976, Circulation.

The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferation.

J. Krosl, P. Majerus, A. Miyajima, 1997, Leukemia.

Guanine nucleotides stimulate soluble phosphoinositide-specific phospholipase C in the absence of membranes.

P. Majerus, H. Deckmyn, S. Tu, 1986, The Journal of biological chemistry.

Protein C inhibits endocytosis of thrombin-thrombomodulin complexes in A549 lung cancer cells and human umbilical vein endothelial cells.

P. Majerus, I. Maruyama, 1987, Blood.

The light chain of factor Va contains the activity of factor Va that accelerates protein C activation by thrombin.

J. Miletich, P. Majerus, G. Broze, 1983, The Journal of biological chemistry.

Inositol polyphosphate 1-phosphatase from calf brain. Purification and inhibition by Li+, Ca2+, and Mn2+.

P. Majerus, R. Inhorn, 1987, The Journal of biological chemistry.

ACYL CARRIER PROTEIN. 3. AN ENOYL HYDRASE SPECIFIC FOR ACYL CARRIER PROTEIN THIOESTERS.

P. Majerus, A. Alberts, P. Vagelos, 1965, The Journal of biological chemistry.

Diverse proteins homologous to inositol monophosphatase

A. F. Neuwald, J. York, P. Majerus, 1991, FEBS letters.

Type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase regulates stress-induced apoptosis

P. Majerus, M. Kisseleva, Jasna A Marjanovic, 2007, Proceedings of the National Academy of Sciences.

Identification of a phosphodiesterase that converts inositol cyclic 1:2-phosphate to inositol 2-phosphate.

P. Majerus, T. Ross, 1992, Journal of Biological Chemistry.

Cyclic hydrolase-transfected 3T3 cells have low levels of inositol 1,2-cyclic phosphate and reach confluence at low density.

P. Majerus, T. Ross, R. A. Graham, 1991, Journal of Biological Chemistry.

Modulation of phosphatidylinositol-specific phospholipase C activity by phospholipid interactions, diglycerides, and calcium ions.

P. Majerus, P W Majerus, S. Hofmann, 1982, The Journal of biological chemistry.

Development and characterization of a tissue culture cell line with essential fatty acid deficiency.

P. Majerus, M. Laposata, S. Prescott, 1982, Proceedings of the National Academy of Sciences of the United States of America.

The interaction of human coagulation factor Va with platelets.

P. Majerus, W. Kane, P W Majerus, 1982, The Journal of biological chemistry.

The Metabolism of Inositol Phosphates

P. Majerus, R. Inhorn, H. Deckmyn, 1988 .

A Discrete Signaling Function for an Inositol Pyrophosphate

P. Majerus, 2007, Science's STKE.

Isolation and heterologous expression of a cDNA encoding bovine inositol polyphosphate 1-phosphatase.

J. York, P. Majerus, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Effects of thrombomodulin and coagulation Factor Va-light chain on protein C activation in vitro.

C. Esmon, P. Majerus, N. Esmon, 1984, The Journal of clinical investigation.

Isolation of Vitamin B , ,-binding Proteins Using Affinity Chromatography

P. Majerus, 2002 .

Association of androgenic-anabolic steroid therapy with development of hepatocellular carcinoma.

P. Majerus, M. Siegel, E. Thomas, 1972, Lancet.

Phosphatidylinositol signalling reactions.

P. Majerus, X Zhang, P W Majerus, 1998, Seminars in cell & developmental biology.

The cDNA Cloning and Characterization of Inositol Polyphosphate 4-Phosphatase Type II EVIDENCE FOR CONSERVED ALTERNATIVE SPLICING IN THE 4-PHOSPHATASE FAMILY*

R. Atkins, P. Majerus, F. Norris, 1997 .

Acetyl coenzyme A carboxylase. The effects of biotin deficiency on enzyme in rat liver and adipose tissue.

P. Majerus, E. Kilburn, R. Jacobs, 1970, The Journal of biological chemistry.

Isolation of 1-monomethylphosphoinositol 4,5-bisphosphate [a product of methanolysis of inositol 1,2-(cyclic)-4,5-trisphosphate] from Swiss mouse 3T3 cells.

P. Majerus, D. Lips, T. E. Bross, 1988, Proceedings of the National Academy of Sciences of the United States of America.

A mutant HSDM1C1 fibrosarcoma line selected for defective eicosanoid precursor uptake lacks arachidonate-specific acyl-CoA synthetase.

E. Neufeld, P. Majerus, T. E. Bross, 1984, The Journal of biological chemistry.

lmmunohistochemical Localization of Thrombomodulin in Chorionic Diseases of the Uterus and Choriocarcinorna of the Stomach A Comparative Study With the Distribution of Human Chorionic Gonadotropin

P. Majerus, I. Maruyama, S. Yonezawa, 2006 .

Diglyceride lipase: a pathway for arachidonate release from human platelets.

P. Majerus, D. Kennerly, R. Bell, 1980, Advances in prostaglandin and thromboxane research.

Isolation of D-myo-inositol 1:2-cyclic phosphate 2-inositolphosphohydrolase from human placenta.

P. Majerus, T. Ross, 1986, The Journal of biological chemistry.

[9] β-Ketoacyl acyl carrier protein synthase

P. Majerus, A. Alberts, P. Vagelos, 1969 .

Mechanisms for Eicosanoid Precursor Uptake and Release by a Tissue Culture Cell Line

E. Neufeld, P. Majerus, M. Laposata, 1985 .

Blasts from the past.

T. Stossel, A. Varki, P. Insel, 2004, The Journal of clinical investigation.

Properties of the factor Xa binding site on human platelets.

J. Miletich, P. Majerus, C. Jackson, 1978, The Journal of biological chemistry.

Properties of inositol polyphosphate 1-phosphatase.

P. Majerus, R. Inhorn, 1988, The Journal of biological chemistry.

Human thrombomodulin is not an efficient inhibitor of the procoagulant activity of thrombin.

P. Majerus, I. Maruyama, H. Ishii, 1985, The Journal of clinical investigation.