P. Madsen

发表

Structural basis for the recognition of carbohydrates by human galectin-7.

K. Acharya, D. Leonidas, E. Vatzaki, 1998, Biochemistry.

Transient Expression of cDNAs in COS-1 Cells: Protein Analysis by Two-Dimensional Gel Electrophoresis

J. Celis, P. Madsen, P. Gromov, 2006 .

Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing

J. Nyengaard, P. Madsen, T. Willnow, 2012, The Journal of Neuroscience.

Sortilin is essential for proNGF-induced neuronal cell death

Barbara L. Hempstead, Thomas E. Willnow, P. Madsen, 2004, Nature.

Labelling of Cells Engaged in DNA Synthesis: Autoradiography and BrdU Staining

P. Madsen, 2010 .

Expression of single-chain variable fragments fused with the Fc-region of rabbit IgG in Leishmania tarentolae

P. Madsen, P. Kristensen, M. Jørgensen, 2014, Microbial Cell Factories.

PAK Kinases Target Sortilin and Modulate Its Sorting

S. Thirup, P. Madsen, C. Petersen, 2019, Molecular and Cellular Biology.

Heterogeneous Nuclear Ribonucleoproteins H, H′, and F Are Members of a Ubiquitously Expressed Subfamily of Related but Distinct Proteins Encoded by Genes Mapping to Different Chromosomes *

N. Tommerup, B. Honoré, H. Vorum, 1995, The Journal of Biological Chemistry.

Molecular cloning and expression of a novel keratinocyte protein (psoriasis-associated fatty acid-binding protein [PA-FABP]) that is highly up-regulated in psoriatic skin and that shares similarity to fatty acid-binding proteins.

H. Leffers, B. Honoré, J. Celis, 1992, The Journal of investigative dermatology.

Molecular cloning and expression of a transformation-sensitive human protein containing the TPR motif and sharing identity to the stress-inducible yeast protein STI1.

H. Leffers, B. Honoré, J. Vandekerckhove, 1992, The Journal of biological chemistry.

Soluble SorCS1 binds the insulin receptor to enhance insulin sensitivity

T. Hansen, B. Holst, E. Füchtbauer, 2020, bioRxiv.

The C-terminal proteolytic processing of extracellular superoxide dismutase is redox regulated.

J. Enghild, P. Madsen, M. Nielsen, 2012, Free radical biology & medicine.

Nuclear patterns of cyclin (PCNA) antigen distribution subdivide S-phase in cultured cells--some applications of PCNA antibodies.

J. Celis, P. Madsen, S. Nielsen, 1986, Leukemia research.

Increased nuclear cyclin/PCNA antigen staining of non S‐phase transformed human amnion cells engaged in nucleotide excision DNA repair

J. Celis, P. Madsen, 1986, FEBS letters.

Cyclin (PCNA, auxiliary protein of DNA polymerase δ) is a central component of the pathway(s) leading to DNA replication and cell division

J. Celis, P. Madsen, B. Gesser, 1987, FEBS letters.

A novel approach for expression cloning of small GTPases: identification, tissue distribution and chromosome mapping of the human homolog of rheb

J. Celis, P. Madsen, P. Gromov, 1995, FEBS letters.

Human proteins IEF 58 and 57a are associated with the Golgi apparatus

J. Celis, P. Madsen, B. van Deurs, 1988, FEBS letters.

Interferon-gamma up-regulates a unique set of proteins in human keratinocytes. Molecular cloning and expression of the cDNA encoding the RGD-sequence-containing protein IGUP I-5111.

H. Leffers, B. Honoré, J. Celis, 1993, European journal of biochemistry.

The master two‐dimensional gel database of human AMA cell proteins: Towards linking protein and genome sequence and mapping information (Update 1991)

H. Leffers, B. Honoré, J. Vandekerckhove, 1991, Electrophoresis.

Nucleotide sequence of cDNA covering the complete coding part of the human vimentin gene.

H. Leffers, B. Honoré, J. Celis, 1990, Nucleic acids research.

Heparan sulfate proteoglycans present PCSK9 to the LDL receptor

S. Thirup, P. Madsen, P. Seeberger, 2017, Nature Communications.

Functional Organization of the Sortilin Vps10p Domain*

P. Madsen, E. S. Sørensen, A. Nykjær, 2004, Journal of Biological Chemistry.

The hypercholesterolemia-risk gene SORT1 facilitates PCSK9 secretion.

O. Mors, M. Nyegaard, M. Mattheisen, 2014, Cell metabolism.

Proneurotrophin‐3 may induce Sortilin‐dependent death in inner ear neurons

J. Nyengaard, T. Ovesen, P. Madsen, 2011, The European journal of neuroscience.

Polarized trafficking of the sorting receptor SorLA in neurons and MDCK cells

J. Bonifacino, P. Madsen, G. Olivecrona, 2016, The FEBS journal.

Heparan sulfate proteoglycans present PCSK9 to the LDL receptor

S. Thirup, P. Madsen, P. Seeberger, 2017, Nature Communications.

The human keratinocyte two‐dimensional protein database (update 1994): Towards an integrated approach to the study of cell proliferation, differentiation and skin diseases

H. Leffers, B. Honoré, J. Vandekerckhove, 1994, Electrophoresis.

Molecular Identification of a Novel Candidate Sorting Receptor Purified from Human Brain by Receptor-associated Protein Affinity Chromatography*

N. Tommerup, S. Moestrup, P. Madsen, 1997, The Journal of Biological Chemistry.

The Yeast Vps10p Cytoplasmic Tail Mediates Lysosomal Sorting in Mammalian Cells and Interacts with Human GGAs*

P. Madsen, M. Nielsen, C. Petersen, 2002, The Journal of Biological Chemistry.

The tetramethylammonium chloride method for screening of cDNA libraries using highly degenerate oligonucleotides obtained by backtranslation of amino-acid sequences.

H. Leffers, B. Honoré, P. Madsen, 1993, Journal of biochemical and biophysical methods.

DNA Synthesis: Autoradiography and BrdU Staining

P. Madsen, 2001 .

Characterization of sorCS1, an Alternatively Spliced Receptor with Completely Different Cytoplasmic Domains That Mediate Different Trafficking in Cells*

P. Madsen, J. Gliemann, C. Jacobsen, 2003, The Journal of Biological Chemistry.

Cell Cycle Dependent Variations in the Distribution of the Nuclear Protein Cyclin (Pcna) in Cultured Cells

J. Celis, P. Madsen, A. Celis, 1985 .

Cloning and sequencing of a human cDNA encoding a putative transcription factor containing a bromodomain.

P. Madsen, J. Gliemann, M. Nielsen, 1996, Biochimica et biophysica acta.

Oxidative folding of nerve growth factor can be mediated by the pro‐peptide of neurotrophin‐3

R. Rudolph, P. Madsen, Marco Kliemannel, 2007, FEBS letters.

The sorLA cytoplasmic domain interacts with GGA1 and ‐2 and defines minimum requirements for GGA binding

A. Smit, W. Geraerts, P. Madsen, 2002, FEBS letters.

Cytokine-Like Factor 1, an Essential Facilitator of Cardiotrophin-Like Cytokine:Ciliary Neurotrophic Factor Receptor α Signaling and sorLA-Mediated Turnover

P. Madsen, J. Bauer, M. Nielsen, 2016, Molecular and Cellular Biology.

S‐phase patterns of cyclin (PCNA) antigen staining resemble topographical patterns of DNA synthesis

J. Celis, P. Madsen, 1985, FEBS letters.

The carboxy‐terminal domain of the receptor‐associated protein binds to the Vps10p domain of sortilin

S. Moestrup, P. Madsen, L. Ellgaard, 1998, FEBS letters.

SorCS2 Regulates Dopaminergic Wiring and Is Processed into an Apoptotic Two-Chain Receptor in Peripheral Glia

G. Eichele, J. Nyengaard, E. Füchtbauer, 2014, Neuron.

Computerized, comprehensive databases of cellular and secreted proteins from normal human embryonic lung MRC‐5 fibroblasts: Identification of transformation and/or proliferation sensitive proteins

H. Leffers, B. Honoré, J. Celis, 1989, Electrophoresis.

Major proteins induced and down-regulated by interferons in human cultured cells: identification of a unique set of proteins induced by interferon-alpha in epithelial, fibroblast, and lymphoid cells.

J. Lovmand, J. Celis, P. Madsen, 1987, Leukemia.

Levels of synthesis of primate-specific nuclear proteins differ between growth-arrested and proliferating cells.

J. Celis, P. Madsen, S. Nielsen, 1987, Experimental cell research.

Cleaved intracellular plasminogen activator inhibitor 2 in human myeloleukaemia cells is a marker of apoptosis.

M. Lanotte, S. Døskeland, G. Mellgren, 1994, British Journal of Cancer.

Sortilin is a putative postendocytic receptor of thyroglobulin.

C. Marcocci, A. Pinchera, A. Fausto, 2009, Endocrinology.

Mapping of the Interaction Site between Sortilin and the p75 Neurotrophin Receptor Reveals a Regulatory Role for the Sortilin Intracellular Domain in p75 Neurotrophin Receptor Shedding and Apoptosis*

E. Castrén, P. Madsen, D. Matusica, 2012, The Journal of Biological Chemistry.

The human keratinocyte two‐dimensional gel protein database (update 1992): Towards an integrated approach to the study of cell proliferation, differentiation and skin diseases

Joël Vandekerckhove, H. Leffers, B. Honoré, 1992, Electrophoresis.

Towards establishing comprehensive databases of cellular proteins from transformed human epithelial amnion cells (AMA) and normal peripheral blood mononuclear cells.

J. Celis, P. Madsen, B. Gesser, 1988, Leukemia.

SorCS3 does not require propeptide cleavage to bind nerve growth factor

P. Madsen, E. S. Sørensen, C. M. Petersen, 2005, FEBS letters.

Psoriasis upregulated phorbolin-1 shares structural but not functional similarity to the mRNA-editing protein apobec-1.

I. Dunham, N. Tommerup, J. Dumanski, 1999, The Journal of investigative dermatology.

Anti‐mitochondrial protein antibodies in a serum from a patient with systemic lupus erythematosus: Specificity and comparison with other anti‐mitochondrial antibodies

J. Celis, P. Madsen, J. Vayssière, 1987 .

Cyclin/PCNA is a cell cycle modulated nuclear protein with a role in DNA replication.

J. Celis, P. Madsen, B. Gesser, 1988, Archivos de biologia y medicina experimentales.

Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export.

P. Madsen, T. Willnow, J. Heeren, 2010, Cell metabolism.

Molecular cloning and expression of the transformation sensitive epithelial marker stratifin. A member of a protein family that has been involved in the protein kinase C signalling pathway.

J Vandekerckhove, H. Leffers, B. Honoré, 1993, Journal of molecular biology.

Ligands bind to Sortilin in the tunnel of a ten-bladed β-propeller domain

P. Nissen, S. Thirup, P. Madsen, 2009, Nature Structural &Molecular Biology.

The sortilin cytoplasmic tail conveys Golgi–endosome transport and binds the VHS domain of the GGA2 sorting protein

P. Madsen, E. Christensen, A. Nykjær, 2001, The EMBO journal.

Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin

P. Nissen, S. Thirup, P. Madsen, 2014, Protein science : a publication of the Protein Society.

Propeptide cleavage conditions sortilin/neurotensin receptor‐3 for ligand binding

S. Moestrup, P. Madsen, J. Gliemann, 1999, The EMBO journal.

Sortilin and SorLA Display Distinct Roles in Processing and Trafficking of Amyloid Precursor Protein

P. Madsen, O. Andersen, A. Nykjær, 2013, The Journal of Neuroscience.

GGA Autoinhibition Revisited

S. Thirup, P. Madsen, M. Behrens, 2010, Traffic.

Different Motifs Regulate Trafficking of SorCS1 Isoforms

Dietmar Kuhl, P. Madsen, A. Engelsberg, 2008, Traffic.

Monoclonal antibody specific for human nuclear proteins IEF 8Z30 and 8Z31 accumulates in the nucleus a few hours after cytoplasmic microinjection of cells expressing these proteins

J. Celis, P. Madsen, S. Nielsen, 1986, Journal of Cell Biology.

Identification, molecular cloning, expression and chromosome mapping of a family of transformation upregulated hnRNP-K proteins derived by alternative splicing.

H. Leffers, J. Celis, P. Madsen, 1994, Journal of molecular biology.

Molecular Characterization of a Novel Human Hybrid-type Receptor That Binds the α2-Macroglobulin Receptor-associated Protein*

N. Tommerup, S. Moestrup, P. Madsen, 1996, The Journal of Biological Chemistry.

Psoriasin: a novel chemotactic protein.

B. Honoré, H. Vorum, J. Celis, 1996, The Journal of investigative dermatology.

Bladder squamous cell carcinomas express psoriasin and externalize it to the urine.

B. Honoré, H. Vorum, J. Celis, 1996, The Journal of urology.

Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly up-regulated in psoriatic skin.

H. Leffers, B. Honoré, P. Madsen, 1991, The Journal of investigative dermatology.

SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.

J. Nyengaard, M. Saarma, C. Vaegter, 2013, Cell reports.

Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease

M. Nyegaard, G. Halliday, T. Andresen, 2016, PloS one.

The MRC‐5 human embryonal lung fibroblast two‐dimensional gel cellular protein database: Quantitative identification of polypeptides whose relative abundance differs between quiescent, proliferating and SV 40 transformed cells

H. Leffers, B. Honoré, J. Vandekerckhove, 1990, Electrophoresis.

The human keratinocyte two‐dimensional gel protein database: Update 1993

H. Leffers, B. Honoré, J. Vandekerckhove, 1993, Electrophoresis.

A comprehensive two‐dimensional gel protein database of noncultured unfractionated normal human epidermal keratinocytes: Towards an integrated approach to the study of cell proliferation, differentiation and skin diseases

P. S. Pedersen, H. Leffers, B. Honoré, 1991, Electrophoresis.

Refined mapping of the psoriasin gene S100A7 to chromosome 1cen-q21

A. Børglum, J. Celis, P. Madsen, 1995, Human Genetics.

The Endo-Lysosomal System of Brain Endothelial Cells Is Influenced by Astrocytes In Vitro

L. B. Thomsen, P. Madsen, H. Lohi, 2018, Molecular Neurobiology.

Comprehensive, human cellular protein databases and their implication for the study of genome organization and function

H. Leffers, B. Honoré, J. Vandekerckhove, 1989, FEBS letters.

Human 2‐D PAGE databases for proteome analysis in health and disease: http ://biobase.dk/cgi‐bin/celis

Morten Østergaard, Henrik Vorum, D. B. Kristensen, 1996, FEBS letters.

Human cellular protein patterns and their link to genome DNA mapping and sequencing data: towards an integrated approach to the study of gene expression.

H. Leffers, B. Honoré, J. Vandekerckhove, 1993, Genetic engineering.

Comprehensive two‐dimensional gel protein databases offer a global approach to the analysis of human cells: The transformed amnion cells (AMA) master database and its link to genome DNA sequence data

Joël Vandekerckhove, Guy Bauw, H. Leffers, 1990, Electrophoresis.

Two dimensional gel human protein databases offer a systematic approach to the study of cell proliferation and differentiation.

H. Leffers, B. Honoré, J. Celis, 1989, The International journal of developmental biology.

The human keratinocyte two‐dimensional gel protein database (update 1995): Mapping components of signal transduction pathways

Morten Østergaard, Henrik Vorum, H. Leffers, 1995, Electrophoresis.

Interferon‐α‐induced changes in surface antigens in a hairy‐cell leukemia (JOK‐1)‘ and a Burkitt's lymphoma cell line (Daudi) during in vitro culture

P. Madsen, P. Hokland, A. W. Jensen, 1992, European journal of haematology.

Cloning, Expression, and Chromosome Mapping of Human Galectin-7 (*)

B. Honoré, H. Vorum, J. Celis, 1995, The Journal of Biological Chemistry.

Acidic Environment Induces Dimerization and Ligand Binding Site Collapse in the Vps10p Domain of Sortilin.

S. Thirup, D. Januliene, A. Moeller, 2017, Structure.

Sorting by the Cytoplasmic Domain of the Amyloid Precursor Protein Binding Receptor SorLA

J. Nyengaard, P. Madsen, O. Bakke, 2007, Molecular and Cellular Biology.

EF-hands at atomic resolution: the structure of human psoriasin (S100A7) solved by MAD phasing.

J. Nyborg, M. Kjeldgaard, D. Brodersen, 1998, Structure.

Psoriasin binds calcium and is upregulated by calcium to levels that resemble those observed in normal skin.

J. Celis, P. Madsen, M. Etzerodt, 1994, The Journal of investigative dermatology.

Expression of recombinant psoriasis‐associated fatty acid binding protein in Escherichia coli: Gel electrophoretic characterization, analysis of binding properties and comparison with human serum albumin

B. Honoré, H. Vorum, J. Celis, 1998, Electrophoresis.

cDNA expression and human two‐dimensional gel protein databases: Towards integrating DNA and protein information

H. Leffers, B. Honoré, J. Celis, 1996, Electrophoresis.

Expression of cyclin (PCNA) and the phosphoprotein dividin are late obligatory events in the mitogenic response.

J. Celis, P. Madsen, H. Rasmussen, 1987, Anticancer research.

Molecular cloning of a cDNA encoding human calumenin, expression in Escherichia coli and analysis of its Ca2+-binding activity.

B. Honoré, H. Vorum, P. Madsen, 1998, Biochimica et biophysica acta.

PCSK9 deficiency alters brain lipid composition without affecting brain development and function

V. Tarabykin, P. Madsen, T. Timmusk, 2023, Frontiers in Molecular Neuroscience.

Identification of two human Rho GDP dissociation inhibitor proteins whose overexpression leads to disruption of the actin cytoskeleton.

J Vandekerckhove, H. Leffers, B. Honoré, 1993, Experimental cell research.

Contents to volume 220

J. Celis, P. Madsen, A. Tanaka, 2001 .

Heparan sulfate proteoglycans present PCSK9 to the LDL receptor

S. Thirup, P. Madsen, P. Seeberger, 2017, Nature Communications.

HSPA12A targets the cytoplasmic domain and affects the trafficking of the Amyloid Precursor Protein receptor SorLA

M. Nyegaard, P. Madsen, M. Nielsen, 2019, Scientific Reports.

Random Uptake Conditions the Hit-and-run Method High-flux Backbone

P. Madsen, K. Teng, B. Hempstead, 2022 .

Activation and Functional Characterization of the Mosaic Receptor SorLA/LR11*

P. Madsen, J. Gliemann, C. Jacobsen, 2001, The Journal of Biological Chemistry.

p25α Stimulates α-Synuclein Aggregation and Is Co-localized with Aggregated α-Synuclein in α-Synucleinopathies*

Daniel Otzen, P. Højrup, J. Nyengaard, 2005, Journal of Biological Chemistry.

Cloning of a cDNA encoding a novel human nuclear phosphoprotein belonging to the WD-40 family.

H. Leffers, B. Honoré, J. Celis, 1994, Gene.

Cloning and expression of a cDNA covering the complete coding region of the P32 subunit of human pre-mRNA splicing factor SF2.

H. Leffers, B. Honoré, J. Vandekerckhove, 1993, Gene.

Sortilin Facilitates Signaling of Ciliary Neurotrophic Factor and Related Helical Type 1 Cytokines Targeting the gp130/Leukemia Inhibitory Factor Receptor β Heterodimer

J. Scheller, P. Madsen, M. Nielsen, 2010, Molecular and Cellular Biology.

Increased phosphorylation of elongation factor 2 during mitosis in transformed human amnion cells correlates with a decreased rate of protein synthesis.

J. Celis, P. Madsen, A. Ryazanov, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Proprotein convertase subtilisin/kexin type 9 targets megalin in the kidney proximal tubule and aggravates proteinuria in nephrotic syndrome.

P. Madsen, P. Ivarsen, H. Birn, 2023, Kidney international.

Alternative splicing regulates adaptor protein binding, trafficking, and activity of the Vps10p domain receptor SorCS2 in neuronal development

P. Madsen, H. Buttenschøn, Perline A. Demange, 2023, The Journal of biological chemistry.

Endothelial cells of the human microvasculature express epidermal fatty acid-binding protein.

J. Saurat, P. Madsen, M. Pepper, 1997, Circulation research.

Epitope mapping of nanobodies binding the Alzheimer's disease receptor SORLA.

S. Muyldermans, P. Madsen, C. Vincke, 2023, Journal of Biotechnology.

The hypercholesterolemia-risk gene SORT1 facilitates PCSK9 secretion.

O. Mors, M. Nyegaard, M. Mattheisen, 2014, Cell metabolism.

SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.

J. Nyengaard, M. Saarma, C. Vaegter, 2013, Cell reports.

Different Motifs Regulate Trafficking of SorCS1 Isoforms

Dietmar Kuhl, P. Madsen, A. Engelsberg, 2008, Traffic.

Human sorCS1 binds sortilin and hampers its cellular functions.

P. Madsen, E. Christensen, E. S. Sørensen, 2014, The Biochemical journal.

associated with the Golgi

B. Deurs, J. Celis, P. Madsen, 1988 .