D. Beste

发表

Systems Biology of Tuberculosis

A. Kierzek, J. McFadden, D. Beste, 2013, Springer New York.

GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism

S. Klamt, A. Kierzek, B. Bonde, 2007, Genome Biology.

Systems biology of the metabolism of Mycobacterium tuberculosis.

J. McFadden, D. Beste, 2010, Biochemical Society transactions.

Metabolism of Mycobacterium tuberculosis

J. McFadden, D. Beste, 2013 .

System-level strategies for studying the metabolism of Mycobacterium tuberculosis

J. McFadden, D. Beste, 2010, Molecular bioSystems.

A systematic evaluation of Mycobacterium tuberculosis Genome-Scale Metabolic Networks

Víctor A. López-Agudelo, Rigoberto Ríos-Estepa, D. Beste, 2020, PLoS computational biology.

Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis

J. Sacchettini, I. Krieger, A. Steyn, 2020, Nature Communications.

Metabolic fluxes for nutritional flexibility of Mycobacterium tuberculosis

V. T. Forsyth, S. Noack, J. McFadden, 2021, Molecular systems biology.

Metabolic flux partitioning between the TCA cycle and glyoxylate shunt combined with a reversible methyl citrate cycle provide nutritional flexibility for Mycobacterium tuberculosis

V. T. Forsyth, J. McFadden, Nathaniel D Hawkins, 2021, bioRxiv.

Intracellular Mycobacterium tuberculosis Exploits Multiple Host Nitrogen Sources during Growth in Human Macrophages

J. McFadden, D. Beste, A. Theorell, 2019, Cell reports.

A mixed nitrogen diet and compartmentalized utilization for Mycobacterium tuberculosis replicating in host cells: results of a systems-based analysis

J. McFadden, D. Beste, K. Nöh, 2019, bioRxiv.

Title: THE GENETIC REQUIREMENTS FOR FAST AND SLOW GROWTH IN MYCOBACTERIA Running head. Mycobacterial genes required for growth rate control Authors and Affiliations

A. Kierzek, B. Bonde, D. Beste, 2011 .

Systems-Based Approaches to Probing Metabolic Variation within the Mycobacterium tuberculosis Complex

Andrzej M. Kierzek, Paul R. Wheeler, Johnjoe McFadden, 2013, PloS one.

Structural and molecular dynamics of Mycobacterium tuberculosis malic enzyme, a potential anti-TB drug target

D. Mobley, C. Goulding, D. Beste, 2020, bioRxiv.

13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation

S. Noack, B. Bonde, J. McFadden, 2011, PLoS pathogens.

The Genetic Requirements for Fast and Slow Growth in Mycobacteria

A. Kierzek, B. Bonde, J. McFadden, 2009, PloS one.

Compiling a Molecular Inventory for Mycobacterium bovis BCG at Two Growth Rates: Evidence for Growth Rate-Mediated Regulation of Ribosome Biosynthesis and Lipid Metabolism

J. McFadden, C. Avignone-Rossa, M. Bushell, 2005, Journal of bacteriology.

Differential Producibility Analysis (DPA) of Transcriptomic Data with Metabolic Networks: Deconstructing the Metabolic Response of M. tuberculosis

Andrzej M. Kierzek, Emma Laing, Bhushan K. Bonde, 2011, PLoS Comput. Biol..

Murine Norovirus Infection Results in Anti-inflammatory Response Downstream of Amino Acid Depletion in Macrophages

D. Beste, B. Hall, I. Goodfellow, 2021, Journal of virology.

Dual RNA Sequencing of Mycobacterium tuberculosis-Infected Human Splenic Macrophages Reveals a Strain-Dependent Host–Pathogen Response to Infection

Víctor A. López-Agudelo, Rigoberto Ríos-Estepa, D. Beste, 2022, International journal of molecular sciences.

A systematic evaluation of Mycobacterium tuberculosis Genome-Scale Metabolic Networks

Emma Laing, Víctor A. López-Agudelo, Tom A. Mendum, 2019, bioRxiv.

Transcriptomic Analysis Identifies Growth Rate Modulation as a Component of the Adaptation of Mycobacteria to Survival inside the Macrophage

B. Bonde, J. McFadden, C. Avignone-Rossa, 2007, Journal of bacteriology.

The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis

J. McFadden, D. Beste, J. Ward, 2018, The Journal of Biological Chemistry.

13C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis

Wolfgang Wiechert, Katharina Nöh, Sebastian Niedenführ, 2013, Chemistry & biology.

Intracellular Mycobacterium leprae Utilizes Host Glucose as a Carbon Source in Schwann Cells

J. McFadden, D. Beste, M. C. Pessolani, 2019, mBio.

Expanding the boundaries of atomic spectroscopy at the single-cell level: critical review of SP-ICP-MS, LIBS and LA-ICP-MS advances for the elemental analysis of tissues and single cells

Michael C. Bailey, M. Felipe-Sotelo, D. Beste, 2023, Analytical and Bioanalytical Chemistry.

One‐shot 13C15N‐metabolic flux analysis for simultaneous quantification of carbon and nitrogen flux

Michael C. Bailey, J. McFadden, D. Beste, 2023, Molecular systems biology.

Bayesian multi-model-based 13C15N-metabolic flux analysis quantifies carbon-nitrogen metabolism in mycobacteria

J. McFadden, D. Beste, K. Nöh, 2022, bioRxiv.

Murine Norovirus infection results in anti-inflammatory response downstream of amino acids depletion in macrophages

D. Beste, B. Hall, I. Goodfellow, 2021, bioRxiv.

13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation

S. Noack, B. Bonde, J. McFadden, 2011, PLoS pathogens.

Spatial single cell metabolomics: Current challenges and future developments.

Michael C. Bailey, D. Beste, O. Cexus, 2023, Current opinion in chemical biology.

GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism

A. Kierzek, B. Bonde, P. Wheeler, 2007, Genome Biology.