V. Helms

Volkhard Helms, Duy Nguyen, Mathias Herrmann, 2015, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

Putative cholesterol‐binding sites in human immunodeficiency virus (HIV) coreceptors CXCR4 and CCR5

V. Helms, M. Zhukovsky, Po-Hsien Lee, 2013, Proteins.

Proteomics Identifies Substrates and a Novel Component in hSnd2-Dependent ER Protein Targeting

F. Förster, S. High, V. Helms, 2022, bioRxiv.

Analysis of the dynamics of Staphylococcus aureus binding to white blood cells using whole blood assay and geno-to-pheno mapping.

V. Helms, Ruslan Akulenko, M. Herrmann, 2020, International journal of medical microbiology : IJMM.

The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma

Marcel H. Schulz, P. Blackshear, V. Helms, 2019, Cancers.

Protein–protein docking of electron transfer complexes: Cytochrome c oxidase and cytochrome c

V. Helms, D. Flöck, 2002, Proteins.

Kinase conformations: A computational study of the effect of ligand binding

J. Mccammon, V. Helms, J. McCammon, 1997, Protein science : a publication of the Protein Society.

Dynamic water networks in cytochrome C oxidase from Paracoccus denitrificans investigated by molecular dynamics simulations.

H. Michel, M. Lill, V. Helms, 2004, Biophysical journal.

Is the proteomic composition of the salivary pellicle dependent on the substrate material?

V. Flockerzi, V. Helms, C. Fecher-Trost, 2022, Proteomics. Clinical applications.

How Peptides Bind to PSD-95/Discs-Large/ZO-1 Domains.

V. Helms, Nicolas Künzel, 2022, Journal of chemical theory and computation.

TopControl: A Tool to Prioritize Candidate Disease-associated Genes based on Topological Network Features

V. Helms, Maryam Nazarieh, 2019, Scientific Reports.

2017A Schultheiss Cell Stress

Marcel H. Schulz, F. Lammert, R. Bohle, 2017 .

The long non-coding RNA H19 suppresses carcinogenesis and chemoresistance in hepatocellular carcinoma

Marcel H. Schulz, F. Lammert, R. Bohle, 2017, Cell stress.

AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum

A. Cavalié, I. Haferkamp, V. Helms, 2018, Nature Communications.

Interorganelle Tethering to Endocytic Organelles Determines Directional Cytokine Transport in CD4+ T Cells

R. Akbar, H. Rieger, V. Helms, 2020, The Journal of Immunology.

Mycolactone enhances the Ca leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca permeable state

A. Cavalié, V. Helms, B. Hall, 2021 .

Mycolactone enhances the Ca2+ leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state

A. Cavalié, V. Helms, B. Hall, 2021, bioRxiv.

Design of a gated molecular proton channel.

Haiping Fang, V. Helms, W. Gu, 2011, Angewandte Chemie.

Thermodynamics of water mediating protein-ligand interactions in cytochrome P450cam: a molecular dynamics study.

R. Wade, V. Helms, Volkhard Helms, 1995, Biophysical journal.

Signal Peptide Features Determining the Substrate Specificities of Targeting and Translocation Components in Human ER Protein Import

V. Helms, M. Jung, R. Zimmermann, 2022, Frontiers in Physiology.

Specific and non-specific effects of potassium cations on substrate-protein interactions in cytochromes P450cam and P450lin.

R. Wade, E. Deprez, V. Helms, 2002, Journal of inorganic biochemistry.

PEX19 Coordinates Neutral Lipid Storage in Cells in a Peroxisome-Independent Fashion

V. Helms, T. Hartmann, R. Kopito, 2022, Frontiers in Cell and Developmental Biology.

IGF2 mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis

J. Walter, I. Leclercq, J. Hengstler, 2019, Front. Med..

Towards Understanding the Early Events in the Conformational Transition of Amyloid Beta Peptides

S. Mohanty, W. Nadler, V. Helms, 2008 .

Linking Hematopoietic Differentiation to Co-Expressed Sets of Pluripotency-Associated and Imprinted Genes and to Regulatory microRNA-Transcription Factor Motifs

John R Trumm, G. Fuellen, V. Helms, 2017, PloS one.

Contribution of charged and polar residues for the formation of the E1–E2 heterodimer from Hepatitis C Virus

R. Böckmann, V. Helms, S. Siu, 2010, Journal of molecular modeling.

Elevated expression of the IGF2 mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinoma

V. Helms, J. Haybaeck, N. Golob-Schwarzl, 2016, Oncotarget.

Detecting Staphylococcus aureus Virulence and Resistance Genes: a Comparison of Whole-Genome Sequencing and DNA Microarray Technology

Volkhard Helms, Georg Peters, Marcelino Garrine, 2016, Journal of Clinical Microbiology.

The ER protein translocation channel subunit Sbh1 controls virulence of Cryptococcus neoformans

T. Doering, V. Helms, J. Geddes-McAlister, 2022, bioRxiv.

Quantitative Proteomics and Differential Protein Abundance Analysis after the Depletion of PEX3 from Human Cells Identifies Additional Aspects of Protein Targeting to the ER

F. Förster, V. Helms, R. Zimmermann, 2021, International journal of molecular sciences.

Development of a high-throughput screening-compatible assay to identify inhibitors of the CK2α/CK2β interaction.

C. Götz, O. Issinger, V. Helms, 2015, Analytical biochemistry.

Identification of molecular candidates which regulate calcium-dependent CD8+ T-cell cytotoxicity

V. Helms, M. Hamed, E. Meese, 2020, bioRxiv.

Hepatic hepcidin expression is decreased in cirrhosis and HCC.

V. Helms, A. Kiemer, S. Kessler, 2015, Journal of hepatology.

Internal Dynamics of Green Fluorescent Protein

T. Straatsma, J. Mccammon, V. Helms, 1999 .

ER translocation of suboptimal targeting sequences depends on Sec61β/Sbh1 and its phosphorylation

M. Schuldiner, V. Helms, H. Meyer, 2022, bioRxiv.

Faculty Opinions recommendation of Chi(1) rotamer populations and angles of mobile surface side chains are accurately predicted by a torsion angle database potential of mean force.

V. Helms, 2002 .

Tightly connected water wires facilitate fast proton uptake at the proton entrance of proton pumping proteins.

V. Helms, W. Gu, 2009, Journal of the American Chemical Society.

A Methylation-Directed, Synthetic Pap Switch Based on Self-Complementary Regulatory DNA in an All-E. Coli Cell-Free Expression System

V. Noireaux, V. Helms, A. Ott, 2020 .

Polyamines: naturally occurring small molecule modulators of electrostatic protein-protein interactions.

V. Helms, Susanne Eyrisch, I. Schuster, 2010, Journal of inorganic biochemistry.

A Methylation-Directed, Synthetic Pap Switch Based on Self-Complementary Regulatory DNA Reconstituted in an All E. coli Cell-Free Expression System.

V. Noireaux, V. Helms, A. Ott, 2021, ACS synthetic biology.

Expression regulation by a methyl-CpG binding domain in an E. coli based, cell-free TX-TL system

V. Noireaux, V. Helms, A. Ott, 2017, Physical biology.

The mechanism of proton exclusion in the aquaporin-1 water channel.

B. L. de Groot, H. Grubmüller, V. Helms, 2003, Journal of molecular biology.

Deep Proteomic Insights into the Individual Short‐Term Pellicle Formation on Enamel—An In Situ Pilot Study

V. Helms, C. Fecher-Trost, M. Hannig, 2020, Proteomics. Clinical applications.

Proteomic Analysis of the Initial Oral Pellicle in Caries‐Active and Caries‐Free Individuals

V. Helms, C. Hannig, C. Fecher-Trost, 2019, Proteomics. Clinical applications.

Community-Associated Staphylococcus aureus from Sub-Saharan Africa and Germany: A Cross-Sectional Geographic Correlation Study

M. Tanner, A. Mellmann, P. Kremsner, 2017, Scientific Reports.

Hydration energy landscape of the active site cavity in cytochrome P450cam

R C Wade, R. Wade, V. Helms, 1998, Proteins.

A longer isoform of Stim1 is a negative SOCE regulator but increases cAMP‐modulated NFAT signaling

V. Helms, T. Mühlhaus, Frederik Sommer, 2021, EMBO reports.

Prediction of Synergistic Toxicity of Binary Mixtures to Vibrio fischeri Based on Biomolecular Interaction Networks.

V. Helms, Jongwoon Kim, Max Fischer, 2018, Chemical research in toxicology.

Protein transport into the human endoplasmic reticulum.

F. Förster, A. Cavalié, V. Helms, 2015, Journal of molecular biology.

Regulation of Fe DEFICIENCY INDUCED TRANSCRIPTION FACTOR ( FIT ) protein abundance in response to ethylene and nitric oxide

V. Helms, 2013 .

Hydrogen-bonded networks along and bifurcation of the E-pathway in quinol:fumarate reductase.

W. Mäntele, V. Helms, C. Lancaster, 2012, Biophysical journal.

Reconstruction of a kinetic model of the chromatophore vesicles from Rhodobacter sphaeroides.

V. Helms, T. Geyer, 2006, Biophysical journal.

Deep Proteomic Insights into the Individual Short-Term Pellicle Formation on Enamel-An In Situ Pilot Study.

V. Helms, C. Fecher-Trost, M. Hannig, 2020, PROTEOMICS - Clinical Applications.

NWChem: Past, present, and future.

Jeffery S. Boschen, Nicholas P. Bauman, T. Straatsma, 2020, The Journal of chemical physics.

Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca2+ Leakage from the Endoplasmic Reticulum

S. High, A. Cavalié, V. Helms, 2019, Cell chemical biology.

The Mechanism of Phosphorylation of Natural Nucleosides and Anti‐HIV Analogues by Nucleoside Diphosphate Kinase Is Independent of Their Sugar Substituents

V. Helms, M. Hutter, 2002, Chembiochem : a European journal of chemical biology.

Rewiring of the inferred protein interactome during blood development studied with the tool PPICompare

Volkhard Helms, Thorsten Will, V. Helms, 2017, BMC Systems Biology.

SNP and indel frequencies at transcription start sites and at canonical and alternative translation initiation sites in the human genome

T. Marschall, V. Helms, Kerstin Neininger, 2019, PloS one.

DNA methylation and the core pluripotency network.

V. Helms, S. Shanak, Siba Shanak, 2020, Developmental biology.

Identification of novel diabetes impaired miRNA-transcription factor co-regulatory networks in bone marrow-derived Lin-/VEGF-R2+ endothelial progenitor cells

M. Gillies, V. Helms, M. Hamed, 2018, PloS one.

Low-lying electronic excitations of the green fluorescent protein chromophore

Volkhard Helms, P. W. Langhoff, V. Helms, 2000 .

Shedding light on the dark and weakly fluorescent states of green fluorescent proteins.

J A McCammon, P. W. Langhoff, J. Mccammon, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Imprinted genes show unique patterns of sequence conservation

B. Hutter, V. Helms, M. Bieg, 2010, BMC Genomics.

BEclear: Batch Effect Detection and Adjustment in DNA Methylation Data

Volkhard Helms, Ruslan Akulenko, Markus Merl, 2016, PloS one.

Topology Consistency of Disease-specific Differential Co-regulatory Networks

Volkhard Helms, Hema Sekhar Reddy Rajula, Maryam Nazarieh, 2019, BMC Bioinformatics.

ERAD and protein import defects in a sec61 mutant lacking ER-lumenal loop 7

K. Kalies, V. Helms, Ozlem Ulucan, 2013, BMC Cell Biology.

Endothelial and epithelial differentiation potential of human adult stem cells PSC and MSC and the relation of ZO-1 isoform ratio to epithelial differentiation in Caco-2

V. Helms, I. Bernhardt, A. Kiemer, 2013 .

Differential analysis of combinatorial protein complexes with CompleXChange

V. Helms, Thorsten Will, 2019, BMC Bioinformatics.

Identifying transcription factor complexes and their roles

Volkhard Helms, Thorsten Will, V. Helms, 2014, Bioinform..

AKSmooth: Enhancing low-coverage bisulfite sequencing data via kernel-based smoothing

Volkhard Helms, Junfang Chen, Pavlo Lutsik, 2014, J. Bioinform. Comput. Biol..

MutaNET: a tool for automated analysis of genomic mutations in gene regulatory networks

Volkhard Helms, Markus Hollander, Mohamed Hamed, 2017, Bioinform..

Integrative network-based approach identifies key genetic elements in breast invasive carcinoma

Volkhard Helms, Christian Spaniol, Mohamed Hamed, 2015, BMC Genomics.

Titration behavior of residues at the entrance of the D-pathway of cytochrome c oxidase from paracoccus denitrificans investigated by continuum electrostatic calculations.

H. Michel, V. Helms, E. Olkhova, 2005, Biophysical journal.

What induces pocket openings on protein surface patches involved in protein–protein interactions?

Volkhard Helms, Susanne Eyrisch, V. Helms, 2009, J. Comput. Aided Mol. Des..

Novel scoring function for modeling structures of oligomers of transmembrane α‐helices

Yungki Park, Volkhard Helms, V. Helms, 2004 .

Cellular Functions of Genetically Imprinted Genes in Human and Mouse as Annotated in the Gene Ontology

V. Helms, M. Hamed, M. Paulsen, 2012, PloS one.

Prediction of the burial status of transmembrane residues of helical membrane proteins

Yungki Park, Volkhard Helms, Sikander Hayat, 2007, BMC Bioinformatics.

On the derivation of propensity scales for predicting exposed transmembrane residues of helical membrane proteins

Yungki Park, Volkhard Helms, V. Helms, 2007, Bioinform..

Interaction of calmodulin with Sec61α limits Ca2+ leakage from the endoplasmic reticulum

A. Cavalié, Mazen Ahmad, V. Helms, 2011, The EMBO journal.

Overexpression of IGF2 mRNA‐Binding Protein 2 (IMP2/p62) as a Feature of Basal‐like Breast Cancer Correlates with Short Survival

V. Helms, S. Kessler, A. Barghash, 2015, Scandinavian journal of immunology.

Human profilin 1 is a negative regulator of CTL mediated cell‐killing and migration

Arne Knörck, V. Helms, M. Hamed, 2017, European journal of immunology.

Phenylbutyrate rescues the transport defect of the Sec61α mutations V67G and T185A for renin

A. Cavalié, K. Hodaňová, V. Helms, 2022, Life Science Alliance.

An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases

F. Förster, A. Cavalié, V. Helms, 2017, Front. Physiol..

Dynamical binding of proline-rich peptides to their recognition domains.

V. Helms, W. Gu, 2005, Biochimica et biophysica acta.

Alternative binding modes of proline-rich peptides binding to the GYF domain.

V. Helms, C. Freund, I. Antes, 2005, Biochemistry.

Community-Associated Staphylococcus aureus from Sub-Saharan Africa and Germany: A Cross-Sectional Geographic Correlation Study

M. Tanner, A. Mellmann, P. Kremsner, 2017, Scientific Reports.

Detecting Rewiring Events in Protein-Protein Interaction Networks Based on Transcriptomic Data

V. Helms, T. Do, Markus Hollander, 2021, Frontiers in Bioinformatics.

PreTIS: A Tool to Predict Non-canonical 5’ UTR Translational Initiation Sites in Human and Mouse

Volkhard Helms, Kerstin Reuter, Alexander Biehl, 2016, PLoS Comput. Biol..

Fatty Acid Elongation in Non-Alcoholic Steatohepatitis and Hepatocellular Carcinoma

F. Lammert, R. Bohle, J. Hengstler, 2014, International journal of molecular sciences.

Regulatory network characterization in development: challenges and opportunities

J. Han, V. Helms, Guangdun Peng, 2018, F1000Research.

Sec61 channel subunit Sbh1/Sec61β promotes ER translocation of proteins with suboptimal targeting sequences and is fine-tuned by phosphorylation

M. Schuldiner, V. Helms, H. Meyer, 2023, The Journal of biological chemistry.

ProPores2: Web Service and Stand-Alone Tool for Identifying, Manipulating, and Visualizing Pores in Protein Structures

Volkhard Helms, Markus Hollander, David J. N. P. Rasp, 2021, J. Chem. Inf. Model..

Divergence of imprinted genes during mammalian evolution

B. Hutter, V. Helms, M. Bieg, 2010, BMC Evolutionary Biology.

Redox signals at the ER–mitochondria interface control melanoma progression

Jan Dudek, P. Rehling, V. Helms, 2019, The EMBO journal.

Functions and Mechanisms of the Human Ribosome-Translocon Complex.

F. Förster, V. Helms, R. Zimmermann, 2019, Sub-cellular biochemistry.

Protein Signatures of NK Cell–Mediated Melanoma Killing Predict Response to Immunotherapies

M. Herlyn, P. Rehling, V. Helms, 2021, Cancer Research.

Quantitative Proteomics and Differential Protein Abundance Analysis after Depletion of Putative mRNA Receptors in the ER Membrane of Human Cells Identifies Novel Aspects of mRNA Targeting to the ER

F. Förster, V. Helms, R. Zimmermann, 2021, Molecules.

PPIXpress: construction of condition-specific protein interaction networks based on transcript expression

Volkhard Helms, Thorsten Will, V. Helms, 2016, Bioinform..

A better brain? Alternative spliced STIM2 in hominoids arises with synapse formation and creates a gain-of-function variant

V. Helms, B. Niemeyer, T. Tschernig, 2023, bioRxiv.

Quantitative study of BSA coating silica nanoparticle

V. Helms, D. Baowan, 2014, Journal of Mathematical Chemistry.

Energetics of liposomes encapsulating silica nanoparticles

A. Kraegeloh, V. Helms, D. Baowan, 2013, Journal of Molecular Modeling.

Assembly of transmembrane helices of simple polytopic membrane proteins from sequence conservation patterns

Yungki Park, Volkhard Helms, V. Helms, 2006, Proteins.

Cyclophilin A Binds to Linear Peptide Motifs Containing a Consensus That Is Present in Many Human Proteins*

D. Labudde, V. Helms, C. Freund, 2005, Journal of Biological Chemistry.

The ER Protein Translocation Channel Subunit Sbh1 Controls Virulence of Cryptococcus neoformans

T. Doering, V. Helms, J. Geddes-McAlister, 2022, bioRxiv.

PRIMSIPLR: Prediction of inner‐membrane situated pore‐lining residues for alpha‐helical transmembrane proteins

Po-Hsien Lee, Volkhard Helms, Duy Nguyen, 2014, Proteins.

Proton Travel in Green Fluorescent Protein

V. Helms, W. Gu, 2011 .

Transport of soluble proteins through the Golgi occurs by diffusion via continuities across cisternae

A. Luini, V. Helms, M. Sallese, 2014, eLife.

Conformational Transitions of Proteins from Atomistic Simulations

J. Andrew McCammon, Volkhard Helms, J. Mccammon, 1999, Computational Molecular Dynamics.

Statistical analysis and exposure status classification of transmembrane beta barrel residues

Yungki Park, Volkhard Helms, Sikander Hayat, 2011, Comput. Biol. Chem..

Dynamic protonation equilibrium of solvated acetic acid.

T. Straatsma, V. Helms, W. Gu, 2007, Angewandte Chemie.

Energy barriers of proton transfer reactions between amino acid side chain analogs and water from ab initio calculations

Volkhard Helms, Elena Herzog, Tomaso Frigato, 2006, J. Comput. Chem..

Synthesis, Biological Evaluation and Docking Studies of Ring-Opened Analogues of Ipomoeassin F

S. High, V. Helms, B. Hall, 2022, Molecules.

Biology-directed and in silico -aided design liberates a potent, simplified and ipomoeassin-F-derived Sec61 inhibitor

S. High, V. Helms, B. Hall, 2022 .

Molecular Modeling of Signal Peptide Recognition by Eukaryotic Sec Complexes

V. Helms, Pratiti Bhadra, 2021, International journal of molecular sciences.

How does Sec63 affect the conformation of Sec61 in yeast?

V. Helms, Pratiti Bhadra, K. Römisch, 2021, PLoS Comput. Biol..

Dysregulation of cholesterol homeostasis in human lung cancer tissue and tumour-associated macrophages

Marcel H. Schulz, J. Walter, V. Helms, 2021, EBioMedicine.

Relative Principal Components Analysis: Application to Analyzing Biomolecular Conformational Changes

Volkhard Helms, Thomas Lengauer, Mazen Ahmad, 2018, bioRxiv.

Conserved Gating Elements in TRPC4 and TRPC5 Channels*

A. Beck, V. Flockerzi, U. Wissenbach, 2013, The Journal of Biological Chemistry.

Phosphoryl transfer by a concerted reaction mechanism in UMP/CMP‐kinase

V. Helms, M. Hutter, 2000, Protein science : a publication of the Protein Society.

Influence of key residues on the reaction mechanism of the cAMP‐dependent protein kinase

V. Helms, M. Hutter, 1999, Protein science : a publication of the Protein Society.

Protein dynamics tightly connected to the dynamics of surrounding and internal water molecules.

Volkhard Helms, V. Helms, 2007, Chemphyschem : a European journal of chemical physics and physical chemistry.

Transient pockets on XIAP-BIR2: toward the characterization of putative binding sites of small-molecule XIAP inhibitors

Volkhard Helms, José L. Medina-Franco, Susanne Eyrisch, 2012, Journal of Molecular Modeling.

Free energies of hydration from thermodynamic integration: Comparison of molecular mechanics force fields and evaluation of calculation accuracy

Volkhard Helms, Rebecca C. Wade, R. Wade, 1997, J. Comput. Chem..

Molecular dynamics simulation of truncated bovine adrenodoxin

V. Helms, W. Gu, Saurabh Kumar Shakya, 2005, Biopolymers.

How phosphorylation of peptides affects their interaction with 14‐3‐3η domains

V. Helms, Nicolas Künzel, 2021, Proteins.

Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import

F. Förster, H. Freeze, V. Helms, 2018, Nature Communications.

Unspecific CTL Killing Is Enhanced by High Glucose via TNF-Related Apoptosis-Inducing Ligand

F. Lammert, Arne Knörck, V. Helms, 2022, Frontiers in Immunology.

High glucose enhances antigen-independent CTL killing via TRAIL

F. Lammert, Arne Knörck, V. Helms, 2021 .

Metabolic reprogramming of cytotoxic T lymphocytes by high glucose enhances pancreatic beta cell apoptosis via TRAIL

F. Lammert, Arne Knörck, V. Helms, 2021 .

Rule–based regulatory and metabolic model for Quorum sensing in P. aeruginosa

Volkhard Helms, Rolf W. Hartmann, Nadine S. Schaadt, 2013, BMC Systems Biology.

Batch tautomer generation with MolTPC

Volkhard Helms, Michael C. Hutter, Thorsten Will, 2013, J. Comput. Chem..

Proton shuttle in green fluorescent protein studied by dynamic simulations

M. Lill, V. Helms, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Identification of signal peptide features for substrate specificity in human Sec62/Sec63‐dependent ER protein import

F. Förster, Nagarjuna Nagaraj, A. Cavalié, 2020, The FEBS journal.

Effect of Sec62 on the conformation of the Sec61 channel in yeast.

V. Helms, Pratiti Bhadra, K. Römisch, 2022, Biochimica et biophysica acta. Biomembranes.

TRAM1 protein may support ER protein import by modulating the phospholipid bilayer near the lateral gate of the Sec61-channel

F. Förster, V. Helms, R. Zimmermann, 2020, Channels.

Proteomics identifies signal peptide features determining the substrate specificity in human Sec62/Sec63-dependent ER protein import

F. Förster, Nagarjuna Nagaraj, A. Cavalié, 2019, bioRxiv.

A Structural Model of the Complex Formed by Phospholamban and the Calcium Pump of Sarcoplasmic Reticulum Obtained by Molecular Mechanics

J. Meiler, C. Griesinger, V. Helms, 2002, Chembiochem : a European journal of chemical biology.

A spatial model of the chromatophore vesicles of Rhodobacter sphaeroides and the position of the Cytochrome bc1 complex.

V. Helms, T. Geyer, 2006, Biophysical Journal.

Atomistic simulation of water percolation and proton hopping in Nafion fuel cell membrane.

R. Rousseau, M. Dupuis, V. Helms, 2010, The journal of physical chemistry. B.

A Brownian dynamics study: the effect of a membrane environment on an electron transfer system.

V. Helms, D. Flöck, 2004, Biophysical journal.

Prediction of the Exposure Status of transmembrane beta Barrel residues from protein Sequence

Yungki Park, Volkhard Helms, Peter Walter, 2011, J. Bioinform. Comput. Biol..

Protein--protein docking of electron transfer complexes: cytochrome c oxidase and cytochrome c.

V. Helms, D. Flöck, 2002 .

ER import of small human presecretory proteins: components and mechanisms

V. Helms, R. Zimmermann, Sven Lang, 2019, FEBS letters.

Graph‐theoretical identification of dissociation pathways on free energy landscapes of biomolecular interaction

Volkhard Helms, Ling Wang, Boris Stumm, 2009, J. Comput. Chem..

Bridging the Gap: Linking Molecular Simulations and Systemic Descriptions of Cellular Compartments

V. Helms, T. Geyer, Xavier Mol, 2010, PloS one.

Compact parameter set for fast estimation of proton transfer rates

Volkhard Helms, Markus A. Lill, M. Lill, 2001 .

Molecular dynamics simulation of proton transport with quantum mechanically derived proton hopping rates (Q-HOP MD)

Volkhard Helms, Markus A. Lill, M. Lill, 2001 .

ALLO: A tool to discriminate and prioritize allosteric pockets

Volkhard Helms, Rahmad Akbar, R. Akbar, 2018, Chemical biology & drug design.

Brownian dynamics simulations of simplified cytochrome c molecules in the presence of a charged surface.

V. Helms, T. Geyer, V Helms, 2004, The Journal of chemical physics.

Diffusional encounter of barnase and barstar.

Volkhard Helms, Rebecca C Wade, R. Wade, 2006, Biophysical journal.

Attraction within the membrane

Volkhard Helms, V. Helms, 2002, EMBO reports.

Determinants of ligand binding to cAMP-dependent protein kinase.

J A McCammon, S. Taylor, J. Mccammon, 1999, Biochemistry.

IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype

V. Helms, J. Haybaeck, A. Kiemer, 2015, Cell Death and Disease.

Molecular dynamics of mouse acetylcholinesterase complexed with huperzine A.

J A McCammon, T P Straatsma, T. Straatsma, 1999, Biopolymers.

ENRI: A tool for selecting structure‐based virtual screening target conformations

Volkhard Helms, Siti Azma Jusoh, Rommie E. Amaro, 2017, Chemical biology & drug design.

Lanthanum ions inhibit the mammalian Sec61 complex in its channel dynamics and protein transport activity

V. Helms, Susanne Eyrisch, M. Jung, 2009, FEBS letters.

ERAD and protein import defects in a sec61 mutant lacking ER-lumenal loop 7

K. Kalies, V. Helms, Ozlem Ulucan, 2013, BMC Cell Biology.

Diffusional Dynamics of Cytochrome cMolecules in the Presence of a Charged Surface

V. Helms, C. Gorba, C. Gorba, 2003 .

Mycolactone enhances the Ca2+ leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state

A. Cavalié, V. Helms, B. Hall, 2021, Biochemical Journal.

Structural changes in cytochrome P-450cam effected by the binding of the enantiomers (1R)-camphor and (1S)-camphor.

R. Wade, G. H. Hoa, V. Helms, 1996, Biochemistry.

Optimized Data Set and Feature Construction for Substrate Prediction of Membrane Transporters

V. Helms, Andrea Denger, 2022, J. Chem. Inf. Model..

Dynamics of protein-protein encounter: a Langevin equation approach with reaction patches.

U. Schwarz, V. Helms, J. Schluttig, 2008, The Journal of chemical physics.

Transferring functional annotations of membrane transporters on the basis of sequence similarity and sequence motifs

V. Helms, A. Barghash, Ahmad Barghash, 2013, BMC Bioinformatics.

Classifying Substrate Specificities of Membrane Transporters from Arabidopsis thaliana

Volkhard Helms, Jan Christoph, Nadine S. Schaadt, 2010, J. Chem. Inf. Model..

Electronic excitations of biomolecules studied by quantum chemistry.

V. Helms, 2002, Current opinion in structural biology.

Randomization Strategies Affect Motif Significance Analysis in TF-miRNA-Gene Regulatory Networks

Volkhard Helms, Christian Spaniol, Maryam Nazarieh, 2017, J. Integr. Bioinform..

On the derivation of propensity scales for predicting exposed transmembrane residues of helical membrane proteins.

V. Helms, Yungki Park, 2007, Bioinformatics.

How strongly do sequence conservation patterns and empirical scales correlate with exposure patterns of transmembrane helices of membrane proteins?

Yungki Park, Volkhard Helms, V. Helms, 2006, Biopolymers.

The ABC (Analysing Biomolecular Contacts)-database

Volkhard Helms, Peter Walter, Sam Ansari, 2007, J. Integr. Bioinform..

Dynamical properties of fasciculin‐2

Nathan A. Baker, J A McCammon, V. Helms, 1999, Proteins.

Differential exon usage of developmental genes is associated with deregulated epigenetic marks

V. Helms, S. Shanak, A. Barghash, 2023, Scientific reports.

Mechanism of phosphoryl transfer in kinases investigated by semiempirical calculations

Volkhard Helms, Michael C. Hutter, V. Helms, 2003 .

Identification of Biomarkers Controlling Cell Fate In Blood Cell Development pdf

Volkhard Helms, Maryam Nazarieh, Marc P. Hoeppner, 2020, Frontiers in Bioinformatics.

TFmiR: a web server for constructing and analyzing disease-specific transcription factor and miRNA co-regulatory networks

Volkhard Helms, Mohamed Hamed, Christian Spaniol, 2015, Nucleic Acids Res..

Identification of key player genes in gene regulatory networks

Volkhard Helms, Mohamed Hamed, Andreas Wiese, 2016, BMC Systems Biology.

Graph Measures Reveal Fine Structure of Complexes Forming in Multiparticle Simulations.

Volkhard Helms, Tihamér Geyer, Florian Lauck, 2009, Journal of chemical theory and computation.

Molecular stochastic simulations of chromatophore vesicles from Rhodobacter sphaeroides.

V. Helms, T. Geyer, Florian Lauck, 2007, Journal of biotechnology.

Helical integrity and microsolvation of transmembrane domains from Flaviviridae envelope glycoproteins.

V. Helms, S. A. Jusoh, 2011, Biochimica et biophysica acta.

Differential analysis of combinatorial protein complexes with CompleXChange

Volkhard Helms, Thorsten Will, V. Helms, 2019, BMC Bioinformatics.

Association of cytochrome c with membrane-bound cytochrome c oxidase proceeds parallel to the membrane rather than in bulk solution.

Volkhard Helms, V. Helms, Alexander Spaar, 2009, Biophysical journal.

Different protonation equilibria of 4-methylimidazole and acetic acid.

V. Helms, W. Gu, 2007, Chemphyschem : a European journal of chemical physics and physical chemistry.

On the derivation of propensity scales for predicting exposed transmembrane residues of helical membrane proteins

V. Helms, Yungki Park, 2007, Bioinform..

Robust Detection of Outlier Samples and Genes in Expression Datasets

Volkhard Helms, Ahmad Barghash, Taner Arslan, 2016 .

Graph-Based Clustering of Predicted Ligand-Binding Pockets on Protein Surfaces

Volkhard Helms, Jennifer Degac, Uwe Winter, 2015, J. Chem. Inf. Model..

Monte Carlo simulation of biomolecular systems with BIOMCSIM

Hiqmet Kamberaj, Volkhard Helms, H. Kamberaj, 2001 .

Solvation free energies and transfer free energies for amino acids from hydrophobic solution to water solution from a very simple residue model

Volkhard Helms, Wei Gu, Sahand Jamal Rahi, 2004 .

Lipid metabolism signatures in NASH-associated HCC.--letter.

V. Helms, A. Kiemer, S. Kessler, 2014, Cancer research.