A. Aronheim

发表

Dimerization of the adaptor Gads facilitates antigen receptor signaling by promoting the cooperative binding of Gads to the adaptor LAT

O. Lewinson, Maria P. Frushicheva, Sigalit Sukenik, 2017, Science Signaling.

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway

Michael Karin, Nanxin Li, Joseph Schlessinger, 1994, Cell.

Alterations in the Expression of Transcription Factors and the Reduced Folate Carrier as a Novel Mechanism of Antifolate Resistance in Human Leukemia Cells*

Y. Assaraf, A. Aronheim, L. Rothem, 2003, The Journal of Biological Chemistry.

Heparanase is required for activation and function of macrophages

Y. Shaked, A. Aronheim, I. Vlodavsky, 2016, Proceedings of the National Academy of Sciences.

The cardiac maladaptive ATF3-dependent cross-talk between cardiomyocytes and macrophages is mediated by the IFNγ-CXCL10-CXCR3 axis.

A. Aronheim, L. Koren, U. Barash, 2017, International journal of cardiology.

Identification and analysis of PH domain‐containing targets of phosphatidylinositol 3‐kinase using a novel in vivo assay in yeast

R. Abagyan, A. Aronheim, M. Lemmon, 1998, The EMBO journal.

The Role of Basic Leucine Zipper Protein‐Mediated Transcription in Physiological and Pathological Myocardial Hypertrophy

A. Aronheim, I. Kehat, T. Hasin, 2006, Annals of the New York Academy of Sciences.

RalA interacts with ZONAB in a cell density‐dependent manner and regulates its transcriptional activity

C. Marshall, A. Aronheim, P. Frankel, 2005, The EMBO journal.

Cardiac Remodeling in the Absence of Cardiac Contractile Dysfunction Is Sufficient to Promote Cancer Progression

A. Aronheim, Lama Awwad, Tomer Goldenberg, 2022, Cells.

Induction of Terminal Differentiation by the c-Jun Dimerization Protein JDP2 in C2 Myoblasts and Rhabdomyosarcoma Cells*

A. Aronheim, O. Ostrovsky, E. Bengal, 2002, The Journal of Biological Chemistry.

B-cell factor 1 is required for optimal expression of the DRA promoter in B cells

B. Peterlin, C. Voliva, A. Aronheim, 1992, Molecular and cellular biology.

A Novel Specific Role for IκB Kinase Complex-associated Protein in Cytosolic Stress Signaling*

A. Aronheim, M. Jäättelä, T. Kallunki, 2002, The Journal of Biological Chemistry.

Insulin-producing cells contain a cell-specific repressor activity that functions through multiple E-box sequences.

A. Aronheim, D. Leshkowitz, M. Walker, 1992, DNA and cell biology.

A cDNA from a mouse pancreatic beta cell encoding a putative transcription factor of the insulin gene.

A. Aronheim, M. Walker, A. Rosén, 1990, Nucleic acids research.

The Cholinergic Binding Site: From Sequence to Function

J. Gershoni, A. Aronheim, I. Rusu, 1989 .

The AP‐1 repressor, JDP2, is a bona fide substrate for the c‐Jun N‐terminal kinase

A. Aronheim, S. Katz, R. Heinrich, 2001, FEBS letters.

Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp.

A. Aronheim, D. Yablonski, E. Manser, 2007, The Biochemical journal.

c-Jun dimerization protein 2 (JDP2) deficiency promotes cardiac hypertrophy and dysfunction in response to pressure overload.

R. Shofti, A. Aronheim, E. Suss-Toby, 2017, International journal of cardiology.

Host JDP2 expression in the bone marrow contributes to metastatic spread

Tsonwin Hai, Y. Shaked, A. Aronheim, 2015, Oncotarget.

Inhibition of AP-1 signaling by JDP2 overexpression protects cardiomyocytes against hypertrophy and apoptosis induction.

P. Ferdinandy, A. Aronheim, R. Schulz, 2013, Cardiovascular research.

Induction of heparanase 2 (Hpa2) expression by stress is mediated by ATF3.

Preeti Singh, A. Aronheim, R. Sanderson, 2021, Matrix Biology.

Towards an Understanding and use of the Cholinergic Binding Site

J. Gershoni, A. Aronheim, I. Rusu, 1989 .

Molecular decoys: ligand-binding recombinant proteins protect mice from curarimimetic neurotoxins.

J. Gershoni, A. Aronheim, 1988, Proceedings of the National Academy of Sciences of the United States of America.

A SWI2/SNF2‐type ATPase/helicase protein, mDomino, interacts with myeloid zinc finger protein 2A (MZF‐2A) to regulate its transcriptional activity

S. Nagata, R. Fukunaga, A. Aronheim, 2003, Genes to cells : devoted to molecular & cellular mechanisms.

HBV X protein targets HIV Tat-binding protein 1.

Y. Shaul, A. Aronheim, O. Barak, 2001, Virology.

The AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in mice

A. Aronheim, E. Pikarsky, K. Bitton-Worms, 2010, Molecular Cancer.

The C-terminal (BRCT) Domains of BRCA1 Interact in Vivo with CtIP, a Protein Implicated in the CtBP Pathway of Transcriptional Repression*

A. Bowcock, A. Aronheim, Leeju C. Wu, 1998, The Journal of Biological Chemistry.

The Prodomain of a Secreted Hydrophobic Mini-protein Facilitates Its Export from the Endoplasmic Reticulum by Hitchhiking on Sorting Receptors*

N. Kowalsman, A. Aronheim, Kazuki Sato, 2003, Journal of Biological Chemistry.

Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions

S. Elledge, E. Zandi, M. Karin, 1997, Molecular and cellular biology.

IL-31 induces antitumor immunity in breast carcinoma

S. Shen-Orr, Y. Shaked, A. Aronheim, 2020, Journal for ImmunoTherapy of Cancer.

Phosphorylation of JDP2 on threonine-148 by the c-Jun N-terminal kinase targets it for proteosomal degradation.

A. Aronheim, L. Koren, Keren Weidenfeld-Baranboim, 2011, The Biochemical journal.

The E2A gene product contains two separable and functionally distinct transcription activation domains.

A. Aronheim, M. Walker, A. Rosén, 1993, Proceedings of the National Academy of Sciences of the United States of America.

ATF3 and JDP2 deficiency in cancer associated fibroblasts promotes tumor growth via SDF-1 transcription

Y. Shaked, A. Aronheim, B. Korin, 2019, Oncogene.

AP-1 Repressor Protein JDP-2: Inhibition of UV-Mediated Apoptosis through p53 Down-Regulation

M. Karin, F. Piu, A. Aronheim, 2001, Molecular and Cellular Biology.

ATF3 expression in cardiomyocytes preserves homeostasis in the heart and controls peripheral glucose tolerance

Tsonwin Hai, A. Aronheim, L. Koren, 2017, Cardiovascular research.

Correction: Adult Cardiac Expression of the Activating Transcription Factor 3, ATF3, Promotes Ventricular Hypertrophy

Tsonwin Hai, A. Aronheim, I. Kehat, 2013, PloS one.

Adult Cardiac Expression of the Activating Transcription Factor 3, ATF3, Promotes Ventricular Hypertrophy

Tsonwin Hai, A. Aronheim, I. Kehat, 2013, PloS one.

An activation domain of the helix-loop-helix transcription factor E2A shows cell type preference in vivo in microinjected zebra fish embryos

A. Aronheim, Y. Arava, F. Argenton, 1996, Molecular and cellular biology.

Jun Dimerization Protein 2 Functions as a Progesterone Receptor N-Terminal Domain Coactivator

D. Edwards, J. Adelman, A. Aronheim, 2002, Molecular and Cellular Biology.

Early Cardiac Remodeling Promotes Tumor Growth and Metastasis

R. Shofti, A. Shiran, Y. Shaked, 2020, Circulation.

A novel approach for the identification of protein-protein interaction with integral membrane proteins.

A. Aronheim, G. Yudkovsky, M Hubsman, 2001, Nucleic acids research.

The Ras recruitment system, a novel approach to the study of protein–protein interactions

A. Aronheim, Sigal Katz, Y. Broder, 1998, Current Biology.

The Ras Recruitment System (RRS) for the Identification and Characterization of Protein-Protein Interactions.

A. Aronheim, 2018, Methods in molecular biology.

Ras signaling pathway for analysis of protein-protein interactions in yeast and mammalian cells.

A. Aronheim, Ami Aronheim, 2004, Methods in molecular biology.

Protein recruitment systems for the analysis of protein +/- protein interactions.

A. Aronheim, 2001, Methods.

Protein recruitment systems for the analysis of protein-protein interactions.

A. Aronheim, 2000, Biochemical pharmacology.

Analysis and identification of protein-protein interactions using protein recruitment systems.

M. Karin, A. Aronheim, 2000, Methods in Enzymology.

Angiotensin II signaling up-regulates the immediate early transcription factor ATF3 in the left but not the right atrium

Tsonwin Hai, A. Aronheim, Z. Abassi, 2010, Basic Research in Cardiology.

Inhibition of basic leucine zipper transcription is a major mediator of atrial dilatation.

A. Aronheim, J. Gutkind, H. Miyazaki, 2006, Cardiovascular research.

Chp, a homologue of the GTPase Cdc42Hs, activates the JNK pathway and is implicated in reorganizing the actin cytoskeleton

A. Abo, A. Aronheim, A. Fritsch, 1998, Current Biology.

Ras signaling pathway for analysis of protein-protein interactions.

A. Aronheim, 2001, Methods in enzymology.

A novel in vivo assay for the analysis of protein-protein interaction

Marlene Maroun, Ami Aronheim, A. Aronheim, 1999, Nucleic Acids Res..

The Sos recruitment system for identification of protein partners: a basic screening protocol

A. Aronheim, Yael Tamir, 1998 .

A SWI 2 / SNF 2-type ATPase / helicase protein , mDomino , interacts with myeloid zinc finger protein 2 A ( MZF-2 A ) to regulate its transcriptional activity

S. Nagata, R. Fukunaga, A. Aronheim, 2003 .

The ubiquitously expressed bZIP inhibitor, JDP2, suppresses the transcription of its homologue immediate early gene counterpart, ATF3

A. Aronheim, K. Yokoyama, T. Hasin, 2009, Nucleic acids research.

TRE-dependent transcription activation by JDP2–CHOP10 association

A. Aronheim, K. Bitton-Worms, Keren Weidenfeld-Baranboim, 2008, Nucleic acids research.

Partial oncogenic transformation of chicken embryo fibroblasts by Jun dimerization protein 2, a negative regulator of TRE- and CRE-dependent transcription

P. Vogt, M. Aoki, A. Aronheim, 2003, Oncogene.

ATF3-dependent cross-talk between cardiomyocytes and macrophages promotes cardiac maladaptive remodeling.

Tsonwin Hai, Y. Shaked, A. Aronheim, 2015, International journal of cardiology.

The c-Jun Dimerization Protein 2 Inhibits Cell Transformation and Acts as a Tumor Suppressor Gene*

A. Aronheim, Erella Livne, E. Livne, 2004, Journal of Biological Chemistry.

WDR62 mediates TNFα-dependent JNK activation via TRAF2-MLK3 axis

A. Aronheim, Sharon Aviram, Elad Prinz, 2018, Molecular biology of the cell.

Increased risk of non-hematological cancer in young patients with aortic stenosis: a retrospective cohort study

A. Shiran, A. Aronheim, T. Bental, 2021, Cardio-Oncology.

Cardiac Dysfunction Promotes Cancer Progression via Multiple Secreted Factors

A. Aronheim, Lama Awwad, 2022, Cancer research.

Improved efficiency sos recruitment system: expression of the mammalian GAP reduces isolation of Ras GTPase false positives.

A. Aronheim, A Aronheim, 1997, Nucleic acids research.

Docking interactions of the JNK scaffold protein WDR62

A. Aronheim, A. Whitmarsh, Samer Khateb, 2011, The Biochemical journal.

A Novel c-Jun N-terminal Kinase (JNK)-binding Protein WDR62 Is Recruited to Stress Granules and Mediates a Nonclassical JNK Activation

A. Aronheim, T. Hasin, K. Katsenelson, 2010, Molecular biology of the cell.

Characterization of the binding of alpha-bungarotoxin to bacterially expressed cholinergic binding sites.

J. Gershoni, A. Aronheim, Y. Eshel, 1988, The Journal of biological chemistry.

Distribution and characterization of helix-loop-helix enhancer-binding proteins from pancreatic beta cells and lymphocytes.

A. Aronheim, M. Walker, C. W. Park, 1991, Nucleic acids research.

JDP2 and ATF3 deficiencies dampen maladaptive cardiac remodeling and preserve cardiac function

Tsonwin Hai, R. Shofti, A. Aronheim, 2019, PloS one.

Positive and negative regulation of insulin gene transcription.

A. Aronheim, D. Leshkowitz, M. Walker, 1993, Biochemical Society transactions.

The bZIP repressor proteins, c-Jun dimerization protein 2 and activating transcription factor 3, recruit multiple HDAC members to the ATF3 promoter.

Tsonwin Hai, A. Aronheim, K. Yokoyama, 2012, Biochimica et biophysica acta.

Direct measurement of agonist binding to genetically engineered peptides of the acetylcholine receptor by selective T1 NMR relaxation.

J. Gershoni, G. Navon, A. Aronheim, 1990, Biochemistry.

Differential targeting of the stress mitogen-activated protein kinases to the c-Jun dimerization protein 2.

A. Aronheim, Sigal Katz, 2002, The Biochemical journal.

The association of the JNK scaffold protein, WDR62, with the mixed lineage kinase 3, MLK3

A. Aronheim, A. Whitmarsh, Ilona Darlyuk-Saadon, 2015 .

Lack of Plasma Membrane Targeting of a G172D Mutant Thiamine Transporter Derived from Rogers Syndrome Family

Y. Assaraf, A. Aronheim, N. Cohen, 2002, Molecular medicine.

Identification and Analysis of a Novel Dimerization Domain Shared by Various Members of c-Jun N-terminal Kinase (JNK) Scaffold Proteins*

F. Glaser, A. Aronheim, Alona Rabner, 2013, The Journal of Biological Chemistry.

Cell-specific expression of helix-loop-helix transcription factors encoded by the E2A gene.

A. Aronheim, M. Walker, A Aronheim, 1993, Nucleic acids research.

Tumor Growth Ameliorates Cardiac Dysfunction and Suppresses Fibrosis in a Mouse Model for Duchenne Muscular Dystrophy.

A. Aronheim, Laris Achlaug, Lama Awwad, 2023, International journal of molecular sciences.

Tumor Growth Ameliorates Cardiac Dysfunction

R. Shofti, A. Aronheim, Lama Awwad, 2023, Cells.

Proimflammatory cytokines and vascular endothelial growth factor levels at the peripheral and coronary atherosclerosis

Tsonwin Hai, A. Aronheim, L. Koren, 2016 .

Activating Transcription 3's role in cardiac remodeling.

A. Aronheim, L. Koren, R. Kalfon, 2017, International journal of cardiology.

ATF3, a novel cardiac therapeutic target: Beneficial or harmful?

A. Aronheim, L. Koren, R. Kalfon, 2017, International journal of cardiology.

Disruption of transport activity in a D93H mutant thiamine transporter 1, from a Rogers Syndrome family.

Y. Assaraf, A. Aronheim, S. Drori, 2003, European journal of biochemistry.

Membrane recruitment systems for analysis of protein-protein interactions.

A. Aronheim, 2001, Methods in molecular biology.