J. Jansonius

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X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase.

C. Mcphalen, M. Vincent, J. Jansonius, 1993, Journal of molecular biology.

2.0 A structure of indole-3-glycerol phosphate synthase from the hyperthermophile Sulfolobus solfataricus: possible determinants of protein stability.

M. Hennig, R. Sterner, K. Kirschner, 1995, Structure.

Three-dimensional structure of the bifunctional enzyme phosphoribosylanthranilate isomerase: indoleglycerolphosphate synthase from Escherichia coli refined at 2.0 A resolution.

M Wilmanns, T. Niermann, M. Wilmanns, 1992, Journal of molecular biology.

The Crystal Structure of Indoleglycerol-phosphate Synthase from Thermotoga maritima

K. Kirschner, J. Jansonius, T. Knöchel, 2002, The Journal of Biological Chemistry.

Repeated seeding technique for growing large single crystals of proteins.

G. Eichele, C. Thaller, J. Jansonius, 1981, Journal of molecular biology.

Crystal Structures of Thioredoxins f and m from Spinach Chloroplasts

P. Schürmann, G. Capitani, J. Jansonius, 1998 .

The catalytic mechanism of indole-3-glycerol phosphate synthase: crystal structures of complexes of the enzyme from Sulfolobus solfataricus with substrate analogue, substrate, and product.

M. Hennig, K. Kirschner, J. Jansonius, 2002, Journal of molecular biology.

Crystal structure of concanavalin B at 1.65 A resolution. An "inactivated" chitinase from seeds of Canavalia ensiformis.

M. Hennig, B. Dijkstra, J. Jansonius, 1995, Journal of molecular biology.

The structure of OmpF porin in a tetragonal crystal form.

J. Jenkins, J. Rosenbusch, E. Pai, 1995, Structure.

Crystal structures explain functional properties of two E. coli porins

G. Rummel, S. Cowan, M. Steiert, 1992, Nature.

Structure, evolution and action of vitamin B6-dependent enzymes.

J. Jansonius, J N Jansonius, 1998, Current opinion in structural biology.

Crystallization and preliminary X-ray analysis of pig kidney DOPA decarboxylase.

V. Malashkevich, J. Jansonius, U. Sauder, 1992, Journal of molecular biology.

Structural conservation in parallel beta/alpha-barrel enzymes that catalyze three sequential reactions in the pathway of tryptophan biosynthesis.

M Wilmanns, D. Davies, M. Wilmanns, 1991, Biochemistry.

Crystallization and preliminary X-ray analysis of γ-aminobutyric acid transaminase

J. Jansonius, Tilman Schirmer, Z. Marković-Housley, 1990 .

Crystallization and preliminary X‐ray crystallographic data of the bifunctional enzyme phosphoribosyl‐anthranilate isomerase—indole‐3‐glycerol‐phosphate synthase from Escherichia coli

C. Thaller, M. Grütter, K. Kirschner, 1982 .

Three-dimensional structure of the bifunctional enzyme N-(5'-phosphoribosyl)anthranilate isomerase-indole-3-glycerol-phosphate synthase from Escherichia coli.

T. Jardetzky, M. Grütter, K. Kirschner, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Crystallization and structure solution at 4 A resolution of the recombinant synthase domain of N-(5'-phosphoribosyl)anthranilate isomerase:indole-3-glycerol-phosphate synthase from Escherichia coli complexed to a substrate analogue.

M. Wilmanns, J. Jansonius, E. Schlagenhauf, 1990, Protein engineering.

Structure of a novel extracellular Ca2+-binding module in BM-40

R. Timpl, J. Engel, J. Jansonius, 1996, Nature Structural Biology.

The structure of thermolysin: an electron density map at 2-3 A resolution.

B. Matthews, P. Colman, J. Jansonius, 1972, Journal of molecular biology.

The structure of papain.

J. Drenth, J. Jansonius, R. Koekoek, 1971, Advances in protein chemistry.

Structure of the IIA domain of the mannose transporter from Escherichia coli at 1.7 angstroms resolution.

B. Erni, J. Jansonius, P. Rizkallah, 1996, Journal of molecular biology.

Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine.

G. Capitani, J. Jansonius, P. Storici, 1999, Journal of molecular biology.

Crystal Structure of GABA-Aminotransferase, a Target for Antiepileptic Drug Therapy†

G. Capitani, J. Jansonius, P. Storici, 1999 .

Three-dimensional structure of mitochondrial aspartate aminotransferase and some functional derivatives: implications for its mode of action.

G. Eichele, C. Thaller, P. Christen, 1984, Biochemical Society transactions.

Crystallization and preliminary X-ray analysis

J. Jansonius, 2002 .

Preliminary X-ray analysis of a new crystal form of recombinant pig kidney DOPA decarboxylase.

V. Malashkevich, P. Burkhard, J. Jansonius, 1999, Acta crystallographica. Section D, Biological crystallography.

Crystallization and preliminary X‐ray analysis of phosphoserine aminotransferase from Bacillus circulans subsp. alkalophilus

J. Jansonius, T. Korpela, N. Battchikova, 1996, Protein science : a publication of the Protein Society.

Crystallization and preliminary X-ray diffraction studies of dialkylglycine decarboxylase, a decarboxylating transaminase.

R. Pauptit, J. Jansonius, U. Sauder, 1991, Journal of molecular biology.

Trigonal crystals of porcine mitochondrial aspartate aminotransferase.

R. Pauptit, J. Jansonius, T. Izard, 1990, Journal of molecular biology.

Crystallization and preliminary X-ray studies of an aspartate aminotransferase mutant from Escherichia coli.

K. Kirschner, J. Jansonius, U. Sauder, 1989, Journal of molecular biology.

Crystallographic and Solution Studies on Phosphoserine Aminotransferase (PSAT) from E.coli

M. Vincent, J. Jansonius, M. Kania, 1987 .

Quaternary structure of ornithine aminotransferase in solution and preliminary crystallographic data.

A. Lustig, M. Vincent, J. Jansonius, 1987, European journal of biochemistry.

Isolation, crystallization and preliminary crystallographic data of aspartate aminotransferase from chicken heart mitochondria.

G. Eichele, C. Thaller, P. Christen, 1977, Journal of molecular biology.

Preliminary X-ray diffraction studies of orthorhombic crystals of superoxide dismutase from Bacillus stearothermophilus.

J. Jansonius, J. Smit, J. Pulver-Sladek, 1977, Journal of molecular biology.

Crystallisation and preliminary X‐ray diffraction studies of cyclophilin‐tetrapeptide and cyclophilin‐cyclosporin complexes

M. Walkinshaw, J. Jansonius, M. Zurini, 1990, FEBS letters.

Crystallographic studies on the vitamin B6-assisted enzymic transamination reaction

B. Shen, V. Malashkevich, M. Hennig, 1994 .

The structure of neutral protease from Bacillus cereus at 0.2-nm resolution.

K. Wilson, R. Pauptit, J. Jansonius, 1992, European journal of biochemistry.

Identification of an allosteric anion-binding site on O-acetylserine sulfhydrylase: structure of the enzyme with chloride bound.

P. Burkhard, J. Jansonius, P. Cook, 2000, Journal of molecular biology.

Alternating arginine-modulated substrate specificity in an engineered tyrosine aminotransferase

V. Malashkevich, J. Kirsch, J. Jansonius, 1995, Nature Structural Biology.

Mechanism of action of aspartate aminotransferase proposed on the basis of its spatial structure.

G. Eichele, P. Christen, J. Kirsch, 1984, Journal of molecular biology.

Crystal structures of Escherichia coli aspartate aminotransferase in two conformations. Comparison of an unliganded open and two liganded closed forms.

J. Jansonius, U. Sauder, J. Jäger, 1994, Journal of molecular biology.

Significant improvement to the catalytic properties of aspartate aminotransferase: role of hydrophobic and charged residues in the substrate binding pocket.

K. Kirschner, J. Jansonius, I. Fotheringham, 1994, Biochemistry.

Ligand binding induces a large conformational change in O-acetylserine sulfhydrylase from Salmonella typhimurium.

P. Burkhard, J. Jansonius, P. Cook, 1999, Journal of molecular biology.

Three-dimensional structure of O-acetylserine sulfhydrylase from Salmonella typhimurium.

P. Burkhard, Paul Cook, J. Jansonius, 1998, Journal of molecular biology.

Inhibition and Structural Changes of O-Acetylserine Sulfhydrylase-A from Salmonella typhimurium Upon Binding Sulfate and Chloride Anions

J. Jansonius, P. Cook, C. Tai, 2000 .

Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase

V. Malashkevich, P. Burkhard, J. Jansonius, 2001, Nature Structural Biology.

Structure of 1-aminocyclopropane-1-carboxylate synthase, a key enzyme in the biosynthesis of the plant hormone ethylene.

G Capitani, J. Kirsch, G. Capitani, 1999, Journal of molecular biology.

Three-dimensional structure of a pyridoxal-phosphate-dependent enzyme, mitochondrial aspartate aminotransferase.

G. Eichele, J. Jansonius, G. C. Ford, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Dialkylglycine decarboxylase structure: bifunctional active site and alkali metal sites.

S. Cowan, J. Jansonius, E. Hohenester, 1994, Science.

Changing the reaction specificity of a pyridoxal-5'-phosphate-dependent enzyme.

P. Christen, V. Malashkevich, J. Jansonius, 1995, European journal of biochemistry.

Structural and mechanistic analysis of two refined crystal structures of the pyridoxal phosphate-dependent enzyme dialkylglycine decarboxylase.

J. Jansonius, E. Hohenester, M. Toney, 1995, Journal of molecular biology.

Substitution of apolar residues in the active site of aspartate aminotransferase by histidine. Effects on reaction and substrate specificity.

P. Christen, V. Malashkevich, J. Jansonius, 1995, European journal of biochemistry.

Crystal structures of true enzymatic reaction intermediates: aspartate and glutamate ketimines in aspartate aminotransferase.

V. Malashkevich, J. Jansonius, M. Toney, 1994, Biochemistry.

13 Papain, X-Ray Structure

Jan Drenth, J. Drenth, J. Jansonius, 1971 .

Crystal structure of phosphoserine aminotransferase from Escherichia coli at 2.3 A resolution: comparison of the unligated enzyme and a complex with alpha-methyl-l-glutamate.

J. Jansonius, J. Kallen, Z. Marković-Housley, 1999, Journal of molecular biology.

Structure of Papain

J. Drenth, J. Jansonius, R. Koekoek, 1968, Nature.

An alkali metal ion size-dependent switch in the active site structure of dialkylglycine decarboxylase.

J. Jansonius, E. Hohenester, J. Keller, 1994, Biochemistry.

Crystal structure at 2.0 A resolution of phosphoribosyl anthranilate isomerase from the hyperthermophile Thermotoga maritima: possible determinants of protein stability.

M. Hennig, R. Sterner, K. Kirschner, 1997, Biochemistry.

Crystal structure of human recombinant ornithine aminotransferase.

B. Shen, M. Hennig, J. Jansonius, 1998, Journal of molecular biology.

Mutant aspartate aminotransferase (K258H) without pyridoxal-5'-phosphate-binding lysine residue. Structural and catalytic properties.

P. Christen, V. Malashkevich, R. Jaussi, 1993, European journal of biochemistry.

Structural comparison suggests that thermolysin and related neutral proteases undergo hinge-bending motion during catalysis.

D. R. Holland, B. Matthews, K. Flaherty, 1992, Biochemistry.

Three-dimensional structure of thermolysin.

B P Schoenborn, B. Matthews, B. Schoenborn, 1972, Nature: New biology.

Crystal structures of two functionally different thioredoxins in spinach chloroplasts.

P. Schürmann, G. Capitani, J. Jansonius, 2000, Journal of molecular biology.

Crystal structures of dialkylglycine decarboxylase inhibitor complexes.

V. Malashkevich, J. Jansonius, P. Strop, 1999, Journal of molecular biology.

The open/closed conformational equilibrium of aspartate aminotransferase. Studies in the crystalline state and with a fluorescent probe in solution.

C. Thaller, P. Christen, M. Vincent, 1991, European journal of biochemistry.

Evidence that 31P NMR is a sensitive indicator of small conformational changes in the coenzyme of aspartate aminotransferase.

M. Vincent, J. Jansonius, M. G. Vincent, 1989, European journal of biochemistry.

Phosphorus-31 Nuclear Magnetic Resonance Studies on Apoaspartate Aminotransferase Reconstituted with Cofactor Analogues

M. Vincent, J. Jansonius, K. Schnackerz, 1987 .

The three-dimensional structure of mitochondrial aspartate aminotransferase at 4.5 A resolution.

G. Eichele, P. Christen, J. Jansonius, 1979, Journal of molecular biology.

Enzyme Mechanism: What X-Ray Crystallography can(not) Tell Us

J. Jansonius, 1987 .

Domain closure in mitochondrial aspartate aminotransferase.

A M Lesk, C Chothia, A. Lesk, 1992, Journal of molecular biology.

X-ray diffraction analysis of matrix porin, an integral membrane protein from Escherichia coli outer membranes.

J. Jenkins, J. Rosenbusch, J. Jansonius, 1983, Journal of molecular biology.

A comparison of the three-dimensional structures of subtilisin BPN' and subtilisin novo.

J. Drenth, J. Jansonius, R. Koekoek, 1972, Cold Spring Harbor symposia on quantitative biology.

X-ray structure of a decameric cyclophilin-cyclosporin crystal complex

M. Walkinshaw, J. Jansonius, M. Zurini, 1993, Nature.

Crystal structure of neutral protease from Bacillus cereus refined at 3.0 A resolution and comparison with the homologous but more thermostable enzyme thermolysin.

J. Jenkins, R. Pauptit, J. Jansonius, 1988, Journal of molecular biology.

IV. Cysteine proteinases

J. Drenth, J. Jansonius, R. Koekoek, 1970 .

Structure of the papain molecule

J. Drenth, J. Jansonius, R. Koekoek, 1970 .

Subtilisin Novo. The three-dimensional structure and its comparison with subtilisin BPN'.

J. Drenth, J. Jansonius, R. Koekoek, 1972, European journal of biochemistry.

The crystal structure of papain: II. A three-dimensional fourier synthesis at 4.5 Å resolution

J. Drenth, J. Jansonius, B. G. Wolthers, 1967 .

The crystal structure of papain C

J. Drenth, J. Jansonius, R. Koekoek, 1962 .

Spatial Aspects of Catalysis by Mitochondrial Aspartate Aminotransferase

C. Mcphalen, M. Vincent, J. Jansonius, 1987 .

The double domain structure of rhodanese.

W G Hol, W. Hol, J. Jansonius, 1975, Journal of molecular biology.

Conversion of Aspartate Aminotransferase into anl-Aspartate β-Decarboxylase by a Triple Active-site Mutation*

P. Christen, V. Malashkevich, J. Jansonius, 1999, The Journal of Biological Chemistry.

Crystalline mitochondrial aspartate aminotransferase exists in only two conformations.

J. Jansonius, E. Hohenester, 1994, Journal of molecular biology.

The hyperthermostable indoleglycerol phosphate synthase from Thermotoga maritima is destabilized by mutational disruption of two solvent-exposed salt bridges.

K. Kirschner, J. Jansonius, T. Knöchel, 1999, Journal of molecular biology.

University of Groningen Crystal Structure of Concanavalin B at 1.65 Å Resolution. An ‘‘Inactivated’’ Chitinase from Seeds of Canavalia ensiformis Hennig,

M. Hennig, B. Dijkstra, J. Jansonius, 2022 .

A structure for thermolysin.

B. Matthews, K. Titani, P. Colman, 1972, Nature.

The crystal structure of anthranilate synthase from Sulfolobus solfataricus: functional implications.

R. Bauerle, M. Wilmanns, K. Kirschner, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure of glutamate-1-semialdehyde aminomutase: an alpha2-dimeric vitamin B6-dependent enzyme with asymmetry in structure and active site reactivity.

M. Hennig, J. Jansonius, B. Grimm, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the pyridoxal 5'-phosphate-binding lysine residue.

P. Christen, V. Malashkevich, J. Jansonius, 1994, Biochemistry.

Crystallization and preliminary X-ray analysis of wild-type and K272A mutant glutamate 1-semialdehyde aminotransferase from Synechococcus.

M. Hennig, J. Jansonius, M. Jenny, 1994, Journal of molecular biology.

X-ray Crystallographic Studies on E. coli Aspartate Aminotransferase Wild Type and Mutants

R. Pauptit, J. Jansonius, U. Sauder, 1991 .

Crystallization of pig mitochondrial aspartate aminotransferase by seeding with crystals of the chicken mitochondrial isoenzyme.

G. Eichele, J. Jansonius, G. C. Ford, 1979, Journal of Molecular Biology.

Catalytic activity in crystals of mitochondrial aspartate aminotransferase as detected by microspectrophotometry.

G. Eichele, P. Christen, J. Jansonius, 1978, The Journal of biological chemistry.

Diffraction methods for biological macromolecules. Seed enlargement and repeated seeding.

G. Eichele, C. Thaller, J. Jansonius, 1985, Methods in enzymology.

Crystal structures and solution studies of oxime adducts of mitochondrial aspartate aminotransferase.

P. Christen, J. Jansonius, E. Hohenester, 1996, European journal of biochemistry.

Complexes of aspartate aminotransferase with hydroxylamine derivatives: spectral studies in solution and in the crystalline state.

J. Jansonius, M. Karpeisky, J. Kallen, 1989, Biochimie.

Linear dichroism measurements on single crystals of the pyridoxal phosphate dependent enzyme mitochondrial aspartate aminotransferase

G. Eichele, P. Christen, M. Vincent, 1984 .

A common channel-forming motif in evolutionarily distant porins.

D. Tsernoglou, M. Parker, M. Weiss, 1991, Journal of structural biology.

The Three-Dimensional Structure of Phosphoserine Aminotransferase from Escherichia coli

J. Jansonius, M. Kania, J. Kallen, 1991 .

Trigonal crystals of porin from Escherichia coli.

G. Rummel, R. Pauptit, J. Jansonius, 1991, Journal of molecular biology.

TOWARDS THE SPATIAL STRUCTURE OF MITOCHONDRIAL ASPARTATE-AMINOTRANSFERASE

G. Eichele, C. Thaller, P. Christen, 1978 .

Crystallization and preliminary X-ray diffraction studies of the spinach-chloroplast thioredoxin f.

P. Schürmann, J. Jansonius, E. Hohenester, 1991, Journal of molecular biology.

The Unit Cell of Mercuripapain Crystals

J. Drenth, J. Jansonius, 1959, Nature.

Computational approach towards the three‐dimensional structure of E. coli tyrosine aminotransferase

T. Šolmajer, J. Jansonius, J. Jäger, 1992, FEBS letters.

Crystallization and preliminary X-ray analysis of phosphos~rine a~inotransf~rase from ~~ciZZ~s ci~c~Z~~s s~bs~. ~Z~~Zo~~iZ~s

J. Jansonius, N. Battchikova, M. Moser, 1996 .

Recent Studies on Mitochondrial Aspartate Aminotransferase: Structure & Mechanism

C. Mcphalen, M. Vincent, J. Jansonius, 1987 .

The Three-Dimensional Structure of Papain

J. Drenth, J. Jansonius, R. Koekoek, 1970 .

The molecular replacement solution and X-ray refinement to 2.8 A of a decameric complex of human cyclophilin A with the immunosuppressive drug cyclosporin A.

M. Walkinshaw, J. Jansonius, J. Kallen, 1994, Journal of molecular biology.

Crystallization and preliminary X-ray analysis of recombinant 1-aminocyclopropane-1-carboxylate synthase from apple. A key enzyme in the biosynthesis of the plant hormone ethylene.

M. F. White, J. Kirsch, J. Jansonius, 1994, Journal of molecular biology.

Crystallization and preliminary X-ray diffraction studies of the N-terminal domain of the phosphorylating subunit of mannose permease from Escherichia coli.

B. Erni, R. Pauptit, J. Jansonius, 1990, Journal of molecular biology.

Restrained Least-Squares Refinement of the Sulfhydryl Protease Papain to 2.0 Angstroms

Christina Thaller, C. Thaller, E. Mehler, 1985 .

Functional and structural analysis of cis-proline mutants of Escherichia coli aspartate aminotransferase.

V. Malashkevich, J. Jansonius, L. Birolo, 1999, Biochemistry.

Crystal structure of GABA-aminotransferase, a target for antiepileptic drug therapy.

J. Jansonius, D. Biase, Guido Capitani, 1999, Biochemistry.